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[Sticky] Scarless Healing

 
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117
(@gantz)

Posted : 07/23/2020 10:30 am

4 hours ago, Armanilko said:

https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf

Go to page 18, all your questions are answered there. And here's probably the most interesting quote:

"With sheets of Tropoelastin laid on the damaged site, a synthetic skin forms. According to Professor Weiss it halves skin repair time, with resulting eco-nomic benefits for both patient and health system. It allows a patients own blood vessels and cells to grow through it, becoming a soft flexible replace-ment skin that can sweat, and have hair follicles re-grow. It significantly minimises or removes scarring"

Sounds like some sci-fi... I knew only about 3 injectable gels from interview with Elastagen's ceo

Still injectable sounds very confusing to me, because the scar tissue needs to be removed anyway. It turns out that the application of the injactable should be together with some accompanying actions ...

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(@armanilko)

Posted : 07/23/2020 10:41 am

7 minutes ago, gantz said:

Sounds like some sci-fi... I knew only about 3 injectable gels from interview with Elastagen's ceo

Still injectable sounds very confusing to me, because the scar tissue needs to be removed anyway. It turns out that the application of the injactable should be together with some accompanying actions ...

Which is why the focus for elastahe, right now is on atrophic scars (and stretch marks are part of that category) and not hypertrophic scars: filling a a zone devoid of skin with synthethic skin in order to repair its surface. This is something people have been mentioning several times before here.

There's a reason why the product is in allergan's pipeline right now, and that we're getting scientific papers on stretch marks and acne scars at the end of the year, but not hypertrophic scars.

If you're part of the latter category, Anthony Weiss and Rob daniels said it would take a few more years for them to find an application to that, but that they're getting there, so be patient.

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36
(@david4bay)

Posted : 07/23/2020 10:57 am

Thanks so much Armanilko for the info...the scald scar on my chin is flat and discoloured with pores(yes pores) growing a bit of hair next to beard, with this info I was thinking of maybe a laser dermabrasion + elastagen graft/filler may make the area heal properly(as I can still see sebacious filaments under the scar).

The nature of my scar is the prime reason I'm leaning on to microcoring as against elastagen as I want the skin that epitheliases to retain the hairs, pores and sebacious filaments whilst solving the out of place scar appearance scar tissue has.

 

Funny enough I have ice pick and 2 box scars but outside of my teenage years they've never bothered me, only the scald accident that burned off a dime size of skin on my chin below my left lower lip bothers me.

 

Either way the future does look great and I'd be keeping an eye on these two procedures, I'd imagine tripoelastin serums may even start being used with microneedling on scars like mine to slowly erase scarring substantially if not completely with microcoring.

 

Expectations in check though, thanks.

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5
(@didikaxonim)

Posted : 07/24/2020 1:29 am

14 hours ago, Armanilko said:

Which is why the focus for elastahe, right now is on atrophic scars (and stretch marks are part of that category) and not hypertrophic scars: filling a a zone devoid of skin with synthethic skin in order to repair its surface. This is something people have been mentioning several times before here.

There's a reason why the product is in allergan's pipeline right now, and that we're getting scientific papers on stretch marks and acne scars at the end of the year, but not hypertrophic scars.

If you're part of the latter category, Anthony Weiss and Rob daniels said it would take a few more years for them to find an application to that, but that they're getting there, so be patient.

Does elastagen produce new skin?

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657
(@miro)

Posted : 07/24/2020 1:57 am

19 hours ago, Armanilko said:

https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf

Go to page 18, all your questions are answered there. And here's probably the most interesting quote:

"With sheets of Tropoelastin laid on the damaged site, a synthetic skin forms. According to Professor Weiss it halves skin repair time, with resulting eco-nomic benefits for both patient and health system. It allows a patients own blood vessels and cells to grow through it, becoming a soft flexible replace-ment skin that can sweat, and have hair follicles re-grow. It significantly minimises or removes scarring"

Sounds like sci - fi , so when we can have all our scarring removed by this new technology ? 🙂

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21
(@armanilko)

Posted : 07/24/2020 6:21 am

4 hours ago, Miro said:

Sounds like sci - fi , so when we can have all our scarring removed by this new technology ? 🙂

For stretch marks and acne scars (not icepick acne scars mind you), it's anywhere between 1-4 years apparently. I don't know more than that.

My bet is something like 2 years since we're getting the publication of the clinical studies at the end of the year and their product is in allergan's pipeline, but my guess is as good as yours honestly, it's just speculation.

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78
(@scarcure)

Posted : 07/24/2020 8:04 am

1 hour ago, Armanilko said:

For stretch marks and acne scars (not icepick acne scars mind you), it's anywhere between 1-4 years apparently. I don't know more than that.

My bet is something like 2 years since we're getting the publication of the clinical studies at the end of the year and their product is in allergan's pipeline, but my guess is as good as yours honestly, it's just speculation.

Why not ice pick scars ? how does that make any sense ?

 

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21
(@armanilko)

Posted : 07/24/2020 8:06 am

Just now, Scarcure said:

Why not ice pick scars ? how does that make any sense ?

 

wasn"t lehran the one who mentioned that he asked, and that it wouldn't work right away? I think there was a discussion about this, and he said it would take more research. Don't take my word for it, just search a few months before

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(@albaneso)

Posted : 07/24/2020 8:40 am

What about hypertrophic scars??

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5
(@didikaxonim)

Posted : 07/25/2020 3:12 am

Write

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36
(@david4bay)

Posted : 07/25/2020 10:04 am

On 7/24/2020 at 7:29 AM, Didikaxonim said:

Does elastagen produce new skin?

"According to Professor
Weiss it halves skin repair time, with resulting economic benefits for both patient and health system.
It allows a patients own blood vessels and cells to
grow through it, becoming a soft flexible replacement skin that can sweat, and have hair follicles regrow. It significantly minimises or removes scarring."

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MemberMember
78
(@scarcure)

Posted : 07/26/2020 6:18 am

20 hours ago, David4bay said:

"According to Professor
Weiss it halves skin repair time, with resulting economic benefits for both patient and health system.
It allows a patients own blood vessels and cells to
grow through it, becoming a soft flexible replacement skin that can sweat, and have hair follicles regrow. It significantly minimises or removes scarring."

It either significantly reduces or removes scarring .... if a scar is removed it would mean it's regenerated with all appendages like hair follicles , sweat glands , oil glands etc ...

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36
(@david4bay)

Posted : 07/26/2020 11:32 am

5 hours ago, Scarcure said:

It either significantly reduces or removes scarring .... if a scar is removed it would mean it's regenerated with all appendages like hair follicles , sweat glands , oil glands etc ...

Honestly I'm on the fence about elastagen. What I fear from the wording there is the "significantly reduces" line, as I picture maybe my scar being excised out and replaced by elastagen, only to have a rim of scar tissue from the method of excision surrounded by healthy tissue that has grown through the polymers. I'd love to see the before and after photos of this technology when it's out(especially on colored skin) because I am sceptical that even if this thing works you're at the mercy of the surgeon/dermatologist that's going to do this and the method they use to excise the scar tissue. I hope microcoring will be a more efficient method as even if appendages does not grow back you would have less scar tissue and can selectively target more over time, fingers crossed everyone gets treated well as these new technologies and more come out.

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41
(@skin-pessimist)

Posted : 07/28/2020 11:43 am

On 7/26/2020 at 10:32 AM, David4bay said:

Honestly I'm on the fence about elastagen. What I fear from the wording there is the "significantly reduces" line, as I picture maybe my scar being excised out and replaced by elastagen, only to have a rim of scar tissue from the method of excision surrounded by healthy tissue that has grown through the polymers. I'd love to see the before and after photos of this technology when it's out(especially on colored skin) because I am sceptical that even if this thing works you're at the mercy of the surgeon/dermatologist that's going to do this and the method they use to excise the scar tissue. I hope microcoring will be a more efficient method as even if appendages does not grow back you would have less scar tissue and can selectively target more over time, fingers crossed everyone gets treated well as these new technologies and more come out.

Hopefully we get the study results by the end of the year

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78
(@scarcure)

Posted : 07/29/2020 5:05 am

I want to know also , Can laser effect the 3rd layer of your skin ? i had the Pixel Laser 2940 at the Private Clinic of Harley Street ... i was scarred all over my face with orange peel skin ( micro scarring essentially ) and creases around my eyes and cheeks .... i wanted to know are these the signs of just the dermis being badly effected or deeper 3rd layer ( i doubt the 3rd layer of skin is affected as i still can make a smile and frown etc )... but the scarring makes my face feel really dry .... and i know only complete skin regeneration is the only thing that's going to cure all this mess on my face ... as i know 3rd degree burns go all the way to the 3rd layer ( the hypodermis ) ... the saving grace is i can grow somewhat a full beard ... which indicates my face isn't completely full of scars ( healthy and unscarred skin produces hair follices , sweat glands and oil glands ... i don't believe the bullshit that scarred skin can have hair growth , because that goes against mammal physiology )

Am 31 years old now and had scarring since i was 18 years old ... hopefully compete skin regeneration comes true this decade as i can't take this bullshit no more ....

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21
(@armanilko)

Posted : 07/30/2020 10:54 am

On 7/28/2020 at 6:43 PM, Skin Pessimist said:

Hopefully we get the study results by the end of the year

Either Q4 this year or Q1 2021 if we're really unlucky

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5
(@didikaxonim)

Posted : 07/31/2020 8:57 am

22 hours ago, Armanilko said:

Either Q4 this year or Q1 2021 if we're really unlucky

Why unlucky?

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6
(@scarlessfuture)

Posted : 07/31/2020 12:06 pm

On 7/29/2020 at 6:05 AM, Scarcure said:

I want to know also , Can laser effect the 3rd layer of your skin ? i had the Pixel Laser 2940 at the Private Clinic of Harley Street ... i was scarred all over my face with orange peel skin ( micro scarring essentially ) and creases around my eyes and cheeks .... i wanted to know are these the signs of just the dermis being badly effected or deeper 3rd layer ( i doubt the 3rd layer of skin is affected as i still can make a smile and frown etc )... but the scarring makes my face feel really dry .... and i know only complete skin regeneration is the only thing that's going to cure all this mess on my face ... as i know 3rd degree burns go all the way to the 3rd layer ( the hypodermis ) ... the saving grace is i can grow somewhat a full beard ... which indicates my face isn't completely full of scars ( healthy and unscarred skin produces hair follices , sweat glands and oil glands ... i don't believe the bullshit that scarred skin can have hair growth , because that goes against mammal physiology )

Am 31 years old now and had scarring since i was 18 years old ... hopefully compete skin regeneration comes true this decade as i can't take this bullshit no more ....

Actually, I have several thick scars where hair comes out of them. It really depends on genes and the severity of the wound. Hair follicles are normally present deep in the dermis and they don't necessarily get damaged after an injury. Hair continues to grow, eventually pocking through the newly formedscar tissue.

What you have is hyperpigmentation which takes forever for some people to resolve. It is not scar tissue. I recently got a second degree burn (blisters all over), it healed within 2 weeks but normal skin colour has not returned. It likely never will but who cares.

For some of my skin injuries, it has taken them well over 10 years for the hyper/hypopigmentation to resolve.

Lasers do nothing for indentented scars and they essentially burn the top layers of the skin (epidermis) which as thick as a sheet of paper. Whenever, the dermis is damaged following injury, scar formation is guaranteed. If not done right, lasers burn through the dermis and you end up in a worse situation than before, this is a second degree burn, where the skin blisters. A third degree burn extends deep into the dermis or hyperdermis (fat). Large chunks of skin are vaporized, exposing muscle and bone. I think you are far from that.

Unfortunately, nobody has perfect skin and what you see on celebrities is not reality. Many actors/actresses out there have craters all over their face due to acne, chicken pox, etc. Get a grip.

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MemberMember
117
(@gantz)

Posted : 07/31/2020 5:58 pm

I am curious about micro coring. If it really leaves no scar in healthy skin, does it work the same way on scar tissue? I mean, are the pores formed by skin withdrawal able to heal by tightening?

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MemberMember
78
(@scarcure)

Posted : 07/31/2020 6:08 pm

6 hours ago, Scarlessfuture said:

Actually, I have several thick scars where hair comes out of them. It really depends on genes and the severity of the wound. Hair follicles are normally present deep in the dermis and they don't necessarily get damaged after an injury. Hair continues to grow, eventually pocking through the newly formedscar tissue.

What you have is hyperpigmentation which takes forever for some people to resolve. It is not scar tissue. I recently got a second degree burn (blisters all over), it healed within 2 weeks but normal skin colour has not returned. It likely never will but who cares.

For some of my skin injuries, it has taken them well over 10 years for the hyper/hypopigmentation to resolve.

Lasers do nothing for indentented scars and they essentially burn the top layers of the skin (epidermis) which as thick as a sheet of paper. Whenever, the dermis is damaged following injury, scar formation is guaranteed. If not done right, lasers burn through the dermis and you end up in a worse situation than before, this is a second degree burn, where the skin blisters. A third degree burn extends deep into the dermis or hyperdermis (fat). Large chunks of skin are vaporized, exposing muscle and bone. I think you are far from that.

Unfortunately, nobody has perfect skin and what you see on celebrities is not reality. Many actors/actresses out there have craters all over their face due to acne, chicken pox, etc. Get a grip.

Am sorry but if you're giving this flippant remark of " get a grip " where you never seen how i look , and also you're on a forum which is filled with people desperate ( like me ) to have their skin regenerated to their original form ... it then begs the question ... what the fuck are you doing here ? .... also wrong hairdo NOT grow on scarred tissue ... that's retarded , that goes against how we as mammals evolved , once we have a scar it loses the function and the appendages the originally healthy skin had ... that being oil , sweat glands , and yes HAIR follicles.

But i do appreciate your reassurance that the scarring caused by the useless c**t that perform the laser on me isn't deep enough to reach my hypodermis .... so that i do appreciate so thank you.

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MemberMember
117
(@gantz)

Posted : 07/31/2020 7:57 pm

On 7/19/2020 at 7:19 PM, Armanilko said:

Mail conversations with them, pure and simple.

can you write theiremail?

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MemberMember
6
(@scarlessfuture)

Posted : 07/31/2020 10:47 pm

4 hours ago, Scarcure said:

Am sorry but if you're giving this flippant remark of " get a grip " where you never seen how i look , and also you're on a forum which is filled with people desperate ( like me ) to have their skin regenerated to their original form ... it then begs the question ... what the fuck are you doing here ? .... also wrong hairdo NOT grow on scarred tissue ... that's retarded , that goes against how we as mammals evolved , once we have a scar it loses the function and the appendages the originally healthy skin had ... that being oil , sweat glands , and yes HAIR follicles.

But i do appreciate your reassurance that the scarring caused by the useless c**t that perform the laser on me isn't deep enough to reach my hypodermis .... so that i do appreciate so thank you.

I think you should be reported for using profanelanguage. There are other threads here to discuss about your emotional state but please refrain from doing so here. Cry me a river!!!!

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41
(@skin-pessimist)

Posted : 08/01/2020 12:33 am

Typically, scars are permanent and hair follicles don't regenerate, but there was one study involving acne scars where some scars went away on their own (IIRC). Does anyone know the study I'm referring to or have a link? I tried looking for the study recently but couldn't locate it

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0
(@Anonymous)

Posted : 08/01/2020 2:00 am

It seems it is possible to trigger some hair growth in some cases through laser. I have had Pulse Dye Laser and that triggered a tiny amount of vellus hair on my burn scar. I've seen a couple of videos from a Korean burn doctor on YouTube who has triggered hair growth while remodelling scars, but this doesn't seem to be the norm. I think it really depends on the level of damageif the folliclecan be stimulated again. If I look at my burn it's pretty much entirely smooth no pores at all, just a flat reflective surface.

 

 

 

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21
(@armanilko)

Posted : 08/01/2020 4:27 am

8 hours ago, gantz said:

can you write theiremail?

Their email address? Sure.

If you want to contact Anthony Weiss (who created elastagen https://en.wikipedia.org/wiki/Anthony_S._Weiss) it's this one: tony.weiss@sydney.edu.au

If you want to contact Rob Daniels (ex CEO of Elastagen before it was acquired by allergan) it's this one: [email protected]

Just a tip: if you ask them when the product will be out, you won't get an answer, as they're both under a NDA, which is a very common thing.

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