Acne.org Products
Minimal scarring would be awesome for people like me with disfiguring scars on the back.
I hope it's true
btw it looks like investors are starting to believe in SkinTE.....the company is up 11% today and the stock price is now 30$
On 6/18/2018 at 10:58 PM, agelessfrost said:I really think it depends on the level of skin excision. Micrografting has shown amazing results.
Example: [removed]
You can still see the margin but for horrible body scars, this could be great I believe.
does look really good but his arms are hairy! So blends it all in nicely but the hair grows through the micrograft which is a good sign.
Im hoping to have a round two of tissue expansion to move my scar into a more coverable place next April. I have skinte is available for me in 3 or 4 years time to end this horrible nightmare ive been in.
36 minutes ago, Delto said:Does anyone know of a place to get updates on scarless healing that is more focused on the topic?
The amount of people in this thread that try to derail the topic with their sob stories is annoying and unproductive.
36 minutes ago, Delto said:Does anyone know of a place to get updates on scarless healing that is more focused on the topic?
The amount of people in this thread that try to derail the topic with their sob stories is annoying and unproductive.
There's not much to report.
We have many startups who claim to have achieved scarless healing. Information and peer reviewed articles are very limited.
1) SkinTE seems to be forerunner right now. They have the funds. They are using their product on individuals with ulcerations and burns. Patients seem to be healing quite nicely from limited info shown on their website and press conferences. Pics shown do not seem to indicate 100% scarless healing as they claim however. Data is very limited at this point. Results are impressive six months in of using SkinTE on fresh wounds. They claim to be working on a derivative to help individuals with smaller scars so the procedure won't be as invasive.
2) Sunogel claims to achieve scarless healing as well but they have nothing to show at this stage. They seem to be lacking the funds to continue with their product.
3) FS2 from BirchBiomed is at phase 2 of clinical trials. It can take anywhere from 2 to 10 years before all clinical trials are finished. The drug can fail at any stage. Important to note, they claim the drug breaks down existing scar tissue so it does not give us 100% scarless healing.
4) A team headed by Dr. Cotsarelis found a way to eliminate scarring on fresh wounds. They published a paper in Jan. 2017 but there's no updates ever since.
5) There is another french start up who seems to be using 3D bioprinting to possibly excise existing scars and replace them with skin created in a lab. This would be skin grafting so once again not scarless healing. Many companies are already using this technology as we speak. Pharrell Williams tried to cover his tattoos using this technology.
6) Stratamark seems to have developed a product that eliminates stretchmarks but Internet reviews are poor about the product.
7) Many plastic surgeons are finding to new techniques to make scars less visible. Once again not scarless. There are more startups out there but they are so many, it is hard to enumerate them all. There's was a company using tropoelastin or elastagen to achieve scarless healing. They were bought out by the makers of Botox but there's not much to report.
8) Scientiests have also developed a skin gun using stem cells from Renova. Once again, we do not know if this is 100% scarless healing.
9) There is also a new skin glue developed by scientists which closes wounds within seconds. We don't know if this scarless. It uses tropoelsstin.
10) There are 2 drugs that reduce scar formation significantly. I forget the names. These drugs come with a wide range of life threatening side effects and are not prescribed at all. They are used to treat other diseases instead.
This is where we currently sit. In a few years, someone will crack it.
MyBeautifulscars no.9 is totally wrong the Glue created to close wound was made from Decorin (already proved to provide scarless healing..but its hard to synthesise) not tropoelastin
and
no 10 ..those two drugs which reduces scar formation to much extent are
Topiramate and Pirfenidone (also known as kitoscell) come with some side effects which is topiramate pirfenidone doesnt have side effects
i thought sunogel may be our saviour but he is so slow..maybe our childrens when they will be in their 20s thankful to sunogel
3 hours ago, Anish004 said:MyBeautifulscars no.9 is totally wrong the Glue created to close wound was made from Decorin (already proved to provide scarless healing..but its hard to synthesise) not tropoelastin
and
no 10 ..those two drugs which reduces scar formation to much extent are
Topiramate and Pirfenidone (also known as kitoscell) come with some side effects which is topiramate pirfenidone doesnt have side effectsi thought sunogel may be our saviour but he is so slow..maybe our childrens when they will be in their 20s thankful to sunogel
I wonder where I can get Pirfenidone.
16 hours ago, Anish004 said:some sort of scarrig will still occur with skinTe
Here is what I have to say skinTE is a product of a incredible platform of polarityTE with the use of lgr6 stem cells which can regeneration every tissue of the human body that's the key word minimal scarring may happen because that's how the human body heals naturally after a wound but skinTE has shown regeneration of human body the scarring may happen sometimes because of the aggressive procedure and the big wound which skinTE covers don't forget that Swanson said that some derivatives will treat fine line scars and acne scars without the need of aggressive procedure and The create of the wound bed this tell me that without the creation of a wound bed no new scar will be created so the derivative may regenerate the defect without new scar if you have a big scar you can use the skinTE in the first hand and the derivative in a second time to regenerate any minimal scar formation has created from the procedure of skinTE if this don't make sense why Swanson said a derivative will be used for small fine line scars without the Need of a invasive procedure minimal scar formation =fine line scar I guess
Another piece of good news, this time from a pioneering Asian country. They've managed to turn fat into a wound healing gel, that can be used toreduce the effect of Scleraxis, a gene that causes collagen fibres(scars) in healing wounds to line up parallel to one another and become more visible.
The scientist said, "We found a 'tuning knob' that controls the amount of collagen produced, instead of turning it off completely." The product could be available in five years. This was posted in 2017, so hopefully, by 2021?
Read: https://www.straitstimes.com/singapore/singapore-scientists-turn-unwanted-fat-into-wound-healing-gel
PolarityTe is up another 6% today. This is a very good news for two reason:
1) It means that investors (mainly big funds that have access to yet to be disclosed info or insiders) have had very good news.
2) More money means more funds for the company so it can expands and develop quicker
16 hours ago, Anish004 said:17 hours ago, MyBeautifulScars said:I wonder where I can get Pirfenidone.you can get it online a gel form of pirfenidone is also available named as kitoscell researches have shown it prevent scarring if applied at very early stage of wound healing
I'm guessing it does nothing on existing scars!!
2 hours ago, Anish004 said:is it true that the scars and skin component are same but only difference is scar have a densely packed collagen and hapazardly arranged????
To answer your question, scar tissue is composed of the same material as heathly skin which is collagen. Collagen in uninjured skin has a basket wave weave like pattern. In scars, collagen is aligned in one parallel direction. Too much collagen gets you raised scars. Too little collagen gets you pits or depressions in the skin.
2 hours ago, MyBeautifulScars said:To answer your question, scar tissue is composed of the same material as heathly skin which is collagen. Collagen in uninjured skin has a basket wave weave like pattern. In scars, collagen is aligned in one parallel direction. Too much collagen gets you raised scars. Too little collagen gets you pits or depressions in the skin.
this is internet answer...i read it everywhere ..on each and every site of internet they have this same definition of scar
ineed answers from some more persons on this thread
29 minutes ago, Anish004 said:this is internet answer...i read it everywhere ..on each and every site of internet they have this same definition of scar
ineed answers from some more persons on this thread2
It's the correct answer. If you don't want an internet answer, perhaps contact a dermatologist or a lecturer (in this arena) and ask them for something more in-depth.
Books and the web are vast providers of wealth. There's no harm with looking it up yourself Anish.
In other news, I found a report posted 18 hours ago regarding the future of scar removal that lists some major companies we can do our research in. Might be useful/interesting?
and
well agelessfrost and mybeautifulscars do u have any idea who run these websites which give definitions of scar as a haphazardly arranged collagen ??? the same who says vitamin E works for scars ...rubbing cocoa butter removes scars
yes this is true that scar have haphazardly arranged collagen i also know this but scar and skin have more difference than collagen arrangement i still like to hear from someone who knows better ...
and four ur kind information u cant bet on a simple definition of scar....different researches have shown different things so there are more differences than that collagen arrangement....
3 hours ago, Anish004 said:well agelessfrost and mybeautifulscars do u have any idea who run these websites which give definitions of scar as a haphazardly arranged collagen ??? the same who says vitamin E works for scars ...rubbing cocoa butter removes scars
yes this is true that scar have haphazardly arranged collagen i also know this but scar and skin have more difference than collagen arrangement i still like to hear from someone who knows better ...
and four ur kind information u cant bet on a simple definition of scar....different researches have shown different things so there are more differences than that collagen arrangement....
your rude Anish. That is what a scar is. Bundles of collagen in a tight row rather than basket weave which as strengh in different directions. Thats why scars arent as strong as they only have one direction of strengh on par with normal skin.
Yes Anish there is more differences than Collagen arrangment like hair and appendeges, which has been discussed here 100 times. Read the information yourself.
People that say vitamin e removes scars are selling products. Not science.
6 minutes ago, nikki_gargin said:your rude Anish. That is what a scar is. Bundles of collagen in a tight row rather than basket weave which as strengh in different directions. Thats why scars arent as strong as they only have one direction of strengh on par with normal skin.Yes Anish there is more differences than Collagen arrangment like hair and appendeges, which has been discussed here 100 times. Read the information yourself.
People that say vitamin e removes scars are selling products. Not science.
sorry if anyone feel i was rude
tomorrow is my exam and i am kinda depressed so i maybe somehow got harsh on words sorry for that
but yes that what kinda i say that weave pattern of collagen is just a normal definition of scar but when u in detail you find several differences between the two
like a simple definiton of cell is other thing but when u go in detail about that you find thousands of things inside a cell so i was talking about that
again sorry if i was rude
so again start talking about scarless healing
Another article on SkinTE here.
Denver Lough definitely has a way with words! (Although it does come off a bit OTT at times.)
I remember there was a poster who was trying but having no luck making contact with surgeons. Can't remember who it was?
Might be worth making contact with Dr Granick (mentioned in the article).
I'm UK based, so pointless me doing it.
Theres another Polarityte podcast conference thing on Monday. Hopefully with a new slide show presentation to see updates. I want to see Ausome's progress as his injurys were very bad poor guy.
That singapore wound healing gel looks good as well. Not available until 2022 but plaster/ dressings companies have shown interest apparently so must make a difference
Who said it's hard to contact the surgeons? Only the shills and the lazy ones who don't want you to contact them and hear your SkinTE bubbles burst say so.
I had an important tip to share, but never mind Im sure Ill regret it again. Where is a rational person to discuss it with?
Same shills who say stock priceplunges arent reflective of disappointment come back to troll about stock prices rising "undoubtedly" as a sign of...
On 5/2/2018 at 3:20 PM, golfpanther said:The price jump today is undoubtedly as a result of the conference and the OsteoTE data. Also, they closed their public offering of stock since they met their 32 million dollar goal for R&D. Investors were likely very keen on both accounts, but nothing new about SkinTE as far as I know.
On 4/16/2018 at 3:05 PM, golfpanther said:PolarityTE is cash-strapped so if they have any hope of long-term success they needed to increase their liquidity in order to continue their research and grow their business. It could be a sign of something more nefarious, but to me it's as simple as them needing money.
On 4/13/2018 at 1:14 PM, golfpanther said:It plunged because they made a public stock offering.Honestly, if any of you are on the stocktwits site and follow their ticker almost none of the investors pay attention to actual photos or releases by PolarityTE. They follow formulas for when to invest, short, play the long game etc. I was into looking at the stock price as an indicator but I think it's a bad approach to take. Ultimately, only the final results matter.
So much betting and speculation on this board - it's nauseating.
They still cant get it through their skulls that Polarity not going bankrupt does not mean their product reduces average scars. They still cant get thatminimal scarring in the medical world means a SCAR with no complications. Here entertaining 80% or 50% improvement with a product that has proven to be just a lesser crappy alternative for skin graft concerned with functionality if even that! Do all sane lurkers run upon checking this thread?