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I think because the scar had that big black blood scab on it made it impossible for the bold guy to recovery right with the acell. if that scar was not sealed with that scab it would of maybe made a big difference. i bet he was applying acell on the top of that scab and it was getting deep into the wound to heal. I looked at the pictures of the animals and i see that the wounds dont have huge scabs blocking the acell.
Ive also been reading that useing acell on some animals it healed it but left a little scar, i think it was because the forumed a scab and it stop the acell from getting into it.
Idk its just a idea. if its true that a man regrew a finger then this will become some big in the future, just because this isnt going well with dr jones doesnt mean that its over.
also cats and humans are both mammals. both of us gets scars. the cat was cured. just think about us.
I believe Manning, the Acell rep, said that Acell was only applied the day of the excision.
Spoke with Manning, the Acell rep, and learned that Dr. Jones was trying to see if the wound would heal under the worst case scenario conditions. Manning admitted that the wound should have been kept moist and under a bandaged for several weeks and that acell should have been reapplied several times. I suppose Dr. Jones deviated from Acell's suggestions to see whether or not he could use acell on patients who are not able to return to him for frequent visits.
Manning also said that there are several docs using acell but that he is not at liberty to reveal who they are at this time.
Spoke with Manning, the Acell rep, and learned that Dr. Jones was trying to see if the wound would heal under the worst case scenario conditions. Manning admitted that the wound should have been kept moist and under a bandaged for several weeks and that acell should have been reapplied several times. I suppose Dr. Jones deviated from Acell's suggestions to see whether or not he could use acell on patients who are not able to return to him for frequent visits.
Manning also said that there are several docs using acell but that he is not at liberty to reveal who they are at this time.
It sounds like an excuse to me. But either way, it's good to hear that even Manning thought the Acell application was grossly mishandled.
who is this Manning and what does he do?
if this is true it was applied only once, then this trail was different from the dude that lost his finger, because the guy that lost his finger applied it every 2 days.
another question, why would mr jones only do it once, that makes no sense.
who is this Manning and what does he do?
if this is true it was applied only once, then this trail was different from the dude that lost his finger, because the guy that lost his finger applied it every 2 days.
another question, why would mr jones only do it once, that makes no sense.
Mike Manning is the Acell rep.
Regarding why Dr. Jones proceeded the way he did, I'll repeat what I wrote earlier "I suppose Dr. Jones deviated from Acell's suggestions to see whether or not he could use acell on patients who are not able to return to him for frequent visits."
who is this Manning and what does he do?
if this is true it was applied only once, then this trail was different from the dude that lost his finger, because the guy that lost his finger applied it every 2 days.
another question, why would mr jones only do it once, that makes no sense.
Mike Manning is the Acell rep.
Regarding why Dr. Jones proceeded the way he did, I'll repeat what I wrote earlier "I suppose Dr. Jones deviated from Acell's suggestions to see whether or not he could use acell on patients who are not able to return to him for frequent visits."
you would think that all he would want to know is if this stuff really stop scaring.
I am wondering if keeping an acell covered wound moist with hyaluronic acid in addition or instead of saline would be a better option than just saline alone. Anyone?
maybe, i think that if it was done right we would see better results.
i think its just like pimples, if you dont put on your acne medicine twice everyday the pimples will creep in, same goes with this. if you dont put on your acell every two days the scar tissue will creep in.
www.worldwidewounds.com/2005/august/Schultz/Extrace-Matric-Acute-Chronic-Wounds.html
http://www.worldwidewounds.com/2005/august...nic-Wounds.html
big article about ecm stuff.
i watch a video and they said that vets are using regenative medicine because its not so stricky regulated.
heres a link to a vet regenative medicine, watch the videos.
another link about it preventing scar tissue.
http://www.vet-stem.com/technologies/faq_detail.php?id=37
another article about how this stuff works.
http://health.howstuffworks.com/extracellular-matrix.htm
I am wondering if keeping an acell covered wound moist with hyaluronic acid in addition or instead of saline would be a better option than just saline alone. Anyone?
I've read Hyaluronic acid absorbs 1000 times its weight in water.
Also in the womb ECM will be kept moist by Hyaluronic acid
Mast et al.,18 however, found that the extracellular matrix of foetal wounds is rich in hyaluronic acid
If it's said ECM needs to be moist and that in the womb ECM is kept moist by hyluaronic acid???
In the womb ECM will be kept moist by Hyaluronic acid, why not use it on ECM?
Also it is said to inhibit excessive scarring and inflammation.
http://cat.inist.fr/?aModele=afficheN&cpsidt=2825675
Logically, the more your body has to do to heal will detract from the overall attainment of perfection in any given area. I caution to concentrate on large areas at once due to this simple fact. You can't throw any given miracle powder on a wound and expect something from it just because it did wonders for a cat. It is unreasonable to think that the same can be said for an unhealthy (not at all debatable) balding man or acne sufferer who most definitely has inhibited wound healing mechanisms to begin with. My point: aim for the fast and easy approach and see little improvement as opposed to the slow and perfected approach that will achieve the maximum in wound healing standard.
My views on acne in general are very harsh. I have pitted scarring that has been treated with a plethora of widely used applications. I blame myself and circumstance for what has happened to me. It is time that we own up and realize that it took us years to get to where we are and it will take years (after the discovery of a cure) to get to where we think we should be.
Logic for you.
The same ecm in cats is found in humans too, in reptiles, dogs, pigs.
ECM is not magic dust, it is a component that takes up 30% of your body, all ECM is, is an uncomplicated scaffold frame work with tiny holes and pores in it that our smart tissues use to grow through, something I've heard is like how a snake crawls through a trellis.
If these tiny holes are blocked by denaturing (e.g. a chemical additive has beeen added that has blocked a percentage of micro holes) our tissues can not grow through most of the holes. What will happen is the body will degrade and regenerate the ecm, and this time the ecm will not have tissue filling through these holes, this will bring an emergancy fibrotic response, you will get encapsulation and spots of fibrosis on the material. Think what happens when pores get blocked up, the same thing happens with ecm.
It is all down to denaturing wether or not you get perfect regeneration. Our regenerated tissues have needed ecm since birth/conception.
IMO it is not the more your body has to heal it is more like: if the ecm has been denatured which stops the tissues crawling up the ecm.
Though you could assume a large area of fresh ecm (e.g. lets say a patch half the size of an elephants back) could be oxidized (which would denature, perhaps hyaluaric acid would aid here?) slightly more than a smaller area of ecm on a humans back, and the elephant might need a revision may be?
However that Elephants back theory, is not good, be it, as well as coming in from the sides the tissue also grows from underneath the ecm, meaning the central parts of the elephants ecm tissue would regenerate as fast as the sides.
I completely agree with you and I believe that you misinterpreted my post kirk. If one's healing mechanisms are impaired and one scars more easily than others (many acne scar sufferers will attest to their skin being less healthy/ elastic/ etc.), then this indicates that our own personal ECMs are being denatured from within. Think of the mixture of blood and our own personal ecm, if there is anything toxic or out of balance running through our bodies, this will most likely be a factor that plays into denaturing our healing processes. If additional ecm is to be used such a ACell, it is my theory that someone with a less than desirable state of health will denature this pure ecm without any help from an outside variant. As stated, this is theory of course. My goal is to stress health and wellness before attempting to rid yourselves of scarring left over from a previous life.
Also, the addition of hyaluronic acid may be possible only if it does not work to denature the ecm. Has any research been conducted to give us an answer on that? Those two would be a dream combo.
http://www.newscientist.com/article/dn1638...ll-cabinet.html
In my research I came across this website. I was wondering if anyone has heard anything about this - doctors injecting drugs that stimulate your OWN stem cells - would the stem cells recognize your scar tissue as "damaged" and then regenerate it perfectly? If so, this could be AMAZING because the article predicts it will be on the market in 5 - 10 years!
Thoughts?
http://www.newscientist.com/article/dn1638...ll-cabinet.html
In my research I came across this website. I was wondering if anyone has heard anything about this - doctors injecting drugs that stimulate your OWN stem cells - would the stem cells recognize your scar tissue as "damaged" and then regenerate it perfectly? If so, this could be AMAZING because the article predicts it will be on the market in 5 - 10 years!
Thoughts?
i think this is good news, more things out there the better. I think this all goes together just different treatments to get cells to regrow stuff.
does anyone here think that the acell helped it heal a little bit on the bald guys head even tho theres a scar?
i think it made it heal better.
from what i heard, this is a new type of medicine that has just hit the market. its not like its being discover, we've seen it work. now its just time before they can refine it.
its like the ipod, first ipod was a piece of shit but it was pretty fucking amazing during the time, now today theres ipods that have over 80,000 songs.
look at the bottom theres a link on the that will give you info about acell and how it works. its on the main page!!