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[Sticky] Scarless Healing

 
MemberMember
10
(@surgical-scar)

Posted : 01/20/2019 1:04 am

15 hours ago, FromScarredtoFree said:

Well when you guysbuild your own company and find a literal holy grail of medicine you can complain about Dr. Sun. I'm sure if he wanted to he could easily become a Beverly Hills dermatologist and charge people 2000 for a Fraxel treatment but he's trying to make improvements to medicine. Lots of people are working very hard to solve issues like scarring but unfortunately the FDAdiscourages innovation and research and makes it difficult and expensive to solve medicalproblems. I'm sure Dr. Sun's product isn't perfect but his pictures of the rat and pig were some of the closest things I've seen to scarless healing.

Yeah we still haven't seen any trials and results from Sunogel to call it bullshit

 

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MemberMember
1
(@jr_shedds)

Posted : 01/23/2019 10:56 am

Someone should start a petition on change.org or facebook's new petition feature for more research on acne and acne scarring. I tried once on here but only got 10 supporters. Need more funding for acne and acne scarring from the NIH, philanthropic foundations, universities, etc. Real research not just combining old creams to make new ones which is mostly done right now.

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(@binga)
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(@khakiskewer)
MemberMember
40
(@anish004)

Posted : 02/01/2019 9:20 pm

4 hours ago, KhakiSkewer said:

all these researches should retire ..

tired of such articles ,fast wound healing was seen

complete regenration occured

 

all these are nonsense ....nothing gonna come

seen these type of news and articles from many years,nothing came

only option is to correct our scar is study become researches,research,find smthng that works,use it on ur own skin(no need of FDA for this)

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MemberMember
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(@genetrouble)

Posted : 02/02/2019 8:23 am

10 hours ago, Anish004 said:

all these researches should retire ..

tired of such articles ,fast wound healing was seen 

complete regenration occured

 

all these are nonsense ....nothing gonna come

seen these type of news and articles from many years,nothing came

only option is to correct our scar is study become researches,research,find smthng that works,use it on ur own skin(no need of FDA for this)

1. It's not a science paper, it's just a journalist article that always exaggerates things. 

2. Good luck with studying and becoming a researcher, our "only option" :) And finding on your own that "smth" ofc. Just do it! 

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MemberMember
40
(@anish004)

Posted : 02/02/2019 10:11 pm

13 hours ago, GeneTrouble said:

1. It's not a science paper, it's just a journalist article that always exaggerates things. 

2. Good luck with studying and becoming a researcher, our "only option" :) And finding on your own that "smth" ofc. Just do it! 

thanx for trolling me and best of luck for ur scar solution by these statements "scarless healing was seen in mice etc and also fs2

good luck

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MemberMember
60
(@mybeautifulscars)

Posted : 02/09/2019 11:13 pm

https://www.eurekalert.org/pub_releases/2019-02/uoc--usr020719.php

Exciting news from Cotsarelis' team. Seems the research is advancing.

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MemberMember
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(@lip121212)

Posted : 02/10/2019 4:15 pm

Does Cotsarelis' team know about Sunogel's work?

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(@rez77)

Posted : 02/12/2019 2:56 am

Its kind of sad there's been such little enthusiasm as of late on this thread.

 

Fuck I remember when this thread started 12 years ago and some people had some hope. Can't have much hope now that we got old.

 

Still there's stuff like this. Why isn't anyone talking about this:

 

https://science.howstuffworks.com/innovation/everyday-innovations/lab-grown-skin2.htm

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MemberMember
60
(@mybeautifulscars)

Posted : 02/12/2019 5:48 pm

Welcome back Rez.

Unfortunately, nobody cares enough about scars to do something about it. Most of us accept them and go on. Scientists have other priorities to tackle including finding functional cures to cancer, HIV and MS. I do believe we have the cures but it's all politics.

You have some research going on if you have followed the thread the last few months including but not limited to papers published by a team headed by Cotsarelis at UCI.It can take years however before any treatment comes out of this if anything really does. Cotsarelis has been promising a permanent solution to male alopecia and we are still light years away, I'm blessed at least with hair but acne really disfigured me.

You have few startups testing anti scarring drugs including FS2 and OLX101. They are in phase 2 of clinical trials so we are hoping they don't fail. People were once raving about Sunogel and Polarity but the enthusiasm has faded for these two. Dr. Sun doesn't seem to be moving forward with his hydrogel and Polarity is moving ahead by presenting itself as an alternative to skin grafts.

One day, scars will be historybut we will never probably see it in our lifetime. Make the best of what you have presently.

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(@binga)
MemberMember
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(@binga)

Posted : 02/14/2019 6:29 am

looks like scarless healing to me

 

https://www.linkedin.com/pulse/next-phase-treating-skin-laxity-coming-2019-marc-weiser/

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MemberMember
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(@anish004)

Posted : 02/14/2019 8:50 am

2 hours ago, Binga said:

1.5mm diameter?? than how the hell it can heal scarlessly.

i am a supporter of microcoring but 1.5mm diameter is big for healing scarlessly

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MemberMember
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(@nikki_gargin)

Posted : 02/14/2019 8:57 pm

Its not scarless healing its healing by contraction which is scarless under 2mm of injury. In theory might improve acne scarring? A bit like laser would though.

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(@beanbagdog)

Posted : 02/15/2019 10:30 am

On 2/12/2019 at 5:48 PM, MyBeautifulScars said:

Welcome back Rez.

Unfortunately, nobody cares enough about scars to do something about it. Most of us accept them and go on. Scientists have other priorities to tackle including finding functional cures to cancer, HIV and MS. I do believe we have the cures but it's all politics.

You have some research going on if you have followed the thread the last few months including but not limited to papers published by a team headed by Cotsarelis at UCI.It can take years however before any treatment comes out of this if anything really does. Cotsarelis has been promising a permanent solution to male alopecia and we are still light years away, I'm blessed at least with hair but acne really disfigured me.

You have few startups testing anti scarring drugs including FS2 and OLX101. They are in phase 2 of clinical trials so we are hoping they don't fail. People were once raving about Sunogel and Polarity but the enthusiasm has faded for these two. Dr. Sun doesn't seem to be moving forward with his hydrogel and Polarity is moving ahead by presenting itself as an alternative to skin grafts.

One day, scars will be historybut we will never probably see it in our lifetime. Make the best of what you have presently.

I dont think that much pessimism is necessary, itll probably another decade or two but Im sure well see something that will be good enough in our lifetime. I feel you have to take into account other areas of research when talking about any research at all because they all have the potential to speed up, or even acidentally find the solution to another problem.

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(@ai3forever)

Posted : 02/17/2019 8:03 am

https://gizmodo.com/complete-axolotl-genome-may-be-a-huge-step-toward-human-1832015926

 

Another step in the right direction. If only all the worlds top scarless healing researchers work together, we probably have a cure by now.

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60
(@mybeautifulscars)

Posted : 02/17/2019 3:18 pm

On 2/15/2019 at 10:30 AM, Beanbagdog said:

I dont think that much pessimism is necessary, itll probably another decade or two but Im sure well see something that will be good enough in our lifetime. I feel you have to take into account other areas of research when talking about any research at all because they all have the potential to speed up, or even acidentally find the solution to another problem.

I really hopesomething comes out in a decade or two but I'll be in my 50s by then. Who cares about scars then.

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(@binga)

Posted : 02/18/2019 7:45 pm

http://mesoestetic.ro/images/prxt/prxt33.pdf

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(@binga)
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(@nikki_gargin)

Posted : 02/18/2019 11:55 pm

Good its coming out of China this hydrogel... more likely to get funding and approval! Two year wait?

 

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(@surgical-scar)

Posted : 02/23/2019 4:40 pm

Assuming microcoring does contract the skin without scar... what about the fat that is removed with it and won't get regenerated? It will be like a facelift without fat graft that ages your look. A youthful face is plump with fat.

As we will age by the time we do this procedure, we have already lost some fat in the face due to aging. I already plan to do fat transfer to the face for the most plump youthful appearance.

Fat loss in the face isn't pretty even if it's scar free.

It may not matter if you do one or few punches, but so many punches all over the face that will remove the fat irreversibly?

 

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(@Anonymous)

Posted : 02/23/2019 4:51 pm

Microcoring has already had a full clinical trial in humans for wrinkles and was found to heal scar free and remove up to 5-7% of the total facial skin without scars.  The size of the needle is incomparable to an excision biopsy, as it it 22 gauge.  For reference a botox needle is often 30 gauge and a filler needle is 27 gauge.  Currently it is in trials for acne scars which will end January of next year however they found in wrinkles it is completely safe and heals with no scarring.  This is because small full thickness wounds the body chooses to heal with regeneration as opposed to scarring.  Here is a picture from the wrinkle clinical trial for reference.  

"From the Boston-based biotech company Cytrellis comes the world™s first dermal micro-coring device, an energy-free needling tool that mechanically drills out minuscule columns of skin”each less than half a millimeter in diameter”in a fractional pattern across the mid and lower face, scarlessly removing 5 to 7.5 percent of the total surface area to shrink the skin overall, explains New York City dermatologist Robert Anolik, MD, a researcher on the trials. œWe're using 22 gauge needles to core out the skin, so these excises are tiny," he says. (For reference, a Botox needle is typically 30 or 32 gauge, and a filler needle 27 or 30 gauge, with higher numbers indicating smaller needles.) "The gaps left behind then come together and heal up, triggering the remodeling phase of collagen for a firming effect, Dr. Anolik adds."22Gauge.thumb.png.0b66a82a0c477f3489178e082e397d4f.png49902-jolenepng.png.708cd2eeefa5fd42d8b38344bc33933b.png

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MemberMember
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(@surgical-scar)

Posted : 02/23/2019 4:57 pm

12 minutes ago, surgical scar said:

Assuming microcoring does contract the skin without scar... what about the fat that is removed with it and won't get regenerated? It will be like a facelift without fat graft that ages your look. A youthful face is plump with fat.

As we will age by the time we do this procedure, we have already lost some fat in the face due to aging. I already plan to do fat transfer to the face for the most plump youthful appearance.

Fat loss in the face isn't pretty even if it's scar free.

It may not matter if you do one or few punches, but so many punches all over the face that will remove the fat irreversibly?

 

Also,

Wrinkles are surrounded by healthy skin...

A tiny punch inside a scarred area is not surrounded by normal skin...

Where are the pictures for punches healing inside of a scarred area? Do you expect to get dots of normal leveled skin inside of scar patches?

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0
(@Anonymous)

Posted : 02/23/2019 5:15 pm

6 minutes ago, surgical scar said:

Also,

Wrinkles are surrounded by healthy skin...

A tiny punch inside a scarred area is not surrounded by normal skin...

Where are the pictures for punches healing inside of a scarred area? Do you expect to get dots of normal leveled skin inside of scar patches?

It is still in clinical trials and we will find out more in January. I have had actual excisions (with good results) before and they do not touch the fat layer. In general it is very difficult to remove or damage the fat layer physically because it is much harder than the skin. That is why most damage to the fat layer comes from thermal damage in lasers. Aging causes fat cells to die which is why we appear older usually. This company is essentially trying to create a more accurate fraxel that does not cause thermal damage. In theory this procedure can be repeated several times to remove all traces of scarring. Acne scar wound healingis different because it is also a bacterial infection in addition to a wound.If a 22 gauge wound is considered by the body inconsequential, there is a good chance it will heal with regeneration as opposed to scarring, regardless of the surrounding skin. The microcoringcompany recognizes that lasers are poor choice (I believe they called it false advertising) and they are trying to make an improvement.

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