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1 minute ago, ecek said:this year, I want to get skin color tattoo over my stretch marks. I read it, but not sure I understand it. Even it fills the depressed volume, if it is not heal perfectly, then it wont be a color match. I am really confused. how would effect the tratment if I get the skin color tattoo ?
Why do you keep talking about t he color? If your stretch marks are old, they're either completely white or silvery with a very pale purple tone, like those (you got both cases in the picture below). Once they're in this state, it means they're not gonna evolve anymore.
The slightly discolored or silvery aspect of stretch marks is due to the depression , which creates a "relief", and you probably notice it when you look at them from the sides. So basically, once you'll get renewed skin, you'll get the color of the synthetic skin, which will obviously be of the same color than your basic skin because what tropoelastin does is stimulate the creation of elastin fibers (and, I'm sure you'll agree, it would be weird if your own organism was to create black-colored skin if you're white, or the other way around).
Tattooing over stretch marks, in most cases, is really not a good idea: you can get additional scaring because striae-affected skin is more fragile, the ink might not blend properly AND, most importantly, it's not gonna change a damn thing about their depressed aspect. I have several friends who tried to hide their stretch marks (both males and females) and they all ended up regretting it.
TLDR: be patient, wait a couple years.
3 hours ago, lehran said:Why do you keep talking about t he color? If your stretch marks are old, they're either completely white or silvery with a very pale purple tone, like those (you got both cases in the picture below). Once they're in this state, it means they're not gonna evolve anymore.
The slightly discolored or silvery aspect of stretch marks is due to the depression , which creates a "relief", and you probably notice it when you look at them from the sides. So basically, once you'll get renewed skin, you'll get the color of the synthetic skin, which will obviously be of the same color than your basic skin because what tropoelastin does is stimulate the creation of elastin fibers (and, I'm sure you'll agree, it would be weird if your own organism was to create black-colored skin if you're white, or the other way around).
Tattooing over stretch marks, in most cases, is really not a good idea: you can get additional scaring because striae-affected skin is more fragile, the ink might not blend properly AND, most importantly, it's not gonna change a damn thing about their depressed aspect. I have several friends who tried to hide their stretch marks (both males and females) and they all ended up regretting it.
TLDR: be patient, wait a couple years.
± tried lots of treatments for my stretch marks and it really helped a lot , ( recosma laser and pbserum )therefore now there is no depression. the only problem is the color. Thats why I am considering it.
15 hours ago, lehran said:I can link you literally all the interesting sources I got about elastagen if you want. I got them all bookmarked, there must be 20 of them or so. There are much more out there obviously but those seemed good to me at the very least
Feel free to DM every link you've got lol
9 hours ago, ecek said:i tried lots of treatments for my stretch marks and it really helped a lot , ( recosma laser and pbserum )therefore now there is no depression. the only problem is the color. Thats why I am considering it.
I've got stretch markson my back, buttocks and thighs. The consequences of growing up too fast in my teens. As a guy, I don't really care about them. They are hardly noticeable and 99% of humanity has them. I have noticed them onevery single girl I've dated. Obviously, they hide them with temporary tattoos, permanent ink or other beauty products. They are led to believe that guys are looking for perfection. I have seen severe striae on many people also and I can only imagine the distress you may feel if you are one of them. Just trying to cheer you up.
17 hours ago, lehran said:I can link you literally all the interesting sources I got about elastagen if you want. I got them all bookmarked, there must be 20 of them or so. There are much more out there obviously but those seemed good to me at the very least.
@ermete55 It's probably going to be better than that, but it's gonna take longer to come out than the product they have for stretch marks and acne scars (AND, like others mentioned, they're still going to need on box scars and ice pick scars)
This is from 2017, before they were bought by Allergan/Abbvie
"The companys first target was the medical-aesthetics market. Daniels thought that, with enough funding, it could develop more than one formulation in a reasonable time frame. The company now has products that target three main indications. The most advanced is an injectable gel that makes stretch marks and acne scars fade away. Another is for surgi-cal scars and will be co-developed with a global medical-devices company that has established marketing and sales channels in numerous countries. The third application is in wound repair"
There are lots of products out there that fade away scars including lasers, fillers and heat devices. Women use all kinds of beauty products to cover them up. How would tropoelastin be any different? I have been an active member here for some time posting about new anti-scarring creams, topicals, injectables and drugs in development. I also posted about Tropoelastin back in 2016.
I was misled by many of the researchers' claims on several of these products. I also have read lots of publications on scarless healing. Yet, we are really far away from complete skin regeneration. We are only starting to understand the mechanics behind our body's biggest organ.
I have high hopes on tropoelastin just like FS2 and OLX101. However, a long time will be required before a more succesful treatment for scarring will be marketed.
1 hour ago, MyBeautifulScars said:I've got stretch markson my back, buttocks and thighs. The consequences of growing up too fast in my teens. As a guy, I don't really care about them. They are hardly noticeable and 99% of humanity has them. I have noticed them onevery single girl I've dated. Obviously, they hide them with temporary tattoos, permanent ink or other beauty products. They are led to believe that guys are looking for perfection. I have seen severe striae on many people also and I can only imagine the distress you may feel if you are one of them. Just trying to cheer you up.
There are lots of products out there that fade away scars including lasers, fillers and heat devices. Women use all kinds of beauty products to cover them up. How would tropoelastin be any different? I have been an active member here for some time posting about new anti-scarring creams, topicals, injectables and drugs in development. I also posted about Tropoelastin back in 2016.
I was misled by many of the researchers' claims on several of these products. I also have read lots of publications on scarless healing. Yet, we are really far away from complete skin regeneration. We are only starting to understand the mechanics behind our body's biggest organ.
I have high hopes on tropoelastin just like FS2 and OLX101. However, a long time will be required before a more succesful treatment for scarring will be marketed.
Tropoelastin seems different because our bodies need it to properly heal but we don't make a lot of it. Plus the technology seems different than the other ones you listed because it has had several human trials conducted and Allergan then spent hundred of millions of dollars to acquire it. Allergan wasn't looking to waste massive amounts of money for something that didn't show signs of beingtruly different.
Since @goblue1996asked me, I'm sharing all the good links I could find so far with you guys (there are way more, but the others don't add anything really interesting imo). For the afr.com links you just have to stop the loading page at the right moment, and you won't have to pay anything to read the entire articles.
I/ You wanna take a look at the original elastagen website first: http://elastagen.com /" rel="external nofollow"> https://web.archive.org/web/20190423230745/http://elastagen.com/
II/Here are the links:
https://en.wikipedia.org/wiki/Anthony_S._Weiss
https://www.tbt.wiki/post/3701560856285543276225
https://www.nature.com/articles/545S21a.pdf?draft=marketing
https://www.linkedin.com/pulse/allergan-acquire-elastagen-access-next-generation-injectable-weiss/
https://www.mtaa.org.au/sites/default/files/uploaded-content/field_f_content_file/anthony_weiss.pdf
https://2019.biomaterials.org/sites/default/files/abstracts/273.pdf
https://www.medicalresearch.nsw.gov.au/human-skin-replacement-that-got-experts-buzzing/
https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf
http://www.ipaustralia.com.au/applicant/elastagen-pty-ltd/patents/AU2007321701/
http://www.cell-ip.com/en/images/180424_Elastagen Exit_E_final.pdf
https://www.utahfacialplastics.com/2018/03/08/allergan-acquires-elastin-more-juvederm-products/
https://www.spaandclinic.com.au/business/allergan-buys-university-sydneys-elastagen-120-mio
https://micro.org.au/innovation/fast-tracking-elastin-to-market/
https://www.businessinsider.com.au/botox-maker-allergan-buys-elastagen-2018-2
https://www.pharmasalmanac.com/articles/allergen-acquires-elastagen
https://www.globallegalchronicle.com/allergans-acquisition-of-elastagen/
https://2019.biomaterials.org/sites/default/files/abstracts/273.pdf
III/ And do listen to this
On 3/23/2020 at 6:23 AM, nikki_gargin said:
Did they say 1.5mm too big or your opinion? 1.5 round hollow needle is not big? How is that too big to work on single acne scars? In my mind the technique works by scarless wound contraction. So I just cant imagine how thats too big thats why Im so interested.
Sorry for late reply on Microcoring
All she said was sizes less than 0.5mm were in the safe zone.
Can someone explain how Tropoelastin can help improve/remove scar texture and possibly restore normal texture.Im talking about the surface texture for a small scar that isn'tdepressed. And what is the application for treating such a scar if it can restore texture. Or is it only helpful in restoring volume?
On 4/1/2020 at 4:14 AM, MyBeautifulScars said:I have seen severe striae on many people also and I can only imagine the distress you may feel if you are one of them
Just curious: when you are talking about severe ones what do you mean? Imo anything that is between 1 millimeter to maximum 1 centimeters large is standard (normal stretch marks from puberty, pregnancy etc..) but anything bigger than that is severe. I'm saying that because even though a 1mm wide striae might be considered as big for some, it really isn't when compared to people who get stretch marks which are sometimes 4-5 centimers wide or more
On 4/10/2020 at 7:15 AM, lehran said:Just curious: when you are talking about severe ones what do you mean? Imo anything that is between 1 millimeter to maximum 1 centimeters large is standard (normal stretch marks from puberty, pregnancy etc..) but anything bigger than that is severe. I'm saying that because even though a 1mm wide striae might be considered as big for some, it really isn't when compared to people who get stretch marks which are sometimes 4-5 millimeters wide
This is what can be classified as severe striae.
4 hours ago, MyBeautifulScars said:This is what can be classified as severe striae.
Yeah, those are quite big for sure. I have seen some people with those, and most of the time they're cause by stuff like prednisone. In comparison, normal stretch marks really aren't a big deal at all.
I wonder why they don't communicate more about this though: if they finally have a solution for stretch marks, then they're the only ones with a proper answer to an unsatisfied market worth billions of dollars...or maybe it's not time yet because they have yet to find the proper way of making it work? If it was ready we'd have "before/after" pictures right now.
I sent a mail to allergan and abbvie, telling them that I heard about elastagen, and that I volunteered to be part of any clinical trial phase that would occur for stretch marks. I don't know if they'll be interested, but I'll keep you guys updated.
7 hours ago, voulzeyes said:I wonder why they don't communicate more about this though: if they finally have a solution for stretch marks, then they're the only ones with a proper answer to an unsatisfied market worth billions of dollars...or maybe it's not time yet because they have yet to find the proper way of making it work? If it was ready we'd have "before/after" pictures right now.
I think it might just be a marketing thing right now. Releasing good before and after photos would get a lot of people interested in the product and trying to find a way to buy it. If you release pictures a couple years before launch then you let the hype die down and some people will inevitably forget about the product when it finally launches and not seek treatment. There's really no point to release the photos if they're goodin advanceof launch; other than giving people hope. Idon't think Allergan really cares that much about giving hope tho; just that they make some money off of us lol.
5 minutes ago, goblue1996 said:I think it might just be a marketing thing right now. Releasing good before and after photos would get a lot of people interested in the product and trying to find a way to buy it. If you release pictures a couple years before launch then you let the hype die down and some people will inevitably forget about the product when it finally launches and not seek treatment. There's really no point to release the photos if they're good in advance of launch; other than giving people hope. I don't think Allergan really cares that much about giving hope tho; just that they make some money off of us lol.
I have a hard time believing that, once people find out that a product will be there to erase stretch marks, the hype could die down even 3 years after the announcement 
13 hours ago, voulzeyes said:I have a hard time believing that, once people find out that a product will be there to erase stretch marks, the hype could die down even 3 years after the announcement
Like you said, it has nothing to do with the hype going down like you said. If one of the biggest pharmaceutical companies in the world (abbvie) say that they finally have the solution for stretch marks, and that we only have to wait a few years, you can be damn sure that the hype won't die, it will actually slowly build over the years.
The reason we still haven't heard about them is because they're still figuring out the best way to make this work for stretch marks: what kind of injectable, should they use hyaluronic acid as a complement, should they blablabla...they got the right product (tropoelastin) but now they need to implement it properly. That's why it's going to take a couple years imo.
5 minutes ago, rock123456 said:any news about micro coring?
micro coring is designed to reduce skin. so this device must be working on scar, right? I found micro coring had been clinical trials about acne scars. but nothing about results. does anybody have any resources about that.
I've heard about it, but there doesn't seem to be any major breakthrough yet, we'll probably have to wait some more.
21 hours ago, lehran said:I've heard about it, but there doesn't seem to be any major breakthrough yet, we'll probably have to wait some more.
they announced will sell products in this year or next year on interview from youtube videos. I think some treatment's pics should be published. I mean at least they should tell us how good it will be before selling it, right?
Guys, I really want to hear about this elastagen stuff for my stretch marks. They're not severe or anything, but I can't wait to get rid of them, this is going to be a huge confidence booster for me. Should I contact Abbvie, Allergan or something to get proper news. We don't know when this is coming or anything so it's super tough to wait like this.
On 4/16/2020 at 5:14 AM, lehran said:Polarityte is still working on their product, never heard about the other two
Polarity SkinTE was a scam and the founders left quickly,likely jeopardized their medical careers in the longrun. At some point, the new startup was merged with a bankrupt video game company and investors were fooled into buying stock quickly. The new entity eventually was the target of multiple criminal allegations which affected the market stock value. Eventually, new researchers took over and presently believe they canturn things around.
About two years ago, Polaritystarted releasing clinical resultsincluding picsafter so called successfultrials which didn't live up to the potential hype they created themselves. The shots were actually posted here a few years back which everyone could see by scrolling back through the pages. A lot of posters had lots of faith in this product, but were let down.It wasn't scarless healing. Many of them have now dissapeared and have created hidden forums which we are not invited to join.
Polarity made those pics public for everyone to see on their website. Unfortunately since the new ownership came in, they have taken them down. Sorry to burst your bubble, but Polarity's potential at this point is nothing more than an alternative to skin grafts. Scars will form after healing even when this product is applied on the wound. Scarring may be less severe but will still be present. Also, it seems lots of patients with compromised immune systems were prone to infections which is quite normal. Our bodies scar to close wounds quickly and applying some paste made of stem cells will interfere with the natural healing process. SkinTE is not for everyone.
8 hours ago, MyBeautifulScars said:Polarity SkinTE was a scam and the founders left quickly,likely jeopardized their medical careers in the longrun. At some point, the new startup was merged with a bankrupt video game company and investors were fooled into buying stock quickly. The new entity eventually was the target of multiple criminal allegations which affected the market stock value. Eventually, new researchers took over and presently believe they canturn things around.
About two years ago, Polaritystarted releasing clinical resultsincluding picsafter so called successfultrials which didn't live up to the potential hype they created themselves. The shots were actually posted here a few years back which everyone could see by scrolling back through the pages. A lot of posters had lots of faith in this product, but were let down.It wasn't scarless healing. Many of them have now dissapeared and have created hidden forums which we are not invited to join.
Polarity made those pics public for everyone ro see on their website. Unfortunately since the new ownership came in, they have taken them down. Sorry to burst your bubble, but Polarity's potential at this point is nothing more than an alternative to skin grafts. Scars will form after healing even when this product is applied on the wound. Scarring may be less severe but will still be present. Also, it seems lots of patients with compromised immune systems were prone to infections which is quite normal. Our bodies scar to close wounds quickly and applying some paste made of stem cells will interfere with the natural healing process. SkinTE is not for everyone.
Interesting, thank you for your input. I stopped caring about them entirely when I learned from a surgeon that their product would do nothing for stretch marks anyways(and elastagen seems to have the solution for striae)so you're not bursting my bubble or anything, but still that sucks for all the people who were hoping for something to happen. What hope is left for scars except elastagen now? I've already read someone say that sunogel was a failure on this forum, which would mean that people with scars are two options short
Here's a link I found that talks about elastagen briefly that I don't think lehran posted before. It just talks about the results of the acne scar trials they ran very briefly:"New topline data was presented on the use of TE-HA, the hydrogel containing recombinant tropoelastin, gained as part of Allergan's acquisition of Elastagen, for the treatment of adult patients with acne scars. At 6 months, 21 of 27 (78%) patients reported improvements in acne scar appearance. TE-HA also demonstrated significant reduction in acne scar depth and volume compared to the control group"
Doesn't really state how significant the improvement was and it's a small sample size obviously, but still seems like reason for some optimism and I'm not sure there's a current treatment out there that can say that over 70% of patients have improvement.
19 hours ago, lehran said:I've already read someone say that sunogel was a failure on this forum
lmao Who? Who said that? It says on Sunogel's site that they've achieved scarless healing, dude. They ain't lying either. At least I don't think so. If you are concerned/curious about them (i.e. Sunogel) send them an e-mail.