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7 hours ago, mysharon said:Yeah. Have you seen the before afters of micro-coring for wrinkles? Does it look like scarless or wrinkle free? Iwouldn't say, there is slight improvement but the lady still has wrinkles. For scars it is even more questionable. Maybe in dark skin types, where lasers don't get recommended it could help though. Many sessions.
About Verteporfin absolutely, they are trying to get people scarfree from their cosmetically bothersome surgicalscars, and to prevent scarring of organs,which will be a huge success if they do it. They will be saving lives. That's what all the fuss is about. Maybe, just maybe, the drug could help with better healing after scar treatments if it indeed has such huge regeneration potential, but acne scars are old and often atrophic so people should really stay on the ground here.
Quite frankly i dont even see improv there
3 hours ago, mysharon said:Ablative lasers remove tissue by evaporating it, hence the name ablative.
You seem like someone trying to defend very old technologies that will become obsolete within the cosmetic industry ... lasers also hold alot of risk , scarring being one of them.
3D bioprinting skin has been applied to skin graft and burn scar treatment since this year. It's not something sci-fi technology...
https://www.iha.com.tr/haber-yanik-tedavisinde-dunyada-bir-ilk-turkiyede-uygulaniyor-891254/
https://www.albayan.ae/uae/news/2021-05-28-1.4173790
It would be awesome if it's combined with verteporfin.
4 hours ago, mysharon said:Ablative lasers remove tissue by evaporating it, hence the name ablative.
Dude.. lol. Are you trolling..
Anyways..
I dont know why the hell we are talking about lasers and micro coring, theyre hacks that try to improveskinappearance, theyre not in the category of scarless healing. Ifanything wecan bring up sunogel, and talk about how that was kinda of a failure ergo dont get your hopes aboutverteporfin, as they both try toachieve a similar thing.
Otherwise, everyone relax, things will come when they come, we are not in any position of influence. Live your lives, for anyone whose been here long enough you are well aware of the emotional roller coaster that is scarless healing.
On the bright side with verteporfin, things are actually moving along and it is more in the category of,it will work or it wont work. If verteporfindoesnt work out of the box, forget it, it will take years and years to iron out what the delta is between mice and humans and deliveran altered solution.If it does work and truly offers wound regeneration then theres hope and it wouldnt take long to validate whether it will work for usand will probably be used off label if promisingearly human clinical trials appear. Off label use was not an idea that spawned out of these forums, it was a fear fromlongaker and his team that doctors would used it before proper trials were conducted.
6 hours ago, Scarcure said:You seem like someone trying to defend very old technologies that will become obsolete within the cosmetic industry ... lasers also hold alot of risk , scarring being one of them.
Not defending anything. Just pointing out that what was being stated that micro-coring is the first device to remove tissue is simply not true, as are not true a lot of statements being done on this thread.
Micro-coring isn't without risks either. Otherwise they wouldn't limit the density to 5%.
4 hours ago, Scars4Life said:Dude.. lol. Are you trolling..
Anyways..
I dont know why the hell we are talking about lasers and micro coring, theyre hacks that try to improveskinappearance, theyre not in the category of scarless healing. Ifanything wecan bring up sunogel, and talk about how that was kinda of a failure ergo dont get your hopes aboutverteporfin, as they both try toachieve a similar thing.
Otherwise, everyone relax, things will come when they come, we are not in any position of influence. Live your lives, for anyone whose been here long enough you are well aware of the emotional roller coaster that is scarless healing.
On the bright side with verteporfin, things are actually moving along and it is more in the category of,it will work or it wont work. If verteporfindoesnt work out of the box, forget it, it will take years and years to iron out what the delta is between mice and humans and deliveran altered solution.If it does work and truly offers wound regeneration then theres hope and it wouldnt take long to validate whether it will work for usand will probably be used off label if promisingearly human clinical trials appear. Off label use was not an idea that spawned out of these forums, it was a fear fromlongaker and his team that doctors would used it before proper trials were conducted.
No dude, I am correcting a false statement. If you look at the illustration of Cytrellis, micro-coring practically does the same as laserswithout the heat side effects, they are trying to minimize the side effects, which is great. Rox Anderson also invented the fractional laser technology so the man is a genius but the micro-coring technology seems to be limited to very small density of 5-10%. We will see what the device will be able to do once it becomes more widely available. Hopefully it won't turn out to be the next rejuvenation treatment as it seems at the moment, suitable best to give ageing people a fresher look in a save way.
Micro coring and Laser are very different, lasers use heat whereas Microcoring removes tissue mechanically. Micro coring is much closer to needling. Medical Needling (3mm) has given me pretty good results but it has its limits and when you reach a certain point you need something else. That last 20-30% is the hurdle to high, it is the brick wall we haven't knocked over yet I was once told by a Derm.
Thats why Im interested in Microcoring for its ability to remove tissue without leaving scars. Its still very early days for it remember it was only approved a few weeks ago for skin rejuvenation. Much the same way Lasers were approved first for skin rejuvenation before they were introduced to scar patients.
If it goes deep intothe dermis/sub dermis level and removes that tissue thats pretty easy to comprehend when you pick a small scar on your face and imagine that process numerous times. What has me unsure will be how the skin responds to that and whether it closes up and the area and is then smaller thus a reduced scar or it just re populates with unwanted scar tissue idk...
I think if your scars are very small in diameter you could get the best results if it works at all. Deeper indentations and more widespread may be an enormously long tedius process to get results.
Maybe it will work and has shown towork but the accuracy is an issue when trying to limit the amount of skin removed plus the amount of treatments needed is ridiculous because the core sizes are so miniscule in size thus making it not an appropriate device for acne scars.
Yes its all speculation along with Verteporfin but its exciting and well worth following to see what happens
Micro-coring in terms of mechanism of work is more similar to ablative fractional lasers (both invented by Anderson, both remove skin in columns) without the dreaded energy side effects and with shorter downtime. It has the derm community all excited as it is new, revolutionary and they cansell it as a safe alternative to lasers orfacelift. In my opinion, it won't be able to give dramatic results with the current coverage it uses, rather a fresher younger look for ageing 40 or 50 year olds. There is a lot of demand for this, and the angi-ageing market is actually way bigger than the scar correction market.
Cytrellis are harder to get information out of with regard to scars but they hinted to me they are working on some development devicesin the background and to stay tuned.
Recros medica have a little more info on there site with ambitions to target scars and tattoos but they are lagging behind on the timeline. They believe they can remove tattoos in 4 to 5 treatments and reduce the surface area of scars.
Skin rejuvenation/tightening will always take precedence when it comes towho is first. Everyone gets old so the market is huge, not everyone has scars or tattoos but they are still big markets and usually follow but are also harder to treat historically.
On 7/6/2021 at 7:08 AM, lehran said:Hi guys, I haven't been here for a long time !
Regarding Elastagen: the scientific drafts with before/after pictures regarding the potency of elastagen for fixing stretch marks should be coming out in a few months according to the executives of elastagen (around the end of the year). I'll keep you updated and tell you when it's out, and I'll share photos if I can too obviously.
I think there will ALSO be before/after photos for the treatment of acne scars, so that might interest you guys as well.
Anyways, we shall see.
Any updates ?
On 11/19/2020 at 2:11 PM, lehran said:I actually completely agree with you when you mention different types of scars. I, for example, can't see how a simple injection would address hypertrophic scars, which are very raised, and sometimes super severe.
The main focus of elastagen right now is atrophic scars, as the idea is to repair the dermis and replace the voids left by the damage with a tropoelastin-based IMPLANT (the word implant is important here). It's basically the same idea for stretch marks and acne scars: using a synthetic 3D skin (which is what they created, basically) to cover the damage.
They're really not there yet when it comes to more severe kinds of scaring like hypertrophic scars. If you read some of my older comments (thank you for that btw), you'll find one with tons of links about elastagen. I believe there's one (probably an audio file) where Tony Weiss mentions that they still have a long way to go for more severe scars, and I really doubt that JUST a filler is the solution. It's probably going to be a combination of things.
So no, you're not coming off as confrontational or anything, you actually made very good points.
Ah, also, about the 80-90% improvement, I wrote something about that (concerning the kind of improvement one should expect), as people usually have the wrong idea about what that means, did you find that part?
So would the implant fuse in your body through elastoginisis and regrown the missing things like blood vessels, pigment , hair follicles , etc? Or how will it work. I also wonder if the strike would need to be white and old for this to work or if it also works on striae rubra. There isnt much info about this stuff anywhere. I just hope this can clear stretch marks enough to the point where they arent noticeable
Hey guys, does anyone know any ways to fade red stretch marks? Also any of you guys know whats up with elastagen and if there are gonna be any updates regarding it and how it will be for stretch marks? Thanks in advance
Is anyone willing to buy verteporfin and try it on themselves? I kinda want to but am a afraid it will go very wrong.
https://www.bristol.ac.uk/news/2020/november/scar-free-healing-.html
This was published in November 2020 and they're saying they want to achieve this within a generation.
On 9/23/2021 at 7:55 AM, Guest said:'The Scaar Fx was mentioned in reference to the burn victims, there are many successful stories of burn victims online. The Scaar Fx is not suitable for acne scars.
We will live and see what will happen to Verteporfin andthe other scarless healing treatments in a few years. Hopefully they don't fail miserably as Elastagen and all the previous high hopes.
What do you mean elastagen failed? Arent they releasing their studies this year with pictures of before/after?
18 hours ago, Diamond9199 said:the last article was published almost a year ago. I think there will be news again at the end of the year
Man elastagen has been saying they have breakthrough treatment which is tropelastin for a bunch of problems since 2018.. why they takin so long? You would think they would like to get the product out and start making that $$$. Oh well, hopefully it comes out soon and we can all benefit from their product. And I understand they need to pass clinical safety and efficacy and all the other stuff, but I would imagine their would be some updates at least
7 hours ago, Baller223 said:Man elastagen has been saying they have breakthrough treatment which is tropelastin for a bunch of problems since 2018.. why they takin so long? You would think they would like to get the product out and start making that $$$. Oh well, hopefully it comes out soon and we can all benefit from their product. And I understand they need to pass clinical safety and efficacy and all the other stuff, but I would imagine their would be some updates at least
The process will likely take several more years, if not longer. We may get some updates in that time, but this isn't a subject much news is posted on. Many of the updates here are from forum members reaching out
I dont think fda will not approve microcoing for scars. To remove, let's say, a stretch mark, they will have to remove the whole area of skin. If they did that,skin appendages will be removed as well and since 100% skin regenration is not happening anytime soon, microcoring and removing the whole scar seems too risky. I think fda may approve it for loose skin of other areas like neck etc.
If only we had something that could heal the skin and regenerate skin appendages, then maybe piece by piece removal of skin and healthy skin withsweat glands and hair follicles taking its place seems approvable. (Please god,give verteporfin strength to regenrate human skin just like it did with mice :'(
But these are just speculation, that too severely underinformed.
Meanwhile, I'm working on my personality,health and skills cuz I'm so done with desperately trying to find a cure. The best cure In the world can't correct my stretch marks. I have them all over my body. I literally need a complete skin transplant lol. The only thing that makes me sad is that I can't wear my favourite kind of clothing (saari, traditional Indian dress) without worring about my stretch marks.
I'm seriously considering never having kids. Jk lol
This platform gives me hope. Knowingthat men are just as insecure about stuff as I am, is so reassuring.