Acne.org Products
3 hours ago, Violet_daisy said:I dont think fda will not approve microcoing for scars. To remove, let's say, a stretch mark, they will have to remove the whole area of skin. If they did that,skin appendages will be removed as well and since 100% skin regenration is not happening anytime soon, microcoring and removing the whole scar seems too risky. I think fda may approve it for loose skin of other areas like neck etc.
If only we had something that could heal the skin and regenerate skin appendages, then maybe piece by piece removal of skin and healthy skin withsweat glands and hair follicles taking its place seems approvable. (Please god,give verteporfin strength to regenrate human skin just like it did with mice :'(
But these are just speculation, that too severely underinformed.
Meanwhile, I'm working on my personality,health and skills cuz I'm so done with desperately trying to find a cure. The best cure In the world can't correct my stretch marks. I have them all over my body. I literally need a complete skin transplant lol. The only thing that makes me sad is that I can't wear my favourite kind of clothing (saari, traditional Indian dress) without worring about my stretch marks.
I'm seriously considering never having kids. Jk lol
This platform gives me hope. Knowingthat men are just as insecure about stuff as I am, is so reassuring.
Microcoring hasbeen approved and whilst its only for loose skin atm I have no doubt somewhere some Practitioner/clinic will use it for scars but probably smaller scars to begin with.
Only a few key practitioners are approved to use it atm. 2022 it will go full commercial roll out.
If you have smaller scars and not so spread I think you will potentially benefit more from Microcoring. There are question marks around how much skin can safely be removed especially in younger patients.
We shall see, but unlikely for the remainder of 2021
1 hour ago, Skin Pessimist said:Unfortunately not, and I still think it's incredibly disappointing that he removed all of those pinned guides
What was pinned? Practitioners for Microcoring?
4 hours ago, Sniffy said:Microcoring hasbeen approved and whilst its only for loose skin atm I have no doubt somewhere some Practitioner/clinic will use it for scars but probably smaller scars to begin with.
Microcoring is approved only for lower face as of now. Hopefully they'll get approval for other areas too.
I may be completely wrong but microcoring a large amount of skin without regenration of atleast some part of it sounds so unnatural. Skin is supposed to function properly only with all its appendages intact.I've studied physiology for 2 semesters and I'm no expert but I dont think that we can remove the whole scar without irreversibly damaging and over tightening surrounding skin. I'm hoping that verteporfin works. Because if it does (even with 80% efficiency), then scar removal is possible innear future.
I was going through a thread on lib redd.it and someone commented that they know surgeons in New York who were able to recover 99% of hair follicles for fue hair transplant. If that's true and verteporfin actually works, then I'm very hopeful about future of scar management. I'm keeping my fingers crossed for verteporfin because guys, skin regeneration is not something we can skip if we want >90% improvement andclose to natural skin feel.
people were saying 2022-2023 is when we can expect it and I saw some people in this forum say they are releasing before/after pics at the end of this year. So I think we can expect it around then, at least the injectable for stretch marks/acne scars
On 10/9/2021 at 1:08 AM, Skin Pessimist said:The process will likely take several more years, if not longer. We may get some updates in that time, but this isn't a subject much news is posted on. Many of the updates here are from forum members reaching out
peoplewere saying 2022-2023 is when we can expectit and I saw some people in this forum say they are releasing before/after pics at the end of this year. So I think we can expect it around then, at least the injectable for stretch marks/acne scars
On 3/31/2020 at 4:36 AM, lehran said:I can link you literally all the interesting sources I got about elastagen if you want. I got them all bookmarked, there must be 20 of them or so. There are much more out there obviously but those seemed good to me at the very least.
@ermete55 It's probably going to be better than that, but it's gonna take longer to come out than the product they have for stretch marks and acne scars (AND, like others mentioned, they're still going to need on box scars and ice pick scars)
This is from 2017, before they were bought by Allergan/Abbvie
"The companys first target was the medical-aesthetics market. Daniels thought that, with enough funding, it could develop more than one formulation in a reasonable time frame. The company now has products that target three main indications. The most advanced is an injectable gel that makes stretch marks and acne scars fade away. Another is for surgi-cal scars and will be co-developed with a global medical-devices company that has established marketing and sales channels in numerous countries. The third application is in wound repair"
Can you link me some of the bookmarks and sources you have regarding elastagen? It would be greatly appreciated
9 hours ago, Diamond9199 said:
Verteporfin is being tested for other types of stuff other than scarring due to it being a YAP inhibitor. Interesting stuff for sure. Also,I saw an article where it stated thatVerteporfin market is predictedto have an overwhelming hike in revenues between 2021 and 2027. Only time will tell how effective it will be. It seems like the pig trials are taking forever lmao
2 hours ago, gueste said:Verteporfin is being tested for other types of stuff other than scarring due to it being a YAP inhibitor. Interesting stuff for sure. Also,I saw an article where it stated thatVerteporfin market is predictedto have an overwhelming hike in revenues between 2021 and 2027. Only time will tell how effective it will be. It seems like the pig trials are taking forever lmao
Can you please try and find that article? I'm very interested to see what it says.
https://stanmed.stanford.edu/2021issue2/upfront/prevent-scarring-mice-eye-disease-drug.html
Same old story, just re-published.
I don't see the amount of skin being cored out being a problem, remember that skin is elastic as it stretches and maintains it's shape according to our musculature. This ability decreases with old age but then again microcoring removes redundant skin of that nature so it's a solid win in my book and for my type of scarring.
Can anyone try and find the complete research paper for this?
https://www.sciencedirect.com/science/article/abs/pii/S1534580721007620
Delay your HTs, or get scared for life (Breakthrough!). Transplants
A few months back Stanford researchers broke the internet by releasing a study of the usage of Verteporfin in wounds in mice. As many of you probably already know it produced amazing results. Verteporfin treated mice had virtually no scarring, and hair regrew with blood vessels and glands.
Obviously amazing news. However, mice skin is very different from human skin. So the next step for the Stanford researchers was pig trials. Pig skin is very similar to human skin. And is considered the gold standard of skin models.
What many people dont know, is that the stanford researchers have already succeeded in scarless wound healing in pigs!
This was with another medication called VS-6062, a Focal Adhesion Kinase inhibitor. FAK inhibitors inhibit YAP, which is the target of Verteporfin. In other words FAK inhibitors targets the fibrosis chain one step ahead of Verteporfin.
Wound tissue treated with FAKI exhibited dramatic regrowth of hair follicles and subcutaneous glands (sweat and sebaceous) (Fig. 1h), as well as newly regenerated peri-follicular adipose tissue
This is huge news. Especially for those considering FUTs or FUEs.
Look at the latest Hairlosscure2020 post. The pictures are incredibly impressive!
20 hours ago, Diamond9199 said:
Delay your HTs, or get scared for life (Breakthrough!). Transplants
A few months back Stanford researchers broke the internet by releasing a study of the usage of Verteporfin in wounds in mice. As many of you probably already know it produced amazing results. Verteporfin treated mice had virtually no scarring, and hair regrew with blood vessels and glands.
Obviously amazing news. However, mice skin is very different from human skin. So the next step for the Stanford researchers was pig trials. Pig skin is very similar to human skin. And is considered the gold standard of skin models.
What many people dont know, is that the stanford researchers have already succeeded in scarless wound healing in pigs!
This was with another medication called VS-6062, a Focal Adhesion Kinase inhibitor. FAK inhibitors inhibit YAP, which is the target of Verteporfin. In other words FAK inhibitors targets the fibrosis chain one step ahead of Verteporfin.
Wound tissue treated with FAKI exhibited dramatic regrowth of hair follicles and subcutaneous glands (sweat and sebaceous) (Fig. 1h), as well as newly regenerated peri-follicular adipose tissue
This is huge news. Especially for those considering FUTs or FUEs.
Look at the latest Hairlosscure2020 post. The pictures are incredibly impressive!
My god , our nightmare is almost over , i feel like crying , god thank you !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
20 hours ago, Diamond9199 said:
Delay your HTs, or get scared for life (Breakthrough!). Transplants
A few months back Stanford researchers broke the internet by releasing a study of the usage of Verteporfin in wounds in mice. As many of you probably already know it produced amazing results. Verteporfin treated mice had virtually no scarring, and hair regrew with blood vessels and glands.
Obviously amazing news. However, mice skin is very different from human skin. So the next step for the Stanford researchers was pig trials. Pig skin is very similar to human skin. And is considered the gold standard of skin models.
What many people dont know, is that the stanford researchers have already succeeded in scarless wound healing in pigs!
This was with another medication called VS-6062, a Focal Adhesion Kinase inhibitor. FAK inhibitors inhibit YAP, which is the target of Verteporfin. In other words FAK inhibitors targets the fibrosis chain one step ahead of Verteporfin.
Wound tissue treated with FAKI exhibited dramatic regrowth of hair follicles and subcutaneous glands (sweat and sebaceous) (Fig. 1h), as well as newly regenerated peri-follicular adipose tissue
This is huge news. Especially for those considering FUTs or FUEs.
Look at the latest Hairlosscure2020 post. The pictures are incredibly impressive!
The pig trials with VS-6062 weren't completely scarless right? Or am I wrong? It wasn't complete regenerationbut it was just reduced scarring.
On 10/22/2021 at 5:48 PM, giddy said:We did comment the study of FAKI on pigs amonth or twoago.
What I am curious about, is weather they are doing verteporfin on pigs right now or what. Like why is it taking so long?
Apparently they are/werefinishing up the trials on pigs, who knows how long until they release the results though.
Take a look: (scroll down to where it says verteporfin wound healing update 8/29/21) [Edited link out]
How have we not heard at least one case of tgis being used on someone off label yet?
On a hair loss forum someone mentioned a couple of surgeons in NY were using it on FUE and getting complete regenration of hair follicles. Could be BS who knows
On 10/23/2021 at 6:35 AM, dermaldamage said:Apparently they are/werefinishing up the trials on pigs, who knows how long until they release the results though.
Take a look: (scroll down to where it says verteporfin wound healing update 8/29/21) [Edited link out]
These news came before pig studies with FAKI was published. Was wondering if he meant that study
https://www.instagram.com/p/CVfvpIRlCwd/
microcoring
More info
https://www.instagram.com/p/CR1Y6S8LMsd/
