Acne.org Products
On 11/20/2018 at 3:33 AM, Lip121212 said:Hi Everyone,
I just wanted to post an update. I have been in contact with Guoming Sun of Sunogel via LinkedIn and said that they are the process of moving the product into clinical trials in 3Q 2019 which some of you I presume already know. He said that it is being classified as a medical device and will be testing it as a medical advice (there was some talk on here before that he wanted to do clinical trials like it would be a drug). After this I asked him a general timeline of when he could for see this being out (if successful) and he said on average when in clinical it takes about 3 years for FDA approval. We are looking at 2021-2022 if it works...
This is brilliant news. Fs2 topical applicationif successful should be released before sunogel so its giving us options atleast!
On 11/23/2018 at 2:29 PM, nikki_gargin said:This is brilliant news. Fs2 topical applicationif successful should be released before sunogel so its giving us options atleast!
I can't wait to see what FS2 can do for scars. I've got multiple hypertrophic scars from a past car accident that I would like to fade.
3 hours ago, Anish004 said:even after success
FS2 will take more time because its a drug
They are planning to release it next year. They are in phase 2 clinical trials right now. Phase 3,the drug is prescribed to more people. If it passes phase 2, your physician might prescribe you the drug at phase 3 and monitor you.
10 hours ago, MyBeautifulScars said:They are planning to release it next year. They are in phase 2 clinical trials right now. Phase 3,the drug is prescribed to more people. If it passes phase 2, your physician might prescribe you the drug at phase 3 and monitor you.
phase 3 is a trial ..can a person use it at that time
trial means trial done to check its efficiancy side effects etc.
They are planning on releasing the topical fs2 cream soon. Its the oral that they need to wait 2 years to complete phase 2 trial. There plan is to make revenue from the cream to fund there other products. The cream showed no side effects in healthy volunteers. They are now testing efficacy of the cream. Phase 3 can be a wider patient group so what Mybeautifulscars said is right.
There are 2 trials yeh?
The topical cream being run in Florida and the therapeutic treatment on post surgical wounds/scars in Canada which is the phase 2 and the one we have more interest in.
there Was a video interview with them and they said the cream would come out if successful next year. I dont know if its 100% regeneration, but it breaks down scar tissue which could mean the body begins to regenerate or more normal skin looking scars form. I guess it could also be a mixture of the two tissues which is a million times better than what we have now! We dont 100% know but the medical field is excited atleast. More excited than polarity!
WhatFS2 does is break down existing raised scars. It won't work on atrophic scars most likely. Most of us have this type from past acne battlesanyways.
Atrophic scars are the name given to those deep skin depressions that develop after pimples heal. These scars can be classified further into rolling, box or ice pick scars. They result from fat or collagen loss not collagen buildup.
It's seems to bereally targeted right now towardshypertrophic or keloid scarswhich happendue to collagen buildup. Apparently, it's composed of a molecule that breaks down the proteinresulting in a smoother skin complexionI would assume.It would likely be the same for contracture scars. Burn survivors can really benefit from it.
Once completed, phase 2 trials will indicate if thisimprovement is anywhere between 10 or100%.I don't believe its 100% skin regeneration. Its most likely a substitute to existing steroid injections, lasers or silicone sheets which flatten raisedscars. It may also give better results than the existing methods. We don't really know right now. I believe it promotes collagen realignment of scar tissue into the basket wave pattern that composes healthy skin.
The good thing to note however about this experimental drug is that supposedly it prevents scarring in new wounds. So surgeons can theoretically excise scarred skin, apply FS2 on it and no new scar will form thusthe old scar vanishes completely, a bit like Polarity minus the skin biopsy.
20 hours ago, Lip121212 said:I have hypertrophic scars on the inside of my lips and so it for sure will do prevent scarring if I have my scars excised? Does anyone have the video saying it will be out next year?
I don't think you need to worry about scars inside your mouth. Nobody sees them.
8 hours ago, Lip121212 said:Sorry to post two times in a row, but I dont get how they will get FS2 on the market soon. They are only in phase 2 and they still need to do phase 3 and a review process. They have a phase 4 where they motinor the drug on the market after approval
We will see. It's too early to tell.
There is a interview on YouTube Where they say next year for topical. I think they are being funded to push through as quick as they can to be honest because they potentially have the ability to save millions of dollars. The oral drug trial on patients will really show us how it works because they are using it on new burn wounds. We have all seen polarity so we can really compare.
also if it can get basket weave then you can assume it will make scars invisible under makeup. The main problem in scars is the lack of basket weave.
12 hours ago, nikki_gargin said:There is a interview on YouTube Where they say next year for topical. I think they are being funded to push through as quick as they can to be honest because they potentially have the ability to save millions of dollars. The oral drug trial on patients will really show us how it works because they are using it on new burn wounds. We have all seen polarity so we can really compare.
also if it can get basket weave then you can assume it will make scars invisible under makeup. The main problem in scars is the lack of basket weave.
why scar differ from skin in texture ? is it due to lack of basketweave pattern ?
i am not talking about its height depth color or appendages but the textue in which a scar differs from skin and lack
also the skin has criss cross lining if u look closely and its totally lacking in scar tissue.
is it all due to basket weave pattern lack?
1 hour ago, Lip121212 said:Hey, so I emailed with FS2's marketing department and the lady said it would elimate "all scarring" in new scars. Does this mean all sorts of types of scars or it would remove all scarring and only new healthy skin would regenerate. It just seems FS2 is really tricky with their wording on their website and in the video on youtube.
When they will release it ask this also to them
4 hours ago, Lip121212 said:Hey, so I emailed with FS2's marketing department and the lady said it would elimate "all scarring" in new scars. Does this mean all sorts of types of scars or it would remove all scarring and only new healthy skin would regenerate. It just seems FS2 is really tricky with their wording on their website and in the video on youtube.
Like I mentioned above, they claim it eliminates scarring in fresh wounds. If you have an existing scar, it doesn't eliminate it but it reduces its appearance.
On 12/2/2018 at 7:20 PM, Lip121212 said:Awesome! Does anyone know of any published articles that display this in human like skin models or on pigs etc? Ive checked on Birch Bios website in published media, but there are about 15 articles and from the ones Ive seen only one claims 80 percent regeneration in a rabbit ear
Unfortunately, this is the only information right now available online. There is a picture of a rabbit ear with a raised scar that is slowly becoming levelled with the rest of the skin.
On 12/1/2018 at 12:06 PM, Anish004 said:why scar differ from skin in texture ? is it due to lack of basketweave pattern ?
i am not talking about its height depth color or appendages but the textue in which a scar differs from skin and lack
also the skin has criss cross lining if u look closely and its totally lacking in scar tissue.
is it all due to basket weave pattern lack?
Yes basket weave is to do with it. Its also why scars are only 80% strong as normal skin because scar tissue goes in one direction making a load harder on the skin to stretch. Basket weave has strengh in all directions.
They are starting phase 3 of trials 4Q 2019 for topical fs2 but!!with medical devices Phase 3 runs into market like polarityte done 6 months of phase 3? And now you can source it for personal use. Phase 4 is market entry but kept an eye on so they run 3 into 4 with these things. Summer 2020 we will have it.
he is the link. If you click the click here link in the article you fill out a form and can see slides etc x
http://birchbiomed.ca/wp-content/uploads/2018/11/112818-Birch-presents-LD-Micro-FINAL.pdf
can anyone tell me how fs2 work on scar
by reducing its size or making scar bettter in appearancebut in same size(as all topicals and sheets in market do)
if u think practically reducing size would be better because it means repeating applications in time make scar vanish completely by reducing it size repeatedly
but in same size appearace improvement is waste of wait for it
6 hours ago, Anish004 said:can anyone tell me how fs2 work on scar
by reducing its size or making scar bettter in appearancebut in same size(as all topicals and sheets in market do)
if u think practically reducing size would be better because it means repeating applications in time make scar vanish completely by reducing it size repeatedly
but in same size appearace improvement is waste of wait for it
You need to read the science Anish. All you have to do is go to their website. And no doesnt reduce size as in diametre.
21 hours ago, nikki_gargin said:They are starting phase 3 of trials 4Q 2019 for topical fs2 but!!with medical devices Phase 3 runs into market like polarityte done 6 months of phase 3? And now you can source it for personal use. Phase 4 is market entry but kept an eye on so they run 3 into 4 with these things. Summer 2020 we will have it.
he is the link. If you click the click here link in the article you fill out a form and can see slides etc x
http://birchbiomed.ca/wp-content/uploads/2018/11/112818-Birch-presents-LD-Micro-FINAL.pdf
If you don't mind, can you please upload some of those slides? It redirects me to register when I click on here. Unfortunately, I cannot register because I don't have a username and password, it won't allow me to create a profile to register.
We get it you demand a magic potion that without excision vanishes existing scars to the absolute zero...now go invent some and stop filling these pages
12 hours ago, Lip121212 said:Wait it doesnt make it shrink in diameter? Yall Im so confused Im sorry! But if it prevents all scarring in fresh scars then doesnt it just grow normal new skin?
Reduces the visibility and the density of scar tissue of course. Nothing shrinks diameter.
On 12/6/2018 at 11:40 PM, Lip121212 said:Wait it doesnt make it shrink in diameter? Yall Im so confused Im sorry! But if it prevents all scarring in fresh scars then doesnt it just grow normal new skin?
The only way a scar shinks smaller is through contraction which is a bad thing and the body has to do it on its own. Fs2 topicallike surgicalscar said it will get old scars to breakdown and remodel and improve them..maybe partial regeneration..we dont know yet,but in fresh woulds they claim scarless healing