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38 minutes ago, F1racer said:I know it sucks,but, things seem to moving at a quicker pace than 4/5 years ago.
I have a good feeling about micro-coringreplacing a lot of the functions/ improving on the functions of laser/ surgical excision. It might not be an immediate magic solution but I think it will give people a lot of hope. It's a Rox Anderson/ MGH inventionand they've got a proven track record of their ideas gettingto market. Cryolipolysis being one of the most recent ones.
"Dr. Anderson, recognized for his research, has advanced the basic knowledge of human skin photobiology, drug photosensitization mechanisms, tissue optics and laser-tissue interactions. He conceived and developed many of the non-scarring laser treatments now widely used in medical care. These include treatments for birthmarks, microvascular and pigmented lesions, tattoos and permanent hair removal.Notably, Dr. Anderson coinvented the fractional laser treatment, which is useful for improving burn scars, and recently invented and developed new devices for wound grafting without scarring."
I think they said they'd sent the final application off to the FDA in October 2020. On the FDA website they said verdicts can take 8 months. So we'll know by summerif they were successful or failed.
I agree , Hope is important 🙂
21 hours ago, David4bay said:Getting rid of the damaged tissue altogether has always been the best treatment, only thing was another scar resulted from excisions, now you don't get a replacement scar, just neighbouring healthy skin filling the gaps.
The one thing which I have been wondering is that the surrounding skin within a scar tissue is scar tissue, so logically I'm guessing it would need to start from the borders...do you see what I mean? I am not sure how the surrounding scar tissue will respond...If the so called "deletion" event occurs then we would be sorted!
Scar contraction is caused by granulation bed fibroblasts, microcoring doesn't trigger such a response so i doubt you'd have to be picky about where to start from, the little reference on scars said fibrosis(scar tissue) was reduced with each treatment. Fingers crossed we see it this way when its discussed for rejuvenation a few months from now.
More news about elastagen: proper pictures showing before/after comparisons (for stretch marks) will be published in the second half of 2021. Hang in there guys.
I cant believe this thread is still alive..
Well actually I cant believe I even remember the password to this account.
Im an old timer,used to be a somewhat prominent figure here back in 09-10, while still in college.Here Ive found a herd that I couldroam with thatcomprised of like minded people, at a timewhen my day to day life constantly reminded me of my status as ablack sheep.
Long time has passed since and Ive abandoned the search for a cure.There are people in much worse situations and othersin much better. Make an effort to putyourself out there and like minded people will gravitate to you and you to them, and you can have a very fulfilling life. If youre in your 20s, dont miss out on these times, once you get older youll acquire a lot of wisdom and along with it, regrets.
Check back every now and then, but obsessing over these cures..it becomes a never ending cycle.
Now on a side note, Ive briefly skimmed the latest stuff that you guys are getting excited about, just thought Id rant about it for a sec.
Elastagen, and Micro coring.
For Elastagen, just because Allargen is willing to pay an absurd amount for it,does not automatically imply a directcorrelationto itsefficacy. They are a leader in the space of fillers, if theres a another filler that they believe could even become 2nd rank to them, theyll buy them out, no reason to take chances to wait and see if it actually works or not. Second, this is nowhere near scarless healing, its still a filler,hopefully it integrates with your skin generates elastin toimproveappearance and giveextra elasticity.. all good things, can potentially do a lot for rolling scars or stretch marks, but thats about it,truly atrophic stuff, you would need a lot more, would definitely probably need subcision in conjunction and maybe other stuff if you want to truly see something.
Micro coring.. its an interesting one.. if it truly does what I think it says, removing cores at a diameter at which the holes will just close themselves. I think its true for healthy tissue to contract itself to fill thegap that was extracted.I dont know that scar tissue behaves the same way.. but if it does, then yes in theory you can just repeatedly extract skin, until most of the scar tissue has been excised, if it supposedly removes 5% of surface area at a time.. youre looking at a lot of treatments. Now if its through out yourface.. how much of your skin is a safe amount to be extracting. Following this therell be a lot of stretched skin. I dont see this being viable for large areas, since the real issue is not being tackled, this is just a fancy excision, which could be great for a couple scars here and there though.
A contradictorythingIve read somewhereis that the core extracted is actually regenerated by the body with healthy tissue.. which would be really interesting. Ill try to read more about this.
PS.. what the hell happened to the holy grail hydrogel that everyone was talking aboutfor the past few years. Dr Sun just thought he had something but actually didnt?
There was also something calledFS2..
Anyways, stay safe guys!
11 minutes ago, Scars4Life said:I cant believe this thread is still alive..
Well actually I cant believe I even remember the password to this account.
Im an old timer,used to be a somewhat prominent figure here back in 09-10, while still in college.Here Ive found a herd that I couldroam with thatcomprised of like minded people, at a timewhen my day to day life constantly reminded me of my status as ablack sheep.
Long time has passed since and Ive abandoned the search for a cure.There are people in much worse situations and othersin much better. Make an effort to putyourself out there and like minded people will gravitate to you and you to them, and you can have a very fulfilling life. If youre in your 20s, dont miss out on these times, once you get older youll acquire a lot of wisdom and along with it, regrets.
Check back every now and then, but obsessing over these cures..it becomes a never ending cycle.
Now on a side note, Ive briefly skimmed the latest stuff that you guys are getting excited about, just thought Id rant about it for a sec.
Elastagen, and Micro coring.
For Elastagen, just because Allargen is willing to pay an absurd amount for it,does not automatically imply a directcorrelationto itsefficacy. They are a leader in the space of fillers, if theres a another filler that they believe could even become 2nd rank to them, theyll buy them out, no reason to take chances to wait and see if it actually works or not. Second, this is nowhere near scarless healing, its still a filler,hopefully it integrates with your skin generates elastin toimproveappearance and giveextra elasticity.. all good things, can potentially do a lot for rolling scars or stretch marks, but thats about it,truly atrophic stuff, you would need a lot more, would definitely probably need subcision in conjunction and maybe other stuff if you want to truly see something.
Micro coring.. its an interesting one.. if it truly does what I think it says, removing cores at a diameter at which the holes will just close themselves. I think its true for healthy tissue to contract itself to fill thegap that was extracted.I dont know that scar tissue behaves the same way.. but if it does, then yes in theory you can just repeatedly extract skin, until most of the scar tissue has been excised, if it supposedly removes 5% of surface area at a time.. youre looking at a lot of treatments. Now if its through out yourface.. how much of your skin is a safe amount to be extracting. Following this therell be a lot of stretched skin. I dont see this being viable for large areas, since the real issue is not being tackled, this is just a fancy excision, which could be great for a couple scars here and there though.
A contradictorythingIve read somewhereis that the core extracted is actually regenerated by the body with healthy tissue.. which would be really interesting. Ill try to read more about this.
PS.. what the hell happened to the holy grail hydrogel that everyone was talking aboutfor the past few years. Dr Sun just thought he had something but actually didnt?
There was also something calledFS2..
Anyways, stay safe guys!
John Goldenmouth spoken , absolutly agree
FS2! I forgot they existed haha.They released some data from a trial on mature keloidslast month. It showed statistically significant improvement in old keloid scars compared to other products. They are heading in to a stage III trial for old scars potentially by end of 2021.
The are supposedly currently recruiting for FS2 as scar prevention method in a phase II trial.
7 hours ago, Scars4Life said:I cant believe this thread is still alive..
Well actually I cant believe I even remember the password to this account.
Im an old timer,used to be a somewhat prominent figure here back in 09-10, while still in college.Here Ive found a herd that I couldroam with thatcomprised of like minded people, at a timewhen my day to day life constantly reminded me of my status as ablack sheep.
Long time has passed since and Ive abandoned the search for a cure.There are people in much worse situations and othersin much better. Make an effort to putyourself out there and like minded people will gravitate to you and you to them, and you can have a very fulfilling life. If youre in your 20s, dont miss out on these times, once you get older youll acquire a lot of wisdom and along with it, regrets.
Check back every now and then, but obsessing over these cures..it becomes a never ending cycle.
Now on a side note, Ive briefly skimmed the latest stuff that you guys are getting excited about, just thought Id rant about it for a sec.
Elastagen, and Micro coring.
For Elastagen, just because Allargen is willing to pay an absurd amount for it,does not automatically imply a directcorrelationto itsefficacy. They are a leader in the space of fillers, if theres a another filler that they believe could even become 2nd rank to them, theyll buy them out, no reason to take chances to wait and see if it actually works or not. Second, this is nowhere near scarless healing, its still a filler,hopefully it integrates with your skin generates elastin toimproveappearance and giveextra elasticity.. all good things, can potentially do a lot for rolling scars or stretch marks, but thats about it,truly atrophic stuff, you would need a lot more, would definitely probably need subcision in conjunction and maybe other stuff if you want to truly see something.
Micro coring.. its an interesting one.. if it truly does what I think it says, removing cores at a diameter at which the holes will just close themselves. I think its true for healthy tissue to contract itself to fill thegap that was extracted.I dont know that scar tissue behaves the same way.. but if it does, then yes in theory you can just repeatedly extract skin, until most of the scar tissue has been excised, if it supposedly removes 5% of surface area at a time.. youre looking at a lot of treatments. Now if its through out yourface.. how much of your skin is a safe amount to be extracting. Following this therell be a lot of stretched skin. I dont see this being viable for large areas, since the real issue is not being tackled, this is just a fancy excision, which could be great for a couple scars here and there though.
A contradictorythingIve read somewhereis that the core extracted is actually regenerated by the body with healthy tissue.. which would be really interesting. Ill try to read more about this.
PS.. what the hell happened to the holy grail hydrogel that everyone was talking aboutfor the past few years. Dr Sun just thought he had something but actually didnt?
There was also something calledFS2..
Anyways, stay safe guys!
I agree with this comment. The question is whether micro-coring can only remove the scar area. I think I have to wait a little longer
https://instagram.com/skin_chaeum?igshid=8bob2w5jy2w3 Did anyone hear aboutthis subcision technique , do u think its real ?
So long as the scar being treated isn't hyertrophic or lacking a ton of volume I really don't see a problem in micro-coring extracting scar tissue and it closing up normally. The device is an array of hollow needles that creates cores of complete skin right down to and a bit after the dermis even hitting the fat(it suctions these cores out of the skin), the body's response to small injuries from needles even to scars is to close the hole up, if microneedling doesn't leave open holes in scars then its a no-brainer this won't either. The info on how it works is in the patent, the greater the area removed the less skin you have there as the areas treated close up like an open zipper. My hope is pretty high but its not like I'm deathly focused on it working. The coming months/years will be the answer.
On 1/27/2021 at 2:27 PM, ParisN said:
Yes from Cytrellis! I agree it's probably the FDA approvals which have been probably further delayed by COVID ... I wonder how much itwill influence scar treatment!
I looked up that company and nowhere does it say anything about helping acne scars.
On 2/21/2021 at 9:31 AM, DinkumFridge said:I agree with this comment. The question is whether micro-coring can only remove the scar area. I think I have to wait a little longer
I think you will have to wait years.....this thread has already been going on for now 14 years.
On 2/21/2021 at 9:31 AM, DinkumFridge said:I agree with this comment. The question is whether micro-coring can only remove the scar area. I think I have to wait a little longer
yea like years
2 hours ago, nikkigirl said:I looked up that company and nowhere does it say anything about helping acne scars.
It clearly states it online (listed in first page of google search, under INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY) and a clinical trial (ClinicalTrials.gov Identifier: NCT03782038) was conducted specifically for scars.
Also, in medicine treatments are constantly repurposed to treat different conditions i.e. botox was originally intended for chronic migraines and then its application became relevant to the cosmetic industry. However, at least here the device is targeted to treat scars too from the outset which is not a bad start!!! Whether it has shown positive or promising results is another matter 
There will be a conference around April on the effectiveness of microcoring as a rejuvenation device. Also, though not cytrellis but fig 131 on recrossmedia device is about using microcoring to remove scars, they have over 7 examples on both using microcoring for w plasty, z plasty and using it only to remove a hypotrophic scar and raise the scar edge to the level of normal skin with continuing treatments to remove the scar. Cytrellis patent mentions it being used to remove scars from acne, accident, etc so the two aren't far off, it's even in the patent that being such an outpatient procedure it could be done in a spa, so if it's released and becomes mainstream it doesn't stop you from going to get it done on your scar even if it's mostly used for skin tightening elsewhere. Best of luck to everyone, hope it all works out well, won't be devastated if it doesn't.
![Screenshot_2021-02-23 US10702684B2 - Systems, devices and methods for fractional resection, fractional skin grafting, fract[...].png](https://static.acne.org/ipb_uploads/monthly_2021_02/1211667430_Screenshot_2021-02-23US10702684B2-Systemsdevicesandmethodsforfractionalresectionfractionalskingraftingfract....png.85e39a76abbf47f77cff847eecc98727.png)
![Screenshot_2021-02-23 US10661063B2 - Systems, devices and methods for fractional resection, fractional skin grafting, fract[...].png](https://static.acne.org/ipb_uploads/monthly_2021_02/284784152_Screenshot_2021-02-23US10661063B2-Systemsdevicesandmethodsforfractionalresectionfractionalskingraftingfract....png.9553e9ce5d51d28d95a0dc0cc965e84c.png)
On 2/19/2021 at 8:37 PM, Didikaxonim1 said:where did you get this information from?
Rob Daniels, the ex-CEO of Elastagen. He's very nice and really tries to answer people's questions as soon as he can, and as well as he can.
On 2/19/2021 at 12:28 AM, Gurney Shellon said:
On 2/23/2021 at 4:43 PM, David4bay said:There will be a conference around April on the effectiveness of microcoring as a rejuvenation device. Also, though not cytrellis but fig 131 on recrossmedia device is about using microcoring to remove scars, they have over 7 examples on both using microcoring for w plasty, z plasty and using it only to remove a hypotrophic scar and raise the scar edge to the level of normal skin with continuing treatments to remove the scar. Cytrellis patent mentions it being used to remove scars from acne, accident, etc so the two aren't far off, it's even in the patent that being such an outpatient procedure it could be done in a spa, so if it's released and becomes mainstream it doesn't stop you from going to get it done on your scar even if it's mostly used for skin tightening elsewhere. Best of luck to everyone, hope it all works out well, won't be devastated if it doesn't.
Lol......start from the beginning of this thread and keep reading.....treatment after treatment failed.....but people will gladly take your money.....it wasn't too long ago this thread was posting how great Polarity was.
I think given the various studies and discoveries made,Im pretty optimistic that skin regeneration is something thatll come one day.
But it could take a while, most parties working on it are only concerned with specific cases, and are not tackling the issue holistically. The ones that are really looking into itseem to be doing it only for academic reasons, publishing the hundredth research paper as to how salamanders hold the key! They dont have the pressures of timely deliverables to really be going all in on it and have nothing invested on the matter. Takeelastagen as an example for that, look up how far back that project has been going on.
Unless someone like Elon Musk decides thattacklingskin regeneration would disrupt the whole market, the progress will continue to be at aturtles pace and will probably only be solved as a result of an accident like most major discoveries do.
For every one else here, stay updated on all the progress being made, I do and its fascinating stuff. But understand that unless youre someone whos in the field,doing a deep dive research into thesetopics will not speed up the process of delivering scar free healing. Itll come the day it comes regardless of what we do here,and the experts on the matter will be aware of it and deliver the news to us,someone like Dr.Davin Lim maybe,definitely not your local dermatologist.
On 2/22/2021 at 1:56 AM, Skin Pessimist said:I'm a bit higher on the concept of elastagen than others here, especially for rolling scars. However, I'm skeptical that Allergan will focus on acne scars applications. Probably just wrinkles & stretch marks.
There's (probably) still years before it hits the market too
I was originally extremely pessimistic, but I'm coming around to it a little bit. If Imake a bubble with my cheeks, almost all the scarring disappears. It would stand to reason that a tropoelastin injection would accomplish a similar thing but permanently. That has mesomewhat optimistic.
