2 hours ago, goblue1996 said:Got a link?
I forgot to include it, my bad:
https://clinicaltrials.gov/ct2/show/NCT03056235
Elastagens clinical trials for the treatment of atrophic rolling scars with tropoelastin.
Conducted by Hammersmith Medicines Research in the UK. The results were not published, maybe because of the buy out by Allergen?
It should be noted that exclusion criteria included patients with "predominantly box scars or icepick scars".
Suggesting efficacy as a filler but not for scar revision?
Maybe further information can be obtained from "Frans van den Berg" email [email protected]
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/elapr002-implant-for-acne-scars-safety-and-efficacy-v1/
20 hours ago, OddMarket said:https://clinicaltrials.gov/ct2/show/NCT03056235
Elastagens clinical trials for the treatment of atrophic rolling scars with tropoelastin.
Conducted by Hammersmith Medicines Research in the UK. The results were not published, maybe because of the buy out by Allergen?
It should be noted that exclusion criteria included patients with "predominantly box scars or icepick scars".
Suggesting efficacy as a filler but not for scar revision?Maybe further information can be obtained from "Frans van den Berg" email [email protected]
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/elapr002-implant-for-acne-scars-safety-and-efficacy-v1/
Yeah I had the same worry about it excluding box/ icepick scars. I actually emailed the guy who invented the product, Dr. Weiss, and he was nice enough to respond. Here's what he said: "Our technology should eventually be applicable to other types of acne scars such as boxcar." Obviously a bare bones response and I'm sure he's not allowed to say a whole lot else since the products in development, but I appreciated he took the time to respond at all. Going by what he said. it'll just be a matter of remaining patient.
2 hours ago, goblue1996 said:Yeah I had the same worry about it excluding box/ icepick scars. I actually emailed the guy who invented the product, Dr. Weiss, and he was nice enough to respond. Here's what he said: "Our technology should eventually be applicable to other types of acne scars such as boxcar." Obviously a bare bones response and I'm sure he's not allowed to say a whole lot else since the products in development, but I appreciated he took the time to respond at all. Going by what he said. it'll just be a matter of remaining patient.
Oh, I couldn't get an answer from him so far (I did get one from the ceo though). Would you mind asking him about stretch marks in particular? I know that we have tons of sources where they mention awesome results, but I'd really like to hear what he has to say about it.
20 minutes ago, lehran said:Oh, I couldn't get an answer from him so far (I did get one from the ceo though). Would you mind asking him about stretch marks in particular? I know that we have tons of sources where they mention awesome results, but I'd really like to hear what he has to say about it.
Yep I'll see if I can get him to respond again. I was really surprised he took the time to respond at all to me lol.
59 minutes ago, goblue1996 said:Yep I'll see if I can get him to respond again. I was really surprised he took the time to respond at all to me lol.
Me too man, you're lucky xD
edit: I tried asking him again, you never know.
This is not about acne scars, atrophic scars or hypertrophic scars (gotta say it in order to make sure no one gets hyped for nothing), it's just about stretch marks BUT this is very good news:
I tried to get in touch with Dr Weiss again, asking about tropoelastin, like @goblue1996 did recently, and I managed to get an answer about stretch marks. I'll cut to the chase: my question was simply " does this mean that patients all around the world are soon going to have access to a treatment that will finally bring a viable solution to this very common skin condition"? And as an answer, I didn't get a "maybe", or a "that remains to be seen", but a very clear "yes, we're very optimistic about that. Especially since our technology is now with Allergan, which has recently been bought by Abbvie"...and this, from the guy who actually created the product.
I know it doesn't sound like it's big, but still, the reason why I'm incredibly happy about this is that I've been looking at tons of sources for months (I spent an enormous amount of time looking into this), and despite all the good things that I managed to find, getting a proper "yes" from him is extremely reassuring: I know I can patiently wait for this to come out now, without being worried about the outcome.
That's just for stretch marks though, but maybe Goblue will get some interesting answers about other types of scarring.
TLDR: when it comes to stretch marks, we got a YES boys!
I hope you guys are doing alright with the whole covid-19 thingy.
See y'all 😉
34 minutes ago, lehran said:I know it doesn't sound like it's big, but still, the reason why I'm incredibly happy about this is that I've been looking at tons of sources for months (I spent an enormous amount of time looking into this), and despite all the good things that I managed to find, getting a proper "yes" from him is extremely reassuring: I know I can patiently wait for this to come out now, without being worried about the outcome.
Don't understate it, it'ssounds like abig deal. Once the product starts bringing in some revenue,you know Abbvie will start to see what else it can help treat. The hardest part I would think is getting the product approved. Once it is, then you can easily test it for all sorts of stuff.
I noticed on Allergens website they have a product pipeline page saying what they are developing. It mentions Elastagen for skin quality and acne scars, but no mention for specifically stretch marks. Kinda curious why it doesn'tif Dr. Weiss is so sure it's gonna work great. Anyway it's great news for people like you. Fingers crossed it'll work as good for acne scars lol
Also... he didn't happen to mention timeline for product launch did he? I'm assuming he didn't but i guess ya never know.
23 minutes ago, goblue1996 said:Don't understate it, it'ssounds like abig deal. Once the product starts bringing in some revenue,you know Abbvie will start to see what else it can help treat. The hardest part I would think is getting the product approved. Once it is, then you can easily test it for all sorts of stuff.
I noticed on Allergens website they have a product pipeline page saying what they are developing. It mentions Elastagen for skin quality and acne scars, but no mention for specifically stretch marks. Kinda curious why it doesn'tif Dr. Weiss is so sure it's gonna work great. Anyway it's great news for people like you. Fingers crossed it'll work as good for acne scars lol
Yea, product approval is the tricky part most of the time in these cases. I noticed the same thing you did concerning the product pipeline btw, but I don't think it's that big of a deal: imo it would definitely be easier to created an injectable for acne scars than stretch marks, and with striae being so incredibly common (70-80% of the population) they probably want to be 100% sure that they have something working before indicating it in the pipeline.
I kinda managed to calm down about my stretch marks recently though. Mine are really your typical stretch marks, which I got from growing up a bit too fast (0.1-0.3 mm wide, and a few centimeters long, for the vast majority of them) and they're literally nothing compared to the giant ones that some people got from using steroids :
Only open these links if you have a strong stomach by the way.
I'll be super happy when the treatment will finally be available, but honestly I realized that my little stretch marks are not that big deal at all, at the end of the day. So I'll be ok in the meantime 😉
7 minutes ago, lehran said:Yea, product approval is the tricky part most of the time in these cases. I noticed the same thing you did concerning the product pipeline btw, but I don't think it's that big of a deal: imo it would definitely be easier to created an injectable for acne scars than stretch marks, and with striae being so incredibly common (70-80% of the population) they probably want to be 100% sure that they have something working before indicating it in the pipeline.
I kinda managed to calm down about my stretch marks recently though. Mine are really your typical stretch marks, which I got from growing up a bit too fast (0.1-0.3 mm wide, and a few centimeters long, for the vast majority of them) and they're literally nothing compared to the giant ones that some people got from using steroids :
Only open these links if you have a strong stomach by the way.
I'll be super happy when the treatment will finally be available, but honestly I realized that my little stretch marks are not that big deal at all, at the end of the day. So I'll be ok in the meantime 😉
Fuck me, I didn't know you could get this from steroids...
1 hour ago, lehran said:I'll be super happy when the treatment will finally be available, but honestly I realized that my little stretch marks are not that big deal at all, at the end of the day. So I'll be ok in the meantime 😉
I get into thismindset that my scars aren't that bad and everything will be okay, just to end up thinking they're the worse thing ever a few months later lol. The back and forth of it all can be so draining. glad to hear you've made piece with yours tho and even so treatment is likely on the way.
11 minutes ago, goblue1996 said:I get into thismindset that my scars aren't that bad and everything will be okay, just to end up thinking they're the worse thing ever a few months later lol. The back and forth of it all can be so draining. glad to hear you've made piece with yours tho and even so treatment is likely on the way.
Stay away from bright artificial lights and you'll be ok, they make them look 10 times worse than what they're really like. Been there, done that.
I'm not going to lie though: knowing that the first real treatment ever for SM is coming in a couple of years is helping a lot.
On 3/2/2020 at 12:07 AM, AlexZ77 said:Ye lehran chill put bro, any of these treatments could cause a evolution in skin regeneration, Sunogel might take it a bit longer but its definitely not the next shity SkinTE company
if sunogel wont relase anything new within the next 2 years then we can be sure
About sunogel I have some bad news, this guy dr sun came back to china recently, he is planning to get a crew of people continue on his research at heibei university where is a middle -class university in china. Im afraidhe maybe a fraud.
sorry for my english, its shity
2 hours ago, rockginger said:About sunogel I have some bad news, this guy dr sun came back to china recently, he is planning to get a crew of people continue on his research at heibei university where is a middle -class university in china. Im afraidhe maybe a fraud.
sorry for my english, its shity
If true that's too bad. Although it seemed like not much progress was being made on the product anyway so I wasn't getting my hopes up for Sunogel anyway.
3 hours ago, goblue1996 said:If true that's too bad. Although it seemed like not much progress was being made on the product anyway so I wasn't getting my hopes up for Sunogel anyway.
Sunogel wasso amazing when the videos came out. i was so sure about this gel could be something. very sad
7 hours ago, rockginger said:About sunogel I have some bad news, this guy dr sun came back to china recently, he is planning to get a crew of people continue on his research at heibei university where is a middle -class university in china. Im afraidhe maybe a fraud.
sorry for my english, its shity
There were red flags everywhere honestly, it's not surprising at all. That's why I think that managing our expectations is always the best thing to do.
Again, I wasn't able to find a single thing about sunogel that was reassuring or noteworthy.
@Tom_Mason Could you add a line somewhere, to show people that we now have at least a treatment for one of the skin scarring conditions out there (stretch marks) thanks to elastagen? If I understood well, we're still not quite there yet when it comes to acne scars, atrophic scars and hypertrophic scars, if I read what @goblue1996 wrote correctly
41 minutes ago, voulzeyes said:@Tom_Mason Could you add a line somewhere, to show people that we now have at least a treatment for one of the skin scarring conditions out there (stretch marks) thanks to elastagen? If I understood well, we're still not quite there yet when it comes to acne scars, atrophic scars and hypertrophic scars, if I read what @goblue1996 wrote correctly
Not sure what I said, you might be mistaking it for what lehran said. Anyway, I feel like we cant say theres treatment until its actually available
12 hours ago, rockginger said:About sunogel I have some bad news, this guy dr sun came back to china recently, he is planning to get a crew of people continue on his research at heibei university where is a middle -class university in china. Im afraidhe maybe a fraud.
sorry for my english, its shity
Source ?
On 3/27/2020 at 8:30 PM, lehran said:Yea, product approval is the tricky part most of the time in these cases. I noticed the same thing you did concerning the product pipeline btw, but I don't think it's that big of a deal: imo it would definitely be easier to created an injectable for acne scars than stretch marks, and with striae being so incredibly common (70-80% of the population) they probably want to be 100% sure that they have something working before indicating it in the pipeline.
I kinda managed to calm down about my stretch marks recently though. Mine are really your typical stretch marks, which I got from growing up a bit too fast (0.1-0.3 mm wide, and a few centimeters long, for the vast majority of them) and they're literally nothing compared to the giant ones that some people got from using steroids :
Only open these links if you have a strong stomach by the way.
I'll be super happy when the treatment will finally be available, but honestly I realized that my little stretch marks are not that big deal at all, at the end of the day. So I'll be ok in the meantime 😉
I can see these are stretch marks, but they are more like scars these ones. You can tell the epidermis has been broken too on most of them.
On 3/25/2020 at 8:55 PM, OddMarket said:https://clinicaltrials.gov/ct2/show/NCT03056235
Elastagens clinical trials for the treatment of atrophic rolling scars with tropoelastin.
Conducted by Hammersmith Medicines Research in the UK. The results were not published, maybe because of the buy out by Allergen?
It should be noted that exclusion criteria included patients with "predominantly box scars or icepick scars".
Suggesting efficacy as a filler but not for scar revision?Maybe further information can be obtained from "Frans van den Berg" email [email protected]
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/elapr002-implant-for-acne-scars-safety-and-efficacy-v1/
Because elastogen is a product that needs to work within a tissue, it doesnt create tissue. Box scars etc if you think about it would need to be revised so its a smooth surface, before elastogen can remodel it. You cant make the tissue grow upwards or tissue that doesnt exist suddenly appear. Rolling scars have the tissue.
12 minutes ago, nikki_gargin said:I can see these are stretch marks, but they are more like scars these ones. You can tell the epidermis has been broken too on most of them.
Because elastogen is a product that needs to work within a tissue, it doesnt create tissue. Box scars etc if you think about it would need to be revised so its a smooth surface, before elastogen can remodel it. You cant make the tissue grow upwards or tissue that doesnt exist suddenly appear. Rolling scars have the tissue.
Makes sense: it provides the molecule which will help the body create lacking skin
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