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I dont know how much more waiting i can take , i got a margin from dry eye .... looks like someone cut my eyelid
I have been battling scars since 18 years old , am going to be 31 in under 3 weeks .... am so depressed my eyes are red from crying , i tried suicide 3 to 4 times because of the scars on my face .... Am weak in this respect , you have to admire the people that are victim of burns and they try to get on.
There's a 6 year old child that was burned from a house fire ..... it breaks my heart seeing her .... but with my depression , ocd , and lack of friends coping is all i can do.
i meditate every morning , i train , i eat right , i try to look at the bright side , but i just see myself 6 feet under ... if i was never cursed with the acne in the first place all this would be prevented.
I hope this decade is it .... because this isn't right for anyone to go though , not just acne scars , but any scarring.
8 hours ago, Scarcure said:I dont know how much more waiting i can take , i got a margin from dry eye .... looks like someone cut my eyelid
I have been battling scars since 18 years old , am going to be 31 in under 3 weeks .... am so depressed my eyes are red from crying , i tried suicide 3 to 4 times because of the scars on my face .... Am weak in this respect , you have to admire the people that are victim of burns and they try to get on.
There's a 6 year old child that was burned from a house fire ..... it breaks my heart seeing her .... but with my depression , ocd , and lack of friends coping is all i can do.
i meditate every morning , i train , i eat right , i try to look at the bright side , but i just see myself 6 feet under ... if i was never cursed with the acne in the first place all this would be prevented.
I hope this decade is it .... because this isn't right for anyone to go though , not just acne scars , but any scarring.
You sound quite familiar of someone I know. Where are you located?
15 hours ago, Valkyros said:Nah, I'm not going to do that. First, putting pigments on stretch marks is not a good idea in general, in the long-term, and it doesn't really address the problem that much, imo.
I might have considered it if no good option was in sight, but with elastagen having developed a proper product for filling the void of stretch marks with synthethic skin, I can wait a few years honestly.
I am still quite eerieabout introducing something synthetic inside the largest organ of my body:
1)firstly on the bed of an open wound and 2)secondly leavingit inside theskin as the wound contracts.
I wonder if this product gets eventually absorbed by the body and wether it has carcinogenic or other health effects in the longrun. Is this manufactured thin layer free of all contaminents that may be life-threatening? What happens if the wound gets infected afterthe material gets placed?
SkinTE is complete hogwash for scars. They cut pieces of skin, make a paste and put it on the wound. Congratulations, now you have 2 scars instead of 1. The only discipline it can be useful for is possibly burns. Those stem cells in that paste may minimize scarring to a certain degree. If anyone goes back a few pages onthis thread, patient pictures under clinical trials usingthe revolutionary SkinTE technology have been posted. It is not scar-free, scarless or complete regeneration as you may wish to call it. Is the scarring minimized? Yes to some degree. Moving along.
There were a few topicals that I had discussed under clinical trials a few years back. I had really high hopes particularly on BirchBiomed's FS2. Unfortunately, we haven't heard anything from themafter they commenced their second clinical trial stage, which was about 2 years ago. I no longer feel enthusiastic that they will ever release anything to market in the foreseeable future.
Another offshoot was OLX101. This startup apparently discovered a way of transforming RNAreverting existing scars to normal skin and preventing new ones from forming. Quite innovative, their methodology involves gene sequencing and scars dissapear with a simple injection. Unfortunately, as many other proponents, they vanish several years later after initially releasing forward looking statements.
For scarless healing to be achieved, I have realized it can only happen under the following circumstance. Let me elaborate further. I personally believe scar reduction or formation will and must be achieved through a topical or injectable plasma like material. Our bodies have evolved to close wounds as quickly as possible to stop infectious agents from spreading. Mammalian evolution came with a major stepback : no complete regeneration in order to reduce microbial disease. A small write-off you may say but in a society were beauty standards are constitantly pushed to new limits, I can understand why everybody is ashamed of their scars, acne and stretch marks.
Let's think for a moment. Messing around with an existing wound is strictly not recommended by all physicians. Best remedy is to wash withwater and let heal. Obviously, when the gap is clearly life-threatening, surgeons will use sutures or own skin grafts to assist the healing process. Constant monitoring is then providedto eliminate contamination for several days to even years. This is why SkinTE poses several serious risks. No credible physician will leave, for example, a 0.5cm wide open wound exposed to apply some magic paste and hope for regeneration. The product is suggested to some patients and a signed waiver is usually requested. Nothing is set in stone yet for SkinTE.Their recent struggles make me question their credibility as a whole.
3 hours ago, MyBeautifulScars said:You sound quite familiar of someone I know. Where are you located?
I am still quite eerieabout introducing something synthetic inside the largest organ of my body:
1)firstly on the bed of an open wound and 2)secondly leavingit inside theskin as the wound contracts.
I wonder if this product gets eventually absorbed by the body and wether it has carcinogenic or other health effects in the longrun. Is this manufactured thin layer free of all contaminents that may be life-threatening? What happens if the wound gets infected afterthe material gets placed?
SkinTE is complete hogwash for scars. They cut pieces of skin, make a paste and put it on the wound. Congratulations, now you have 2 scars instead of 1. The only discipline it can be useful for is possibly burns. Those stem cells in that paste may minimize scarring to a certain degree. If anyone goes back a few pages onthis thread, patient pictures under clinical trials usingthe revolutionary SkinTE technology have been posted. It is not scar-free, scarless or complete regeneration as you may wish to call it. Is the scarring minimized? Yes to some degree. Moving along.
There were a few topicals that I had discussed under clinical trials a few years back. I had really high hopes particularly on BirchBiomed's FS2. Unfortunately, we haven't heard anything from themafter they commenced their second clinical trial stage, which was about 2 years ago. I no longer feel enthusiastic that they will ever release anything to market in the foreseeable future.
Another offshoot was OLX101. This startup apparently discovered a way of transforming RNAreverting existing scars to normal skin and preventing new ones from forming. Quite innovative, their methodology involves gene sequencing and scars dissapear with a simple injection. Unfortunately, as many other proponents, they vanish several years later after initially releasing forward looking statements.
For scarless healing to be achieved, I have realized it can only happen under the following circumstance. Let me elaborate further. I personally believe scar reduction or formation will and must be achieved through a topical or injectable plasma like material. Our bodies have evolved to close wounds as quickly as possible to stop infectious agents from spreading. Mammalian evolution came with a major stepback : no complete regeneration in order to reduce microbial disease. A small write-off you may say but in a society were beauty standards are constitantly pushed to new limits, I can understand why everybody is ashamed of their scars, acne and stretch marks.
Let's think for a moment. Messing around with an existing wound is strictly not recommended by all physicians. Best remedy is to wash withwater and let heal. Obviously, when the gap is clearly life-threatening, surgeons will use sutures or own skin grafts to assist the healing process. Constant monitoring is then providedto eliminate contamination for several days to even years. This is why SkinTE poses several serious risks. No credible physician will leave, for example, a 0.5cm wide open wound exposed to apply some magic paste and hope for regeneration. The product is suggested to some patients and a signed waiver is usually requested. Nothing is set in stone yet for SkinTE.Their recent struggles make me question their credibility as a whole.
Am located in the UK.
7 hours ago, MyBeautifulScars said:I am still quite eerieabout introducing something synthetic inside the largest organ of my body:
1)firstly on the bed of an open wound and 2)secondly leavingit inside theskin as the wound contracts.
I wonder if this product gets eventually absorbed by the body and wether it has carcinogenic or other health effects in the longrun. Is this manufactured thin layer free of all contaminents that may be life-threatening? What happens if the wound gets infected afterthe material gets placed?
SkinTE is complete hogwash for scars. They cut pieces of skin, make a paste and put it on the wound. Congratulations, now you have 2 scars instead of 1. The only discipline it can be useful for is possibly burns. Those stem cells in that paste may minimize scarring to a certain degree. If anyone goes back a few pages onthis thread, patient pictures under clinical trials usingthe revolutionary SkinTE technology have been posted. It is not scar-free, scarless or complete regeneration as you may wish to call it. Is the scarring minimized? Yes to some degree. Moving along.
There were a few topicals that I had discussed under clinical trials a few years back. I had really high hopes particularly on BirchBiomed's FS2. Unfortunately, we haven't heard anything from themafter they commenced their second clinical trial stage, which was about 2 years ago. I no longer feel enthusiastic that they will ever release anything to market in the foreseeable future.
Another offshoot was OLX101. This startup apparently discovered a way of transforming RNAreverting existing scars to normal skin and preventing new ones from forming. Quite innovative, their methodology involves gene sequencing and scars dissapear with a simple injection. Unfortunately, as many other proponents, they vanish several years later after initially releasing forward looking statements.
For scarless healing to be achieved, I have realized it can only happen under the following circumstance. Let me elaborate further. I personally believe scar reduction or formation will and must be achieved through a topical or injectable plasma like material. Our bodies have evolved to close wounds as quickly as possible to stop infectious agents from spreading. Mammalian evolution came with a major stepback : no complete regeneration in order to reduce microbial disease. A small write-off you may say but in a society were beauty standards are constitantly pushed to new limits, I can understand why everybody is ashamed of their scars, acne and stretch marks.
Let's think for a moment. Messing around with an existing wound is strictly not recommended by all physicians. Best remedy is to wash withwater and let heal. Obviously, when the gap is clearly life-threatening, surgeons will use sutures or own skin grafts to assist the healing process. Constant monitoring is then providedto eliminate contamination for several days to even years. This is why SkinTE poses several serious risks. No credible physician will leave, for example, a 0.5cm wide open wound exposed to apply some magic paste and hope for regeneration. The product is suggested to some patients and a signed waiver is usually requested. Nothing is set in stone yet for SkinTE.Their recent struggles make me question their credibility as a whole.
Tons of interesting things were mentioned here, let's see:
I/ About elastagen: it's an interesting thought. And you're quite right when you say that infections could always happen if it's not done right. However, that's only when we're talking about open wounds. When it comes to stuff like stretch marks (which is what is going to interest most people), it's a non-issue imo. If I can get something like a 90% reduction, I'm more than willing to do it, it's going to be way too much of a life change for. Also, I looked into it: there's no way that this will be absorbed by the body, as clinical trials proved that the body is tricked into thinking that it's the original skin = 0 compatibility issues (and ofc, it reproduces every function of the skin, as mentioned here ( https://go8.edu.au/wp-content/uploads/2019/04/Allies-In-Excellence.pdf)
II/About SkinTE: you're dead on man. SkinTE is not going to do jack shit for scars, acne scars, atrophic scars, hypertrophic scars, yada yada...I asked several surgeons/dermatologists, and it's a clear difference when compared to how lauded elastagen's product is right now.
III/Do take a look at what direct biologics is doing with exoflo (since you mentioned birchbiomed and OLX): my surgeon tells me it's very promising for scars and stretch marks.
I'm probably starting to look like a fanboy since I'm always talking about elastagen, but it's just because I'm very careful, probably like you are, with these things: who are the investors, what is the medical team like, how popular is it, what were the clinical trials like, are the big dogs from the pharmaceutical industries interested and so on...
So far, when it comes to tissue regeneration/skin replacement/scar healing, I haven't seen any clinical trial company been bought for hundreds of millions of dollars by a big company except elastagen, so, although I do keep the other names in mind, my bet is on that one for now. Now when it comes to 100% scar healing we're not quite ther yet, but something which will make an extremely big difference (90% reduction, which is what their trials show so far) is more than enough for small scars/skin lesions, as that will allow us to show our skin without feeling bad about it.
I honestly don't get why people act like any human creation is bad for your health. Just because something isn't organic/"natural" doesn't mean it is bad for you. Natural products aren't the solution to our problems. In fact, many natural substances and remedies are complete hogwash without any sort of scientific evidence. There are some exceptions of course, but you get the gist.
Something penetrating the dermis isn't necessarily a bad thing. These sort of products go through clinical testing to ensure their safety. If a new innovation removes or lessens acne scars without severe consequences, then it's something many of us will be excited about. Are scars the worst issue in the world? No. There are many people dealing with much worse things. That doesn't change the reality that human appearance impacts people's perception of you, social outcomes, self esteem, and even quality of life.
16 hours ago, Skin Pessimist said:I honestly don't get why people act like any human creation is bad for your health. Just because something isn't organic/"natural" doesn't mean it is bad for you. Natural products aren't the solution to our problems. In fact, many natural substances and remedies are complete hogwash without any sort of scientific evidence. There are some exceptions of course, but you get the gist.
Something penetrating the dermis isn't necessarily a bad thing. These sort of products go through clinical testing to ensure their safety. If a new innovation removes or lessens acne scars without severe consequences, then it's something many of us will be excited about. Are scars the worst issue in the world? No. There are many people dealing with much worse things. That doesn't change the reality that human appearance impacts people's perception of you, social outcomes, self esteem, and even quality of life.
I think it's still a good question for a lot of people. I couldn't care less about having synthethic skin instead of "real skin" as long as the material is basically exactly the same and it's not dangerous. I only care about getting back the smooth skin I had before I got stretch marks, like other people do. BUT it is something to take into account for some people. Scars can actually make you feel proud of something sometimes.
One question though: you mentioned people's perception of you depending on your scars. I suppose you mostly mean facial scars rather than body scars right? Because no one will see your skin in the vast majority of your social life (except your sex life), and everyone has scars of some sort on their body.
7 hours ago, Valkyros said:I think it's still a good question for a lot of people. I couldn't care less about having synthethic skin instead of "real skin" as long as the material is basically exactly the same and it's not dangerous. I only care about getting back the smooth skin I had before I got stretch marks, like other people do. BUT it is something to take into account for some people. Scars can actually make you feel proud of something sometimes.
One question though: you mentioned people's perception of you depending on your scars. I suppose you mostly mean facial scars rather than body scars right? Because no one will see your skin in the vast majority of your social life (except your sex life), and everyone has scars of some sort on their body.
Yes, facial acne scars. If someone is proud of their acne scars, I congratulate them. Given the nature of this forum and this thread in particular, most people don't fit into that category
12 hours ago, Lapis lazuli said:Really looking forward to more news from Sunogel.
I really think it's a promising treatment!
Don't want to be the party pooper, but there's been literally no positive sign that sunogel will bring anything to the table: no big investors working with them, no scientists recognized by their peers, no real theory as to how they'r going to procede, 0 news since years, barely any information available.
like, the only thing we know about sunogel is that it''s about pro-regenerative hydrogel, but there are no patents, no viable published results so far, and so on...
Don't count on it too much, most clinical trial companies end up being disappointments.
If you're interested in proper tissue regeneration/scar healing companies, the only really promising companies so far seem to be elastagen (tropoelastin) or direct biologics (exosomes), for all the reasons that were mentioned beforehand.
50 minutes ago, AlexZ77 said:Ye lehran chill put bro, any of these treatments could cause a evolution in skin regeneration, Sunogel might take it a bit longer but its definitely not the next shity SkinTE company
if sunogel wont relase anything new within the next 2 years then we can be sure
I mean, I don't really care who does it as long as it works, it really doesn't matter in general. So if sunogel does it, hell I'll be a happy man as well.
I would like to see some results from elastagen themselves when it comes to stretch marks though, you know, just to be reassured. Sure, the whole concept makes a lot of sense (stimulating elastogenesis and filling the void with synthetic skin in order to restore the skin's overall look and smoothness), but a few pictures would go a long way.
Hey guys, I'm mostly interested in a treatment for stretch marks. I've read everything so far, and If I understood properly, it's either elastagen or direct biologics right? I've found tons of things on elastagen, but nothing about the other one: could anyone give me more details? Thanks.
Elastagen (Tropoelastin) has come from the clouds and making some noise. Any photos? Any estimated timelines?
On 2/29/2020 at 10:57 AM, AlexZ77 said:Guys any news on microcoring on other treatments?
I spoke to the lady who is leading Microcoring in late October 2019. I asked some specific questions about its use for acne scars and how it can properly target only damaged scar tissue for acne scars and so on. She said she couldn't give much away atm because their product is in developmentbut said to stay tuned as they plan ongoing to market this year.
In my personal experience, mechanical devices have given the best improvements so Im really looking forward to seeing what Microcoring can do. And its on the horizon, the same cant be said for anything else discussed here.
18 minutes ago, Skin Pessimist said:Elastagen seems like the most promising option, but who knows how effective it truly is. Even if it works, it will be years before its available and the price might be insane
Very fair point. In fact, the few surgeons/dermatologists who are partnering with them already told me that it would take 2-3 years before the product is out, so you're right about that. They say, based on what they saw, that it works wonderfully well for stretch marks, but I'll believe it when I see it as well.
As for the price, I'm afraid you're going to be right as well: it's going to be very expensive at first (several thousand of dollars prob), and it will only become more accessible later on.
Also, it's not gonna work the same way for everything based on what we found: it apparently works very well for normal stretch marks (0.1-0.6cm large and 5-15 cm long) and atrophic scars, but it's not the solution for hypertrophic scars and big, massive skin lesions.
13 minutes ago, lehran said:Very fair point. In fact, the few surgeons/dermatologists who are partnering with them already told me that it would take 2-3 years before the product is out, so you're right about that. They say, based on what they saw, that it works wonderfully well for stretch marks, but I'll believe it when I see it as well.
As for the price, I'm afraid you're going to be right as well: it's going to be very expensive at first (several thousand of dollars prob), and it will only become more accessible later on.
Also, it's not gonna work the same way for everything based on what we found: it apparently works very well for normal stretch marks (0.1-0.6cm large and 5-15 cm long) and atrophic scars, but it's not the solution for hypertrophic scars and big, massive skin lesions.
My question is how well it works for depressed scars with noticeable loss of volume. The scars that annoy me most are the ones on my cheekbones. My cheekbones are relatively prominent, making the volume loss of the rolling and boxcar scars quite noticeable. I dislike the ice pick scars, but I don't care as much about them. Boxcar and rolling scars can really ruin facial symmetry and volume sometimes.
My main concern is the price. The wait of a few years is annoying, but I'll still be relatively young. If the price is super crazy, I may not be able to afford it for a long, long time.
3 minutes ago, Skin Pessimist said:My question is how well it works for depressed scars with noticeable loss of volume. The scars that annoy me most are the ones on my cheekbones. My cheekbones are relatively prominent, making the volume loss of the rolling and boxcar scars quite noticeable. I dislike the ice pick scars, but I don't care as much about them. Boxcar and rolling scars can really ruin facial symmetry and volume sometimes.
My main concern is the price. The wait of a few years is annoying, but I'll still be relatively young. If the price is super crazy, I may not be able to afford it for a long, long time.
Main concern is the price as well. If you're something like 20-40 years old, it's good, as you'll indeed still be relatively young to enjoy stuff (especially with how drastically longer life will be in the future with biotechnology).
I'm not quite sure about your scars tbh, it really depends how depressed they are.
8 hours ago, AlexZ77 said:The only thing that would get rid of stretch marks is some kind of scarless healing, and we need probably 10 years for that if not more. Microcoring is the nearest possbile treatment rn
When you say "getting rid of stretch marks" you mean 100% I assume? Because if I could reduce their volume by something like 80-90%, it would be good enough for me not to care about them anymore frankly. Ya think elastagen will be able to do that?
13 hours ago, voulzeyes said:When you say "getting rid of stretch marks" you mean 100% I assume? Because if I could reduce their volume by something like 80-90%, it would be good enough for me not to care about them anymore frankly. Ya think elastagen will be able to do that?
Yeah its possible that elastagen will do that but lets be real most people here if not all wont be satisfied until they get 100% improvement