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[Sticky] Scarless Healing

 
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(@ptaa)

Posted : 11/19/2020 1:32 am

On 11/17/2020 at 6:01 AM, lehran said:

I don't think so. I know that, at some point, elastagen's products were in allergan's pipeline, but since they've been absorbed by abbvie, they stopped appearing there.

Is theirproduct pipeline limited to injections for the near future? I really don't see injections fixing the scars of mostpeople here. Many of us have substantial texture issues even at the epidermal level. An injection likely wont hide that since even if the dermal strutures are regenerated, there's still a messed up epidermis.

I saw that they're working on excision regeneration technology, but that's looking way toward the future. I don't want to come off as a confrontational or dismissive, but what has you thinking this will give an 80-90% improvement? I saw that you stated that percentage earlier in the thread and I'm skeptical of it. I'm still interested in Elastagen, but from a technical standpoint I currently see more promise in a method that excises skin, like microcoring.

Having said that, if they eventually release tropoelastin sheets that can regenerate somewhat large amounts of excised skin perfectly, I'll be 100% on board. That's the future and is very exciting. I dont think it's close though.

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(@lehran)

Posted : 11/19/2020 2:11 pm

12 hours ago, PTAA said:

Is theirproduct pipeline limited to injections for the near future? I really don't see injections fixing the scars of mostpeople here. Many of us have substantial texture issues even at the epidermal level. An injection likely wont hide that since even if the dermal strutures are regenerated, there's still a messed up epidermis.

I saw that they're working on excision regeneration technology, but that's looking way toward the future. I don't want to come off as a confrontational or dismissive, but what has you thinking this will give an 80-90% improvement? I saw that you stated that percentage earlier in the thread and I'm skeptical of it. I'm still interested in Elastagen, but from a technical standpoint I currently see more promise in a method that excises skin, like microcoring.

Having said that, if they eventually release tropoelastin sheets that can regenerate somewhat large amounts of excised skin perfectly, I'll be 100% on board. That's the future and is very exciting. I dont think it's close though.

I actually completely agree with you when you mention different types of scars. I, for example, can't see how a simple injection would address hypertrophic scars, which are very raised, and sometimes super severe.

The main focus of elastagen right now is atrophic scars, as the idea is to repair the dermis and replace the voids left by the damage with a tropoelastin-based IMPLANT (the word implant is important here). It's basically the same idea for stretch marks and acne scars: using a synthetic 3D skin (which is what they created, basically) to cover the damage.

They're really not there yet when it comes to more severe kinds of scaring like hypertrophic scars. If you read some of my older comments (thank you for that btw), you'll find one with tons of links about elastagen. I believe there's one (probably an audio file) where Tony Weiss mentions that they still have a long way to go for more severe scars, and I really doubt that JUST a filler is the solution. It's probably going to be a combination of things.

So no, you're not coming off as confrontational or anything, you actually made very good points.

Ah, also, about the 80-90% improvement, I wrote something about that (concerning the kind of improvement one should expect), as people usually have the wrong idea about what that means, did you find that part?

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(@miro)

Posted : 11/20/2020 9:44 am

On 11/19/2020 at 7:32 AM, PTAA said:

Is theirproduct pipeline limited to injections for the near future? I really don't see injections fixing the scars of mostpeople here. Many of us have substantial texture issues even at the epidermal level. An injection likely wont hide that since even if the dermal strutures are regenerated, there's still a messed up epidermis.

I saw that they're working on excision regeneration technology, but that's looking way toward the future. I don't want to come off as a confrontational or dismissive, but what has you thinking this will give an 80-90% improvement? I saw that you stated that percentage earlier in the thread and I'm skeptical of it. I'm still interested in Elastagen, but from a technical standpoint I currently see more promise in a method that excises skin, like microcoring.

Having said that, if they eventually release tropoelastin sheets that can regenerate somewhat large amounts of excised skin perfectly, I'll be 100% on board. That's the future and is very exciting. I dont think it's close though.

Well , i asked my friend dr ( not dermatologist ) in my home country before i started this acne scars treatment what he thinks about it.

He said to me: Improvement is possible, some scars will look a lot better some less , but dont expect drastic improvement ( 80-90 % ) or complet removal of scar, technology is not there yet, he told me to remove scar you have to excise it - "cut it out " scar tissue, but then of course it creates another scar which can look even worse then original scarsand also not every scars - dent- depression in skin is suitable for excision.

Simply put you d have to remove scars tissue and replace it with new skin . Thats why todays treatment are not "good enough", you can inject filler and it can lift the floor of the scars and then with laser or peeling ablate the surface and it will look better but scartissue is still there thats why its called correction, f.e. sometimes u have scarsthat islifted with subc + filler but u still see scar, it has different color and looks different then surounding skin because its the scar tissue .

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(@anushkaaa)

Posted : 11/20/2020 11:28 am

1 hour ago, Miro said:

Well , i asked my friend dr ( not dermatologist ) in my home country before i started this acne scars treatment what he thinks about it.

He said to me: Improvement is possible, some scars will look a lot better some less , but dont expect drastic improvement ( 80-90 % ) or complet removal of scar, technology is not there yet, he told me to remove scar you have to excise it - "cut it out " scar tissue, but then of course it creates another scar which can look even worse then original scarsand also not every scars - dent- depression in skin is suitable for excision.

Simply put you d have to remove scars tissue and replace it with new skin . Thats why todays treatment are not "good enough", you can inject filler and it can lift the floor of the scars and then with laser or peeling ablate the surface and it will look better but scartissue is still there thats why its called correction, f.e. sometimes u have scarsthat islifted with subc + filler but u still see scar, it has different color and looks different then surounding skin because its the scar tissue .

I underwent 1 laser stretchmarks reduction and let me be honest, I saw a huge improvement. The doctor said that the current technology can improve the appearance of scars by filling of the scars which is actually not regeneration. As for me my stretchmarks are wayyy too many but they are thin so the dents can be filled better. But the thing with elastagen is that when they inject a Synthetic skin into your dermal layer it goes into regeneration of the skin something humans are not capable of ( example reptiles like snakes can regenerate their skin , not us) . The elastin and related components form before birth and when we get scars ex acne scars stretchmarks, current technology can reduce their appearance and depth upto a good amount if treatments are taken timely with multiple sessions but the skin won't be the way it was before. This is what is amusing about tropoelastin injections that bring the regeneration thing into play. I just wan say, we can't suggest the percentage improvement from now until we get proper evidence or human examples. If it is really able to regenerate skin, then we can literally imagine ourselves with near perfect skin but if not , the current technology is what we need to deal with. I will continue my laser session but if elastagen comes in a couple years, would try that too.

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(@miro)

Posted : 11/20/2020 3:40 pm

4 hours ago, Anushkaaa said:

I underwent 1 laser stretchmarks reduction and let me be honest, I saw a huge improvement. The doctor said that the current technology can improve the appearance of scars by filling of the scars which is actually not regeneration. As for me my stretchmarks are wayyy too many but they are thin so the dents can be filled better. But the thing with elastagen is that when they inject a Synthetic skin into your dermal layer it goes into regeneration of the skin something humans are not capable of ( example reptiles like snakes can regenerate their skin , not us) . The elastin and related components form before birth and when we get scars ex acne scars stretchmarks, current technology can reduce their appearance and depth upto a good amount if treatments are taken timely with multiple sessions but the skin won't be the way it was before. This is what is amusing about tropoelastin injections that bring the regeneration thing into play. I just wan say, we can't suggest the percentage improvement from now until we get proper evidence or human examples. If it is really able to regenerate skin, then we can literally imagine ourselves with near perfect skin but if not , the current technology is what we need to deal with. I will continue my laser session but if elastagen comes in a couple years, would try that too.

First treatment for my acne scars was Fractional CO2, it did absolutly nothing for my scaring. Its true that dr used very conservative setting. Then I made my research and tried some manual methods first, at the end i will maybe try again Fractional CO2 with some serious setting, I hope i see some improvement , cause first time it was just wasted time and money.

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(@anushkaaa)

Posted : 11/21/2020 12:27 am

8 hours ago, Miro said:

First treatment for my acne scars was Fractional CO2, it did absolutly nothing for my scaring. Its true that dr used very conservative setting. Then I made my research and tried some manual methods first, at the end i will maybe try again Fractional CO2 with some serious setting, I hope i see some improvement , cause first time it was just wasted time and money.

Once I went to a very reputable doctor for my legs stretchmarks.he said all kinds of big things and stuff and after 2 treatment I found nothing but hyperpigmentation on my legs. I microneedled with hyaluronic acid and they have almost disappeared only I see them as I know they exist. My sudden weight gain left me with deep arm stretchmarks everywhere on my arms so this time I decided to go to a rather local doctor. I said her to operate the laser with utmost power on one and not so high on the other. I don't know if u can see this but the pic is after 10 days ( before on left and after on right) now it's been 3 weeks and I really feel they have blended with my skin. But obviously the dents are visible if I stretch my skin slightly but the depth has definitely reduced. It's not the lightning difference trust me , they have improved . I have a minimum of 8 treatment combination with prp and radio-frequency tightening and maximum of 12. The other hand with less laser power had less of a result. I hope u can see the difference. The lightning is a problem here but trust me this worked

20201117_203932-COLLAGE.jpg

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(@scarface100)

Posted : 11/21/2020 5:02 am

Hey, has anyone heard from Sunogel? I've read up on apaper of theirs from 2017and their discoveries + preclinical trialsseemed quite promising for scarless healing. There hasn't been much, if any, activity from the company for the past year on social media. Anyone know if their treatment is still under development? I've emailed them a few days ago, but no response - maybe it might be too early to judge though.

Thanks!

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(@didikaxonim1)

Posted : 11/21/2020 6:13 am

1 hour ago, ScarFace100 said:

Hey, has anyone heard from Sunogel? I've read up on apaper of theirs from 2017and their discoveries + preclinical trialsseemed quite promising for scarless healing. There hasn't been much, if any, activity from the company for the past year on social media. Anyone know if their treatment is still under development? I've emailed them a few days ago, but no response - maybe it might be too early to judge though.

Thanks!

I wrote to them in October and they answered me. Dr. Sun told me, WE are working on it now."

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(@scarface100)

Posted : 11/21/2020 1:21 pm

7 hours ago, Didikaxonim1 said:

I wrote to them in October and they answered me. Dr. Sun told me, WE are working on it now."

Yep, he just replied to my email too. Not entirely sure when clinical trials will start though. Interesting to see that they're still going. Let's hope things work out.

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(@nikkigirl)

Posted : 11/22/2020 2:47 pm

On 10/15/2020 at 11:33 AM, nikkigirl said:

Hope is eternal at this forum....i have seen all the treatments and yes i have had filler ect and nothing has done a lot to my scars and made me poorer. You hope and hope but nothing ever comes to fruitation.Live your life and don't look in the mirror!

doubt it.

On 10/28/2020 at 1:51 PM, onefatalgoose said:

I have.....been trying to....scam you.  Am I understanding this correctly?  What product am i selling?    Don't use sulfur to help with scar healing if your are not comfortable with the idea.  In small quantities it can be very effective but if the idea is too scary to anyone....it's pretty simple:  Don't use it and keep doing what you're doing.  I offered a suggestion from personal experience as well as outside experience..  It works.  Takes time.  And is not an overnight solution.  And it is also not the only thing you should be ingesting. 

Report me all you want.  I have not suggested a single name brand or asked anyone to purchase anything from me.  And why would that be.....lets all use our brains here.....hmm.....why would that be.....because.... I am sharing  an idea.  Knowledge.  And it's free 99.  Ya don't gotta try it.  But i WILL argue till I am blue in the face about how effective it is.  In small quantities over a long period of time.  Plenty of foods out there you can incorporate that are naturally high in sulfur. 

This is fun. I have missed these discussions.  I also know what I'm talking about.  Been around acne long enough .  And been around people who have shared so much wisdom over the years.  Sulfur is ONE component of acne healing.  Scar healing.  It is not the "one and only"  

eating sulfur...lol!  I have some Peter Popoff's miracle spring water to sell you and it is safer than sulfur and it will do the same thing.....nothing!

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(@scarcure)
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(@adadad)

Posted : 11/28/2020 9:24 am

Elastagen scientific papers published.

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MemberMember
117
(@gantz)

Posted : 11/28/2020 11:27 am

2 hours ago, adadad said:

Elastagen scientific papers published.

thx

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MemberMember
657
(@miro)

Posted : 11/28/2020 11:39 am

2 hours ago, adadad said:

Elastagen scientific papers published.

Do u have link ?

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MemberMember
24
(@nikkigirl)

Posted : 11/28/2020 11:43 am

On 11/19/2020 at 1:32 AM, PTAA said:

Is theirproduct pipeline limited to injections for the near future? I really don't see injections fixing the scars of mostpeople here. Many of us have substantial texture issues even at the epidermal level. An injection likely wont hide that since even if the dermal strutures are regenerated, there's still a messed up epidermis.

I saw that they're working on excision regeneration technology, but that's looking way toward the future. I don't want to come off as a confrontational or dismissive, but what has you thinking this will give an 80-90% improvement? I saw that you stated that percentage earlier in the thread and I'm skeptical of it. I'm still interested in Elastagen, but from a technical standpoint I currently see more promise in a method that excises skin, like microcoring.

Having said that, if they eventually release tropoelastin sheets that can regenerate somewhat large amounts of excised skin perfectly, I'll be 100% on board. That's the future and is very exciting. I dont think it's close though.

Sure it is....they will gladly take your money!

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(@gantz)

Posted : 11/28/2020 12:07 pm

article requires a subscription for $ 20, meh

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MemberMember
117
(@gantz)

Posted : 11/28/2020 1:57 pm

2 hours ago, Miro said:

Do u have link ?

https://jddonline.com/articles/dermatology/S1545961620P1166X

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MemberMember
657
(@miro)

Posted : 11/28/2020 2:09 pm

11 minutes ago, gantz said:

Hm u need to register , did anyonehere read whole arcticle and if so whats the conclusion ?

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MemberMember
97
(@lehran)

Posted : 11/29/2020 6:08 am

It's fine you guys, I'll buy it, and share it afterwards. Don't bother buying it, I'll take care of it.

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MemberMember
97
(@lehran)

Posted : 11/29/2020 8:20 am

There you go, have fun guys. IMPORTANT: the last 3 imgur link are just one page, but it was too long to make a single screenshot, so open all 3 at the same time to avoid getting confused

 

https://imgur.com/a/SzioKlm

https://imgur.com/a/wBu82Dc

https://imgur.com/a/VA8b3gG

https://imgur.com/a/kp1ISjH

https://imgur.com/a/SFKVguU

https://imgur.com/a/zTAxQU9

https://imgur.com/a/JyIuuiH

https://imgur.com/a/ibrLMLh

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MemberMember
657
(@miro)

Posted : 11/29/2020 8:37 am

16 minutes ago, lehran said:

There you go, have fun guys. IMPORTANT: the last 3 imgur link are just one page, but it was too long to make a single screenshot, so open all 3 at the same time to avoid getting confused

 

https://imgur.com/a/SzioKlm

https://imgur.com/a/wBu82Dc

https://imgur.com/a/VA8b3gG

https://imgur.com/a/kp1ISjH

https://imgur.com/a/SFKVguU

https://imgur.com/a/zTAxQU9

https://imgur.com/a/JyIuuiH

https://imgur.com/a/ibrLMLh

What do you personally think About it ?

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MemberMember
117
(@gantz)

Posted : 11/29/2020 10:39 am

2 hours ago, lehran said:

There you go, have fun guys. IMPORTANT: the last 3 imgur link are just one page, but it was too long to make a single screenshot, so open all 3 at the same time to avoid getting confused

 

https://imgur.com/a/SzioKlm

https://imgur.com/a/wBu82Dc

https://imgur.com/a/VA8b3gG

https://imgur.com/a/kp1ISjH

https://imgur.com/a/SFKVguU

https://imgur.com/a/zTAxQU9

https://imgur.com/a/JyIuuiH

https://imgur.com/a/ibrLMLh

Thx a lot lot lot!!!

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(@Anonymous)

Posted : 11/29/2020 11:19 am

Interesting research. Would be good to see it on scarred skin and not just on biopsy slides. All in good time though.

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MemberMember
4
(@anushkaaa)

Posted : 12/02/2020 12:15 pm

Hey guys did anyone read the papers?? Do u guys have any idea when can elastagen come. A woman on Quora said that we can expect it super soon. And once we get these fillers in our skin, for stretchmarks and scars, do we have to get them again and again??? Any further news? . Do u know when they will release pictures of human trials??. Please respond

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MemberMember
97
(@lehran)

Posted : 12/02/2020 6:05 pm

6 hours ago, Anushkaaa said:

Hey guys did anyone read the papers?? Do u guys have any idea when can elastagen come. A woman on Quora said that we can expect it super soon. And once we get these fillers in our skin, for stretchmarks and scars, do we have to get them again and again??? Any further news? . Do u know when they will release pictures of human trials??. Please respond

Hey there ! I actually shared the papers a few days before. Check them out on page 470. I would be really interested to see the source on quora where you mentioned that woman who said that the product would be out very soon though, thank you.

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