Acne.org Products
11 minutes ago, Ps93 said:
this is just recell rebranded hundreds of acne patients have tried it now and it doesn't do SHIT. ZERO PERCENT IMPROVEMENT. Just check out all the testimonies on this very site.
8 hours ago, Sniffy said:Area or size? Like is face more expensive or the size of area being treated?Also you said earlier about wound bed possibly having to be down to Muscle/fascia for SkinTe to get all appendages. So if its possible to treat someone for hyper or hypopigmentation you still need a full thickness biopsy if just resurfacing top layers of skin?
Here's the exact quote about price:
What is the price of the product? How is it reimbursed?
"PolarityTE contracts with individual hospitals, outpatient surgical centers and clinics, ambulatory surgical centers, and provider offices. The price of the product may very based upon contract and size of the treatment area. There is also a processing fee for expediting product turnaround to the provider. Reimbursement information, can be obtained by contacting PolarityTE Customer service."
So it says area. I'm guessing the price difference in this case isn't the kit, but rather the processing. As in, an entire back would take longer to process the paste for than the face (i.e. there would be more of it). That's just a guess though.
In terms of the skin biopsy of healthy tissue, I've always maintained that it needs all three layers of the skin so this is not a surprise to me. In terms of treating the top two layers of skin, I'm just guessing, but I think it would come down to whether or not you wanted your appendages back. Sebaceous glands appear to reside in the dermis but hair follicles and sweat glands look like they're in the hypodermis (where the subcutaneous fat resides).
2 hours ago, AI3forever said:So close yet so far. SkinTE may very well be the answer to our scars yet we cant find a surgeon to use it on us.
Given the response another poster got, I don't think you'll be able to use it until the pilot clinical trial is completed.
I wrote this before, but while SkinTE is registered with the FDA it still faces post-market approval through a trial. Until that trial is completed (which should happen in the first half of this year) then I don't think there's a chance a surgeon would use it on anyone outside the clinical trial or that had suffered a major accident involved 3rd degree burns or major tissue loss. I actually think they legally might not be able to.
We know NOTHING until an actual paper is published with results showing before and after on actual human patients. Everything till then is just your imagination and TE's marketing. They say it will happen this year but who know could be a couple years. We don't know. So just sit and wait as usual.
21 minutes ago, Rez77 said:We know NOTHING until an actual paper is published with results showing before and after on actual human patients. Everything till then is just your imagination and TE's marketing. They say it will happen this year but who know could be a couple years. We don't know. So just sit and wait as usual.
While we don't know the efficacy, we do know some things.
First, this was part of a message a poster here received from C. Scott Hultman:
I am a medical monitor for the clinical studies, and I have reviewed some of the preliminary data, but the product is not yet approved by the FDA for human use.
Polarity TE expects clinical use in humans to begin possibly later this year, after their trials are concluded and analyzed.
To me that is pretty clear: PolarityTE is conducting a trial as part of their FDA post-market approval process. Until that happens, no one not a part of those trials will receive the product unless he or she is in major crisis and the provider is looking for an alternative (I'm thinking burns over a huge part of the body where it would be next to impossible to graft healthy skin).
Sink or swim, we will know the first half of the year if it works completely, provides improvement or fails. It's on the young boy's body and he's already well into the healing process.
Also Rez77, you're last post you claimed that you weren't going to come back until the results were published. Why have you returned this time?
From what i read when researchers get success in pig trials this nearly always leads to the same in human as our skin is very similar.
I would to point out skinte and recell are 2 very different products. Recell wont do shit to third degree. It needs a dermis for the basal cells to populate and work upwards from. Also scars arent all alike if we are talking about scar tissue. I have a skin graft and where the skin was taken is 'scared' but its not true scar tissue...i have all my hair there etc. The graft though.... it is horrible stiff dry piece of leather. Im getting my skin graft removed via tissue expansion to grow my skin using a balloon to then use as a flap to cover. This will be great but im following skinte for surgical scar revision maybe 2019 ill fly from uk! Lol
The acne scar folk...i think your only problem may be plastic surgeons willing to make a full thickness injury to get rid of epidermal scaring. I have one true acne scar and i know my dermis is still there so its not a scar i could see anyone taking out 3 layers of skin to replace but they might not need to! We will have to wait for market release.
Also for the people who dont believe think about it critically
Do you think a team of plastic surgeons would not have tested this on themselves somewhere small before ruining there careers and reputations? If it would have gone wrong they can graft or do primary closure on eachother! 1cm off...reclose it agsin with skinte. I know if i had them skills and thst much money to make i would make sure it works before buying 200 squarefoot facility lol
It will cost a bomb though for aestetic use. If kit is $7000 then your surgeon will charge his time and niche product. 10k upwards i reckon
Ps they are trialing on ulcers, chronic wounds and surgical scars with burns. So should approve alot of skin use but might only be full thickness wounds.
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1 hour ago, nikki_gargin said:From what i read when researchers get success in pig trials this nearly always leads to the same in human as our skin is very similar.
I would to point out skinte and recell are 2 very different products. Recell wont do shit to third degree. It needs a dermis for the basal cells to populate and work upwards from. Also scars arent all alike if we are talking about scar tissue. I have a skin graft and where the skin was taken is 'scared' but its not true scar tissue...i have all my hair there etc. The graft though.... it is horrible stiff dry piece of leather. Im getting my skin graft removed via tissue expansion to grow my skin using a balloon to then use as a flap to cover. This will be great but im following skinte for surgical scar revision maybe 2019 ill fly from uk! Lol
The acne scar folk...i think your only problem may be plastic surgeons willing to make a full thickness injury to get rid of epidermal scaring. I have one true acne scar and i know my dermis is still there so its not a scar i could see anyone taking out 3 layers of skin to replace but they might not need to! We will have to wait for market release.
Also for the people who dont believe think about it critically
Do you think a team of plastic surgeons would not have tested this on themselves somewhere small before ruining there careers and reputations? If it would have gone wrong they can graft or do primary closure on eachother! 1cm off...reclose it agsin with skinte. I know if i had them skills and thst much money to make i would make sure it works before buying 200 squarefoot facility lolIt will cost a bomb though for aestetic use. If kit is $7000 then your surgeon will charge his time and niche product. 10k upwards i reckon
Ps they are trialing on ulcers, chronic wounds and surgical scars with burns. So should approve alot of skin use but might only be full thickness wounds.
I've often wondered if the creators of products don't test on themselves prior to market. Of course, the mitigating factor that indicates they don't are the sheer volume of failures in this sphere. I do agree that PolarityTE's actions are very bold (the 200k sqft facility, the accelerated push to market etc.) but I'm not so sure they would have tested it on each other. I'm not saying it's not possibleI for one would definitely do this if I was creating a product like SkinTE and abandoning my cushy position at a prestigious hospitalbut for some reason I don't think a lot of researchers do that.
I will say that with Sunogel, Dr. Sun 100% used his product on himself and even posted a picture on their Facebook. The results weren't too convincing because it was a hand injury that while he claimed was all the way down to the bone, didn't really show a lot in terms of results. Plus, fingers tend to heal much better than other parts of the body. Still, a precedent is there for a researcher using his or herself as a guinea pig.
After reading their info about price on their app, I'm not sure what it will cost. I think Cantor's quote of $7,300 was probably just a baseline estimate going off competitor prices. On their app, as I posted, it says it will depend on their contracts with the specific hospital, center etc. and the area of treatment (I'm pretty sure this means the sheer volume of skin needed, not a particular area of the body being more than another).
Acne scars get excised all the time, so I don't actually think that would stop a person from finding a provider willing to do this. It would certainly whittle down a patient's options, but if it works, there's money to be made and someone out there would do it, imo. I do agree 100% that if a less invasive procedure is created by PolarityTE the amount of patients that want it and providers that would do it would skyrocket.
On 2/21/2018 at 9:51 AM, sousou_bella said:Hi everyone,
Just an update - Dr. Mundinger got back to me and said he would not recommend SkinTE for my scars at this time. He recommended scar revision and said he would be happy to perform it. It's pretty disheartening to have that type of response at this point, especially considering the fact that he would be willing to create a new scar on me without using SkinTE in conjunction with excising my old scar. I understand that SkinTE is a new product and he's probably being cautious but I would have felt better if he would have asked me to get back to him in 6 months or even a year. I have responded to him thanking him for taking the time to write me but that I would really like to know why he wouldn't recommend SkinTE for me at this point, especially considering the fact that he would be willing to perform a scar revision through excision. I'm trying to be as pushy as possible without annoying him too much. We'll see what happens. I'm still hopeful that I might find a doctor who would be willing to use it on me, I may just have to wait a while. I read in one of the articles that the names of the ten clinics using SkinTE across the US are not being made public which helps me understand why Polarity would not give me that information when I emailed them twice with different email accounts hoping to get that information. At this point, I have contacted all of the clinical advisors whose names I was able to find but none of them would be willing to use the product on me at this point. Please bare in mind that only a few of the clinical advisors that I contacted are actually currently using SkinTE so I've only technically been told no by 2 of them. I'm awaiting a response from Dr. Mundinger while trying to come up with a new strategy to somehow get treated with SkinTE. I'm pretty determined if you haven't noticed haha. All the best guys! As always, I will keep you updated
Sorry to hear this! Who were the that told you they could not use on you at this time? I have had no luck yet either. Precious is not getting back to me at all! It would have been great if this doc would have been willing to try it on one of your scars just to see what happens! But I suppose the kit is big or something? idk
People may think that excising the whole 3 layers of skin is invasive and no surgeons would do that, but what about say heart or lung transplants? Those kind of treatments are 10 times more invasive and are procedures that surgeons would do on a patient right now. Granted those people that require these transplants are probably on the brink of death bed and have no better choice.
You can get a surgeon to say excise a scar on a non-prominent spot like your legs and arms or back, somewhere you don't really care if all goes wrong, If SkinTE works on that particular scar then there's no reason it doesn't work on the face.
If there is $$ to be made, I think there will be surgeons willing to jump on board once human trial results are out. Just see some of the ridiculous surgeries that plastic surgeons do now, I have watched one on youtube where the person implants fake muscles (Silicone) into their bodies. It is all for aesthetic purposes and because that guy is just too lazy to work out for real muscles. So what more can you say for a real actual need like scarring on the face? Definitely someone would do it if its proven to work.
The share price for Polarity crashed 6%. I'd actually buy some shares as a speculative play, if I was based in the US. The fees are too high here for international stocks.
I'm confident Skin TE will be just as effective as fraxel, but the question is whether it can have an actual impact on acne scars, and a much better impact than say lasers. For example, if this product only ends up as being effective as Fraxel, then that doesn't really help too many people who have posted in this thread.
SkinTE is an incredibly different kind of technology/method than Fraxel... I don't even know how they could be comparable. And I'm not even talking about results -- just how far they are as technology from on another.For one, Fraxel wasn't made to primarily address burn wounds, nor was it meant to grow full thickness skin. At most, it's meant to ablate scars to make them softer, perhaps kickstart some collagen synthesis.
I'd sooner compare this to actual skin grafts than try to compare it with Fraxel or other kinds of lasers.
59 minutes ago, Raster said:SkinTE is an incredibly different kind of technology/method than Fraxel... I don't even know how they could be comparable. And I'm not even talking about results -- just how far they are as technology from on another.For one, Fraxel wasn't made to primarily address burn wounds, nor was it meant to grow full thickness skin. At most, it's meant to ablate scars to make them softer, perhaps kickstart some collagen synthesis.
I'd sooner compare this to actual skin grafts than try to compare it with Fraxel or other kinds of lasers.
I'm not comparing Skin Te to Fraxel in terms of how it works, I was doing a hypothetical based purely on results. It is clear you totally misunderstood my post.
I don't disagree with anything you posted above, except we don't know yet if Skin te will be less effective than fraxel, or more effective, or maybe even the same.
8 hours ago, golfpanther said:I've often wondered if the creators of products don't test on themselves prior to market. Of course, the mitigating factor that indicates they don't are the sheer volume of failures in this sphere. I do agree that PolarityTE's actions are very bold (the 200k sqft facility, the accelerated push to market etc.) but I'm not so sure they would have tested it on each other. I'm not saying it's not possibleI for one would definitely do this if I was creating a product like SkinTE and abandoning my cushy position at a prestigious hospitalbut for some reason I don't think a lot of researchers do that.
I will say that with Sunogel, Dr. Sun 100% used his product on himself and even posted a picture on their Facebook. The results weren't too convincing because it was a hand injury that while he claimed was all the way down to the bone, didn't really show a lot in terms of results. Plus, fingers tend to heal much better than other parts of the body. Still, a precedent is there for a researcher using his or herself as a guinea pig.
Yeah, well, if it yielded good results I don't doubt they would show tests on themselves. Look at this doctor with perfect skin doing excision just for his students lol -
5 hours ago, ScarRight said:I'm not comparing Skin Te to Fraxel in terms of how it works, I was doing a hypothetical based purely on results. It is clear you totally misunderstood my post.I don't disagree with anything you posted above, except we don't know yet if Skin te will be less effective than fraxel, or more effective, or maybe even the same.
Its a very difficult comparison if your just looking at results. Fraxel makes your skin red for 4 days and your scars will maybe soften in appearance if that. You still look in mirror and see same old scars staring back in the same old locations.
SkinTe, well if its excision or dermabrasion resurfacing followed by progressive skin regenreation you can guarantee those original scars will be gone for good but will your final results be for better or worse who knows at this stage.
Subcision, Injectables and needling with SkinTe is more of an unknown.
12 hours ago, ScarRight said:The share price for Polarity crashed 6%. I'd actually buy some shares as a speculative play, if I was based in the US. The fees are too high here for international stocks.
I'm confident Skin TE will be just as effective as fraxel, but the question is whether it can have an actual impact on acne scars, and a much better impact than say lasers. For example, if this product only ends up as being effective as Fraxel, then that doesn't really help too many people who have posted in this thread.
No one knows until the results come out. The two technologies aim to do entirely different thingsFraxel aims at % improvement while SkinTE aims to provide true regeneration of all layers of skin. As Sniffy said, it's guaranteed that the original scars will still be there in the case of Fraxel and that hey wouldn't be in the case of SkinTE. He or she is also right to point out that at this stage no one knows if that means a better outcome with SkinTE or not.
In terms of the stock price, it's very interesting that it's going down so much in light of the extremely positive projections it has recently received. A theory from another poster on this site (and one I agree with) is that investors are purposely trying to drive the stock price down in the hopes they can buy back in at a much lower cost than they did originally just before positive results are released. It's a win-win in this case for investorsif it works (i.e. substantial improvement over skin grafts or complete regeneration) and they find out just before or right around the time results are released, they can rush back to the stock with huge investment at a low price and drive it up for themselves. If it fails to provide improvement, they got out while still making a profit.
It's very telling to me that while the stock price as gone there are no new articles that are dubious about their chances.
Another quote from the Cantor analysis:
With the use of SkinTE, the company has demonstrated "previously unseen results" of "flawless healing" in animals and positive early evidence in humans, Piros indicated. One of the first users of the product on a human was a physician who excised a "badly scarred, sizable (200 square centimeter) wound from the chest of a 10-year-old burn victim" and treated it with SkinTE. A month later, about midway through the healing process, the medical provider "proclaimed that the treatment 'definitely works."
200s square centimeters is a huge area. Also, "definitely works" sounds good to me coming from Mundinger. What level of "work" is obviously still debatable.
17 hours ago, kim6288 said:On 2/21/2018 at 2:51 PM, sousou_bella said:Hi everyone,
Just an update - Dr. Mundinger got back to me and said he would not recommend SkinTE for my scars at this time. He recommended scar revision and said he would be happy to perform it. It's pretty disheartening to have that type of response at this point, especially considering the fact that he would be willing to create a new scar on me without using SkinTE in conjunction with excising my old scar. I understand that SkinTE is a new product and he's probably being cautious but I would have felt better if he would have asked me to get back to him in 6 months or even a year. I have responded to him thanking him for taking the time to write me but that I would really like to know why he wouldn't recommend SkinTE for me at this point, especially considering the fact that he would be willing to perform a scar revision through excision. I'm trying to be as pushy as possible without annoying him too much. We'll see what happens. I'm still hopeful that I might find a doctor who would be willing to use it on me, I may just have to wait a while. I read in one of the articles that the names of the ten clinics using SkinTE across the US are not being made public which helps me understand why Polarity would not give me that information when I emailed them twice with different email accounts hoping to get that information. At this point, I have contacted all of the clinical advisors whose names I was able to find but none of them would be willing to use the product on me at this point. Please bare in mind that only a few of the clinical advisors that I contacted are actually currently using SkinTE so I've only technically been told no by 2 of them. I'm awaiting a response from Dr. Mundinger while trying to come up with a new strategy to somehow get treated with SkinTE. I'm pretty determined if you haven't noticed haha. All the best guys! As always, I will keep you updated
Sorry to hear this! Who were the that told you they could not use on you at this time? I have had no luck yet either. Precious is not getting back to me at all! It would have been great if this doc would have been willing to try it on one of your scars just to see what happens! But I suppose the kit is big or something? idk
ermmm... i thought it was not available commercially yet anyways? So nobody would be in a position to offer it to you at this time? They cant say yes even if they thought they could use it on you because its not on sale for aestetic use. So i think he is offering you what he can at this moment in time.
Be patient lol xx
1 hour ago, nikki_gargin said:ermmm... i thought it was not available commercially yet anyways? So nobody would be in a position to offer it to you at this time? They cant say yes even if they thought they could use it on you because its not on sale for aestetic use. So i think he is offering you what he can at this moment in time.Be patient lol xx
Agreed. I feel bad for encouraging sousou and kim to push for treatment. I didn't know until the medical monitor, C. Scott Hultman, responded to a poster on here that it's in the post-market trail period.
No one is going to recommend it until if and when that trial is concluded and has positive results.
Quite simply, the wouldn't be allowed to offer it for commercial use, even if they thought it was a screaming success. There is a reason why finding doctors using Skin Te is so difficult to find and contact, because that's what they want.
Only specific people selected in the current human trial are allowed treatment. I'm not sure why people are surprised that a doctor wouldn't treat them yet, because legally they wouldn't be allowed. Confidential agreements would have been signed, so doctors will not give too much away.
Also i dont think acne scars are being used in the trial. Proberly because there is so many types to generalise to all acne scars. Just burns and sugical in the scar camp i think. There are risks on the disclaimer about its use though. Mainly infection and allergy. So i think even with burn scars there might be an issue with surgeons taking off healed skin graft with no clinical need...who knows.
On 2/22/2018 at 7:58 PM, golfpanther said:I've often wondered if the creators of products don't test on themselves prior to market. Of course, the mitigating factor that indicates they don't are the sheer volume of failures in this sphere. I do agree that PolarityTE's actions are very bold (the 200k sqft facility, the accelerated push to market etc.) but I'm not so sure they would have tested it on each other. I'm not saying it's not possibleI for one would definitely do this if I was creating a product like SkinTE and abandoning my cushy position at a prestigious hospitalbut for some reason I don't think a lot of researchers do that.I will say that with Sunogel, Dr. Sun 100% used his product on himself and even posted a picture on their Facebook. The results weren't too convincing because it was a hand injury that while he claimed was all the way down to the bone, didn't really show a lot in terms of results. Plus, fingers tend to heal much better than other parts of the body. Still, a precedent is there for a researcher using his or herself as a guinea pig.
Dr .Sun must have confidence with his gel!Hope Sunogel will make the gel available to us soon
After reading their info about price on their app, I'm not sure what it will cost. I think Cantor's quote of $7,300 was probably just a baseline estimate going off competitor prices. On their app, as I posted, it says it will depend on their contracts with the specific hospital, center etc. and the area of treatment (I'm pretty sure this means the sheer volume of skin needed, not a particular area of the body being more than another).
Acne scars get excised all the time, so I don't actually think that would stop a person from finding a provider willing to do this. It would certainly whittle down a patient's options, but if it works, there's money to be made and someone out there would do it, imo. I do agree 100% that if a less invasive procedure is created by PolarityTE the amount of patients that want it and providers that would do it would skyrocket.
On 2/23/2018 at 4:31 PM, golfpanther said:Agreed. I feel bad for encouraging sousou and kim to push for treatment. I didn't know until the medical monitor, C. Scott Hultman, responded to a poster on here that it's in the post-market trail period.No one is going to recommend it until if and when that trial is concluded and has positive results.
thanks I got nowhere with it. Are the docs not legally allowed to even discuss it? I just have a problem with them offering a traditional scar revision or laser when thats like a setback. It would be better to do nothing. It bothers me that they would offer something like that which could add more scar tissue potentially. And also how they say I would not recommend skinte for this problem. What why? If it can regenerate tissue it would be the treatment of choice for every kind of scar tissue! So what are we looking at here for when the docs can start using skin te?