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[Sticky] Scarless Healing

 
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40
(@anish004)

Posted : 05/11/2018 8:25 pm

1 hour ago, Acnesucksforgood said:
Ok this forum is not for you to attack other members. I understand you are dealing with allot but I believe I am far worse and so many others than you will ever be. Cursing and calling me names proves you are selfish and seek help for your mental health.

Like you, I suffered from chicken pox as a youth. The disease left me scars as well including one on my neck, my stomach and my nose. I believe almost every human being has gotten chicken pox and has some sort of dent left behind from that virus. Pay attention closely and you will discover almost everyone has a chicken pox scar on their face. Stop putting yourself down about that.

Furthermore, moles are moles. There is nothing you can do about them. They are genetic and nothing you should worry about. Everyone has them. So move on. You should not touch moles because scarring occurs making your mole worse. Moles should only be a concern if they get bigger. At that point as I mentioned to you, that could be the beginning of skin cancer. Consulting a doctor to remove them to prevent further health concerns would be a good idea.

After my chicken pox, I developped staph MRSA which left me with more scarring on my back within a week. Then I got measles. This whole thing happened within a year. Also, I had multiple asthma attacks. I was also born with pectus excavatum. That's a serious condition where your sternum or chest bone grows inside your chest putting pressure on your heart. I had surgery as a teenager to push out my sternum as I would easily run out of breath. My asthma was also cured because my sternum was putting pressure on my lungs. How about getting a steel rod inserted inside you next to your heart? They had to open me up again to remove the rod. I have scars from my chest because of those surgeries alone. I also suffered a concussion as a youth due to an unrelated sports accident which opened up my head in half. I received 200 stitches and I am a proud owner of a hideous scar that runs down from my forehead to my neck.

As if I hadn't suffered enough, as a teenager I developped cystic acne on my face and acne conglobata on my back, shoulders, buttocks and thighs. My cystic acne lasted until my late twenties. It has me with multiple scarred pores or ice pick scarring on my cheeks and forehead. My jawline has multiple white slightly raised scars which are called follicular macular atrophy or popular acne scars. My back is full of these white scars. As a teenager, I was involved in another accident which left me with multiple deep wounds. They healed quite nicely but left me with scars.

I am into my late thirties and still breakout on my back. Time to time, I will breakout on my face. The pimples take months to heal often leaving more scars. Not to mention, I suffer from psoriasis, exczema and hidredinitis superitiva. How about sitting all day on massive butt boils that keep oozing blood and feeling up again. My groin keeps oozing pus.

I avoid shaving because my face gets infected by staph leading to folliculitis and massive boils that hurt. My neckline has scars from the same folliculitis causing massive infections inside my hair. The only good thing I could at least say is that I am not bald yet.

You need to grow up. Nobody cares about your blackheads or scars. Rare are those who have perfect skin. Never ever say you have it way worse than me. Never!!!

Now let's get back on topic.

I respect everyone ..maybe your scars are worser than me..that doesnt mean you have right to say those body dystrophy to others....
you can check my profile how much i reply on other posts if i feel i may be helpful to them...abd i dont get money for that...but many people here just came to take not to give a single%.......

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MemberMember
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(@anish004)

Posted : 05/12/2018 12:01 am

anyway leave the matter..i understand everyone problem
i dont know why but when i ask something many people come out of hibernation and start attacking me...
before my post they look like disappeared from earth ..

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(@creativeusername1234)

Posted : 05/12/2018 6:56 am

On 10.5.2018 at 10:22 PM, Sirius Lee said:

This one looks very promising, if it does in fact work as promised.

There are currently two clinical studies of StrataGraft in progress: a Phase 2 trial that™s expected to be completed by October 2018, and a Phase 3 trial that™s projected to finish in late 2019.

A spokeswoman for Mallickrodt said last month that the company anticipates an FDA decision on StrataGraft by 2020.

https://www.xconomy.com/wisconsin/2017/07/19/stratgrafts-skin-treatment-gets-new-fda-regenerative-med-status/?single_page=true

Thank you :)

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40
(@anish004)

Posted : 05/12/2018 9:10 am

READ THIS ABOUT SCAR REGENERATION

ok so anyone interested here i came up with something new

many people on this thread claimed removal of scar tissue with CASTOR OIL
but it didnt get much attention because this oil take 1 or 2 year to work on a scar

anyway you all must see this documentation of complete regeneration of a scar with hair follicle(you cant see hair in pics but the author wrote tht in words al...and the scar texture and depth matching to surrounding skin indicate that it regenrated)

https://skinverse.com/how-castor-oil-healed-my-scar-with-before-and-after-photos/

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68
(@rudy1986)

Posted : 05/13/2018 2:03 am

Lost hope for polarityTe?

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MemberMember
40
(@anish004)

Posted : 05/13/2018 2:53 am

47 minutes ago, rudy1986 said:

Lost hope for polarityTe?

no..i still believe in skinTe because its going to a revolutionary treatment and also its at it last stage coz they have moved to OsteoTe now..and they said they release skinTe full human trial result in 1st half of 2018..

but yes i lost hope in god and those quotes...do good you get good later....all those bullshits...

believe in skinTe

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2
(@royaume)

Posted : 05/13/2018 4:01 am

I do believe that this will be a revolutionary treatment. I mean did you see the hand results??? There was almost nothing left over and you could see the muscle and only after a few weeks everything was filled but it was still in the healing process.

Even if it is not 100 percent scarless regeneration. Even if we talk about an improvement of about 80 percent. There is nothing on the market that is able to do what they are able to do.

I think the best way would be needling + injection the paste. I have artificial acne scars, so they are not deep but I hope that skinte will help ALL of us.

What about tano? Are you still hopeful? I have read your Interview and I got hyped after it because Swanson clearly said that they are going to find a solution for smaller defects like acne scars.

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(@anish004)

Posted : 05/13/2018 10:24 am

i am sure theres something already present in nature which prevent scarring from any wound..but we human are unaware of it......

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84
(@tano1)

Posted : 05/14/2018 8:54 am

On 5/13/2018 at 4:01 AM, royaume said:

What about tano? Are you still hopeful? I have read your Interview and I got hyped after it because Swanson clearly said that they are going to find a solution for smaller defects like acne scars.

Of course. Its realistic to be prepared for under 100% regeneration, but its not far fetched to say that you cant achieve around 80% or more with the product as it stands now. The pictures show healing is happening. The hand injury we can all agree has easily achieved over 50% improvement from basically nothing left and doctors using the product have stated it is definitely working along with the patients. Theres still healing left to do and redness did take a while to fade so its going to look a lot better with some more time.

As you read from the interview, they have R&D working on a derivative specifically for cosmetic scar revisions and that does include acne scars since those are cosmetic defects.

From a business standpoint, it makes sense to start in a market that has been at best, mediocre with standard of care for the past 3 decades. They Aside from cosmetic focus, they have plenty of other products in the pipeline, but funding is one of the major obstacles in moving forward with innovation. They merged with a failing gaming company that was on the verge of bankruptcy and use the funds they had to bring out SkinTE first to the burn market where primary focus is saving a life no matter how it is done. Surpassing the mediocre standard of care for burns right now (peeled off skin grafts, physically impairing scarring, rejection of graft, a massive induced additional injury where skin was harvested) would launch their profits and their revenue would increase as they expand which they have already done to which would now give them their own source of funding and therefore can move forward with the cosmetic revisions they promised and much quicker too.

In fact, I posted just around 2 weeks ago about how the derivative products to address cosmetic defects and FDA trials along with funding would all be resolved much quicker since theyve already taken care of all of that with the success in the burn market. If you look at the giant facility they have purchased awhile back to gradually extend their product nationwide, it has reached plenty of burn centers already in such a short span of time.

Adding to what I had claimed about their production, they have just released news about their R&D obtaining a new biomedical research facility to speed up their research and development which is excellent news for all of us since we want the cosmetic outcome.

https://ir.polarityte.com/press-releases/detail/429

Let it sink in for moment:

Swanson told me back then they were already developing a derivative to address cosmetic revisions

They havent even finished a very short human clinical trial and have already bought another new facility specifically for their R&D which is where the derivative will continue to be developed.

The facility for PolarityRD is alreadyfully-functional, operational and profitable contract research organization (CRO) which is regulated and compliant under both Good Laboratory Practices (GLP) and United States Department of Agriculture (USDA) standards.

And now I cant change my font size back. Oh well. The point is after awhile you can make more sense of their intentions and what progress has been like. This is proof enough that they are set as far as funding goes and they believe that regeneration shouldnt be achieved with scaffolds and other external substrates that would require lengthy FDA trials so there is reason to suspect the FDA will be taken care of as well especially if their 3D platform technology gets approved after these current trials and Im sure it will at this point. Those are 2 major obstacles that keep innovations from coming to fruition and theyve already brushed those off and their first product hasnt even been approved yet.

Theyve also already hired a woman from John Hopkins with over a decade of experience in biomedical research for their new R&D branch. They might as well take everyone from John Hopkins because I think there have been several jumping on board.

Already an update coming soon from R&D as well. We look forward to updating the public shortly on PolarityRD and the momentum of our advancing research systems.

This current product may not get 100% regeneration, but if it can get around 80% then nothing is to stop R&D from optimizing it to bring 90-95% improvement at which point everyone here will probably celebrate. Its all just trial and error from the R&D to optimize the result to an acceptable cosmetic outcome because nothing else is standing in their way anymore.

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(@lapis-lazuli)

Posted : 05/14/2018 2:08 pm

5 hours ago, Tano1 said:
This current product may not get 100% regeneration, but if it can get around 80% then nothing is to stop R&D from optimizing it to bring 90-95% improvement at which point everyone here will probably celebrate. It™s all just trial and error from the R&D to optimize the result to an acceptable cosmetic outcome because nothing else is standing in their way anymore.

I've never understood this idea of less than 100% regeneration being an acceptable outcome. It's kind of binary I'd say; either you have new skin or you don't! :D

How am I supposed to imagine skin that is 95% regenerated? Seems like a strange idea!

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157
(@golfpanther)

Posted : 05/14/2018 2:22 pm

9 minutes ago, Lapis lazuli said:
I've never understood this idea of less than 100% regeneration being an acceptable outcome. It's kind of binary I'd say; either you have new skin or you don't! :D

How am I supposed to imagine skin that is 95% regenerated? Seems like a strange idea!

I'm still hoping for 100% regeneration, but I suspect an optimization period based on my conversations with both Dr. Swanson and Dr. Sun.

In terms of a % less than 100%, I think the difference could be many things. Density of hair follicle shafts vs. normal skin, tensile strength, amount of underlying fat tissue, width of a margin etc. A lot of that might not even matter in terms of aesthetics because if it looks like normal skin to the naked eye that's all that matters (at least I'd imagine that would be all that would matter to most on here).

Great signs for PolarityTE with the new facility and appointees. Hopefully new images of later stage healing are on their way.

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40
(@anish004)

Posted : 05/15/2018 7:25 am

17 hours ago, golfpanther said:
I'm still hoping for 100% regeneration, but I suspect an optimization period based on my conversations with both Dr. Swanson and Dr. Sun.

In terms of a % less than 100%, I think the difference could be many things. Density of hair follicle shafts vs. normal skin, tensile strength, amount of underlying fat tissue, width of a margin etc. A lot of that might not even matter in terms of aesthetics because if it looks like normal skin to the naked eye that's all that matters (at least I'd imagine that would be all that would matter to most on here).

Great signs for PolarityTE with the new facility and appointees. Hopefully new images of later stage healing are on their way.

yes what i want to see from skinTe that treated area have pores in it and normal skin texture...anything else i dont care whatever appendages or what ...

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84
(@tano1)

Posted : 05/15/2018 7:47 am

17 hours ago, Lapis lazuli said:

I've never understood this idea of less than 100% regeneration being an acceptable outcome. It's kind of binary I'd say; either you have new skin or you don't! :D

How am I supposed to imagine skin that is 95% regenerated? Seems like a strange idea!

Golfpanther pretty much nailed it. I™m talking in medical terms just as people would think full thickness would consist of all 3 layers, but it can refer to just the full epidermis and dermis. It™s possible they will be tacking on their own percentage improvements just like others have such as Fraxel.

You have other factors that can be invisible to the eye such as the margin, presence of the basket weave pattern, subcutaneous fat tissue, etc.. that may not have regenerated fully, but it™s not notable  to the one desiring a satisfactory cosmetic result. For the cosmetic group, they™ll be fine as long as it vanishes and everything looks normal. If you swung with either 100% skin or no skin at all, that would be fine, but the market won™t be slowing down with an exponentially better improvement than anything else that™s on the market right now. 

We™ll end up with a choice if any product (nothing to do with Polarity) comes out and provides nearly full regeneration. Would you rather sport a scar that sits on your body and cries out to the world that they™re here? Or would you rather sport a scar that™s pigmented to keep the eye from focusing on a discolored tone on your body and the reconstructive instruction is flush with the skin so a tethering effect is also in-perceivable even from an angled view of your face therefore making your scar virtually invisible to the eye? 

I™ll settle for 90% no problem. They can take the rest of my life to figure out the last 10 while I walk around with 0 people ever asking what happened to me since they can™t see a defect in the first place. 

Just keep in mind that realistically, any company including Polarity can fail to optimize their product and you could be left with only what they were able to do in the beginning. Binary won™t get us progress though. Even Dr. Sun and Maksim Plikus believe optimization is an implementable and necessary step to producing the goal. Polarity, Sunogel, and Cotsarelis all went through optimization even in pre-clinicals with more improved versions of their research being tested until they produced something that the people may just want.

When you think down to a molecular level and have stem cells, bioprinting and gene modification etc... all added in, the box is much much bigger.

If one of these current teams doesn™t solve it, I personally believe fully that Bioprinting and Gene Modification will without a doubt, but that™s a ways away still. 

Did I just get slightly off topic on a post, but yet stay on topic in the thread? Yes I did :smileys_n_people_8:

 

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68
(@nikki_gargin)

Posted : 05/15/2018 9:55 am

2 hours ago, Anish004 said:
19 hours ago, golfpanther said:
I'm still hoping for 100% regeneration, but I suspect an optimization period based on my conversations with both Dr. Swanson and Dr. Sun.

In terms of a % less than 100%, I think the difference could be many things. Density of hair follicle shafts vs. normal skin, tensile strength, amount of underlying fat tissue, width of a margin etc. A lot of that might not even matter in terms of aesthetics because if it looks like normal skin to the naked eye that's all that matters (at least I'd imagine that would be all that would matter to most on here).

Great signs for PolarityTE with the new facility and appointees. Hopefully new images of later stage healing are on their way.

yes what i want to see from skinTe that treated area have pores in it and normal skin texture...anything else i dont care whatever appendages or what ...

trust me. You need appendages for sweat and sebum or theres no point to the pores. Thats what polarized healing is all about x

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80
(@sniffy)

Posted : 05/16/2018 5:13 am

Do yourself a favour and check out Facebook page "The recovery for ausome"..

Actual skinte patient with details of healing but no photos. He had a wound down to bone and it now has skin over it and he has sensation in skin and sweat glands in new skin.

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MemberMember
40
(@anish004)

Posted : 05/16/2018 7:06 am

1 hour ago, Sniffy said:

Do yourself a favour and check out Facebook page "The recovery for ausome"..

Actual skinte patient with details of healing but no photos. He had a wound down to bone and it now has skin over it and he has sensation in skin and sweat glands in new skin.

I really believe SkinTe is going to be our saviour.......

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2
(@royaume)

Posted : 05/16/2018 4:16 pm

Now let us explain why we are running in circles in excitement about PolarityTE and the difference they have made in Austin's recovery! Their process allows surgeons to take a full thickness donor harvest about the size of a postage stamp so no scraping the same areas over and over. Austin had a few stitches and was sore for about a day but the harvesting was much less painful than with split-thickness donation.

Here is where things get cool:

For the SkinTE process, the surgeon sends the full thickness harvest off to PolarityTE, they grind it up into skin seed jelly (less than technical but you can read all about the medical version on their webpage posted below), and then jelly is returned the next day and the surgeons use it to cover large areas of the body. One harvest covered Austin's right arm. One harvest covered his left arm. The last harvest covered both of his sides and the back of his thigh.

We giggle about calling it skin seeds but that is exactly what it reminds us of, because once the jelly gets spread over the wound, it adheres and starts growing skin just like plants grow and spread out. After a week, we could actually see it start to grow. At the one month mark, it had regenerated to the point where it fully covered Austin's exposed bone areas. Six weeks in and Austin's right arm has almost no pain, he can feel water being poured over his arm, and the skin is sweating. PolarityTE's SkinTE allows the skin to regenerate with sweat glands and hair follicles and best of all.. far less scarring!!

This is why we want to tell as many people as possible! We know how PolarityTE has changed Austin's life. Their technology can go way beyond burn patients and can be used for a variety of forms of tissue regeneration including skin, bone, and even nerves. This is HUGE! We tear up thinking about how many more lives they will change for the better. We seriously can not thank them enough.

Great news!

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6
(@jac3)

Posted : 05/16/2018 9:09 pm

4 hours ago, royaume said:

and best of all.. far less scarring!!

This is awesome! I am genuinely elated for the people that it can and will help.
But it says it pretty clearly here - 'far less scarring'. It doesn't say 'no scarring'. I don't mean to undermine SkinTE's achievements, but this thread is and has always been about healing without scars. I just don't think SkinTE is going to achieve that, despite how much we hang on to the idea that it will. None of the results thus far have indicated scar free healing. Again, they are amazing, yes. But they aren't scar free.

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80
(@sniffy)

Posted : 05/16/2018 11:13 pm

5 hours ago, jac3 said:
This is awesome! I am genuinely elated for the people that it can and will help.
But it says it pretty clearly here - 'far less scarring'. It doesn't say 'no scarring'. I don't mean to undermine SkinTE's achievements, but this thread is and has always been about healing without scars. I just don't think SkinTE is going to achieve that, despite how much we hang on to the idea that it will. None of the results thus far have indicated scar free healing. Again, they are amazing, yes. But they aren't scar free.

The problem is not the results being 100% perfect new skin but rather people trying to compare whats currently happening with these patients to Acne scars...these patients with wounds down to muscle and bone are not even in same ball park as us, not even the same League. We are hearing positive results yes but Im waiting to see it tackle much smaller problems like small acne scars with derivative applications for purely cosmetic goals. Sweat Glands, sensation, hair follicles etc so early after such deep injuries is huge and an indication of at least better appearing skin without scar tissue present.

If "Far less scarring" means getting skin back to 80-90% for acne scars then its going to make alot of people with acne scars very happy. A small acne scar replaced or treated with SkinTe you would think heals over with "far less" scarring with some appendages and basically becomes invisible to the eye. That's what we hope anyway...i can find a small acne scar and imagine it with far less scarring and it would basically vanish. Remembering Skinte is designed to regenerate new skin not aided scarring.

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40
(@anish004)

Posted : 05/17/2018 1:10 am

1 hour ago, Sniffy said:
The problem is not the results being 100% perfect new skin but rather people trying to compare whats currently happening with these patients to Acne scars...these patients with wounds down to muscle and bone are not even in same ball park as us, not even the same League. We are hearing positive results yes but Im waiting to see it tackle much smaller problems like small acne scars with derivative applications for purely cosmetic goals. Sweat Glands, sensation, hair follicles etc so early after such deep injuries is huge and an indication of at least better appearing skin without scar tissue present.

yes i agree our scarring from pox and acne goes maximum down to hypodermis

these results are from deep down injuries to muscle and bones

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68
(@rudy1986)

Posted : 05/17/2018 3:11 am

People keep saying our wound from acne or pox is not deeper than them...

i dont get it, by the end, it doesnt matter at all, our depth is not different than theirs..

They are down to full thicness? We are tooo.. why? Because we inevitably have to excise our minimal depth wpund to full thickness.. no difference people

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(@damnboy)

Posted : 05/17/2018 4:24 am

1 hour ago, rudy1986 said:

People keep saying our wound from acne or pox is not deeper than them...

i dont get it, by the end, it doesnt matter at all, our depth is not different than theirs..

They are down to full thicness? We are tooo.. why? Because we inevitably have to excise our minimal depth wpund to full thickness.. no difference people

Lol they said down to the bone and you say is the same with scars in the middle layer of the skin

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68
(@rudy1986)

Posted : 05/17/2018 5:15 am

Please read completely what i stated, i said that even though we are more shallow in depth, we have to eventually excise it to full thickness

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80
(@sniffy)

Posted : 05/17/2018 6:55 am

1 hour ago, rudy1986 said:

Please read completely what i stated, i said that even though we are more shallow in depth, we have to eventually excise it to full thickness

We dont yet know if Excision will be the preference for Acne scars. If its regenerating skin close to 100% its no problem i guess. Otherwise a less invasive approach is the goal and if repeat treatments are needed so be it. It comes down to removing scar tissue completely or just breaking it down to create a new wound. My understanding is the scar tissue is removed with SkinTe at least for large graft areas which makes sense but small defects with surrounding good skin we await their plans.

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47
(@damnboy)

Posted : 05/17/2018 7:11 am

1 hour ago, rudy1986 said:

Please read completely what i stated, i said that even though we are more shallow in depth, we have to eventually excise it to full thickness

No they don't have to excise full thickness they will excise only the defect read the conservation of Swanson with Tano

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