Acne.org Products
24 minutes ago, fingasz said:If this works for burn damage why should it not work for acne scars? what about wrinkles? Will old people be able to have young, youthful skin? I don't think this is anywhere near possible. Like its too good to be true.
This targets scar tissue and prevents scar tissue. It has nothing to do with skin aging. Two different things.
32 minutes ago, nikkigirl said:I still have not heard anybody from Polarity say if it will work on acne scars. I posted twice on their facebook page and e-mailed them on their site. It has been mostly used on skin grafts and burn victims. A nurse posted that she loved the results on burn patients though.
A couple things. One, in looking quickly at their FB page, they don't respond to anyone. I doubt they use that for anything more than another hub that they can disseminate information. Social media is a full-time job at most companies and I don't think PolarityTE is at the point where that's necessary and it may never be something they invest time and money in.
Two, it's not really the place for them to go into details about their results. It's also possible they haven't used it specifically for acne scars so they can't comment yes or no.
I see the comment about nurses raving about the product, but that's not from a nurse it's from someone claiming nurses are liking the results. Still, good news, but I would take everything with a grain of salt by some random poster on FB. And I say this while admitting I'm hopeful SkinTE will work.
In terms of acne scars working, there isn't any reason to think it won't. I feel like we've been over this countless times but the way the product works is to excise the scar tissue and apply SkinTE. After excision, the scar tissue is gone and it makes no difference how it occurred. You just have a wound bed.
I think the better question for Polarity is do they think it will work on all parts of the body. For example, all the research being done on skin regeneration heavily implicates hair follicles as playing an important role. What if I have a scar on the bottom of my foot or I have a diabetic ulcer there? This doesn't probably affect most anyone on here (hair is on the face obviously), but it's important to know. Also, different parts of the body have different tensile strength and elasticity. Will it still heal a relatively tighter part of the body the same as a loose one? BTW, I asked Dr. Swanson this when I spoke to him and he said they believe it will work on all parts of the body, but I didn't bring up the specific things I mentioned above.
I'm sure all or most of this is going to be answered in a few short weeks to months as the results come out.
28 minutes ago, fingasz said:If this works for burn damage why should it not work for acne scars? what about wrinkles? Will old people be able to have young, youthful skin? I don't think this is anywhere near possible. Like its too good to be true.
While I do at times think the same way (it's too good to be true) you could say that about every major breakthrough in any field prior to it happening. Flight, cars, antibiotics the list goes on and on of advancements that were one day thought to be impossible. SkinTE may or may not get complete regeneration right out of the gate, but we'll know soon. I do believe that PolarityTE is committed to working on their products to achieve optimal results over time should the need arise.
14 hours ago, SimpleMutton said:Are you sure they don't have it at the Utah Hospital in Salt Lake City? Maybe the woman you talked to didn't know it
The woman could have been wrong. I would not take her word for it. I just didn't press any more or ask to speak to anyone else because then I found out they are using it as John Hopkins so I called there. HOwever all the docs were closed this week so I will try on Tuesday. HNY
6 hours ago, golfpanther said:A couple things. One, in looking quickly at their FB page, they don't respond to anyone. I doubt they use that for anything more than another hub that they can disseminate information. Social media is a full-time job at most companies and I don't think PolarityTE is at the point where that's necessary and it may never be something they invest time and money in.Two, it's not really the place for them to go into details about their results. It's also possible they haven't used it specifically for acne scars so they can't comment yes or no.
I see the comment about nurses raving about the product, but that's not from a nurse it's from someone claiming nurses are liking the results. Still, good news, but I would take everything with a grain of salt by some random poster on FB. And I say this while admitting I'm hopeful SkinTE will work.
In terms of acne scars working, there isn't any reason to think it won't. I feel like we've been over this countless times but the way the product works is to excise the scar tissue and apply SkinTE. After excision, the scar tissue is gone and it makes no difference how it occurred. You just have a wound bed.
I think the better question for Polarity is do they think it will work on all parts of the body. For example, all the research being done on skin regeneration heavily implicates hair follicles as playing an important role. What if I have a scar on the bottom of my foot or I have a diabetic ulcer there? This doesn't probably affect most anyone on here (hair is on the face obviously), but it's important to know. Also, different parts of the body have different tensile strength and elasticity. Will it still heal a relatively tighter part of the body the same as a loose one? BTW, I asked Dr. Swanson this when I spoke to him and he said they believe it will work on all parts of the body, but I didn't bring up the specific things I mentioned above.
I'm sure all or most of this is going to be answered in a few short weeks to months as the results come out.
While I do at times think the same way (it's too good to be true) you could say that about every major breakthrough in any field prior to it happening. Flight, cars, antibiotics the list goes on and on of advancements that were one day thought to be impossible. SkinTE may or may not get complete regeneration right out of the gate, but we'll know soon. I do believe that PolarityTE is committed to working on their products to achieve optimal results over time should the need arise.
I hope you are right and this stuff works. Even if it gets 50 per cent improvement....that is far better than anything we have now.....next thing is the price because i doubt if insurance will cover it because it is cosmedic in nature. The last thing is when doctors nationwide will have it.
Well if this does become even remotely successful, it couldn't be any worse than Fraxel and CO2 lasers.
3 hours ago, nikkigirl said:I hope you are right and this stuff works. Even if it gets 50 per cent improvement....that is far better than anything we have now.....next thing is the price because i doubt if insurance will cover it because it is cosmedic in nature. The last thing is when doctors nationwide will have it.
A very real concern. Let's say this gets FDA approved and it has been shown to be 50% better than all the current treatments. Using this service could initially cost 10,000s. Lets hope not, but you wouldn't think it will be a cheap procedure.
1 hour ago, ScarRight said:Well if this does become even remotely successful, it couldn't be any worse than Fraxel and CO2 lasers.
A very real concern. Let's say this gets FDA approved and it has been shown to be 50% better than all the current treatments. Using this service could initially cost 10,000s. Lets hope not, but you wouldn't think it will be a cheap procedure.
Doesn't look so hard to perform. They create another wound by taking 2 cm of healthy skin and then grow some glue like substance in a lab, they say they grow the skin in their facilities and then compact their product into that liquid like substance. Then this glue or liquid is applied on an old existing wound and they leave it to heal naturally. There's really not much to it. A laser is expensive because those machines are expensive to buy, so getting laser treatment is not cheap.
You might argue that growing the skin in a lab and compacting it into a liquid paste is where it can be costly. I do believe if they want to be successul as a start up, assuming they can achieve 50% or even more scar improvement, they must have competitive rates. I also find they seem to be quite reputable. Also, I believe if they are successful and charge an arm and leg, others will jump on the opportunity and try to come out with something better. That's how prices will become more competitive. There's Sunogel and another team headed by Dr. Cotsarelis which might be waiting to see what SkinTE can do before they jump in.
Anyways, I will give you a little scoop. Their technology relies on LGR-5 cells. These instruct skin to regenerate in shallow wounds but are unable to do the same in more severe wounds. They seem to have found a way to induce these cells to instruct skin to regenerate in more severe wounds. They claim the discovery will help achieve other organ regeneration as well. It remains to be seen.
54 minutes ago, DinkumFridge said:Where does it come from? 50% better than all treatments? What other information do you have?
I was throwing a hypothetical figure out there as an example. Of course it could be better or it may in fact be a complete flop on humans. It remains to be seen what actually happens.
11 hours ago, Candy Says said:there was a thread started by @Bingaabout some clinical trials foracne scars. They must had finish trials in December. 30 participants as I remember. This thread was moved to Scarless Healing and now I cant find the original post. @Bingayou must remember it.
sorry for english
https://clinicaltrials.gov/ct2/show/NCT03056235?cond=acne+scar&rank=1
15 hours ago, ScarRight said:Well if this does become even remotely successful, it couldn't be any worse than Fraxel and CO2 lasers.
A very real concern. Let's say this gets FDA approved and it has been shown to be 50% better than all the current treatments. Using this service could initially cost 10,000s. Lets hope not, but you wouldn't think it will be a cheap procedure.
ReCell is a comparable product in terms of the process and I've read that it costs 2,500 and will come in around $3,500-$5,000. There very similar in terms of the steps involved: skin biopsy, sent to lab for processing, returned to doctor, excision or scar tissue and then application of product and dressing.
That is by no means cheap, but it's significantly less than 10K. I say this while recognizing that if SkinTE attains complete regeneration, they could likely charge far more than ReCell, which would be a far inferior product at that point. But the only basis they'd have for doing so would be the results, not the actual steps in the procedure, which would draw pretty sharp criticism IMO.
Also, here's the lease PolarityTE signed for their new building:
I haven't read too much of that but I think it's quite encouraging that they signed a five-year lease at that cost. SkinTE is already on patients so making this move now and locking themselves into a high-cost lease means, at the very least, they think it's going to better than anything else out there. If early data showed a complete flop, there is no chance they'd put themselves at this much risk with little to no way to make up the costs with the sale of the product.
Considering they started to treat Patients with SkinTE almost 3 weeks ago (half december) and they said most of the regeneration happen in the first month (with residual regeneration in the following 2 months) we should expect some pics fairly soon.
They also need financing so if the results are good they have to show it to attract investments in the company.
I hope by the end of January we have at least a pic of skin regenerated in a man.
12 minutes ago, SimpleMutton said:Considering they started to treat Patients with SkinTE almost 3 weeks ago (half december) and they said most of the regeneration happen in the first month (with residual regeneration in the following 2 months) we should expect some pics fairly soon.
They also need financing so if the results are good they have to show it to attract investments in the company.
I hope by the end of January we have at least a pic of skin regenerated in a man.
Yeah, we should expect results very soon, especially if it's showing hair growth and complete regeneration. They'll want to get that out pronto to bring in more cash flow. I'm still amazed by how quickly they've made everything happen. At first that made me skeptical, but with it on patients and them getting that facility, I'm eagerly awaiting the results.
They'll likely be some news coming out of the conference they're attending on January 8th and 9th.
14 hours ago, ScarRight said:I was throwing a hypothetical figure out there as an example. Of course it could be better or it may in fact be a complete flop on humans. It remains to be seen what actually happens.
Yes..we were just saying if it does give 50 per cent improvement.It may be better or worse but for people to empty their pockets with money it better have good results.
I tell you what - they're a lot of people whom are riding their hopes on this invention. I just hope it doesn't give out false hope, as a lot of people would be crushed. I simply refuse to believe it until I see it. Even if the current trials are successful, it could be several years away.
8 hours ago, ScarRight said:I tell you what - they're a lot of people whom are riding their hopes on this invention. I just hope it doesn't give out false hope, as a lot of people would be crushed. I simply refuse to believe it until I see it. Even if the current trials are successful, it could be several years away.
Acne is crushing as it is and then as the pimples heal they leave pits. For others, they leave raised scars as if someone had healed from deep lacerations. That's the most devastating part of it. If our body just regenerated the lost skin when healing, this forum would not exist.
I have lots of pits on my face although angle lighting makes a big difference in their appearance. Too others on this forum, they may look severe. To me, I have seen far worse. They are all less than 5 mm wide. My left cheek looks far worse than my right. I've got some pits on my temples too. My cystic acne also left me with scarring on the shoulders and back. Those are mostly of the raised type. I was diagnosed with acne conglobata and severe joint paint in my teens. I'm still surprised my scarring is not worse.
Anyways, I would love for these pits to go but they won't. I accepted my sad rotten skin in my twenties and moved on. I realized there's no cure for this and the breakouts will follow me to my deathbed. I couldn't continue being fixated on my skin and had a life. Surpringly, simply not caring rid me of most of the cysts and as I got older, the breakouts reduced in intensity. I still get breakouts in my thirties and I pretty much tried all kinds of things to stop the breakouts apart from Accutane. At times, I feel like I'm rotting from the inside.
If SkinTE does not work, it will not matter. I still got to get up and go to work the next day.Others have missing limbs and incurable diseases. For acne sufferers, they have been blessed with horrid skin. So nobody is perfect. You gotta accept what you're given and make the best out of it. But that doesn't stop you from searching for a solution.
The hard part of accepting your scars and letting go is when you see others having smooth skin. You feel hopeless because you know you can never have that again. I let my beard grow to cover my scarring. I don't care about the stares or comments from others. Surpringsily however, nobody has ever noticed my scars. Most negative comments are for the grossly looking beard I wear to cover them. Sometimes, it can all be in your head as well.
My visits to dermatogolists were not pleasant so I lost faith in modern medicine. I really don't believe SkinTE will get you complete regeneration but they are moving fast which is promising. If it works, the creators are looking to cash in big time so their invention will not take years to release contrary to your reasoning.
My concerns have to do mostly with ethics and skin sensation. Assuming it works, will the regenerated skin look and feel the same to the patient? Will all the skin sensation be restored? Will it work on wounds previously healed by scar tissue. How much scar tissue must be removed? How do I feel giving access of my DNA to them? How will they dispose the skin that has been regenerated in labs or the skin that they took as a biopsy to create their product in the lab?
Anyways, posting such comments does not help. If it doesn't work in the end, it was worth believing. I am pretty sure others will take a shot at complete skin regeneration again somewhat in the near future. If it does work then why not take a risk and go get a permanent solution for these scars to help your self-esteem?
The thing about people who keep harping on about 'refusing to believe' in SkinTE are the ones who keep coming back to this thread time and time again to check. It seems to me that these people are only saying such things to keep their own anticipation in check rather than that of others. Any reasonable person knows not to count their chickens before they hatch, and the few that are already getting excited over SkinTE without even knowing whether they work deserve to be disappointed if it doesn't work. So when you keep posting such pointless things, what is your motivation? Do you really have some weird altruistic objective to keep random people from being disappointed in a product you don't have financial relations to, or do you have such little self-discipline that you need to post on a public forum to keep yourself in check?
I actually read the first page of this gigantic thread. Quite fascinating reading. Some people back in 2007 predicted it will be 20 years away, while others said it will be available to the US market in 2009/10. I will be very keen to see how this little Nasdaq company goes in 2018 and beyond.
Thats the thing; back in 2007 ten years looked so far away. Well, now it is 2018. Weare getting there.
One thing I would like to say is that yes, we have been through bad times, even horrible times. But to be truly happy I think you need the bad parts as well. Those with nice skin dont even think about it on daily basis which means they dont even appreciate it. On the other hand, imagine how we will feel the day our scars are in the past.
9 minutes ago, Frasier said:On the other hand, imagine how we will feel the day our scars are in the past.
A very big 'what if' still. Working on pigs is one thing, but working on humans is another. I have accepted the way I look. My way of thinking is that is would be a very nice bonus if this could improve my scars, I would def cough up the money for the treatment (providing it is safer than lasers, which I would never use).
2 hours ago, ScarRight said:I am realistic. And I do not need this treatment to work. If it doesn't, I am happy with the way I look (mostly).
Some people do need it to work though and can't be happy with the way they look
Personally I do believe scarless healing (or almost scarless) is possible, it's not that far fetched to visualize it.
After all, skin already regenerate itself and only develop a scar because it has to "rush" the process because of the risk of infection. Evolution favored that skin regenerated this way. Probably back in time people that regenerated skin quickly but with a scar survived better than people that could regenerate perfect skin but more slowly and so risked to develop infections and die.
What we have to attain isn't something that biology already doesn't do. We aren't trying to regenerate a natural (not artificial) leg after an amputation, we aren't trying to develop a third eye.
We're just trying to regenerate skin the way it would already regenerate itself if infections weren't a problem.
The fact that in 2018 there is still no cure to scars is because research was always lacking in this "field".
Everybody saw acne scars as just a cosmetic problem so not worth to put billions of research in.
Only recently they started to research treatments for scars.
All the treatments that were credited to treat acne scars were actually invented for other things....
Lasers, fillers, peelings ecc were mainly anti aging (anti wrinkles) treatments that were then used to treat acne scars too.
Even SkinTE was mainly invented for treating burns but it will also be used for ance scars if successful.
Acne was the same. Nobody give a fuck to develop a real treatment for acne. Even Accutane wasn't invented because they were looking for a treatment for acne. They couldn't care less.
They were looking for a treatment for cancer and then they found iserotretinoin worked for acne and so they marketed it.
If only they would seriously research a cure for acne and acne scars we would already have it.
Anyway I'm optimistic about SkinYE because I do believe regenerating skin without scars isn't that hard at all.