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[Sticky] Scarless Healing

 
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17
(@diamond9199)

Posted : 06/12/2022 12:44 am

7 hours ago, presn said:

Some more news. A Soy-protein matrix skin scaffold that leaves little to no scaring is going to be released in 6 months. I have asked the CEO and he confirmed. Here is the link to the product.  https://www.neuesse.com/skin-conditions/post-laser-ablation-skin-resurfacing/

Also here is a description of the product: 

OmegaSkin has been proven to heal full thickness wounds with minimal to no scarring. Further in a patient™s favor is the healed wound will have fully functioning hair follicles and sweat glands. Thus OmegaSkin œHeals like the Skin You™re in.

We have a robust pipeline of products which includes liquid sprayable skin and a proprietary handheld electrospinner for delivery. NeuEsse is developing the portable spinner to deliver other products for aging and traumatized skin such as wrinkle and rejuvenation compounds and will be prominent in Dermatology. The application device is designed to reduce application pain in wound patients where direct manual treatments can be painful. 

Our OmegaSkin„ will provide off-the-shelf solutions in pre-manufactured sheets and a handheld portable device for no-touch applications of our Liquid Skin and other commercial therapeutics.

thumbnail_image0.jpg

and when it comes to the market?

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(@isadora-scatena)

Posted : 06/13/2022 12:30 am

I already mentioned it. 6 months from now @Diamond9199. Considering they are partnered with CMU (one of the top universities in the U.S. https://engineering.cmu.edu/pita/projects/public-health-medicine/2020/soy-protein-based-campbell.html ) they are probably telling the truth.

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(@isadora-scatena)

Posted : 06/13/2022 7:06 pm

On 2/15/2022 at 6:43 AM, lehran said:

Been a long time since I came here fellas:

About Elastagen: the reason you're not hearing about anything is because of a NDA. Elastagen was first acquired by Allergan (a big pharmaceutical company) which was afterwards acquired by Abbvie (one of the biggest pharmaceutical companies in the world)...sooooo basically yes, it is in the pipeline obviously, they're working on it in their labs, but you're not going to hear about anything regarding it until Abbvie chooses to do so.

It's good news...but it's frustrating: it's good in the sense that it's really going to happen, but it's frustrating in the sense that we have very little ways to find out anything else about it.

Here is proof that Elastagen is in the pipeline. Allergan filed this patent on the use of Tropoelastin for acne scars. This also has the results of the study conducted in depth! There are even more patents on Tropoelastin from Allergan you just have to look them up.

https://patents.google.com/patent/WO2021037733A1/en

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(@isadora-scatena)

Posted : 06/17/2022 10:43 pm

Here is another scarless hydrogel company that is really promising coming from the University of Toronto. Unlike Sunogel, they have been giving frequent updates (last one is may 2022) and have investment from TWO major firms. In a 2020 interview, they claimed that it will be available for surgical use in 2-3 YEARS (The pandemic likely slowed this down a bit; although they just have been designated as a type VI medical device in Canada). This one is legit and likely coming very soon. I will keep you updated when the company representative responds to an email with questions. 

http://quthero.com/

Screenshot 2022-06-17 204439.png

"About Quthero:
Quthero aims to disrupt skin care following dermatological procedures such as laser skin resurfacing & microneedling and to eliminate scarring post plastic surgery using patented hydrogels. Quthero™s flagship hydrogel product enables full regrowth of human skin 60-200% faster than current products and without scarring. At the heart of all Quthero™s products is a unique peptide sequence, discovered and developed at MIT, Boston Children™s Hospital and University of Toronto, that is demonstrated to promote full and scarless skin regeneration. This unique molecule is incorporated into three new products launched
through Quthero Skincare, targeting cosmetic dermatology"

 

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151
(@candy-says)

Posted : 06/18/2022 9:12 am

@presn I am here to appreciate your contribution to this thread. Very interesting stuff.

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(@ecek)

Posted : 06/18/2022 6:42 pm

if elastagen is on the pipeline, how long does it take to come out ? any ideas ?

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(@optimistnocebo)

Posted : 06/19/2022 9:07 am

Is it normal for scars to look worse than pre-treatment after Infini RF? Had it done last week but my scars look worse than they did before I had infini RF done.

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(@isadora-scatena)

Posted : 06/19/2022 6:04 pm

@Candy SaysBtw I contacted the founder of Sunogel and he said that the pandemic caused some delays but he is still working on the product at the moment but hasn't updated the website. This is further supported by the patents that he has recently filed. 

Screenshot 2022-06-19 160250.png

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(@isadora-scatena)

Posted : 06/20/2022 10:45 pm

@Candy SaysThis is the email response for Quthero. Great News!!!! (Even though they haven't tested on old scars it should work in theory with scar revision)

Hi,
Thanks. We are not sure if it would work on old scars. We only tested on fresh incisions, ie scar prevention. The derm gel should be available later in the Fall through doctors offices. We could also sell directly at that time.
Thanks,
Milica

Again this fall!!! This might all be over soon!

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17
(@diamond9199)

Posted : 06/25/2022 7:04 am

Does anyone have any news about elastagen?

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97
(@lehran)

Posted : 06/25/2022 4:58 pm

Some news guys (although @presnalready mentioned something similar before) :

https://www.abbvie.com/our-science/pipeline/devices.html

Tropoelastin, the elastagen-made product, is OFFICIALLY in the pipeline (we couldn't see it before). Which means the trials were successful and it does work the way it was intended to: correcting atrophic scars and stretch marks.

Doesn't sound like much when you say it like that, but it's very VERY big: we've been waiting for years for this to happen. First Allergan bought Elastagen, then Abbvie (one of the biggest pharmaceutical companies in the world, mind you) bout Allergan.

So now, it's just a matter of time, but it's gonna happen.

TLDR: it's super big news regarding people with stretch marks and atrophic scars. Just gotta be patient now, we know there's a breakthrough and that it works. Abbvie will VERY probably post official news in the foreseeable future at that point, let's wait.

For hypertrophic scars, there's still a long way to go though (as far as tropoelastin is concerned) so you might want to look at other trials from other labs in the meantime (and to be honest, I'm not familiar at all with hypertrophic scars since that's not what got me on this journey)

Take care y'all.

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41
(@skin-pessimist)

Posted : 06/26/2022 1:04 pm

20 hours ago, lehran said:

Some news guys (although @presnalready mentioned something similar before) :

https://www.abbvie.com/our-science/pipeline/devices.html

Tropoelastin, the elastagen-made product, is OFFICIALLY in the pipeline (we couldn't see it before). Which means the trials were successful and it does work the way it was intended to: correcting atrophic scars and stretch marks.

Doesn't sound like much when you say it like that, but it's very VERY big: we've been waiting for years for this to happen. First Allergan bought Elastagen, then Abbvie (one of the biggest pharmaceutical companies in the world, mind you) bout Allergan.

So now, it's just a matter of time, but it's gonna happen.

TLDR: it's super big news regarding people with stretch marks and atrophic scars. Just gotta be patient now, we know there's a breakthrough and that it works. Abbvie will VERY probably post official news in the foreseeable future at that point, let's wait.

For hypertrophic scars, there's still a long way to go though (as far as tropoelastin is concerned) so you might want to look at other trials from other labs in the meantime (and to be honest, I'm not familiar at all with hypertrophic scars since that's not what got me on this journey)

Take care y'all.

Great news. Thanks for the update

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41
(@skin-pessimist)

Posted : 06/26/2022 1:42 pm

I'm going to go about things as if I won't have access to tropoelastin, since we don't know how much it will cost or when it will hit the market. But the developments lately are certainly optimistic

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80
(@sniffy)

Posted : 06/28/2022 3:59 am

We will hopefully see verteporfin start being tested on humans soon. Optimization may be the key.

 

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101
(@slave-of-jesus)

Posted : 07/02/2022 11:58 am

On 6/25/2022 at 11:58 PM, lehran said:

 

Tropoelastin, the elastagen-made product, is OFFICIALLY in the pipeline (we couldn't see it before). Which means the trials were successful and it does work the way it was intended to: correcting atrophic scars and stretch marks.

 

what does the term scar correction mean?Because personally I don't want a simple improvement but a real healing of the scars.

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410
(@catharsis2018)

Posted : 07/06/2022 5:35 pm

On 7/2/2022 at 12:58 PM, slave of jesus said:

what does the term scar correction mean?Because personally I don't want a simple improvement but a real healing of the scars.

Physiologically, I don't know how scars can be "healed". The reason there are scars in the first place is because of destruction of tissue. They can't just undestruct the tissue...

 

But scar correction? yes. Excision? yes. Strong peels? yes.

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92
(@binga)

Posted : 07/09/2022 1:44 pm

On 6/17/2022 at 8:43 PM, presn said:

Here is another scarless hydrogel company that is really promising coming from the University of Toronto. Unlike Sunogel, they have been giving frequent updates (last one is may 2022) and have investment from TWO major firms. In a 2020 interview, they claimed that it will be available for surgical use in 2-3 YEARS (The pandemic likely slowed this down a bit; although they just have been designated as a type VI medical device in Canada). This one is legit and likely coming very soon. I will keep you updated when the company representative responds to an email with questions. 

http://quthero.com/

Screenshot 2022-06-17 204439.png

"About Quthero:
Quthero aims to disrupt skin care following dermatological procedures such as laser skin resurfacing & microneedling and to eliminate scarring post plastic surgery using patented hydrogels. Quthero™s flagship hydrogel product enables full regrowth of human skin 60-200% faster than current products and without scarring. At the heart of all Quthero™s products is a unique peptide sequence, discovered and developed at MIT, Boston Children™s Hospital and University of Toronto, that is demonstrated to promote full and scarless skin regeneration. This unique molecule is incorporated into three new products launched
through Quthero Skincare, targeting cosmetic dermatology"

 

I would like to apply this hydrogel after micro coring could be a game changer

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0
(@ecek)

Posted : 07/17/2022 1:02 pm

do you guys any idea how long does it take to product come out from the pipeline ? ( asking for elastagen)

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97
(@lehran)

Posted : 07/18/2022 7:24 am

18 hours ago, ecek said:

do you guys any idea how long does it take to product come out from the pipeline ? ( asking for elastagen)

that's a question better asked to abbvie at this point.
What I can tell you is that the ex owners of elastagen are under a NDA so they can't say anything anymore.

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0
(@vasilis9br)

Posted : 07/31/2022 6:51 am

Scarless healing doesnt meen turning scar tissue into normal skin(that will probably never happen) but rather either allowing the skin to heal without forming a scar or removing the old scar and allowing the skin to heal all over without it.

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0
(@dylanlep)

Posted : 08/04/2022 10:37 am

On 6/25/2022 at 2:58 PM, lehran said:

Some news guys (although @presnalready mentioned something similar before) :

https://www.abbvie.com/our-science/pipeline/devices.html

Tropoelastin, the elastagen-made product, is OFFICIALLY in the pipeline (we couldn't see it before). Which means the trials were successful and it does work the way it was intended to: correcting atrophic scars and stretch marks.

Doesn't sound like much when you say it like that, but it's very VERY big: we've been waiting for years for this to happen. First Allergan bought Elastagen, then Abbvie (one of the biggest pharmaceutical companies in the world, mind you) bout Allergan.

So now, it's just a matter of time, but it's gonna happen.

TLDR: it's super big news regarding people with stretch marks and atrophic scars. Just gotta be patient now, we know there's a breakthrough and that it works. Abbvie will VERY probably post official news in the foreseeable future at that point, let's wait.

For hypertrophic scars, there's still a long way to go though (as far as tropoelastin is concerned) so you might want to look at other trials from other labs in the meantime (and to be honest, I'm not familiar at all with hypertrophic scars since that's not what got me on this journey)

Take care y'all.

Do you read anything into the fact they filed for acne scars only and not stretch marks?

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(@chicken1007203)

Posted : 08/12/2022 3:34 pm

Is there before after photos on tropoelastin? How effective is it?

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378
(@rez77)

Posted : 08/18/2022 1:08 am

guys i've been coming here on and off for 15 years and I've been hearing about hydrogels etc.. for ages. All this stuff above are just fillers. It's all still "in the future," "needs more work," blah blah. I don't see how anything here is new. This is as advanced as we have right now and it's definitely at least 20 years away or more for clinical use. Right now they're using rat tail stem cells mixed with human foreskin printing etc. etc. It's not going to be possibility anytime soon. If they can't do it how is guoming sun going to do anythng better.

 

 

 

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378
(@rez77)

Posted : 08/18/2022 1:24 am

the only game in town for a long while is going to be subcision with plenty of fillers (as you pass 40 those atrophic scars start to get way deeper) and then additional textural improvement with rf inini laser/needling. And that's what we got guys. If you're in your teens now maybe in your 30s there will be something. Right now you can get 30 percent improvement with sculptra and laser and add retinoic acid nightly as it will improve skin turnover.

I've been hearing about this guoming sun guy now for ages all these people are just funded researchers as universities. They're going to be working on these projects all their lives, until they're picked up by the next group of scientists or abandoned all together.

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0
(@dylanlep)

Posted : 08/18/2022 8:40 am

7 hours ago, Rez77 said:

guys i've been coming here on and off for 15 years and I've been hearing about hydrogels etc.. for ages. All this stuff above are just fillers. It's all still "in the future," "needs more work," blah blah. I don't see how anything here is new. This is as advanced as we have right now and it's definitely at least 20 years away or more for clinical use. Right now they're using rat tail stem cells mixed with human foreskin printing etc. etc. It's not going to be possibility anytime soon. If they can't do it how is guoming sun going to do anythng better.

 

 

 

Tropoelastin seems right around the corner no? Granted, it will only treat a couple type of scars - looks like acne and stretch marks. Fully scarless for hypertrophic seems further out, yes.

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