Acne.org Products
Correct me if I'm wrong, but the information is included in the 10-K SEC report (which is required of them), not because of the stock prices. Please read the actual post.
Yeah, it's an annual report that they are required to submit to the SEC. It's just a nice boon to hear that the results are correlative to what they got in pigs.
The wording isn't the clearest, but until they get the final results there's no way they should make any definitive statements.
they haven't released it. they don't even have it yet. their claims are based on "preclinical testing" which means *(&(& all. Where's the published peer reviewed paper with epidemological and in vivo results? With pics??? Nope its just like epibone check out epibone, it's nothing, just an idea, they're entrepreneurs.
9 minutes ago, Rez77 said:they haven't released it. they don't even have it yet. their claims are based on "preclinical testing" which means *(&(& all. Where's the published peer reviewed paper with epidemological and in vivo results? With pics??? Nope its just like epibone check out epibone, it's nothing, just an idea, they're entrepreneurs.
So Rez77 you are saying that its not even on patients and this statement release is a complete lie from PolarityTe?
On 1/28/2018 at 4:40 PM, Tano1 said:I dont think the real tragedy is their mental state, but more so their impulsive influences and lack of knowledge that leads to their mental state of hopelessness and depressive behavior.
I havent even looked at this thread in months, but I can probably guess that:
1.) People are still complaining and comparing products that they have very basic knowledge of, but yet still want to get spoon fed these very same updates that in reality keep them clinging on to this thread.
2.) Some who repeatedly feel the need to remind the thread every other day about their sob story of their battle with scars for sympathetic responses that probably benefits no one.
3.) People who ride the emotional roller coaster by reacting on impulse and changing their entire views, beliefs, ethics and mental state with each passing post about something they probably havent even bothered to research.
Be honest, how many do you think would trade all of the above for just some useful and factual information that they can verify. If anything, the reason people are still here is because there are still the few who are going the extra mile by investigating and providing information to the thread that is clearly visible from this last thread page.
Tano hit the nail on the head regarding some people here. Not to mention elements of paranoia not unlike conspiracy theorists.
Fortunately, most are level headed enough to look at things objectively.
1 hour ago, Sniffy said:1 hour ago, Rez77 said:they haven't released it. they don't even have it yet. their claims are based on "preclinical testing" which means *(&(& all. Where's the published peer reviewed paper with epidemological and in vivo results? With pics??? Nope its just like epibone check out epibone, it's nothing, just an idea, they're entrepreneurs.
So Rez77 you are saying that its not even on patients and this statement release is a complete lie from PolarityTe?
Honestly, I was going to respond directly to Rez77, but at this point ignoring him or her is for the best. No amount of logic will work for whatever reason. It's fine to doubt if the product will give us complete regeneration, but speculating about the doctors being part of some elaborate lie/conspiracy is pointless.
16 minutes ago, golfpanther said:Honestly, I was going to respond directly to Rez77, but at this point ignoring him or her is for the best. No amount of logic will work for whatever reason. It's fine to doubt if the product will give us complete regeneration, but speculating about the doctors being part of some elaborate lie/conspiracy is pointless.
Yes Rez77 seems very hostile and slightly unstable sadly. Has some sort of deep hatred for these biotech companies based on some previous let downs perhaps.
He/she needs professional help. Coming here posting uninformed garbage does him/her no good. The fact that Rez77 calls these Doctors Liars and Scammers for money is astonoshing despite the fact they are renowned Doctors with reputations on the line and are trying to solve a difficult problem and help the very people they treat. Rez77 feels as if they are offering false hope to something that bothers Rez77 deeply in acne scars as though they are cheating him/her and rubbing his/her face in it even more.
The first sign of something positive about SkinTe and Rez77 is on here faster then Speedy Gonzalez to try douse any hope and encouragement people may feel. Pathetic really. Rez77 is the defintion of troll if ever Ive seen.
new updates from SkinTe on their Fb page and here
https://ir.polarityte.com/all-sec-filings/content/0001493152-18-001228/form10-k.htm?TB_iframe=true&height=auto&width=auto&preload=false
11 minutes ago, Anish004 said:new updates from SkinTe on their Fb page and here
https://ir.polarityte.com/all-sec-filings/content/0001493152-18-001228/form10-k.htm?TB_iframe=true&height=auto&width=auto&preload=false
They mention scar revision in there, but not specifically acne scars.
And they're claiming human trials at the early stages are on par with the pre clinical trials?
14 minutes ago, ScarRight said:They mention scar revision in there, but not specifically acne scars.And they're claiming human trials at the early stages are on par with the pre clinical trials?
scar revision mean treatment of every scar.....
is it neccesary to put every name of scars like ice pick,boxcar,Rolling,chickenpox scar,Blade scar,Accident scar ???
scar menas scar...
37 minutes ago, Anish004 said:scar revision mean treatment of every scar.....
is it neccesary to put every name of scars like ice pick,boxcar,Rolling,chickenpox scar,Blade scar,Accident scar ???
scar menas scar...
If that is the case, that is very significant, because in the past they have mentioned mostly burn wounds and bigger scars. They actually do mention the word ' cosmetic' in that document too, which I also find very significant.
You would think the cosmetic market would be massive and where the real big bucks lie.
This is probably the most relevant line for the people interested here:
Complete the full commercial launch of SkinTE and establish SkinTE as an improvement over the standard of care for skin tissue injuries, including wounds, burns and scars.
We believe that SkinTE has the potential to supplant prevailing methods of wound and burn care because, unlike existing treatment options, it is designed to regenerate full-thickness skin using small samples of the patients own tissue. Rather than being limited by dimensions of the tissue received, SkinTE is designed to regenerate significantly beyond the sample size. Our initial limited commercial roll-out of SkinTE commenced in November 2017 and has focused on severe wounds and burn patients at key regional centers as, in our experience, these patients are often in critical need of large areas of skin regrowth and may have limited available healthy skin to use for skin grafts. However, we expect to make SkinTE commercially available to address the broader wound market, which is expected to exceed 250 million wounds worldwide by 2020. Along with the treatment of acute and chronic wounds, we intend to market SkinTE for other surgical reconstruction events, including cosmetic and elective surgeries, and for scar revision or the removal of dysfunctional events. We are leveraging the front-line experience of our leadership team to enhance adoption of SkinTE by physicians and patients by designing our products with a focus on simplicity, the user experience, reliability and ease of application. For SkinTE, and for each of our product candidates we plan to commercialize, we intend to conduct prospective clinical evaluations to compare the products to the standard of care, to bolster adoption and reimbursement with third-party payers.
On 1/28/2018 at 3:48 AM, Sniffy said:SkinTe is maybe 7 weeks into human trials so no Doctor is going to cut into your face to use it atm, nobody knows the results so how could they possibly recommend SkinTe to you. But they will take your money for other treatments no worries in the mean time. Fat Grafting is a good option btw if you cant wait.I understand your desperation but you cant honestly think they were going to say yes come in next week and we will do this for you. Its seems mostly being used for burns atm also. I think the only scar revisions being treated look like healed skin grafts for now.
Even if it did work well and got 80-90% they would still want to see a large sample size of various defects/wounds to prove its consistency before they started treating acne scar victims with whatever method they see fit. Its too early and too risky to be ringing around surgeons asking if they can slice your face up and use a product that may not give you what you want. I wouldnt consider this until you know for sure and seen photos.
They could always start on people who had acne scars on their back.......and if it fails or messes up the scarred area worse...who cares..it is only your back.
40 minutes ago, Raster said:This is probably the most relevant line for the people interested here:
Complete the full commercial launch of SkinTE and establish SkinTE as an improvement over the standard of care for skin tissue injuries, including wounds, burns and scars.
We believe that SkinTE has the potential to supplant prevailing methods of wound and burn care because, unlike existing treatment options, it is designed to regenerate full-thickness skin using small samples of the patients own tissue. Rather than being limited by dimensions of the tissue received, SkinTE is designed to regenerate significantly beyond the sample size. Our initial limited commercial roll-out of SkinTE commenced in November 2017 and has focused on severe wounds and burn patients at key regional centers as, in our experience, these patients are often in critical need of large areas of skin regrowth and may have limited available healthy skin to use for skin grafts. However, we expect to make SkinTE commercially available to address the broader wound market, which is expected to exceed 250 million wounds worldwide by 2020. Along with the treatment of acute and chronic wounds, we intend to market SkinTE for other surgical reconstruction events, including cosmetic and elective surgeries, and for scar revision or the removal of dysfunctional events. We are leveraging the front-line experience of our leadership team to enhance adoption of SkinTE by physicians and patients by designing our products with a focus on simplicity, the user experience, reliability and ease of application. For SkinTE, and for each of our product candidates we plan to commercialize, we intend to conduct prospective clinical evaluations to compare the products to the standard of care, to bolster adoption and reimbursement with third-party payers.
This was also another interesting line regarding the cosmetic appearance of the regenerated skin. Texture & Colour very important in terms of overall result.
"we believe a patients own tissue can be regenerated, along with its natural coloring and texture, layers and structure, hair and appendages"
We believe SkinTE has the potential to supplant prevailing methods, ..establish SkinTE as an improvement over the standard of care for skin tissue injuries...why not SkinTE has the potential to make any other skin treatment completely obsolete. Zzz.. from their wording it sounds like they are looking for a few percent improvement over skin grafts in burn wounds and ease of applicationlike BeautifulAmbition argued in some other thread. Doesnt read like a revolutionary product at all from their wording:/
Supplant = supersede, replace, make obsolete.
Automobiles supplanted horses as the primary means of ground transport.
Telephones supplanted the telegram.
I don't understand what you're saying...
On 1/31/2018 at 9:46 AM, nikkigirl said:They could always start on people who had acne scars on their back.......and if it fails or messes up the scarred area worse...who cares..it is only your back.
Hard to say what approach is taken with Acne scars if all continues going well and final results are good. I just dont think Excision will be totally necessary, seems like overkill. Remembering also they are developing derivatives for applying SkinTe ahead of moving into the cosmetic market but im scratching my head as to what that may be. The goal for PolarityTe entering the cosmetic market would be to allow for easy use of SkinTe for Doctors and dermatologist to treat acne scars and other smaller defects in clinics as opposed to choking up the hospital system. They have the Real time assistance app already for practioners.
Knowing SkinTe showed evidence of proliferation/expansion into scar tissue you would hope less invasive methods like subcision with needling followed by injecting SkinTe would be suffice for rolling acne scars that are affected because of underlying scar tissue contraction with otherwise normal overlying surface skin. Giving sufferers there smooth contour back as SkinTe heals without contraction and eliminating long recovery and other risks associated with excision. Also taking into account that acne scars are usually surrounded by normal skin unlike burns or other large such wounds that will cover 100% of the affected area hence why it doesn't seem appropriate to remove the entire area if it can be avoided.
Surface Texture/color issues caused from anything from ice pick scars, large pores to hyperpigmention would maybe be considered with dermabrasion with needling then applying SkinTe over skin.
It would be great to see the end of the Laser era.
Its all a guessing game this early though.