bleh

Interesting article about the antiscarring drug of birchbiomed: http://www.ceocfointerviews.com/interviews/BirchBioMed18.htm

they said amniotic fluid right ?
there are already many clinics in world who uses amniotic fluid for scar theray
by first injuring the scar by laser and applying amniotic fluid
...

The topic here is scarless healing - not treatment for acne.

Stay on topic!

Frasier i want to prevent scarrig from my acne thats why i asked and by the way you are talking like from months we are only talking here about scars i have seen people fighting with each other in conversation ...some diet tipd to prevent acne..so why u targeted me when i asked ??
looks like you have achieved scarless thing...go treat your scars ...you are high

14 minutes ago, Anish004 said:

Frasier i want to prevent scarrig from my acne thats why i asked and by the way you are talking like from months we are only talking here about scars i have seen people fighting with each other in conversation ...some diet tipd to prevent acne..so why u targeted me when i asked ??
looks like you have achieved scarless thing...go treat your scars ...you are high

So other people going off topic gives you justification to go off topic? Should people ask how to stop themselves from falling down, since that would prevent scarring as well? It's not just this time either. You're always asking questions that can easily be answered by a quick google search. You could also just make another thread instead of making people go through your irrelevant posts and waste their time when they're looking for discussion on scarless healing.

this is why we all suffering from scars and hoping to die beacuse we cant understand other problems...just think of own .
.i asked here because i posted my problem in a new topic but nobody replied and also i am not getting away from scarless healing..i already know some things which do scarless healing of skin upto 90% and i am more interested in skinTe than you all..who have full of doubts on skinTe
but while waiting for skinTe full results ..solving other problem shouldnt trouble you ..anyway its ur life i dont interfere

tired of some selfish people here who just think of themselves and dont want to help other and thats your sin and thats why we all suffering from these scars...atleast from my point of view

thanx to some members like nikki gargain,Tano,Rez and some more i cant remember

I see you went right back to finding more people to fight with

On 4/24/2018 at 5:55 AM, Anish004 said:

this is why we all suffering from scars and hoping to die beacuse we cant understand other problems...just think of own .
.i asked here because i posted my problem in a new topic but nobody replied and also i am not getting away from scarless healing..i already know some things which do scarless healing of skin upto 90% and i am more interested in skinTe than you all..who have full of doubts on skinTe
but while waiting for skinTe full results ..solving other problem shouldnt trouble you ..anyway its ur life i dont interfere

tired of some selfish people here who just think of themselves and dont want to help other and thats your sin and thats why we all suffering from these scars...atleast from my point of view

thanx to some members like nikki gargain,Tano,Rez and some more i cant remember

I don't really understand what you're saying, but yes you are being selfish by posting on this thread without doing the most basic research, and by posting questions that are unrelated to the topic. You're going to post an off-topic question here because nobody replied elsewhere? That's a waste of everybody's time dude. And wasting everybody's time because you can't put in the time to research or find an appropriate place to ask is selfish. Nobody clicks on this thread to keep themselves up to date with [censored] off-topic and half-baked questions. Likewise, nobody clicks on this thread in anticipation of what brilliant gibberish [censored] to enlighten the other users who *clearly* are being scammed. Most of us just want logical discussions on developments that might help achieve scarless healing.

Back on topic - PolarityTE's presentation has higher resolution pictures of the wrist and leg injuries. You can zoom in up to 500% without the photos pixelating too much.

an acne scar sufferer dont want to help other person to prevent scarring ..i already said i asked many timed on other topics and i dont got any help and talk about internet which is full of different opinions and confuse u...so why not ask someone who suffered from this thing and know better about this

thats why u and i are scar sufferer and cutted from social emotional life

Rickeydog i have more belief in skinTe than you
and i think that helping other about acne dont showthat your interest in scarless thing has reduced

i know how to solve my problem ..thats why i showefsalicylic acid gel
i just wanna confirm that is it right approach

and u talk about internet basic research i bet i know more than you about scarless healing just by my internet researches

SORRY IF ANYBODY HURTED BY MY ACNE POST..YES THIS IS A SCARLESS HEALING THREAD and asking about acne is a crime here

sorry guyz continue to your scarless healing ..i will not bother you guys anymore

On 4/24/2018 at 3:49 AM, RickeyDog1989 said:

I don't really understand what you're saying, but yes you are being selfish by posting on this thread without doing the most basic research, and by posting questions that are unrelated to the topic. You're going to post an off-topic question here because nobody replied elsewhere? That's a waste of everybody's time dude. And wasting everybody's time because you can't put in the time to research or find an appropriate place to ask is selfish. Nobody clicks on this thread to keep themselves up to date with Anish004's off-topic and half-baked questions. Likewise, nobody clicks on this thread in anticipation of what brilliant gibberish 

Just so you know I'm reporting everyone who starts fights and particularly brings other members into their lame fits because they're too weak in their own tantrums and need to seek attention from random members...so go on

Guess what...nobody comes here to read your rude gibberish 

On 4/24/2018 at 3:52 AM, Anish004 said:

an acne scar sufferer dont want to help other person to prevent scarring ..i already said i asked many timed on other topics and i dont got any help and talk about internet which is full of different opinions and confuse u...so why not ask someone who suffered from this thing and know better about this

thats why u and i are scar sufferer and cutted from social emotional life

Rickeydog i have more belief in skinTe than you
and i think that helping other about acne dont show that your interest in scarless thing has reduced

i know how to solve my problem ..thats why i showef salicylic acid gel
i just wanna confirm that is it right approach

and u talk about internet basic research i bet i know more than you about scarless healing just by my internet researches

SORRY IF ANYBODY HURTED BY MY ACNE POST..YES THIS IS A SCARLESS HEALING THREAD and asking about acne is a crime here

sorry guyz continue to your scarless healing ..i will not bother you guys anymore

You don't need to leave because of some rude mental that goes around shouting "stay on topic" and thinking he/she owns the forum. Let them take a walk... 

40 minutes ago, Anish004 said:

an acne scar sufferer dont want to help other person to prevent scarring ..i already said i asked many timed on other topics and i dont got any help and talk about internet which is full of different opinions and confuse u...so why not ask someone who suffered from this thing and know better about this

thats why u and i are scar sufferer and cutted from social emotional life

Rickeydog i have more belief in skinTe than you
and i think that helping other about acne dont showthat your interest in scarless thing has reduced

i know how to solve my problem ..thats why i showefsalicylic acid gel
i just wanna confirm that is it right approach

and u talk about internet basic research i bet i know more than you about scarless healing just by my internet researches

SORRY IF ANYBODY HURTED BY MY ACNE POST..YES THIS IS A SCARLESS HEALING THREAD and asking about acne is a crime here

sorry guyz continue to your scarless healing ..i will not bother you guys anymore

Having scars is not a big deal. If you really feel like you are 'cutted from social emotional life' because of acne scarring, you need to realize that there are people out there with much much worse causes of suffering that are not 'cutted from social emotional life'. And if you know so much about scarless healing, good for you. Just realize that you are being selfish, which is a 'sin' according to you, by derailing the thread and asking half-baked questions on topics that you supposedly know so much about. Also, being selfish and having scars are irrelevant. It's illogical to think that unrelated things are related. Being logical is necessary for understanding what you study. Perhaps this is why, despite having studied so much about scarless healing, you continue to post low-effort, one-sentence questions about the most immediately available topics that barely make sense, contribute nothing substantial to the thread, and just take up space. Maybe try to be logical before spewing whiny, irrelevant, and illogical posts.

@surgical scarJudging by your post history, you don't think you're the most frequent contributor to starting fights and throwing tantrums? Asking posters who continue to post off-topic questions since months back to stay on topic, and explaining the reasons why others would appreciate their stopping derailing the thread is 'gibberish'? Ironic coming from you. Do you understand how many pages people of irrelevant junk people have to read because of your 'woe is me I have acne scars' posts? Have some perspective dude. It's laughable how you think acne scars are such a big deal. Take care of your emotional problems elsewhere and let's try to have a substantial discussion on the facts.

12 minutes ago, RickeyDog1989 said:

@surgical scarJudging by your post history, you don't think you're the most frequent contributor to starting fights and throwing tantrums? Asking posters who continue to post off-topic questions since months back, and explaining the reasons why others would appreciate their stopping derailing the thread is 'gibberish'? Ironic coming from you. Do you understand how many pages people have to skip because of your 'woe is me I have acne scars' posts? Have some perspective dude. It's laughable how you think acne scars are such a big deal.

If you had read any of my posts you'd know I don't feed the trolls, so you'll get your answer when @Control Panelcomes and meanwhile find someone else for attention

Also, if you had read any of my posts you'd know I didn't say'woe is me I have acne scars', nor do I think acne scars are a big deal neither give a damn about acne scars, so check with an IQ doctor asap before digging your grave deeper...

i apologise my crime or mistake i never ask about acne again sorry..please continue your scarless heaing talk..i wont disturb anymore

11 hours ago, Ps93 said:

Interesting article about the antiscarring drug of birchbiomed: http://www.ceocfointerviews.com/interviews/BirchBioMed18.htm

Looks interesting going into phase II trials. They claim it can break down existing scar tissue and be injected. Really does sound lile a magic cream lol...

No hype like with PolarityTe. Cant seem to find photos or any evidence from pre-clinical trials?

Just when you think Sunogel has the best looking model these researchers claim this FS2 cream can break down scar tissue.

its all positive signs anyway with more and more competition to crack the wound care market which is only getting bigger and doesnt have any real decent solutions. After 2 decades of lasers being overhyped and offering minimal results it would be nice to see the next advancement make a real difference. Good luck to them and we will keep track of how results fair. Its a busy year for "Scarless healing" 2018. We just need Sunogel to up their game if they are genuine.

Sunogel-

Pros- people behind the product with impressive backgrounds. Finalists at hello tomorrow convention in Paris. And of course the pre-clinical results of flawless healing in swine models.

Cons- working from strip mall. Crappy website. Dr Sun not the most business savvy person in the industry taking so long to get even to trials let alone market.

Some nice before and afters. Picosure + Vivace radio frequency. Instead of waiting for scarless healing....

On 4/23/2018 at 11:33 PM, Ps93 said:

Interesting article about the antiscarring drug of birchbiomed: http://www.ceocfointerviews.com/interviews/BirchBioMed18.htm

Great find I didnt know they were already set with phase 2.

As much as I wish topicals would be the answer, I dont know if something such as their ointment would work; at least not by itself anyway.

I had researched a long time ago on why there were so many creams and products like snake oils that got popularized in the market and so I wondered why most of them turned up as frauds. So I investigated the scar creams specifically and wondered how they could even deliver from the surface down into the dermis where scars form. I had discovered Liposomes and how they carry the topical and penetrate down through the skin to get absorbed by the deeper layers.

Sadly I found that not too long ago studies were done on the effectiveness of drug absorption through Liposomes and discovered they had now verified that they cant break through into the skins layers.

https://www.sciencedaily.com/releases/2016/03/160307113316.htm

https://www.ncbi.nlm.nih.gov/m/pubmed/16597359/

The vesicles in the skin were observed to actually dissolve and diffuse the topical before it could ever begin penetrating the skin. On the bright side its unknown if the topical agents are eradicated once they are dissolved by the vesicles or if they undergo some form of absorption that get carried into the deeper tissue.

Topicals could also be transported into the deeper layers via the hair shafts (follicles), but its not very effective for absorption since the shaft takes up most of the space from the exiting pathway on the surface of your skin. Plus most scars usually dont have hair follicles so you could count this method of transport out.

My opinion is that there is an easy way for topical absorption despite what was mentioned above and its through simple microneedling. Theres a wide variety of studies that prove it is much more effective for topical absorption one of them actually being a hair growth study. Its also obvious that if you make many holes in your skin extending into the depths of the dermis that anything you put on will more than likely get absorbed into where the scar tissue resides.

I do still think its worth keeping an eye on this especially since theyve said it is reverting alopecia (hair loss type) since as most of us probably know by now that hair and skin are linked. Also stated that it can even treat Type I Diabetes.

http://birchbiomed.ca/wp-content/uploads/2018/02/02-05-18-Sensus-BirchBioMed-letterhead.pdf

Aside from them saying they have the means to prevent and eliminate scarring as stated in the link above, they are partnering with Sensus Healthcare to do it.

.

26 minutes ago, Tano1 said:

Great find I didnt know they were already set with phase 2.

As much as I wish topicals would be the answer, I dont know if something such as their ointment would work; at least not by itself anyway.

I had researched a long time ago on why there were so many creams and products like snake oils that got popularized in the market and so I wondered why most of them turned up as frauds. So I investigated the scar creams specifically and wondered how they could even deliver from the surface down into the dermis where scars form. I had discovered Liposomes and how they carry the topical and penetrate down through the skin to get absorbed by the deeper layers.

Sadly I found that not too long ago studies were done on the effectiveness of drug absorption through Liposomes and discovered they had now verified that they cant break through into the skins layers.

https://www.sciencedaily.com/releases/2016/03/160307113316.htm

https://www.ncbi.nlm.nih.gov/m/pubmed/16597359/

The vesicles in the skin were observed to actually dissolve and diffuse the topical before it could ever begin penetrating the skin. On the bright side its unknown if the topical agents are eradicated once they are dissolved by the vesicles or if they undergo some form of absorption that get carried into the deeper tissue.

Topicals could also be transported into the deeper layers via the hair shafts (follicles), but its not very effective for absorption since the shaft takes up most of the space from the exiting pathway on the surface of your skin. Plus most scars usually dont have hair follicles so you could count this method of transport out.

My opinion is that there is an easy way for topical absorption despite what was mentioned above and its through simple microneedling. Theres a wide variety of studies that prove it is much more effective for topical absorption one of them actually being a hair growth study. Its also obvious that if you make many holes in your skin extending into the depths of the dermis that anything you put on will more than likely get absorbed into where the scar tissue resides.

I do still think its worth keeping an eye on this especially since theyve said it is reverting alopecia (hair loss type) since as most of us probably know by now that hair and skin are linked. Also stated that it can even treat Type I Diabetes.

http://birchbiomed.ca/wp-content/uploads/2018/02/02-05-18-Sensus-BirchBioMed-letterhead.pdf

Aside from them saying they have the means to prevent and eliminate scarring as stated in the link above, they are partnering with Sensus Healthcare to do it.

Applying a topical or taking it orally to break down scar tissue under the skin seems dubious at best lol...surely topical and orally are in reference to a fresh wound unless as you say Microneedling is possible yes for this product if it were succesfull in upcoming trials in order to break down and remove scar tissue.

Does anyone know what animal models did they achieve this in in pre-clinical trials?...i thought i read online somewhere it was rabbits.

They state that it breaks down and removes scar tissue and doesnt hinder healing. So essentially its a another way of saying normal skin regeneration. Its another step in the right direction and hopefully we are on the cusp of something great.

Out of curiousity was anybodies acne scarring caused by taking accutane? I know the spots cause it as such but did your spots never scar before accutane?

I only took it for 7 days but the spots i had come up while on it have left little white blobs...hmm..

52 minutes ago, nikki_gargin said:

Out of curiousity was anybodies acne scarring caused by taking accutane? I know the spots cause it as such but did your spots never scar before accutane?

I only took it for 7 days but the spots i had come up while on it have left little white blobs...hmm..

I never took Accutane and those blobs you are referring too are called perifollocular elastolysis, popular acne scars or mid dermal elastolysis. I have hundreds of these on my jawline, buttocks, thighs, shoulders and sides of my back from years of severe acne. I must say I was diagnosed with acne conglobata but was put on antibiotics and saw a gradual improvement while I was a teenager.

I was the only kid amongst my friends, who had it bad. All had a few pimples on their faces but my pimples were angry, infected and covered large parts of my body. Most of my friends knew about my suffering but didn't talk about it. It didn't really hold me back however. I was handsome and scored many times. At the end it was all in my head.

I also used extensive chemicals on my skin to kill all kinds of bacteria. I'm almost reaching my forties and still breakout time to time on my back.

Unfortunately, I am left with white blobs that are slightly raised from all those boils. I don't believe Accutane, any of these topicals or antibiotics make your skin more prone to scarring.

Scarring depends on each individual. Some people scar easily while others don't. More severe acne means more inflammation which means more scarring. I had it pretty bad on my face but my scarring is barely noticeable. These blobs you speak of are there but are only noticeable to me. To others, they are too small to be noticed.

Anyways, these white blobs are a consequence of inflammation, your skin is stretched to its limit by the pimple. Once the pimple heals, your skin has lost its elastic fibers in the dermis and it leaves you with a wrinkled slightly raised white hypertrophic scar. Some of mine have flattened over time, others have disappeared completely. Many however remain. Think of them as miny stretchmarks. They are related to another skin condition known as anetoderma which is spontaneous and not caused by inflammation.

These white blob scars are fairly common but they are neglected by the medical community. As acne is becoming more prevalent and more people develop them, modern medicine has now limited documentation on it. There is no known treatment but some dermatologists are experimenting with lasers which seem to make them less noticeable.

I don't care about the scars to be honest. All I want is for my nightmare to end with these breakouts. A functional acne cure would be more than welcomed.

Regarding Birchmedical, phase 2 is still a long way before we see their product on the market. They have to go through 3 more stages which means failure is very high. Even if phase 2 is succesful, phase 3 and phase 4 are far away. It can take a few years, so for many people with scars, they have to wait a little longer. However, a topical cream is the way to go to improve or eliminate scarring. They look more promising than Sunogel or SkinTE. They are taking the traditional approach of conducting clinical trials but again we are lacking peer reviewed documentation as well.

12 hours ago, Acnesucksforgood said:

I never took Accutane and those blobs you are referring too are called perifollocular elastolysis, popular acne scars or mid dermal elastolysis. I have hundreds of these on my jawline, buttocks, thighs, shoulders and sides of my back from years of severe acne. I must say I was diagnosed with acne conglobata but was put on antibiotics and saw a gradual improvement while I was a teenager.

I was the only kid amongst my friends, who had it bad. All had a few pimples on their faces but my pimples were angry, infected and covered large parts of my body. Most of my friends knew about my suffering but didn't talk about it. It didn't really hold me back however. I was handsome and scored many times. At the end it was all in my head.

I also used extensive chemicals on my skin to kill all kinds of bacteria. I'm almost reaching my forties and still breakout time to time on my back.

Unfortunately, I am left with white blobs that are slightly raised from all those boils. I don't believe Accutane, any of these topicals or antibiotics make your skin more prone to scarring.

Scarring depends on each individual. Some people scar easily while others don't. More severe acne means more inflammation which means more scarring. I had it pretty bad on my face but my scarring is barely noticeable. These blobs you speak of are there but are only noticeable to me. To others, they are too small to be noticed.

Anyways, these white blobs are a consequence of inflammation, your skin is stretched to its limit by the pimple. Once the pimple heals, your skin has lost its elastic fibers in the dermis and it leaves you with a wrinkled slightly raised white hypertrophic scar. Some of mine have flattened over time, others have disappeared completely. Many however remain. Think of them as miny stretchmarks. They are related to another skin condition known as anetoderma which is spontaneous and not caused by inflammation.

These white blob scars are fairly common but they are neglected by the medical community. As acne is becoming more prevalent and more people develop them, modern medicine has now limited documentation on it. There is no known treatment but some dermatologists are experimenting with lasers which seem to make them less noticeable.

I don't care about the scars to be honest. All I want is for my nightmare to end with these breakouts. A functional acne cure would be more than welcomed.

Regarding Birchmedical, phase 2 is still a long way before we see their product on the market. They have to go through 3 more stages which means failure is very high. Even if phase 2 is succesful, phase 3 and phase 4 are far away. It can take a few years, so for many people with scars, they have to wait a little longer. However, a topical cream is the way to go to improve or eliminate scarring. They look more promising than Sunogel or SkinTE. They are taking the traditional approach of conducting clinical trials but again we are lacking peer reviewed documentation as well.

Yes Phase 2 could take anywhere from several months to 2 years unfortunately. Phase 3 involves alot more people (a few thousand) so if things go well in Phase 2 there will be many people scrambling to sign up because phase 3 could also take 1-4 years...

The success rate during phase 3 is 50% which will compare this anti scar drug against the 'gold standard' of care for scars which is I dont know what lol.....lets just say this FS2 cream doesnt have much competition to worry about with todays cosmetic trratments offering little if any improvement much of the time.

You can get the drug treatment in Phase 4 without enrolling in study. In Phase 4 you are helping researchers learn more about the treatment.
I emailed them about timelines and enrolling more so to see what they say.

I wouldn't recommend Accutane to my worst enemy

I just have one on my under my jawlin and today noticed one on my forehead. I dont mind them but thought it was odd because ive had HUGE under skin spots that have sat there for a month and never scarred. Im lucky. Thanks for the info very interesting x

On 23/04/2018 at 5:25 AM, Raster said:

As an aside, what do you guys think of bioprinting skin? This seems to be a big thing now in biotechnology, though nothing really concrete yet:

http://www.thehansindia.com/posts/index/Business/2018-03-25/This-startup-bioprints-3D-skin/369243
https://3dprint.com/162193/wfirm-3d-printed-skin-burn-care/
https://www.digitaltrends.com/cool-tech/inside-cellink-hq/

oh my...if they could reprint someones face imagine the joy for people in trauma or burns....wow i couldnt even imagine

how the hell that bioprinter is useful for wounds or scars..
that bioprinter print your skin than how can u apply it on a wound or scar