5 hours ago, Scars4Life said:Stem cell held a lot of promise some time ago. It may realize a bigger potential some day.
One of the issues for me with scarless healing is discounting it as an engineering problem, and instead having thisstrong reliance on the hypothesis that flipping gene switcheswill achieve the perfect skin. Maybe like any fabric we encounter, once skin is out of the factory all we can do ispatch work, maybe its too big of a problem to solve by trying to play god and findingthe right gene switching sequence.
Now,verteporfin somehow did achieve it with mice, so the hypothesis definitely seems pretty plausiblethat it could work with humans, but it will probablyinvolve more coordination than just verteporfin after seeing the pig results with FAKI.Ill also mention this guy cause I dont think people know him, Michael Levin. I think hes really really ahead of his time and his labmay be able to solve even bigger problems than scarless healing underhis framework.
does the results in pigs were disappointing?
37 minutes ago, De Rerum Natura said:does the results in pigs were disappointing?
The results in pigs with Verteporfin haven't been published yet. However, they used something different that basically does the same thing as verteporfin would.In that study, it showed regeneration but notcomplete regeneration.
12 hours ago, Scars4Life said:Stem cell held a lot of promise some time ago. It may realize a bigger potential some day.
One of the issues for me with scarless healing is discounting it as an engineering problem, and instead having thisstrong reliance on the hypothesis that flipping gene switcheswill achieve the perfect skin. Maybe like any fabric we encounter, once skin is out of the factory all we can do ispatch work, maybe its too big of a problem to solve by trying to play god and findingthe right gene switching sequence.
Now,verteporfin somehow did achieve it with mice, so the hypothesis definitely seems pretty plausiblethat it could work with humans, but it will probablyinvolve more coordination than just verteporfin after seeing the pig results with FAKI.Ill also mention this guy cause I dont think people know him, Michael Levin. I think hes really really ahead of his time and his labmay be able to solve even bigger problems than scarless healing underhis framework.
Well maybe a combination of therapies , gene switching , light therapy , stem cells , but it's there and will happen.
6 hours ago, gueste said:The results in pigs with Verteporfin haven't been published yet. However, they used something different that basically does the same thing as verteporfin would.In that study, it showed regeneration but notcomplete regeneration.
FAKI reducesYAP, it does notblock it completely. Verteporfin blocks YAP which blocks En1 which blocks scarring in mice. We willse in pigs
On 11/17/2021 at 9:18 PM, Scars4Life said:
Ill also mention this guy cause I dont think people know him, Michael Levin. I think hes really really ahead of his time and his labmay be able to solve even bigger problems than scarless healing underhis framework.
I've heard of him but he seems more focused on xenobots lately. I don't see how xenobots will lead to regeneration in the near future unfortunately.
29 minutes ago, can i get a new life please said:Is recell legit or scam
legitimate, it will help skin, but simply like other procedures. There's nothing rn that can truly fix our skin like it was before puberty yk?
All we can do is wait like retards
This website tells you who in your area offers microcoring: https://www.ellacor.com
why there is no information about verteporfin
4 hours ago, Diamond9199 said:why there is no information about verteporfin
Its frustrating, but a pig study will come in the next months.
Sanofi to acquire Origimm Biotechnology to develop acne vaccine
https://www.europeanpharmaceuticalreview.com/news/166013/sanofi-to-acquire-origimm-biotechnology-to-develop-acne-vaccine/
9 hours ago, Diamond9199 said:Sanofi to acquire Origimm Biotechnology to develop acne vaccine
https://www.europeanpharmaceuticalreview.com/news/166013/sanofi-to-acquire-origimm-biotechnology-to-develop-acne-vaccine/
Now an regeneration vaccine would be even better.
11 hours ago, NagarNikku_ said:Vaccine wouldn't make sense lol, it would have to be some sort of procedure.
Maybe , you're right you'd of have to make an incision to the tissue , but there could be such advancements in medical science where vaccines could be possible
2 hours ago, Scarcure said:Maybe , you're right you'd of have to make an incision to the tissue , but there could be such advancements in medical science where vaccines could be possible
A vaccine healing already occured scar isn't going to be possible at all lol.
You would have to excise the tissue and create an environment suitable for scarless healing (something like a jell-o kind of that a fetus has.)
Or turn off the gene that detects mechanical stress in skin, so that regeneration takes place which would be a slower process than regular healing but would restore normal skin entirely.
Someone emailed Dr. Chen who is the co-author of the verteporfin study and lead author of the faki + hydrogel study!
So this confirms that excision + verteporfin should work right? Since the excision line is thin, it doesn't matter if hair/gland reconstruction isn't 100% in the newly formed tissue -- as long as it *looks* like the unwounded skin (which Dr. Chen says it will), then we're golden.
If this works, subcision + excision should be enough to get rid of scars!!!
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