Acne.org Products
Some dates that might reveal info on PolarityTE:
33 minutes ago, Raster said:Some dates that might reveal info on PolarityTE:
SkinTE a human cellular and tissue-based product derived from a patients own skin to regenerate full-thickness, functionally-polarized skin with all its layers (epidermis, dermis and hypodermis) and appendages, including hair follicles and glands. SkinTE, for the repair, reconstruction and replacement of full-thickness skin, has been used in the treatment of chronic wounds during the limited-market release, and it has the potential to change the wound care field by providing a novel, full-thickness treatment option.
They are not backing away from their claims at least.
1 hour ago, Anish004 said:when Acell grown a finger tip..and currently used in regenerating scalp scar to grow hair than why its not used for face scars ????
whats the matter i still cant figure out
I don't know what you're asking, but I assume the purpose of the scalp regeneration was to grow hair as you said yourself, not elimination of marks. 2 different things. And, growing body parts is another functional application.
1 hour ago, surgical scar said:I don't know what you're asking, but I assume the purpose of the scalp regeneration was to grow hair as you said yourself, not elimination of marks. 2 different things. And, growing body parts is another functional application.
you need to do research on Acell..Acell once regenerated lost finger tip and full thickness skin after surgery on nose...
4 hours ago, Anish004 said:5 hours ago, surgical scar said:I don't know what you're asking, but I assume the purpose of the scalp regeneration was to grow hair as you said yourself, not elimination of marks. 2 different things. And, growing body parts is another functional application.you need to do research on Acell..Acell once regenerated lost finger tip and full thickness skin after surgery on nose...
so?
17 hours ago, Anish004 said:when Acell grown a finger tip..and currently used in regenerating scalp scar to grow hair than why its not used for face scars ????
whats the matter i still cant figure out
Acell is probably one of those companies making false claims to go after vulnerable people looking for solutions. The whole claim that a fingertip was regenerated goes back to 2007 and I believe Dr. Oz had talked about them on Oprah, giving the company some sort of exposure.
Issue here is that 10 years have passed and nobody talked about them ever since. Apparently, all they had to do was take a pig bladder, extract some cells from it, what they can call the extra cellular matrix and grind it down to a powder. Then the powder is applied to a fresh injury and it is said to regenerate a severed finger.They never said anything about scarless wound healing. One would assume that because the lost limb is regenerated, then a severe skin injury will result in scarless healing also.
However, if their claims were true afterall and they were able to regenerate missing fingers, why haven't we heard anything about them in the last 10 years.
I would like also to inform you that humans do regenerate lost fingertips. Some children have the ability to do so, older people don't. The conditions have to be right. Essentially, the injury or the cut must not extend beyond the nail ending. A missing piece of finger like a fingertip will regenerate in children under 10 above the nail root or if a piece of nail remains. The same applies for toes.
A missing part with no nail root results in a permanent loss of that piece of finger. The regenerated part is not perfect. For example, there may no fingerprints and the fingertip looks a bit weird instead of round but I guess it's better than not having a fingertip at all. The nail also doesn't look perfect.
Our bodies have this ability of having a lot of unused stem cells at the extremities of our fingers and toes. When an injury happens and we lose a small part like fingertip or toetip, our bodies regenerate this missing piece. If the injury extends past the nail and there is no part of nail remaining, then our bodies won't regenerate the missing part.
Hate to rain on people's parade but i have been to Polarity's facebook page and some of the posters don't think it would work getting rid of acne scars.Polarity has not said anything on acne scars.I asked on Sunogel's facebook page and they said it should work on acne scars.I am not a expert on these newer treatments but i spent over 30k on stuff that didn't do squat.
On 4/22/2018 at 5:01 PM, Acnesucksforgood said:Acne is not caused by testosterone. It seems that in today's society that this hormone is linked to all kinds of ridiculous claims from some groups who try to diminish it's importance. Testosterone is the key to species survival.To be fair, acne is caused by p. acnes. A natural occurring organism present on all human skin. Around puberty, testosterone kicks in both sexes and skin overproduces oil. For some people, p.acnes is in overabundance and feeds off the oil creating skin infections and creating an inflammatory response. Most people get occasional blackheads and whiteheads due to oil clogging skin pores. These go away quickly with no consequences. This is your normal acne most teens will experience.
For some, P. acnes will infect whiteheads and blackheads. This will cause inflammation as the body sends in white cells to kill p.acnes. For most, the inflammation goes away quickly and the pimple heals fast with just hyperpigmentation which will go away after a year. For others, the body overreacts causing bigger inflammation and more tissue destruction as p.acnes multiplies and the infectious worsen.
The key to curing acne is to reduce inflammation and to stop the overgrowth of p.acnes. Benzoyl peroxide kills p.acnes and thus limits the overgrowth of the bacteria. Exfoliating helps with the overproduction of oil however this makes the body generate more oil. Anxiety makes the body secrete other enzymes and hormones which generate more sweat and oil.
The issue with acne is that for some, the body seems to be intolerant to too much p.acnes and won't tolerant bacterial byproducts of the organism causing more inflammation and sores.
Some foods seem to direct the body to release even more oil. Some of this oil may contain more elements from certain foods we eat that p.acnes loves to feast on, creating the perfect environment for the bacteria. Avoiding certain foods could help lessen the intensity of the breakouts. Some people come on here claiming a vegan diet cured them from their acne but it is different from person to person. Everyone must experiment on their own to see which types of foods cause more breakouts for them.
The scarring that results is from our own body as it destroys healthy tissue in its fight against p.acnes, what we call inflammation.
Acne can also be caused by other conditions such as food allergies, other organisms like Demodex, staph MSRA, folliculitis, fungal infections and underlying hormonal imbalances like too much Estrogen or too much Androgens being released by undiagnosed tumours.
Few will claim that testosterone causes the more severe forms of acne like acne conglobata or acne fulfimans but we are only starting to scratch the surface as to why testosterone is not the only culprit of acne.
Well you are wrong....i tried everything to get rd of my acne....i was one of the first people on accutane. Didn't work......i went on Spironolactone and it cleared up my skin magically. As long as i take Spiro my skin will be clear because it is a anti-androgen that blocks T. Will never lose hair either. Sorry shit like Proactive who's active ingredients are BP didn't do crap for me and is way overpriced.
26 minutes ago, SimpleMutton said:We're in May and still no good pic showed.
Starting to get a bit disappointed tbh
Um, its April still by my calendar.
PolarityTE said they would be releasing photos and results throughout the first half of the year and they still have two months for that.
It may or may not be results we want but at least give them through June before we all decry them. Theyve met all their indicated timelines thus far.
1 hour ago, nikkigirl said:Hate to rain on people's parade but i have been to Polarity's facebook page and some of the posters don't think it would work getting rid of acne scars.Polarity has not said anything on acne scars.I asked on Sunogel's facebook page and they said it should work on acne scars.I am not a expert on these newer treatments but i spent over 30k on stuff that didn't do squat.
Well you are wrong....i tried everything to get rd of my acne....i was one of the first people on accutane. Didn't work......i went on Spironolactone and it cleared up my skin magically. As long as i take Spiro my skin will be clear because it is a anti-androgen that blocks T. Will never lose hair either. Sorry shit like Proactive who's active ingredients are BP didn't do crap for me and is way overpriced.
Again, testoreone does not cause acne. It is the bacteria p.acnes that causes it. Testoreone makes your oil glands produce more oil and the bacteria proliferates in it infecting your pores. Taking Spiro means that you block androgens like T. and your skin doesn't produce so much oil and keeps P.acnes at bay. Again stop blaming T. for your skin woes. Without T., men wouldn't be men. Women wouldn't be able to reproduce. T. is not so bad after all.
In the end, I feel you have a deep hatred of T. which represents anything manly. Spiro is something some men take to become effeminate into their transition to womanhood. Society is more accepting of this now but society cannot continue in this path of feminizing men. T does causes baldness in more than half of older men but it is something that is accepted. Baldness itself is not a disease but rather a sign of aging. There are cheap hair transplants that men can opt for now anyways. Many men are also lucky to keep their hair until they reach 90. You can't blame T. here either. You can say that some men have good hair genes.
Men have it way worse with acne than women do because of what I mentioned above in their teenage years. For most men, their acne tends to die down by their thirties. Women seem to get hit by acne more and more in their early twenties nowadays and lasts a lifetime. It is not T. that is causing this. It is stress, a high glycemic diet, allergies, other pathogenic organisms and staphylococcus infections. Also, older women tend to have hormone imbalances in their older years producing more Estrogen which causes breakouts around the mouth.
If anything blame P.acnes not T. The best thing to do would be to develop a medication specifically targeting P.acnes. P.acnes actually helps our skin but too much of it causes our body to attack it which results in inflammation and scarring once the pimples heal. Evolution has selected for scarring and not complete regeneration to close wounds fast to prevent infection.
So a medication to stop the proliferation of p.acnes and to keep pores unclogged without any side effects would be the best thing to do. Secondly, reprogramming scar tissue into normal tissue with hair follicles and the basket wave pattern would be a start. Researchers are working on this but a lot of work needs to be done before something good can be available on the market.
https://www.sciencealert.com/scientists-figure-out-how-to-make-wounds-heal-without-scars
Scientists Have Figured Out How to Make Wounds Heal Without Scars
Like it never happened.
And while there'snot a whole lotthat can be done for scars that are already there, in 2017 researchers figured out how to make fresh wounds heal as normal, regenerated skin, instead of the usual scar tissue - something that was previously thought to be impossible in mammals.
"Essentially, we can manipulate wound healing so that it leads to skin regeneration rather than scarring,"said one of the team, George Cotsarelis, chair of the Department of Dermatology at the University of Pennsylvania last year.
"The secret is to regenerate hair follicles first. After that, the fat will regenerate in response to the signals from those follicles."
If you've ever wondered why scar tissue looks so different from regular skin, it's because scar tissue doesn't contain any fat cells or hair follicles.
The type of skin that regenerates over a small, superficial cut is filled with fat cells calledadipocytes, just like the skin you were born with, which means the two will eventually blend into each other once the wound has healed.
But scar tissue is made up almost entirely of cells calledmyofibroblasts, and doesn't contain any fat cells at all. So instead of blending into the surrounding skin once the wound has fully healed, it looks completely different - permanently.
The same goes for ageing skin - as we age,we lose our adipocytes, which leads to discolouration and deep, irreversible wrinkles.
But scientists have discovered that existing myofibroblasts can actually be converted into adipocytes, which suggests that as a wound is healing, scar tissue could be converted to regenerated skin instead - something that scientists thought could only be possible in fish and amphibians.
"The findings show we have a window of opportunity after wounding to influence the tissue to regenerate rather than scar,"said one of the team, Maksim Plikus, from the University of California, Irvine.
3 hours ago, Sirius Lee said:https://www.sciencealert.com/scientists-figure-out-how-to-make-wounds-heal-without-scarsScientists Have Figured Out How to Make Wounds Heal Without Scars
Like it never happened.
And while there'snot a whole lotthat can be done for scars that are already there, in 2017 researchers figured out how to make fresh wounds heal as normal, regenerated skin, instead of the usual scar tissue - something that was previously thought to be impossible in mammals.
"Essentially, we can manipulate wound healing so that it leads to skin regeneration rather than scarring,"said one of the team, George Cotsarelis, chair of the Department of Dermatology at the University of Pennsylvania last year.
"The secret is to regenerate hair follicles first. After that, the fat will regenerate in response to the signals from those follicles."
If you've ever wondered why scar tissue looks so different from regular skin, it's because scar tissue doesn't contain any fat cells or hair follicles.
The type of skin that regenerates over a small, superficial cut is filled with fat cells calledadipocytes, just like the skin you were born with, which means the two will eventually blend into each other once the wound has healed.
But scar tissue is made up almost entirely of cells calledmyofibroblasts, and doesn't contain any fat cells at all. So instead of blending into the surrounding skin once the wound has fully healed, it looks completely different - permanently.
The same goes for ageing skin - as we age,we lose our adipocytes, which leads to discolouration and deep, irreversible wrinkles.
But scientists have discovered that existing myofibroblasts can actually be converted into adipocytes, which suggests that as a wound is healing, scar tissue could be converted to regenerated skin instead - something that scientists thought could only be possible in fish and amphibians.
"The findings show we have a window of opportunity after wounding to influence the tissue to regenerate rather than scar,"said one of the team, Maksim Plikus, from the University of California, Irvine.
i read this a fee months ago but im abit meh coz i have a scarred 2inch by 6 inch block on my leg with all my hairs left in place so that doesnt make sense to me.
Also i noticed Polarity always say 'functional' never aestetically excellent or what ever. I really dont think polarity is gonna be the one for scar revision just functional tissue wound cover..which is fantastic for just that. I hope im wrong though. If pics arr aestetically excellent ill get excited.
6 hours ago, Acnesucksforgood said:Again, testoreone does not cause acne. It is the bacteria p.acnes that causes it. Testoreone makes your oil glands produce more oil and the bacteria proliferates in it infecting your pores. Taking Spiro means that you block androgens like T. and your skin doesn't produce so much oil and keeps P.acnes at bay. Again stop blaming T. for your skin woes. Without T., men wouldn't be men. Women wouldn't be able to reproduce. T. is not so bad after all.
True that. Low testosterone is not only antithetical to human reproduction (here I'm not merely talking about Darwinian evolution but low sexual urge and,more specifically, erectile dysfunction), it can cause scores of undesirable effects. Male pattern baldness, as already mentioned, is one. Osteoporosis is another. How about severe mood changes that can bring depression? It doesn't just make you girly, it will make you feeling suicidal (according to those on testosterone replacement therapy).
2 hours ago, nikki_gargin said:i read this a fee months ago but im abit meh coz i have a scarred 2inch by 6 inch block on my leg with all my hairs left in place so that doesnt make sense to me.
You might want to look again. My sources tell me hairs don't grow on scars. That's not to saythat hairfollicles from the normal skin adjacent to thescar tissue cannot penetrate and grow out through the scar. Yeah, that sounds loony but that's how the story goes.
many people on this forum claimed that Copper peptides on wound help in skin regeneration( decorin related)
and decorin is the discussed thing to do scarless healing
does anybody know deeply about that
copper peptide mechanism of skin regeneration by decorin and other components ..inhibitions
6 hours ago, Anish004 said:i also have growing hair and pimples on a hypertrophic scar what that mean...the scar is even raised ??????what it all mean ??????
Scars don't have hair however if the injury didn't destroy the hair follicules, then most likely than not, hair will grow from the scar. This also means that the hair follicules can get clogged and you get pimples on your scar. The skin has 3 main parts: the epidermis, dermis and fat. Scars form in the dermis. The epidermis regenerates. It is composed mostly of dead skin cells. Hair follicules and sweat glands lie deep in the dermis. If your injury is deep, it will scar. Everytime you bleed you have high chances of getting a scar. Minor cuts or scrapes don't scar generally because it doesn't extend deep in the dermis and there are many stem cells there or healthy skin cells which can divide fast and close the wound. It is that simple. A wound less than 2 mm deep in the dermis will not scar. In the case with facial acne, the inflammation goes deep in the dermis as your body fights bacteria and the end result is a dent in your skin as the fat tissue is lost forever. For body acne, the body over-repairs itself giving you hypertrophic scars.
12 hours ago, Sirius Lee said:https://www.sciencealert.com/scientists-figure-out-how-to-make-wounds-heal-without-scarsScientists Have Figured Out How to Make Wounds Heal Without Scars
Like it never happened.
And while there'snot a whole lotthat can be done for scars that are already there, in 2017 researchers figured out how to make fresh wounds heal as normal, regenerated skin, instead of the usual scar tissue - something that was previously thought to be impossible in mammals.
"Essentially, we can manipulate wound healing so that it leads to skin regeneration rather than scarring,"said one of the team, George Cotsarelis, chair of the Department of Dermatology at the University of Pennsylvania last year.
"The secret is to regenerate hair follicles first. After that, the fat will regenerate in response to the signals from those follicles."
If you've ever wondered why scar tissue looks so different from regular skin, it's because scar tissue doesn't contain any fat cells or hair follicles.
The type of skin that regenerates over a small, superficial cut is filled with fat cells calledadipocytes, just like the skin you were born with, which means the two will eventually blend into each other once the wound has healed.
But scar tissue is made up almost entirely of cells calledmyofibroblasts, and doesn't contain any fat cells at all. So instead of blending into the surrounding skin once the wound has fully healed, it looks completely different - permanently.
The same goes for ageing skin - as we age,we lose our adipocytes, which leads to discolouration and deep, irreversible wrinkles.
But scientists have discovered that existing myofibroblasts can actually be converted into adipocytes, which suggests that as a wound is healing, scar tissue could be converted to regenerated skin instead - something that scientists thought could only be possible in fish and amphibians.
"The findings show we have a window of opportunity after wounding to influence the tissue to regenerate rather than scar,"said one of the team, Maksim Plikus, from the University of California, Irvine.
This is something that was talked about extensively on this forum last year however nothing new can be reported from this research for the last year and a half. The reseachers had said they would start conducting clinical trials but they may not want to go ahead with it. Either way, it can take a long time for them to get the funding and start human trials. Problem is they don't have much to say about existing scars.
27 minutes ago, Acnesucksforgood said:Scars don't have hair however if the injury didn't destroy the hair follicules, then most likely than not, hair will grow from the scar. This also means that the hair follicules can get clogged and you get pimples on your scar.
you are more than 10000% correct the raised scar i have also grow pimple on it
is it mean that the injury was not too deep and this scar is easily treatable ?
15 hours ago, Acnesucksforgood said:Again, testoreone does not cause acne. It is the bacteria p.acnes that causes it. Testoreone makes your oil glands produce more oil and the bacteria proliferates in it infecting your pores. Taking Spiro means that you block androgens like T. and your skin doesn't produce so much oil and keeps P.acnes at bay. Again stop blaming T. for your skin woes. Without T., men wouldn't be men. Women wouldn't be able to reproduce. T. is not so bad after all.In the end, I feel you have a deep hatred of T. which represents anything manly. Spiro is something some men take to become effeminate into their transition to womanhood. Society is more accepting of this now but society cannot continue in this path of feminizing men. T does causes baldness in more than half of older men but it is something that is accepted. Baldness itself is not a disease but rather a sign of aging. There are cheap hair transplants that men can opt for now anyways. Many men are also lucky to keep their hair until they reach 90. You can't blame T. here either. You can say that some men have good hair genes.
Men have it way worse with acne than women do because of what I mentioned above in their teenage years. For most men, their acne tends to die down by their thirties. Women seem to get hit by acne more and more in their early twenties nowadays and lasts a lifetime. It is not T. that is causing this. It is stress, a high glycemic diet, allergies, other pathogenic organisms and staphylococcus infections. Also, older women tend to have hormone imbalances in their older years producing more Estrogen which causes breakouts around the mouth.
If anything blame P.acnes not T. The best thing to do would be to develop a medication specifically targeting P.acnes. P.acnes actually helps our skin but too much of it causes our body to attack it which results in inflammation and scarring once the pimples heal. Evolution has selected for scarring and not complete regeneration to close wounds fast to prevent infection.
So a medication to stop the proliferation of p.acnes and to keep pores unclogged without any side effects would be the best thing to do. Secondly, reprogramming scar tissue into normal tissue with hair follicles and the basket wave pattern would be a start. Researchers are working on this but a lot of work needs to be done before something good can be available on the market.
Then why are you here? If you are so manly just put up with your scars and acne.....if it bothers you.....it means you are sensitive..something a REAL man of your stature would never allow to happen.
9 hours ago, Sirius Lee said:True that. Low testosterone is not only antithetical to human reproduction (here I'm not merely talking about Darwinian evolution but low sexual urge and,more specifically, erectile dysfunction), it can cause scores of undesirable effects. Male pattern baldness, as already mentioned, is one. Osteoporosis is another. How about severe mood changes that can bring depression? It doesn't just make you girly, it will make you feeling suicidal (according to those on testosterone replacement therapy).
You might want to look again. My sources tell me hairs don't grow on scars. That's not to saythat hairfollicles from the normal skin adjacent to thescar tissue cannot penetrate and grow out through the scar. Yeah, that sounds loony but that's how the story goes.
That is true......you can try to control your acne but if you shut off Testosterone..your skin will clear up....just suck it up...enjoy your pimples and scars and be a man.
On 4/26/2018 at 4:53 PM, CollegeKidd said:I wouldn't recommend Accutane to my worst enemy
Then don't take it......it has help a lot of people out. It doesn't help the root problem which is hormones mainly testosterone but it is suppose to shrink oil glands.....doesn't work for everybody.