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I was curious about potential procedures using ACell. Someone mentioned a TCA peel with ACell applied as a healing agent. The most popular line of thought on here has been excision followed by ACell application. If this was the procedure, how would you prep the wound for healing? Remove the scar and you're left with a (sometimes large) open wound. Would we just leave the wound open and apply the acell powder and cover it with a bandage of type or stitch up the wound and apply Acell to the stitches?
I worry a bit about stitches since they can create scars as well and may be more difficult to cover / heal with ACell.
I saw some pics on the website on it being used on animals, looks impressive, but I have to wonder that without Acell how well animals are able to heal.
Some facts for you Naitch:
The scarring response in body tissues is similar.
All animals, mammals and reptiles have the same ECM, it creates what tissue it surrounds on animals, mammals and reptiles. Humans are mammals.
Quote from page 1 of A-Cell Therapy Offers Renewed Hope For Horses Incurring Tendon And Ligament Injuries
www.acell.com/news/TCOTHACellArticle.pdf
aoeThe mixture acts as a framework forthe horseas own circulating stem cells to populate
the site and become appropriate, functional
tissue as the area heals, rather
than scar tissue,a added Mitchell.
Our unwounded bodies are using ECM as we type to regererate every tissue you have when you type. ECM is a key player in regeneration. It is the conductor. It attracts stem cells to the site, it brings what it needs.
Quotes from page 2 of A-Cell Therapy Offers Renewed
Hope For Horses Incurring Tendon
And Ligament Injuries
www.acell.com/news/TCOTHACellArticle.pdf
But as researchers explored what directsthe bodyathe signals the body uses to talk to
itselfathey realized that the extra-cellular
matrix is actually a virtual information highway,
and an important one at that.
The body uses this matrix area to aoetalka to
itself. Otherwise, an injury wouldnat heal,
because the rest of the body wouldnat
know where it was. There are many substances
that exist in that matrix, including
growth factors.
aoeACell Inc. was able to create a product
based on this virtual information highway
that can be used for tissue healing anywhere
in the body,a said Williams. aoeTheir product is
derived from pig urinary bladder matrix.
They remove all the cellular material and are
left with the extra-cellular matrix. Bladder tissue
was chosen because thereas a high percentage
of extra-cellular matrix versus cellular
material.a
The word A-cell, in Latin, means not cell.
A is the Latin root for aoenota (such as in the
word asymmetricalanot symmetrical).
aoeBy using this matrix, youare putting
into the wound a amini-ecosystem.a Youare
not just putting in one growth factor [like
IGF], youare putting in all the growth
factors and the inhibitors as wellathe little
switches that turn things on and off,a said
Williams.
ECM is 'universal.' It regenerates every tissue on the body that scars.
No one knows if it works for any scars.
There really isn't any definitive info saying if it's been used with TCA, Fraxel, or ever.
hoursafter, ECM has been tested on human mammals: A lesser denatured ECM has had a 95% regeneration success rate on a tissue on the body that scars.
http://www.dhzb.de/international_services/...essedetail/290/
ECM regenerates all tissue.
Acell 95% to 99.9% regeneration...
I found an interesting website of the Middle East Technical University's Biomaterial and Tissue Engineering Research Centre, where you can see different ECM and/or so-called artifical skin products. At the bottom of the webpage you'll see interesting before and after photos of a man who had a large piece of his nasal skin excised. You can also see them posted below. A product called APLIGRAF was placed on the area of the excision to help ecourage healthy tissue regeneration. The result looks rather good.
Here's the link to the website: http://www.biomed.metu.edu.tr/courses/term...0skin_cinar.htm
I also found a company called Organogenesis that is developing a cosmetic product called REVITIX which is based on the same technology used in APLIGRAF. Take a look here: http://www.organogenesis.com/products/bioa...cs/revitix.html
As you can see, the regenerative medicine industry and its little brother, regenerative cosmetics, is growing rapidly. That's good news! 
PS: I have been very busy lately so I apologize if I haven't replied to some posts and private messages. If you're one of the people to whom I have not yet replied, please forgive me. I will do so soon.
More about APLIGRAF.
Another FDA approved brand that for some reason is out of my reach! It's not our savior but I guess more proof that we are "getting there".
http://www.organogenesis.com/news/media_co...akthroughs.html
There have been no official trials of ACell on humans for scarring. Thus there are no real results (good or bad) for the media to frenzy over.
I'll echo whoever put the sentiments out there regarding the lack of knowledge possessed by many, if not most, dermatologists regarding scarring. I was trying to find a doctor who performed dermabrasion locally, I probably have called about 15-20 dermatologists and about half of them have asked me what that is.
Anyone find any doctors who will perform this?
You have to be very careful with dermabrasion. Several people on this board have had horror stories to tell about how it has left them with waxy, poreless skin that is also several shades lighter. Plus, after you get dermabrasion, you can't go out in the sun. You lose your ability to tan from what I understand. You should look into maybe getting mechanical needling with a tattoo gun for your back, or just wait a little while longer for this ACell...I think you could then get a deep TCA Peel and then have these healing scaffolds applied...
No offense January, but isn't your logic a bit backwards? If I were to go ahead and do dermabrasion and create worse looking skin, then wouldn't acell still be able to come through and heal it? So if I wait it out and it does the same thing, all I've lost is money. If derm works, then i've saved money and time. the only bad scenario is derm not working and acell not working, in which case i lose it, but regardless i have to try.
No hoursafter, January's logic is spot on. Dermabrasion will not achieve the same results because it will not penetrate the scar tissue enough. It will remove the top layer of skin, but you will need to individually treat each scar for ACell to be truly effective. This will not be a sandblast and touch up procedure. You will need an invasive cutting or burning away of scar tissue like what excision or TCA will offer. Dermabrasion will not prove to be a timely or cost effective solution.
Hoursafter, I thought you were talking about simply going and getting dermabrasion. I didn't think about applying ACell afterwards...
My thinking was that it's going to be awhile before ACell is accepted by doctors as a standard treatment (although I hope we can get it via a prescription instead of having to have them apply it because it seems very simple and would be a crime for doctors to get rich off of this), so that if you go to one for dermabrasion right now, that's all you are going to get at this point.
I had a dermatologist try to push me into getting dermabrasion a few years ago and whenever I hear anyone mention it, alarm bells go off. I was just trying to warn you, that's all...Many people who have had dermabrasion for pitted scars have said that they've only gotten at most a 20-30% improvement and have had to get it done more than once. Research has shown that dermabrasion, as well as laser resurfacing, works best for SHALLOW scarring, as well as for blending in excision scars.
I am thinking that maybe the method that will be used in the future is going to be either cutting out the pitted scars, stitching them up, going over the excision scars a few weeks later with a laser, and then using ACell scaffold/bandages, OR TCA Cross and then ACell.
I am thinking that maybe the method that will be used in the future is going to be either cutting out the pitted scars, stitching them up, going over the excision scars a few weeks later with a laser, and then using ACell scaffold/bandages, OR TCA Cross and then ACell.
Why wouldn't you simply apply ACell after the excision? Why waste time with a laser? I mean of course assuming ACell is gonna work like we are all hoping it to, applying it right after the excision would aid that initial wound in healing back normal. So I don't see a reason for waiting a few weeks, using a laser, THEN using ACell..? 
I am thinking that maybe the method that will be used in the future is going to be either cutting out the pitted scars, stitching them up, going over the excision scars a few weeks later with a laser, and then using ACell scaffold/bandages, OR TCA Cross and then ACell.
Why wouldn't you simply apply ACell after the excision? Why waste time with a laser? I mean of course assuming ACell is gonna work like we are all hoping it to, applying it right after the excision would aid that initial wound in healing back normal. So I don't see a reason for waiting a few weeks, using a laser, THEN using ACell..?
I think it would be great to be able to use it right after cutting out the scar(s). Maybe it will be, I don't know...I'm just speculating here. I think that a small, linear scar would be easier to erase, that's all. But if ACell is truly able to regenerate the way that we all hope and the way that Mike Manning has said it will, as well as from what we have read about, then maybe it could just be applied directly to an open wound...
Wow! I haven't seen this thread hit second page in weeks it seems. I'm calling some local derms tomorrow to see if they'll hear my case and maybe try out my theories with ACell. I'll keep you all updated. I think everyone should try to do the same. Just schedule consultations and try to persuade a dermatologist or plastic surgeon into trying these new methods. Just talking to them won't hurt anything. Make sure you present it as a business proposition first though. You don't want to be paying for the consultation.
When will we hear something about ACell results? There have been rumors about doctors experimenting with it in locations around the country. The fact that we haven't heard anything back couple of weeks maybe discouraging or signals no one on this board is in touch with one of these doctors. If you're from one of the areas, Toronta, NC, CA, try to get info!
so do i ask the derm if i can use this stuff after getting fraxel done??i m intested in using it for needling also....i dunno...i honestly dont know if this stuff really works and may couse more harm then good ..i dont want to damage my face anymore..so please..someone be the ginnie pig and do this .
I think we have the option for many available testers. I would more than love to test it, but I have no idea how I can get a hold of it and how I should apply it. Everyone has a different idea about how to use it in conjunction with excision, peels, lasers. I'd try whatever.
I would also like to talk with a plastic surgeon about this but I don't know what to say.
Should he get directly in touch with ACell?
Can he just write out a prescription?
Maybe I could call the CVS or Walgreen's pharmacy and see if they know anything since it is now available to the public...
Hey, I remember people talking about that they had directly contacted and talked to that main guy over at ACell. (I can't think of the name off han, but I think it was Micheal or something with an M.) My apologies I just got off work and I am really tired and don't feel like tracking it down, but I am sure someone on this thread knows who I am talking about lol. Anyways, I think I remembered hearing mentions of direct phone conversations and emails. I was wonder how you went about establishing a direct contact, as I have tried the info email, and his email (which sends the response after you join the mailing list), and I have not received a response on either attempt. Any info would help guys, thanks.
Email doesn't cut it in the real world, pick up your phone.
Check this out:
http://www.clinicalcellculture.com/o
Some of the case studies look mighty fine. This sounds a lot like the stuff Pharrell Williams has gotten himself into.
Look at this one in particular:
Email doesn't cut it in the real world, pick up your phone.
Check this out:
http://www.clinicalcellculture.com/o
Some of the case studies look mighty fine. This sounds a lot like the stuff Pharrell Williams has gotten himself into.
Look at this one in particular: