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@Tom_Mason Could you add a line somewhere, to show people that we now have at least a treatment for one of the skin scarring conditions out there (stretch marks) thanks to elastagen? If I understood well, we're still not quite there yet when it comes to acne scars, atrophic scars and hypertrophic scars, if I read what @goblue1996 wrote correctly
41 minutes ago, voulzeyes said:@Tom_Mason Could you add a line somewhere, to show people that we now have at least a treatment for one of the skin scarring conditions out there (stretch marks) thanks to elastagen? If I understood well, we're still not quite there yet when it comes to acne scars, atrophic scars and hypertrophic scars, if I read what @goblue1996 wrote correctly
Not sure what I said, you might be mistaking it for what lehran said. Anyway, I feel like we cant say theres treatment until its actually available
12 hours ago, rockginger said:About sunogel I have some bad news, this guy dr sun came back to china recently, he is planning to get a crew of people continue on his research at heibei university where is a middle -class university in china. Im afraidhe maybe a fraud.
sorry for my english, its shity
Source ?
On 3/27/2020 at 8:30 PM, lehran said:Yea, product approval is the tricky part most of the time in these cases. I noticed the same thing you did concerning the product pipeline btw, but I don't think it's that big of a deal: imo it would definitely be easier to created an injectable for acne scars than stretch marks, and with striae being so incredibly common (70-80% of the population) they probably want to be 100% sure that they have something working before indicating it in the pipeline.
I kinda managed to calm down about my stretch marks recently though. Mine are really your typical stretch marks, which I got from growing up a bit too fast (0.1-0.3 mm wide, and a few centimeters long, for the vast majority of them) and they're literally nothing compared to the giant ones that some people got from using steroids :
Only open these links if you have a strong stomach by the way.
I'll be super happy when the treatment will finally be available, but honestly I realized that my little stretch marks are not that big deal at all, at the end of the day. So I'll be ok in the meantime 😉
I can see these are stretch marks, but they are more like scars these ones. You can tell the epidermis has been broken too on most of them.
On 3/25/2020 at 8:55 PM, OddMarket said:https://clinicaltrials.gov/ct2/show/NCT03056235
Elastagens clinical trials for the treatment of atrophic rolling scars with tropoelastin.
Conducted by Hammersmith Medicines Research in the UK. The results were not published, maybe because of the buy out by Allergen?
It should be noted that exclusion criteria included patients with "predominantly box scars or icepick scars".
Suggesting efficacy as a filler but not for scar revision?Maybe further information can be obtained from "Frans van den Berg" email [email protected]
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/elapr002-implant-for-acne-scars-safety-and-efficacy-v1/
Because elastogen is a product that needs to work within a tissue, it doesnt create tissue. Box scars etc if you think about it would need to be revised so its a smooth surface, before elastogen can remodel it. You cant make the tissue grow upwards or tissue that doesnt exist suddenly appear. Rolling scars have the tissue.
12 minutes ago, nikki_gargin said:I can see these are stretch marks, but they are more like scars these ones. You can tell the epidermis has been broken too on most of them.
Because elastogen is a product that needs to work within a tissue, it doesnt create tissue. Box scars etc if you think about it would need to be revised so its a smooth surface, before elastogen can remodel it. You cant make the tissue grow upwards or tissue that doesnt exist suddenly appear. Rolling scars have the tissue.
Makes sense: it provides the molecule which will help the body create lacking skin
24 minutes ago, nikki_gargin said:Elastogen wont take long to come out. 5 years maybe. Its going to make them too much money to wait about.
God I hope not 5 years lol. It's obviously not that long in the grand scheme of things but I'm hoping for sooner still. But if it can't help box scars I'm left waiting anyway I guess
1 hour ago, nikki_gargin said:Elastogen wont take long to come out. 5 years maybe. Its going to make them too much money to wait about.
Word from the dermatologists and surgeons I talked to is something like 2-3 years on average, 5 years is possible, but that's if we're unlucky.
57 minutes ago, lehran said:Word from the dermatologists and surgeons I talked to is something like 2-3 years on average, 5 years is possible, but that's if we're unlucky.
With clinical trials already having occurred I don't see how it could still take that long to come out. I guess they would know better than me tho lol. The sound cloud interview you linked with Dr. Weiss had him saying that the first products would be on the shelf in a year to 18 months, and the interview was 9 months ago already.
33 minutes ago, goblue1996 said:With clinical trials already having occurred I don't see how it could still take that long to come out. I guess they would know better than me tho lol. The sound cloud interview you linked with Dr. Weiss had him saying that the first products would be on the shelf in a year to 18 months, and the interview was 9 months ago already.
They already have a product out there called "Me-tro" for wounds:
Thing is, now that Abvie and allergan have the product, they're gonna make sure it's as profitable and marketable as possible, although they're followin the recommendations of the elastagen team. So yeah it's definitely gonna take some time yet. You're not gonna see it coming out in 2020 or even 2021 imo...but 2022 is definitely a possibilty, we shall see.
2 hours ago, ermete55 said:Does elastogen remove stretchmarks completly?
The synthetic skin completely covers the zones devoid of skin, yes (so basically your stretch marks are filled and replaced with new skin), with the depression volume being reduced by 80-90%: which means that the depth of the depression is reduced by the aforementioned percentage.
So basically, you're going to get healthy looking skin back again, but it's not gonna completely make the depression disappear. For example, let's say you have a stretch mark with a depression depth of 5 millimeters (which is extremely deep for a stretch mark). With this product you're going to get a depression of 1 millimeters, as the new skin will fill it up to 80% (tell me if I'm being clear or not, I had a hard time understanding it the first time I was told lol)
nb: it's elastagen
10 hours ago, Scarcure said:Source ?
http://rczp.hbu.edu.cn/info_show.asp?infoid=260
I dont know why dr sun came back to china. i wonder prospects maybe not so well.
4 hours ago, lehran said:The synthetic skin completely covers the zones devoid of skin, yes (so basically your stretch marks are filled and replaced with new skin), with the depression volume being reduced by 80-90%: which means that the depth of the depression is reduced by the aforementioned percentage.
So basically, you're going to get healthy looking skin back again, but it's not gonna completely make the depression disappear. For example, let's say you have a stretch mark with a depression depth of 5 millimeters (which is extremely deep for a stretch mark). With this product you're going to get a depression of 1 millimeters, as the new skin will fill it up to 80% (tell me if I'm being clear or not, I had a hard time understanding it the first time I was told lol)
nb: it's elastagen
if elastagen could do such improvement about stretch mark, i really have faith about this product that could heal scar very well. cross finger, please come as soon as possible.
8 hours ago, rockginger said:http://rczp.hbu.edu.cn/info_show.asp?infoid=260
I dont know why dr sun came back to china. i wonder prospects maybe not so well.
if elastagen could do such improvement about stretch mark, i really have faith about this product that could heal scar very well. cross finger, please come as soon as possible.
Ok , but how does this make him out to be a fraud if he's recruiting ?.
11 hours ago, ermete55 said:How does it work? It's a injectable or a gel?
It's an injectable solution based on tropoelastin basically. I linked a video with the "metro" gel before, this will give you a good idea of how this is gonna work
8 hours ago, rockginger said:if elastagen could do such improvement about stretch mark, i really have faith about this product that could heal scar very well. cross finger, please come as soon as possible.
They want to treat acne scars and atrophic scars in general, and even hytrophic scars later on. It's just that box scars and icepick scars (acne) are harder to treat, so it'll take slightly more time for that, and I think someone else mentioned this as well. Hypertrophic scars are the real hard thing to take care of, because it's a surplus of skin, it's raised skin, which makes it trickier to remove.
21 minutes ago, Scarcure said:Ok , but how does this make him out to be a fraud if he's recruiting ?.
Because it's a shit tier university probably. If this was the real deal, he'd go to universities like Tsinghua.
NB: @goblue1996 btw, about what we were talking about yesterday: I never managed to get a hint from one of the guys of elastagen as to when the product will launch, I'm just guessing based on what other dermatologists/surgeons say. If you actually manage to find out, god I'm interested xD
I'm not sure i would call Guoming Sun a fraud. He can be cited at John Hopkins University as far back as 2010 where he conducted research on hydrogels with associate professor Sharon Gerecht.
He has filed a number of patents and he's name appears in numerous publications. There is of course a big step between research in the laboratory and a product in the market place.
https://engineering.jhu.edu/magazine/2013/07/healing-wonders-hydrogel/#.XoJCnohKgdV
4 hours ago, ajaxz said:My stretch marks depresses my so deeply that i was going to tattoo all over them this year, hearing those news makes me want to wait
what do i do now?
Just wait, like me. EVERYONE has stretch marks (80% of us), even men (I'm a guy). Mine are your regular stretch marks (they're not too big), but I got them on all my joints from puberty and I'm very self conscious about them, so I know where you're coming from. No one's going to care about yours since most people get them.
Tatooing over stretch marks is a very bad idea, just wait for elastagen to launch its product. I've been doing tons of personal research on them: if they're not the ones who have the solution for striae in the next 2-3 years, I really don't know who else would.
2 hours ago, ermete55 said:Does elastagen change the texture color of the stretchmarks? The akin will tan again?
All your answers are in this document, page 18 (elastagen)
https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf&sa=U&ved=2ahUKEwiT7JGcwcPoAhWM3YUKHQJ7D3MQFjAAegQIBRAB&usg=AOvVaw3h4bM8A_OdyeQkAFgahTh t" rel="external nofollow"> https://www.google.com/url?q=https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf&sa=U&ved=2ahUKEwiT7JGcwcPoAhWM3YUKHQJ7D3MQFjAAegQIBRAB&usg=AOvVaw3h4bM8A_OdyeQkAFgahTht