Acne.org Products
14 hours ago, FromScarredtoFree said:Yeah it's definitely getting more attention now. Britain recently opened a wound healing hub and plans to cure scarring within a generation. The also stopped funding movies that portray villains with scars because it feeds into the stereotype that scars=bad. I don't think scarless healing will be in the US first. I think it will be in a country with universal healthcare first. I've also heard that China has made a lot of discoveries in scarless healing and regenerative medicine.If you search scar free healing on google scholar for example there are at least 30 well conducted studies that reduced or eliminated scarring in rats/pigs just this month. And those are just articles in English. The people making these discoveries aren't millionaires, they're mostly grad students/professors. But the FDA expects them to cough of millions of dollars just to test their discoveries in humans. This is why we end up with scamcompanies like Skinte that know how to manage the business side well and get approvedbut have dubious science. I get that the FDA has to protect people but if someone wants to take a risk with their life or scars or whatever that should be their right. But to me it seems that a lot of Doctors and the FDA hide behind "ethics" for unethical reasons.
OLX10 is under human trials at the moment in the UK. Phase 1 currently. So looks like there about a year or so behind birchbiomed. I think your right they have the science its a matter of money and legislation to start seriously rolling it out.
Oh and on NHS in UK it would depend. Nothing deemed 'cosmetic' is on the NHS. They wont give an adult over 18 braces even with the worst teeth in the world. I had to wait 2 years for a panel to approve. I see the private sector being more successful. Korea would be on it quickly!
1 hour ago, nikki_gargin said:OLX10 is under human trials at the moment in the UK. Phase 1 currently. So looks like there about a year or so behind birchbiomed. I think your right they have the science its a matter of money and legislation to start seriously rolling it out.
Oh and on NHS in UK it would depend. Nothing deemed 'cosmetic' is on the NHS. They wont give an adult over 18 braces even with the worst teeth in the world. I had to wait 2 years for a panel to approve. I see the private sector being more successful. Korea would be on it quickly!
How does approval work in Korea or the UK? How soon is OLX101 going to be on the market if it does work? How many trials do they have to go through in each company?
On 10/31/2018 at 1:20 AM, golfpanther said:Great finds everyone!
It's important to note that all of these involve manipulation of cells and/or pathways so they'd face a strenuous process for approval and testing.
Nevertheless, good news for us that so many researchers are actively trying so many different ways to figure this out.
Can you give me some sunogel ? Thank you.
19 minutes ago, momo11111 said:OLX101 and FS2 are both for hypertrohpic scars.... so I don't think it will work on atrophic scars
It will work in the scar tissue of the atrophic scar.
news update. Birchbiomed say could have fs2 topical on market earliest within a year. Also it won™t need a prescription
8 hours ago, Anish004 said:just want to know if FS2 and OLX 101 can prevent scarring in fresh wounds ?
than theoretically we can remove any scars
Fs2 claim yes, Anish 
lip 121212 if you type birchbiomed in google there is a 5 min vid with the CEO dated 5th december where he says.
On 12/12/2018 at 11:30 AM, slave of jesus said:Can you give me some sunogel ? Thank you.
Haha, I wish I could!
In terms of news on Sunogel, Dr. Sun just made a big presentation (not sure where). It's posted on his Facebook page.
i guess every person here have scarsmaybe severe or not but spreaded on diff parts of face .. and not isolated at one place so how can a scarless healing product for wounds will help us
i am positive about scarless healing thing as it will help prevent scarring but today while i was looking my face closely aside of big scars i have many many tiny small scars which dont look up in normal lighting. and its not possible to cut our face and apply it all over
yes we can do it for larger scars but for small scars all over face a scarless healing thing with lasers or anything else will be better and for larger ones excision and scarless healing product may work better
3 minutes ago, Anish004 said:i guess every person here have scarsmaybe severe or not but spreaded on diff parts of face .. and not isolated at one place so how can a scarless healing product for wounds will help us
i am positive about scarless healing thing as it will help prevent scarring but today while i was looking my face closely aside of big scars i have many many tiny small scars which dont look up in normal lighting. and its not possible to cut our face and apply it all over
yes we can do it for larger scars but for small scars all over face a scarless healing thing with lasers or anything else will be better and for larger ones excision and scarless healing product may work better
These tiny holes are your pores. Stop stressing too much. Some people have large pores and oily skin which makes them prone to acne. Large pores are not scars. You can get laser treatments, they can tighten up the pores and shrink them.
1 hour ago, MyBeautifulScars said:These tiny holes are your pores. Stop stressing too much. Some people have large pores and oily skin which makes them prone to acne. Large pores are not scars. You can get laser treatments, they can tighten up the pores and shrink them.
they are not pores i have large pored all over my face bt many of them stretched and widened up like scars ...
and yes i have oily skin and extra large pores but that dont bother me
49 minutes ago, Anish004 said:they are not pores i have large pored all over my face bt many of them stretched and widened up like scars ...
and yes i have oily skin and extra large pores but that dont bother me
Drugs like fs2 work on a molecular level Anish. In tablet form it will break down all scar tissue even internal scarring so stop stressing. Like accuntane doesnt discriminate from your face or your back nor does fs2 tablet. But you will need to wait maybe 4 or 5 years for that.
anyways topical fs2 you dont need to cut anything open.
FS2contains a molecule known as kyrunenine. It acts on fibroblasts to stop over collagen production. Researchers have high hopes that this can become a new anti-scarring treatment.
When human skin is injured, fibroblasts rush to the injury and start laying down new collagen, this is known as fibrosis and the same process occurs in other human organs. The new tissue or collagen is called granulation tissue which fills almost every wound.
New collagen is layed down fast, overexpressed and does not mimic what was there before. Skin follicles, fat cells, pores and melanin producing cells are seldom repaired. Normal collagen however is aligned in random directions or in a criss-cross manner. We call this thebasket weave pattern.
Overexpression of collagen creates two types of scars: hypertrophic or keloids. This is considered abnormal healing. Deep wounds will always form a hypertrophic scar which over time becomes a fine line scar for most individuals. Movement greatly influencesthe thickness of the scar. if the injuryis located close to a joint, scarring will be more prominent due to tension.
Many are not so lucky and their bodies will not try to flatten hypertrophic scars over time. Keloids tend to go beyond the original injury creating thick hard lumps of collagen on different parts of the body over time. They are considered benign tumours because fibroblasts go out of control.
In burns, you get contracture scars. In humans, wounds heal by contraction. Fibrosis creates yet again huge lumps of collagen which are stretched due to movement. Contracture scars limit movement especially if they cover large areas over joints. They also lack pores which help regulate body temperature in extreme heat.
Stretchmarks are also scars created once more by tears inside the dermis due to tension, the end result are strecthed wrinkly lines on the surface of the skin.
Small cuts, donot have too much fibroblasts, so collagen isre-aligned in a basket weave pattern. The fibroblasts die off, become fat cells or adipocyte cells. This is due to the fact that hair follicles are not damaged and secrete BMPs which turn fibroblasts into fat cells.The skin regenerates and looks similar as before.
In bigger wounds, fibroblasts linger behind overproducingcollagen, the scars remain. Fibroblasts eventually die off but the skin lacks hair follicles so they are no BMPs to signal the fibroblasts to realign all this collagen into normal healthy skin again.
Researchers however at UCI found a way to reprogram fibroblasts into fat cells. The secret is to regenerate hair follicles into open wounds first. They obviously will not tell us how they managed to do that. The new regenerated hair follicles will secrete BMPs again and scarless healing is achieved.
Therefore, I do not believe FS2 can do anything about atrophic scars which lack collagen. Sometimes fibroblasts do not produce enough collagen and the scar results in a sunken appearance or what we call an atrophic scar. Acne and chicken pox tend to leave behind these type of facial scars. Most of us have these type of scars anyways. FS2 will not help us. I also do not believe it does anything about missing hair follicles and pores.
Recell got approved in the US few months back. Looks like a game changer for burn victims.
5 hours ago, MyBeautifulScars said:FS2contains a molecule known as kyrunenine. It acts on fibroblasts to stop over collagen production. Researchers have high hopes that this can become a new anti-scarring treatment.
When human skin is injured, fibroblasts rush to the injury and start laying down new collagen, this is known as fibrosis and the same process occurs in other human organs. The new tissue or collagen is called granulation tissue which fills almost every wound.
New collagen is layed down fast, overexpressed and does not mimic what was there before. Skin follicles, fat cells, pores and melanin producing cells are seldom repaired. Normal collagen however is aligned in random directions or in a criss-cross manner. We call this thebasket weave pattern.
Overexpression of collagen creates two types of scars: hypertrophic or keloids. This is considered abnormal healing. Deep wounds will always form a hypertrophic scar which over time becomes a fine line scar for most individuals. Movement greatly influencesthe thickness of the scar. if the injuryis located close to a joint, scarring will be more prominent due to tension.
Many are not so lucky and their bodies will not try to flatten hypertrophic scars over time. Keloids tend to go beyond the original injury creating thick hard lumps of collagen on different parts of the body over time. They are considered benign tumours because fibroblasts go out of control.
In burns, you get contracture scars. In humans, wounds heal by contraction. Fibrosis creates yet again huge lumps of collagen which are stretched due to movement. Contracture scars limit movement especially if they cover large areas over joints. They also lack pores which help regulate body temperature in extreme heat.
Stretchmarks are also scars created once more by tears inside the dermis due to tension, the end result are strecthed wrinkly lines on the surface of the skin.
Small cuts, donot have too much fibroblasts, so collagen isre-aligned in a basket weave pattern. The fibroblasts die off, become fat cells or adipocyte cells. This is due to the fact that hair follicles are not damaged and secrete BMPs which turn fibroblasts into fat cells.The skin regenerates and looks similar as before.
In bigger wounds, fibroblasts linger behind overproducingcollagen, the scars remain. Fibroblasts eventually die off but the skin lacks hair follicles so they are no BMPs to signal the fibroblasts to realign all this collagen into normal healthy skin again.
Researchers however at UCI found a way to reprogram fibroblasts into fat cells. The secret is to regenerate hair follicles into open wounds first. They obviously will not tell us how they managed to do that. The new regenerated hair follicles will secrete BMPs again and scarless healing is achieved.
Therefore, I do not believe FS2 can do anything about atrophic scars which lack collagen. Sometimes fibroblasts do not produce enough collagen and the scar results in a sunken appearance or what we call an atrophic scar. Acne and chicken pox tend to leave behind these type of facial scars. Most of us have these type of scars anyways. FS2 will not help us. I also do not believe it does anything about missing hair follicles and pores.
No there is no mention of hair follicles and pores your right. I dont think FS2 is 100% perfect skin. Never did. But maybe normal looking scars eg even you cant really tell its there.
3 hours ago, nikki_gargin said:No there is no mention of hair follicles and pores your right. I dont think FS2 is 100% perfect skin. Never did. But maybe normal looking scars eg even you cant really tell its there.
I have a lot of scars all over my shoulders, upper arms, back,face and other areasthat would love to get rid of one day.They are all caused by stupid stubborn acne that wouldn't go away.
I still battle minor breakouts even 20 years later.Now, I am plagued by another ailment,folliculitis, which probably is a consequence of all those acne fighting products I used over the years. For most of my life, my skin is irritated, inflamed with cysts and blackheads covering even my legs. Nothing ever worked apart of Accutane which I finally took a try last year. For the first time, my skin is clear and healed up.
The way things are going, I believe a solution won't happen before another decade or more. My hopes are that FS2 can diminish or at leastfade most of my body scars. If they can enter the market by 2019, then I can at least buy the product over the counter and start usingit. Having clear skin scar free is quite liberating. The scars are white and raised with some pitts on my face.
Recell, TCA andskin resurfacing all seemed revolutionary ata time. They are costly and improvements are very minimal however. Inever did go for any of these treatmentsas I learned to accept my scars and moved on.
Let's just hope that Fzs2 is not another failure.
On 12/17/2018 at 2:06 PM, golfpanther said:Post from December 13th. First thing that pops up on his feed if you go to his page.
I checked and the last post is from March, at least on sunogels page and they didnt have anything. Dr sun did say that they might be pairing up with a dermatology company to get it on the market faster
17 hours ago, Lip121212 said:I checked and the last post is from March, at least on sunogels page and they didnt have anything. Dr sun did say that they might be pairing up with a dermatology company to get it on the market faster
Oh, not Sunogel's, but Dr. Sun'spersonal page has a pic and a writeup of what they hope to achieve.
I was the one talking to Dr. Sun when he stated they might work with a derma company to create funding by bringing cosmetic products to the market. That was a bit ago so I'm not sure where that stands now.
2 hours ago, Lip121212 said:I know its not my place, but there has to be something we can do to speed up the process of sunogel. Dr. sun even stated that funding was the number one reason why it hasnt been moving as fast. Is there a go fund me page we could do? I know its a long shot but.
Dr. Sun's major obstacle is finding a reputable pharmaceutical company willing to work with him as a partner. Without this, his product is toast. No company would ever invest without any concrete results until he proves that his product truly works. So let's not start throwing money away on something that we don't even know about.
BirchBiomed started at UBC and they are already testing their product, FS2 on people. They have funding from the university,are approved by both Health Canada and the FDA to conduct trials.
I believe Dr. Sun should have stayed at Gemstone. They had funding from John Hopkins. For this reason, I believe its time to throw the towel on Sunogel. BirchBiomedwill probably launch a product before Sunogel ever does.
Sunogel will however conduct trials as of 2019 according to their website so they might have found a company willing to work with Dr. Sun. Yet again, we only have a pic of a small finger cut that healed nicelyafter applying Sunogel. Small cuts heal with barely any scarringanyways. Dr. Sun never showed us any results for bigger wounds.
I have high hopes for FS2. We also have UCI researchers who have found a way to convert fibroblasts into fat cells to achieve scarless healing. We also have Olx101. Scientists are working hard to find something for scars.
However, weneed to wait probably another few years until a product comes out that truly addresses scarring. Giving away money to Dr. Sun for a unproven anti-scarring treatment will not speed up things.