https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328485/ It seems clinical results for Vertaporfin/PDT post wounding on established Keloid and Hypertrophic scars are also encouraging.

This study goes back to 2020. It will be very interesting to see how Longakers' experiment with cutaneous scarring in pigs pans outs. If that goes well, I might try to use Verteporfinoff label for a scar revision. Hopefully hear something by end of the year.

On 6/5/2021 at 7:32 PM, Scars4Life said:

Yeah I was reading more and more about this stuff. Havent had time to post anything, but it is seriously frustrating to see the lack of coverage and enthusiasm.

The discovery that Longaker and his team made really wasnt about verteporfin, it was aboutYAP and Engrailed-1, andtheres papers dating back a few years. From what I remember they already had mice that were bred with inhibited YAP and produced regeneration, the trick was finding a wayto deliver those results to a normal mouse.
Verteporfin was just one drug they chose to validatetheir findings, thats the accident portion of the story, they couldve went with any other drug. Nowit looks like theyre validating that just about any drug with those inhibiting propertieswill do.

The point is this is like stupid mind-blowingnews regarding mammalianregeneration. But.. nobody cares.

Waiting for pig results.

Frankly , i still dontunderstand how this is gonnahelp acne scars , but letswait and see , we cant do anything else can we ?

3 hours ago, Miro said:

Frankly , i still dontunderstand how this is gonnahelp acne scars , but letswait and see , we cant do anything else can we ?

I think we can see results on pigs at the end of the summer.

how can we find this drug and try it on ourselves

1 hour ago, Diamond9199 said:

I think we can see results on pigs at the end of the summer.

how can we find this drug and try it on ourselves

Summer of what year ?

26 minutes ago, Miro said:

Summer of what year ?

This year

verteporfin where can we buy this drug?v

On 2/23/2021 at 4:43 PM, David4bay said:

There will be a conference around April on the effectiveness of microcoring as a rejuvenation device. Also, though not cytrellis but fig 131 on recrossmedia device is about using microcoring to remove scars, they have over 7 examples on both using microcoring for w plasty, z plasty and using it only to remove a hypotrophic scar and raise the scar edge to the level of normal skin with continuing treatments to remove the scar. Cytrellis patent mentions it being used to remove scars from acne, accident, etc so the two aren't far off, it's even in the patent that being such an outpatient procedure it could be done in a spa, so if it's released and becomes mainstream it doesn't stop you from going to get it done on your scar even if it's mostly used for skin tightening elsewhere. Best of luck to everyone, hope it all works out well, won't be devastated if it doesn't.

Does anyone know if there are any updates on this conference? 

Not too spectacular but be rest assured people see the potential in regenerative medicine.

1 hour ago, David4bay said:

Not too spectacular but be rest assured people see the potential in regenerative medicine.

 

Yes we all do , but what we want here is at least 20 years away from now , and im very optimistic with 20 years

elastagen doesn't make any news either.is there any hope from elastagen?

None of these upcoming products have givenany updates

22 hours ago, Diamond9199 said:

elastagen doesn't make any news either.is there any hope from elastagen?

There s always hope, may the force be with you

Any news on Verteporfin?

On 6/5/2021 at 7:32 PM, Scars4Life said:

Yeah I was reading more and more about this stuff. Havent had time to post anything, but it is seriously frustrating to see the lack of coverage and enthusiasm.

The discovery that Longaker and his team made really wasnt about verteporfin, it was aboutYAP and Engrailed-1, andtheres papers dating back a few years. From what I remember they already had mice that were bred with inhibited YAP and produced regeneration, the trick was finding a wayto deliver those results to a normal mouse.
Verteporfin was just one drug they chose to validatetheir findings, thats the accident portion of the story, they couldve went with any other drug. Nowit looks like theyre validating that just about any drug with those inhibiting propertieswill do.

The point is this is like stupid mind-blowingnews regarding mammalianregeneration. But.. nobody cares.

Waiting for pig results.

Have you seen any news on this lately?

Hi guys, I haven't been here for a long time !

Regarding Elastagen: the scientific drafts with before/after pictures regarding the potency of elastagen for fixing stretch marks should be coming out in a few months according to the executives of elastagen (around the end of the year). I'll keep you updated and tell you when it's out, and I'll share photos if I can too obviously.

I think there will ALSO be before/after photos for the treatment of acne scars, so that might interest you guys as well.

Anyways, we shall see.

12k replies since 2007 and the reality is we are no closer to finding a successful treatment for acne scarring. See you in another 14 years.

10 hours ago, ScarRight said:

12k replies since 2007 and the reality is we are no closer to finding a successful treatment for acne scarring. See you in another 14 years.

this is your opinion

25 minutes ago, Diamond9199 said:

this is your opinion

Well please enlighten me on some new treatments. The only progress in scar revision since mid 2000s is longer lasting fillers like Bellafill (which can be risky) and some updated models on laser and Infini RF machines. What else has come to market?

2 hours ago, ScarRight said:

Well please enlighten me on some new treatments. The only progress in scar revision since mid 2000s is longer lasting fillers like Bellafill (which can be risky) and some updated models on laser and Infini RF machines. What else has come to market?

you dont replace the current evolution with development 20 years ago.Many things will depend on a persons intention.

2 hours ago, Diamond9199 said:

you dont replace the current evolution with development 20 years ago.Many things will depend on a persons intention.

So what you're basically saying is these treatments and therapies discussed in this 14 year old thread are at least 20 years away...if we are lucky. Got it.

On 7/7/2021 at 12:10 AM, ScarRight said:

12k replies since 2007 and the reality is we are no closer to finding a successful treatment for acne scarring. See you in another 14 years.

Rome was not built in a month. Also we've told you guys tons of times: try to accept yourselves the way you are, don't waste your life being super insecure about stuff like scars, stretch marks, acne yada yada yada. No one's perfect, and no girl or guy (except idiots) will reject you because of that alone.

I'll be happy to get rid of my own skin problems (stretch marks, although they're normal, nothing really severe), but I don't let them ruin my personal life.

Interesting article

https://www.clinicaltrialsarena.com/news/pharmaxis-to-start-world-first-trial-of-scar-reducing-wound-treatment/

6 hours ago, ParisN said:

Interesting article

https://www.clinicaltrialsarena.com/news/pharmaxis-to-start-world-first-trial-of-scar-reducing-wound-treatment/

At least verteporfin is already available. This could be another long wait if it even works

18 hours ago, ParisN said:

Interesting article

https://www.clinicaltrialsarena.com/news/pharmaxis-to-start-world-first-trial-of-scar-reducing-wound-treatment/

Wouls you have to make an excision or incision and apply the cream or just apply the cream on the scar tissue ?

10 hours ago, Scarcure said:

Wouls you have to make an excision or incision and apply the cream or just apply the cream on the scar tissue ?

Have to make an incision same as Verteporfin, scar tissue would need to be removed.