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[Sticky] Scarless Healing

 
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116
(@niketgandhir)

Posted : 08/25/2021 5:24 pm

11 minutes ago, nikkigirl said:

This thread has been going on for years without nothing really new that actually works for scars. The original poster prolly isn't even around anymore!

Nothing so far, sure. Nothing in the near future either. But it doesn't mean scars will remain untreated forever.

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18
(@tom_mason)

Posted : 08/25/2021 9:56 pm

4 hours ago, nikkigirl said:

This thread has been going on for years without nothing really new that actually works for scars. The original poster prolly isn't even around anymore!

I still check in once in a while.

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Nikkigirl, Scarfreelap, Lapis lazuli and 6 people reacted
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17
(@diamond9199)

Posted : 08/26/2021 3:52 am

10 hours ago, nikkigirl said:

This thread has been going on for years without nothing really new that actually works for scars. The original poster prolly isn't even around anymore!

if you dont believe it, why are you still here?

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657
(@miro)

Posted : 08/26/2021 6:20 am

2 hours ago, Diamond9199 said:

if you dont believe it, why are you still here?

Hope , despite desbelief

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101
(@slave-of-jesus)

Posted : 08/26/2021 8:49 am

science has made very good progress on how healing works. it will not be surprising if we have a treatment for complete skin regeneration in the near future. be positive!

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NagarNikku_, Shelly399, Scarcure and 6 people reacted
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657
(@miro)

Posted : 08/26/2021 10:00 am

1 hour ago, slave of jesus said:

science has made very good progress on how healing works. it will not be surprising if we have a treatment for complete skin regeneration in the near future. be positive!

Near future ? I dont think so , but we ll get there , one day

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116
(@niketgandhir)

Posted : 08/26/2021 11:59 am

1 hour ago, Miro said:

Near future ? I dont think so , but we ll get there , one day

What do you think about this decade?

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116
(@niketgandhir)

Posted : 08/26/2021 12:15 pm

https://link.springer.com/article/10.1007/s00441-021-03505-9

Can anyone help get the complete research paper?

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MemberMember
657
(@miro)

Posted : 08/26/2021 6:20 pm

6 hours ago, NagarNikku_ said:

What do you think about this decade?

Lets pray , but i doubt it , i think 30-40 years

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41
(@gueste)

Posted : 08/27/2021 2:47 pm

So was sunogel just a sham? I've been reading the forum and seen that Dr.Sun claimed to have full regenerationin pigs and mice.He even had photo evidence right?However, there has never been any news on human trials. Is anyone in contact with him anymore? Also, wouldn't his hydrogel be making news everywhere if it did produce full regeneration as we've seen with verteporfin.Sunogel seemed to be a big achievement with no news coverage at all. Quite disappointing.

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17
(@diamond9199)

Posted : 08/27/2021 3:27 pm

When will verteporfin be tested in children? It is written on the Internet that it will be until the end of 2021. I wonder how children's lips are treated with this drug? Or do they apply this drug to children lips after surgery?

44 minutes ago, gueste said:

So was sunogel just a sham? I've been reading the forum and seen that Dr.Sun claimed to have full regenerationin pigs and mice.He even had photo evidence right?However, there has never been any news on human trials. Is anyone in contact with him anymore? Also, wouldn't his hydrogel be making news everywhere if it did produce full regeneration as we've seen with verteporfin.Sunogel seemed to be a big achievement with no news coverage at all. Quite disappointing.

I wrote to him today. well, he hasnt answered yet

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101
(@slave-of-jesus)

Posted : 08/27/2021 4:34 pm

22 hours ago, Miro said:

Lets pray , but i doubt it , i think 30-40 years

so you'd better come back here in 30 or 40 years, otherwise you'll suffer while waiting for a treatment. For me, I think it will be soon, this is my opinion of course, but if I come here it's because I'm optimistic given the recent discoveries

1 hour ago, gueste said:

So was sunogel just a sham? I've been reading the forum and seen that Dr.Sun claimed to have full regenerationin pigs and mice.He even had photo evidence right?However, there has never been any news on human trials. Is anyone in contact with him anymore? Also, wouldn't his hydrogel be making news everywhere if it did produce full regeneration as we've seen with verteporfin.Sunogel seemed to be a big achievement with no news coverage at all. Quite disappointing.

sunogel is not a sham, it is that with the epidemic crisis it has delayed the events.

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657
(@miro)

Posted : 08/27/2021 9:07 pm

4 hours ago, slave of jesus said:

so you'd better come back here in 30 or 40 years, otherwise you'll suffer while waiting for a treatment. For me, I think it will be soon, this is my opinion of course, but if I come here it's because I'm optimistic given the recent discoveries

sunogel is not a sham, it is that with the epidemic crisis it has delayed the events.

I d better come here whenewer i want , yes lets stay optimistic , optimism and hope is eternal on this forum

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(@ivvan)

Posted : 08/27/2021 11:32 pm

Of course we should stay optimistic no matter what, what else can we do, get depressed and kill ourselves? Science is increasing exponentially, we know more about skin and scars than ever, there is a hope, a cure will come, and after it comes it will get better and better.

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17
(@diamond9199)

Posted : 08/28/2021 4:11 am

Guoming Song answered me. he said the sunogel had been postponed due to the pandemic. but he hopes that everything will be fine soon

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116
(@niketgandhir)

Posted : 08/28/2021 4:31 am

19 minutes ago, Diamond9199 said:

Guoming Song answered me. he said the sunogel had been postponed due to the pandemic. but he hopes that everything will be fine soon

Fucks sake.

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28
(@giddy)

Posted : 08/28/2021 4:47 am

What I find strange is Longaker said in the NyTimes article that they already had tested it on pigs and it caused dramatically less scarring. But he also says in other interviewsthat they moved on to the pigs, which will take 3-4 months. So what is the difference betweenthe first test that caused less scarring and what they are testing now?

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28
(@giddy)

Posted : 08/28/2021 5:11 am

Also, why would Lonaker suggest they might have a cure toscarringinNyTimes if he knew Verteporfin did not provide full regeneration in pigs?

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Scarfreelap, slave of jesus, Scarfreelap and 3 people reacted
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657
(@miro)

Posted : 08/28/2021 6:37 am

7 hours ago, Ivvan said:

Of course we should stay optimistic no matter what, what else can we do, get depressed and kill ourselves? Science is increasing exponentially, we know more about skin and scars than ever, there is a hope, a cure will come, and after it comes it will get better and better.

Lets stay realistic, no one should kill himself due to anything

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116
(@niketgandhir)

Posted : 08/28/2021 7:47 am

2 hours ago, giddy said:

What I find strange is Longaker said in the NyTimes article that they already had tested it on pigs and it caused dramatically less scarring. But he also says in other interviewsthat they moved on to the pigs, which will take 3-4 months. So what is the difference betweenthe first test that caused less scarring and what they are testing now?

They're probably trying to obtain complete regeneration in pigs. Maybe they need different dosage size etc.

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28
(@giddy)

Posted : 08/28/2021 9:07 am

1 hour ago, NagarNikku_ said:

They're probably trying to obtain complete regeneration in pigs. Maybe they need different dosage size etc.

Yeah, I hope we will get som news by the end of september!

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Scarfreelap, Shelly399, NagarNikku_ and 9 people reacted
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116
(@niketgandhir)

Posted : 08/28/2021 6:18 pm

New article published by Michael Longaker regarding skin scarring.

https://onlinelibrary.wiley.com/doi/abs/10.1002/med.21853

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7
(@violet_daisy)

Posted : 08/28/2021 9:19 pm

16 hours ago, giddy said:

What I find strange is Longaker said in the NyTimes article that they already had tested it on pigs and it caused dramatically less scarring. But he also says in other interviewsthat they moved on to the pigs, which will take 3-4 months. So what is the difference betweenthe first test that caused less scarring and what they are testing now?

I think that was a 2011 or 2015 study. The same team made a bandage to reduce tension and found that rodents have no scarring and pigs have "much less scarring" or "six times less scarring".

They haven't released the effect of verteporfin yet. Since its a drug that blocks the signalling altogether, that's why scientists are very hopeful that this will be it. I read an interview of another researcher who thinks that this discovery is huge.

Im not losing hope no matter what...

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116
(@niketgandhir)

Posted : 08/29/2021 9:45 am

This is a research paper published by some chinese authors in July.

It covers everything regarding skin scarring, everything researchers know by far. YAP inhibition, mechanotransduction, WNT inhibition.

I honestly believe there are multiple pathways to achieve scarless regeneration.

https://www.mdpi.com/2218-273X/11/8/1095/htm

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David4bay, Shelly399, slave of jesus and 6 people reacted
MemberMember
657
(@miro)

Posted : 08/29/2021 3:03 pm

17 hours ago, Violet_daisy said:

I think that was a 2011 or 2015 study. The same team made a bandage to reduce tension and found that rodents have no scarring and pigs have "much less scarring" or "six times less scarring".

They haven't released the effect of verteporfin yet. Since its a drug that blocks the signalling altogether, that's why scientists are very hopeful that this will be it. I read an interview of another researcher who thinks that this discovery is huge.

Im not losing hope no matter what...

can please someone explain how this is supposed to help people with acne scarring ?

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