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2 hours ago, ermete55 said:8 hours ago, Sniffy said:$7300 is for the kit regardless of how much skin is being treated I guess...A standard biopsy for SkinTe kit is 2cm and that is enough to cover an entire arm. That will likely fill the syringe from the kit I guess. So a kit should easily do an entire face and maybe some of back for people who have scars there also.With a kit how much skin can you treat at the maximum? It depends on the size of the biopsy? Thank you
From reports it seems that the 1cm biopsy can cover 10% of a person's bodyroughly an entire arm.
6 hours ago, Anish004 said:i want to know one thing..is it possible that theres blood coming from injury site and that will not scar ? i mean what is the minimum severity of injury to scar ?
I think the general rule of thumb is that any damage to the dermis (second layer of skin) will result in a scar. However, it also comes down to a person's individual healing capabilities and as Sniffy said, some minor puncture wounds heal without scarring.
9 hours ago, Sniffy said:I read about images in March from an investor claiming this on Stocktwits. Its a good source of Information Stocktwits for daily updates all things concerning PolarityTe. Also alot of speculation like here keep in mind.Im not sure what the gap is between Mice skin and Pig skin vs Pig skin and Human skin but even if SkinTe needs optimizing it can also be seen as a good thing just it could delay future full scale release thats all. However PolarityTe did say early stages of healing were yielding correlative outcomes to Pig pre clinical results.
The redness from Pig photos in mid stage healing could be scar tissue or could be just prolonged redness as they do mention "progressive healing" often. From memory this is from a fully excised deep wound down to the muscle so this an extreme case. Acne scars dont compare to such wounds or burns thus healing should be more favorable for less severe defects one would think.
Thanks for clarifying the source, Sniffy. Yes, a lot of speculation on there. ChessHere does seem to be in the know but it's impossible to tell for sure. He or she claims to have bought 8000 shares so there's no way they aren't a little biased. Still, March makes sense for the release of photos, especially if it's working or a substantial improvement over existing methods. If the pictures show that, it'll be just like ChessHere saysthe stock price will go bananas.
You're correct about the skin being excised down to the muscle on pigs. But from my understanding of the tech, that's how it works. You need a wound bed of that depth so the paste can regenerate full-thickness tissue. Speculating, I guess it could be possible to just excise to the depth of the scar tissue and apply the paste, but I'm not sure if you'd get appendages that way.
7 hours ago, Raster said:https://stocktwits.com/ChessHere/message/113284964This might be the post Sniffy is referring to.
Yep thats it. I read somewhere else also about them holding a conference in March but nobody is sure if they are using it to unveil SkinTe patient images or to release pre-clinical data from OsteoTe. Surely its one of the two.
2 hours ago, ermete55 said:that price is too high
Keep in mind, Cantor's is an estimate, not the definitive word on the kit price.
I do think it will probably be close to that given how much competitors like Epicell cost.
I don't think scar excision for most of the scars people have on this board will be $5,000. But if SkinTE works, anyone getting the procedure done is likely looking at at least $8-$10k for the entire procedure.
That's why derivatives will be imperative for PolarityTE to exploit the cosmetic market. Most people won't have that kind of money to spend on a completely elective and cosmetic procedure.
5 hours ago, Sniffy said:Yep thats it. I read somewhere else also about them holding a conference in March but nobody is sure if they are using it to unveil SkinTe patient images or to release pre-clinical data from OsteoTe. Surely its one of the two.
My guess would be it'll mostly be about OsteoTE preclinical data, but they might present something about the young body. Either way, I'm excited for these next couple of months.
Also, this is mostly just a rehash of other articles, but great for PolarityTE that a major tech site like Gizmodo is now covering them:
https://gizmodo.com/utah-startup-claims-it-is-regenerating-skin-with-stem-c-1823160465
I find it odd that people keep referencing a paper written in October. I get that it's good journalism to offer a rebuttal to the bold claims PolarityTE is making, but that paper was written in Octoberbefore it was on human patients and when there was far more room to be skeptical about whether or not they were legitimiate at all.
Any news from the folks on this board that have been contacting doctors?
https://www.paysa.com/blog/2018/02/20/5-cutting-edge-companies-leading-the-way-in-3d-organ-bioprinting/ Interesting news about bioprinting and Rokit which says is one year away of making human skin.
18 hours ago, ermete55 said:On 2/20/2018 at 0:38 PM, Sniffy said:$7300 is for the kit regardless of how much skin is being treated I guess...A standard biopsy for SkinTe kit is 2cm and that is enough to cover an entire arm. That will likely fill the syringe from the kit I guess. So a kit should easily do an entire face and maybe some of back for people who have scars there also.With a kit how much skin can you treat at the maximum? It depends on the size of the biopsy? Thank you
For a SkinTe kit I guess maximum is the equivalent to an entire arm. But for a Burns victim in hospital with 60% burns to body Im sure Doctors would take extra biopsy's and request additional SkinTe kits to get it on patients skin covering every burn within that 48 hour window without hesitation. For acne scar and other small scars you would treat everything you can with a single kit which should be suffice.
I don't think the SkinTe paste can be stored for futue use? Anyone?
7 hours ago, ScarRight said:Hopefully they can make smaller kits for the cosmetic market, as the current kit that has been raised is for burn patients, and they would need more to cover a larger surface area.
Good point
Hi everyone,
Just an update - Dr. Mundinger got back to me and said he would not recommend SkinTE for my scars at this time. He recommended scar revision and said he would be happy to perform it. It's pretty disheartening to have that type of response at this point, especially considering the fact that he would be willing to create a new scar on me without using SkinTE in conjunction with excising my old scar. I understand that SkinTE is a new product and he's probably being cautious but I would have felt better if he would have asked me to get back to him in 6 months or even a year. I have responded to him thanking him for taking the time to write me but that I would really like to know why he wouldn't recommend SkinTE for me at this point, especially considering the fact that he would be willing to perform a scar revision through excision. I'm trying to be as pushy as possible without annoying him too much. We'll see what happens. I'm still hopeful that I might find a doctor who would be willing to use it on me, I may just have to wait a while. I read in one of the articles that the names of the ten clinics using SkinTE across the US are not being made public which helps me understand why Polarity would not give me that information when I emailed them twice with different email accounts hoping to get that information. At this point, I have contacted all of the clinical advisors whose names I was able to find but none of them would be willing to use the product on me at this point. Please bare in mind that only a few of the clinical advisors that I contacted are actually currently using SkinTE so I've only technically been told no by 2 of them. I'm awaiting a response from Dr. Mundinger while trying to come up with a new strategy to somehow get treated with SkinTE. I'm pretty determined if you haven't noticed haha. All the best guys! As always, I will keep you updated 
32 minutes ago, sousou_bella said:Hi everyone,
Just an update - Dr. Mundinger got back to me and said he would not recommend SkinTE for my scars at this time. He recommended scar revision and said he would be happy to perform it. It's pretty disheartening to have that type of response at this point, especially considering the fact that he would be willing to create a new scar on me without using SkinTE in conjunction with excising my old scar. I understand that SkinTE is a new product and he's probably being cautious but I would have felt better if he would have asked me to get back to him in 6 months or even a year. I have responded to him thanking him for taking the time to write me but that I would really like to know why he wouldn't recommend SkinTE for me at this point, especially considering the fact that he would be willing to perform a scar revision through excision. I'm trying to be as pushy as possible without annoying him too much. We'll see what happens. I'm still hopeful that I might find a doctor who would be willing to use it on me, I may just have to wait a while. I read in one of the articles that the names of the ten clinics using SkinTE across the US are not being made public which helps me understand why Polarity would not give me that information when I emailed them twice with different email accounts hoping to get that information. At this point, I have contacted all of the clinical advisors whose names I was able to find but none of them would be willing to use the product on me at this point. Please bare in mind that only a few of the clinical advisors that I contacted are actually currently using SkinTE so I've only technically been told no by 2 of them. I'm awaiting a response from Dr. Mundinger while trying to come up with a new strategy to somehow get treated with SkinTE. I'm pretty determined if you haven't noticed haha. All the best guys! As always, I will keep you updated.
They are using it for burns and other large wounds during this trial phase, thats what PolarityTe have instructed at this stage. You're only going to keep running into the same wall and get more frustrated.
We all understand your desperation but you have to come to the realisation they simply will not use it for your small scar atm. Its not available for people like you now. Id say the number of people who have had SkinTe are far less than what we all think.
You're getting this idea in your head that SkinTe wont help you because of these Doctors telling you no. Have you ever noticed the wording in each response that they cant Reccomend SkinTe "at this time". Thats Because they cant Reccomend SkinTe at this time lol...
1 hour ago, Sniffy said:They are using it for burns and other large wounds during this trial phase, thats what PolarityTe have instructed at this stage. You're only going to keep running into the same wall and get more frustrated.
We all understand your desperation but you have to come to the realisation they simply will not use it for your small scar atm. Its not available for people like you now. Id say the number of people who have had SkinTe are far less than what we all think.
You're getting this idea in your head that SkinTe wont help you because of these Doctors telling you no. Have you ever noticed the wording in each response that they cant Reccomend SkinTe "at this time". Thats Because they cant Reccomend SkinTe at this time lol...
I never said it wouldn't help me. I think it will help me which is why I'm being persistent. You don't have to agree with my methods. My persistence has benefited me greatly over the years. I'm just sharing my experience. I can go back to being a lurker without contributing like I was happily doing for many years. I can just direct message the couple of people who have asked me for updates. Just thought it was time to give back which is why I'm posting on this thread but I will stop if I get too much negativity or insistence from anyone that I stop pursuing SkinTE treatment. Thanks
1 hour ago, sousou_bella said:I never said it wouldn't help me. I think it will help me which is why I'm being persistent. You don't have to agree with my methods. I'm just sharing my experience. I can go back to being a lurker without contributing like I was happily doing for many years. Just thought it was time to give back but I will stop if I get too much negativity. Thanks
Oh no, don't disappear! I don't think Sniffy was being negative, just giving his or her opinion.
In terms of Mundinger's response, I think it's important for all of us to remember that SkinTE is going through a post-market clinical trial. That's how the 361 regulatory arm of the FDA worksyou can come to market without trials, but you face post-market approval.
Until the results are final there is no way Dr. Mundinger or any other doctor could possibly recommend the product to just anyone. For two reasons: 1) they still don't know the final outcome (efficacy) of the product and that will need to be published in peer-reviewed journals and 2) they can't guarantee its safety at this point either.
In all likelihood, even if Dr. Mundinger wanted to treat you with SkinTE, I don't think he'd be able to legally. Whoever has had the treatment to this point was part of the initial trial to prove safety and efficacy. Until that happens, no one else is getting the treatment.
Sorry for the frustration that this has caused you. And I certainly commend your tenacity and effort. I just think that at this time, unless one of us had major burn scars, no one on this board is getting to use it until results are published. :-/
Just now, golfpanther said:Oh no, don't disappear! I don't think Sniffy was being negative, just giving his or her opinion.In terms of Mundinger's response, I think it's important for all of us to remember that SkinTE is going through a post-market clinical trial. That's how the 361 regulatory arm of the FDA works”you can come to market without trials, but you face post-market approval.
Until the results are final there is no way Dr. Mundinger or any other doctor could possibly recommend the product to just anyone. For two reasons: 1) they still don't know the final outcome (efficacy) of the product and that will need to be published in peer-reviewed journals and 2) they can't guarantee it's safety at this point either.
In all likelihood, even if Dr. Mundinger wanted to treat you with SkinTE, I don't think he'd be able to legally. Whoever has had the treatment to this point was part of the initial trial to prove safety and efficacy. Until that happens, no one else is getting the treatment.
Sorry for the frustration that this has caused you. And I certainly commend your tenacity and effort. I just think that at this time, unless one of us had major burn scars, no one on this board is getting to use it until results are published. :-/
Makes perfect sense. Thank you
Cantor doubled down on their buy rating on PolarityTE's stock:
Key quote:The analysts wrote, We believe the recent weakness in the shares reflect a misunderstanding of the companys technology, associated with an erroneous publication regarding the company, the SkinTE product and the regulatory requirements for registration.
My guess is that he erroneous publication is either the White Diamond Research paper written in October or the Seeing Alpha article from December. Both are outdated at this point with the moves PolarityTE has made, but the effect of stuff like that can obviously last beyond the validity of anything that was written.
1 hour ago, sousou_bella said:I never said it wouldn't help me. I think it will help me which is why I'm being persistent. You don't have to agree with my methods. My persistence has benefited me greatly over the years. I'm just sharing my experience. I can go back to being a lurker without contributing like I was happily doing for many years. I can just direct message the couple of people who have asked me for updates. Just thought it was time to give back which is why I'm posting on this thread but I will stop if I get too much negativity or insistence from anyone that I stop pursuing SkinTE treatment. Thanks
Sorry if came across negative not my intention, just I feel your frustration and Im trying to explain why you keep getting same answers from these Doctors. Maybe they should have gone into more detail to explain to you why they keep saying no, yes I agree. Im frustrated seeing you frustrated thats all lol
Golfpanther explained the finer details that I sould have maybe gone into more detail in my post, theres a bunch of reasons why you cant get SkinTe now.
Keep digging you might not get treatment soon but maybe some more detail from them as to why, just ask him again why he says not at this time and hopefully he takes the time to email you back. Everybody is frustrated to a degree and waiting. Cheers
1 hour ago, Sniffy said:Sorry if came across negative not my intention, just I feel your frustration and Im trying to explain why you keep getting same answers from these Doctors. Maybe they should have gone into more detail to explain to you why they keep saying no, yes I agree. Im frustrated seeing you frustrated thats all lolGolfpanther explained the finer details that I sould have maybe gone into more detail in my post, theres a bunch of reasons why you cant get SkinTe now.
Keep digging you might not get treatment soon but maybe some more detail from them as to why, just ask him again why he says not at this time and hopefully he takes the time to email you back. Everybody is frustrated to a degree and waiting. Cheers
no worries hun ..Thanks! I appreciate it
This may have been there before, but I searched on my iPhone for PolarityTE and now the first result is for their real time assistant app.
I certainly have never seen that pop up before but I can't seem to find a version history to see when it was released. Still, this to me is great news. They've talked about it before (and maybe it was out prior but not showing up in Google searches?) but this is the first time I've seen it.
19 minutes ago, golfpanther said:This may have been there before, but I searched on my iPhone for PolarityTE and now the first result is for their real time assistant app.
I certainly have never seen that pop up before but I can't seem to find a version history to see when it was released. Still, this to me is great news. They've talked about it before (and maybe it was out prior but not showing up in Google searches?) but this is the first time I've seen it.
Did you download it?
For those asking earlier about how much skin can be treated and also about storing the biopsy or paste. This is from PolarityTe below
"Constructs are being developed to accommodate different sizes, and should be able to cover the entire body if needed. Our manufacturing process is also being developed to allow for cryopreservation to meet future patient needs."
The cryopreservation development would be ideal for Soldiers fighting in combat in foreign countries.
So, I read through the instructions of use section and it's a lot of stuff we know. Here's a pic from it:
The other interesting tidbit was in their FAQ about price. It said that PolarityTE has contracts with individual centers and the price will depend on those contracts AND the area being treated.
Just now, Sniffy said:Yes they did say it was for physicians so you probably wont get access
Oh, I got access. See above. I wouldn't be able to order any of it obviously. I think the real time assistant is actually mostly for helping you along after the product has been purchased.
22 minutes ago, golfpanther said:So, I read through the instructions of use section and it's a lot of stuff we know. Here's a pic from it:
The other interesting tidbit was in their FAQ about price. It said that PolarityTE has contracts with individual centers and the price will depend on those contracts AND the area being treated.
Area or size? Like is face more expensive or the size of area being treated?
Also you said earlier about wound bed possibly having to be down to Muscle/fascia for SkinTe to get all appendages. So if its possible to treat someone for hyper or hypopigmentation you still need a full thickness biopsy if just resurfacing top layers of skin?