Acne.org Products
1 hour ago, kim6288 said:uh-oh. and one of the docs on the list of skin te I called his assistant told me the doc wants to talk to me about other options like laser and fat injections. He is one of the ones on the list of docs currently using skinte. He is supposed to call me should be interesting what he says about skin te. If this could regenerate skin wouldn't they use this on any type of scar. How depressing!
He wants to use laser and fat injections instead of skin TE for your scars? Hopefully that is because Skin TE is only supposed to be used on the trial patients at this current stage. Very interesting and please report back here on what he says.
2 hours ago, kim6288 said:uh-oh. and one of the docs on the list of skin te I called his assistant told me the doc wants to talk to me about other options like laser and fat injections. He is one of the ones on the list of docs currently using skinte. He is supposed to call me should be interesting what he says about skin te. If this could regenerate skin wouldn't they use this on any type of scar. How depressing!
Great job getting this far.Just to be clear... did the assistant say the doc is actually even using SkinTE? To clarify, the list I provided on the board is merely the names of the clinical advisors to SkinTE. I have no idea if they are actually the ones using it. The list was only meant to provide people on this board with a jumping off point if they wanted to start trying to find who was using it.
If he is using it and is recommending laser and fat injections that could be bad news or it could be that like PolarityTE has saidthe process is incredibly invasive and it would be up to the patient and provider to decide if it was worth it for the patient's indications. Given that even if he has used it on burn patients the results are not likely final, it would be risky to start using it on anything outside the main use of the product.
Please let us know as soon as you can once you've talked to him and find out what he says. I'm not sure he'll actually discuss SkinTE results with you if he has any(he might have signed a non-disclosure agreement with PolarityTE so they can control the flow of information) but definitely ask.
Out of curiosity, which doctor is it?
On 1/27/2018 at 10:51 PM, golfpanther said:the process is incredibly invasive and it would be up to the patient and provider to decide if it was worth it for the patient's indications. Given that even if he has used it on burn patients the results are not likely final, it would be risky to start using it on anything outside the main use of the product.
What is incredibly invasive?
10 hours ago, CoconutRough said:Laughable? Why so huffy?
Don't you see that alot of ppl who post in this thread rather need psychological help than believing in a technology that's not going to happen?Ppl are so lost that they can't even stop posting here. That's the real tragedy.
after insulting each other..
I dont think the real tragedy is their mental state, but more so their impulsive influences and lack of knowledge that leads to their mental state of hopelessness and depressive behavior.
I havent even looked at this thread in months, but I can probably guess that:
1.) People are still complaining and comparing products that they have very basic knowledge of, but yet still want to get spoon fed these very same updates that in reality keep them clinging on to this thread.
2.) Some who repeatedly feel the need to remind the thread every other day about their sob story of their battle with scars for sympathetic responses that probably benefits no one.
3.) People who ride the emotional roller coaster by reacting on impulse and changing their entire views, beliefs, ethics and mental state with each passing post about something they probably havent even bothered to research.
Be honest, how many do you think would trade all of the above for just some useful and factual information that they can verify. If anything, the reason people are still here is because there are still the few who are going the extra mile by investigating and providing information to the thread that is clearly visible from this last thread page.
7 hours ago, kim6288 said:uh-oh. and one of the docs on the list of skin te I called his assistant told me the doc wants to talk to me about other options like laser and fat injections. He is one of the ones on the list of docs currently using skinte. He is supposed to call me should be interesting what he says about skin te. If this could regenerate skin wouldn't they use this on any type of scar. How depressing!
SkinTe is maybe 7 weeks into human trials so no Doctor is going to cut into your face to use it atm, nobody knows the results so how could they possibly recommend SkinTe to you. But they will take your money for other treatments no worries in the mean time. Fat Grafting is a good option btw if you cant wait.
I understand your desperation but you cant honestly think they were going to say yes come in next week and we will do this for you. Its seems mostly being used for burns atm also. I think the only scar revisions being treated look like healed skin grafts for now.
Even if it did work well and got 80-90% they would still want to see a large sample size of various defects/wounds to prove its consistency before they started treating acne scar victims with whatever method they see fit. Its too early and too risky to be ringing around surgeons asking if they can slice your face up and use a product that may not give you what you want. I wouldnt consider this until you know for sure and seen photos.
7 hours ago, Sniffy said:SkinTe is maybe 7 weeks into human trials so no Doctor is going to cut into your face to use it atm, nobody knows the results so how could they possibly recommend SkinTe to you. But they will take your money for other treatments no worries in the mean time. Fat Grafting is a good option btw if you cant wait.I understand your desperation but you cant honestly think they were going to say yes come in next week and we will do this for you. Its seems mostly being used for burns atm also. I think the only scar revisions being treated look like healed skin grafts for now.
Even if it did work well and got 80-90% they would still want to see a large sample size of various defects/wounds to prove its consistency before they started treating acne scar victims with whatever method they see fit. Its too early and too risky to be ringing around surgeons asking if they can slice your face up and use a product that may not give you what you want. I wouldnt consider this until you know for sure and seen photos.
8 hours ago, surgical scar said:What is incredibly invasive? Excising the scar tissue is standard procedure for scar revision. I'm willing to try it no matter how invasive or risky it is.Is he willing to accept patients with pre-existing scars at all?
Sniffy pretty much nailed this one. No doctor will outright recommend SkinTE right now (regardless of what, if any, results they've seen) for acne scarring because it's not being used for that and no final results are even available. I personally wouldn't want to try it until the results on the first patients had come out. I'd want to have a clear idea of what I could expect.
If Kim6266 pressed this doctor, or another, she might be able to convince them to do it right now, but even that is a long shot. More than likely a doc would say they'd at least want to wait until the final results come in from the first batch of patients.
In terms of invasiveness, while it's true that scar excision is a standard procedure, it's not the only one for acne scarring. Subcision, injectables, lasers etc. all get used as much if not more than excision. Plus, I think the invasiveness comment really comes from the skin biopsy of healthy tissue that takes place for SkinTE. None of the standard methods take a chunk of healthy skin to work.
On 1/10/2018 at 11:58 AM, damnBOY said:On 1/10/2018 at 11:54 AM, golfpanther said:the injectable product of skinte may not lead to margin because margin happens from the excision
Don't they need to create a wound to inject SkinTE over it? They need to remove the scar tissue anyway.
14 hours ago, golfpanther said:In terms of invasiveness, while it's true that scar excision is a standard procedure, it's not the only one for acne scarring. Subcision, injectables, lasers etc. all get used as much if not more than excision. Plus, I think the invasiveness comment really comes from the skin biopsy of healthy tissue that takes place for SkinTE. None of the standard methods take a chunk of healthy skin to work.
Why do they need to do biopsy on healthy skin? In case of skin graft or scar revision?
26 minutes ago, surgical scar said:Don't they need to create a wound to inject SkinTE over it? They need to remove the scar tissue anyway.
Why do they need to do biopsy on healthy skin? In case of skin graft or scar revision?
SkinTE's paste is made from using the skin biopsy of healthy tissue. They harvest the skin biopsy and then use 3D bio-printing to create the paste. I'm not going to pretend to understand the ins and outs of the science, but the gist is that Lough believes that LGR6 cells promote skin regeneration. So they seed the biopsy with those cells by inducing their development with the protein alpha defensin 5 (HAD5). This is all available on their site. The more LGR6, the more the wound is guided to complete regeneration. This is what worked in pigs and what they hope works in humans.
No matter what, the current product SkinTE needs a biopsy because they need to process it to create more LGR6 cells. I'm guessing that if SkinTE works (which no one knows right now if it will) their plan for injectables is to induce LGR6 proliferation by pumping a scar site full of HAD5. However, I do wonder at that point if they'd be able to go straight to market or have to go through trials with that kind of derivative.
1 hour ago, ScarRight said:Just down another lazy 5% on early trading for our skin TE supporters.
You imply by writing "our SkinTE supporters" that there are at least two sides on this boardthose that support SkinTE and those that don't. Why on Earth would any of us on this site, ostensibly dealing with scars and wanting a fix, NOT support the SkinTE product?
I don't care if someone believes it will work or notno one on this board that makes a claim either way is doing anything more than speculating. However, I definitely support the product and the company's aim to deliver complete regeneration. If it flops, I can accept that. If it totally succeeds, I'll be thrilled. If it's somewhere in between, I'll be hopeful for the progress. But jeez, shouldn't we all support any company that's trying to do this? It's almost like some of us on this board want any product that comes out for scars to fail. Why? To be right?
The divisiveness on this site makes zero sense and baffles me. When I read an article about PolarityTE that worried me, I acted. I got in touch with Swanson and asked him several pertinent questions over the course of a half hour. Everyone on this board could do what Kim6266 is doing and contact offices to find out if it's being used and where if you doubt the press release. You could try to hunt down results from the same places.
Lastly, you can find online if the ownership of any company has sold or bought shares of their own company over the last year. In the past 12 months PolarityTE has only bought more shares. Their company is small, so any selloffs or buys create huge volatility. If the owners start selling, yes, be worried. If it completely craters, be worried. But barring that, if the owners are still in and not budging (or even buying more), the stock thing is getting too much attention. If SkinTE was a complete flop and it was known at this point don't you think the owners would have sold shares by now? Especially those on this board that seem to think PolarityTE was founded by evil doctors that just wanted to exploit the market and the very people they all set out to help.
2 hours ago, ScarRight said:Just down another lazy 5% on early trading for our skin TE supporters.
If skinTE fail then forget about scarless healing for the near future so don't come here and post anything you waste your time you don't support skinte stay with your scars bro
Just to show how silly all this stock stuff is right now, after ScarRight's post this morning about it being down 5% it is now down only 1.24% for the day (with about an hour left). That 1.24% represents a mere $.26 decrease in the stock price. Some people got out, now some people are buying in. By and large investors base their decisions on trends and stock formulas and without results that's all they have to go on with PolarityTE.
3 hours ago, damnBOY said:5 hours ago, ScarRight said:Just down another lazy 5% on early trading for our skin TE supporters.
If skinTE fail then forget about scarless healing for the near future so don't come here and post anything you waste your time you don't support skinte stay with your scars bro
Down 3.59% on final bell. The problem is this has had multiple days in a row of falling. Not a good sign.
On 27.1.2018 at 10:46 PM, CoconutRough said:Laughable? Why so huffy?
Don't you see that alot of ppl who post in this thread rather need psychological help than believing in a technology that's not going to happen?Ppl are so lost that they can't even stop posting here. That's the real tragedy.
after insulting each other..
For the millionth and last time: there is thread dedicated to emotional stress caused by acne and scars. Seriously, is it really that hard to understand?
51 minutes ago, Frasier said:On 1/27/2018 at 1:46 PM, CoconutRough said:Laughable? Why so huffy?
Don't you see that alot of ppl who post in this thread rather need psychological help than believing in a technology that's not going to happen?Ppl are so lost that they can't even stop posting here. That's the real tragedy.
after insulting each other..For the millionth and last time: there is thread dedicated to emotional stress caused by acne and scars. Seriously, is it really that hard to understand?
Yes, this x1000. I suspect we all struggle with emotional stress caused by our scarring, but this isn't the board for it. I wish we could just focus on tangible and verifiable info rather than having people come here whenever there isn't any news to drum up fear and panic.
An interesting article about research on skin regenration.
http://www.cbc.ca/news/canada/calgary/reindeer-antler-regeneration-human-skin-medicine-1.4449054
Quote
n preclinical testing, we observed that SkinTE regenerated full-thickness skin complete with all of its layers (epidermis, dermis, hypodermis) and functional appendages, including hair follicles, sweat glands and sebaceous glands. Thus far, in the early stages of the human clinical application of SkinTE, we have observed results that are correlative with our preclinical observations. NEWS FROM POLARITY GO TO THEIR FACEBOOK PROFIL skinTE IS WORKING
1 hour ago, damnBOY said:n preclinical testing, we observed that SkinTE regenerated full-thickness skin complete with all of its layers (epidermis, dermis, hypodermis) and functional appendages, including hair follicles, sweat glands and sebaceous glands. Thus far, in the early stages of the human clinical application of SkinTE, we have observed results that are correlative with our preclinical observations. NEWS FROM POLARITY GO TO THEIR FACEBOOK PROFIL skinTE IS WORKING
Great post!
Correlative is an interesting word to use, but it's definitely good news. I briefly read over the pertinent things in their 10-K filing (a lot of it is info for shareholders about risk factors for the business outside of the resultsi.e. protection for their IP, possibly infringing on IP of others etc.) and they mention the results being correlative around 5 times. They also say that the product has been used on human patients since November 2017.
With this news coming out can we at very least stop the posts on this board about how SkinTE is not a product and not being used? It's clear that it's on patients and early on it's providing healing that at least is similar to what happened in pigs.
Also, with the 10-K coming out and patients having received the product in November of last year, I think it's safe to say actual results (photos, patient cases etc.) will be coming pretty soon.
Positive news from PolarityTe. I dont think its a panic move regarding stock price dip, that seems like a reach. They would have been expecting some sell offs before results being released. Some investors were getting worried because it was quiet from the PolarityTe team for some weeks also but what could they really come out and say during that period? Not much. And the evil doctor/scam conspiracies seems far fetched. That concern stems from not being used to hearing good news like this that this is maybe very real and promising. You shouldnt be convinced your acne sacrring days are behind you until you see it in the mirror anyway.
So if early results are corresponding with the pig models results then its very very positive news, getting all layers completely regenerated and appendages from replacing scarred old skin grafts for exmaple would be impressive as they are claiming here... But of course we will be the official judges of that when we see photos. The major question for us remains how "scarless" is the new skin in these patients assuming it has complete regeneration? Is it the entire wound area or just in patches that have completely regenerated?
Im curious If it wasnt completely 100% scarless skin could the procedure be repeated for any residual minimal scar tissue that remained?