Acne.org Products
17 minutes ago, Anish004 said:1 hour ago, rudy1986 said:News Of The Year.....
Let's cross our fingers that this will succeed cause I am sure other big players will enter the game with similar products for us!The whole landscape of regenerative medicine will change.
Yup, good to see them make it official with a press release. It makes more sense to me now whey they would take my call and talk to me so openly since this press release was already in the works.
Ps93, agree. If SkinTE works everything will change throughout the field of medicine. And how awesome is it that Lough, even after it's been used on patients, is doubling down and saying he believes that they'll be able to replicate their pre-clinical success with full-thickness, hair-bearing skin. I mean, it's already been applied... it' not like he's speaking entirely in the dark here. It's been used.
13 hours ago, c0017 said:
Yeah, the good news keeps coming today. Hopefully this is a sign that Sun is going to get funding and really make a go of Sunogel as a company. I still think he'd be wise to sync up with someone on the business side of things that has experience in the medical field.
I'm still shocked by how simple Sun's approach is. I mean, look at those photos! They made a wound, made a hydrogel piece of the same size, popped it in and bam, complete regeneration in mice and pigs. That's amazing.
42 minutes ago, golfpanther said:Yeah, the good news keeps coming today. Hopefully this is a sign that Sun is going to get funding and really make a go of Sunogel as a company. I still think he'd be wise to sync up with someone on the business side of things that has experience in the medical field.I'm still shocked by how simple Sun's approach is. I mean, look at those photos! They made a wound, made a hydrogel piece of the same size, popped it in and bam, complete regeneration in mice and pigs. That's amazing.
What I like in this article, it is that he mentions the term " perfect skin "
10 minutes ago, slave of jesus said:52 minutes ago, golfpanther said:Yeah, the good news keeps coming today. Hopefully this is a sign that Sun is going to get funding and really make a go of Sunogel as a company. I still think he'd be wise to sync up with someone on the business side of things that has experience in the medical field.I'm still shocked by how simple Sun's approach is. I mean, look at those photos! They made a wound, made a hydrogel piece of the same size, popped it in and bam, complete regeneration in mice and pigs. That's amazing.
What I like in this article, it is that he mentions the term " perfect skin "
Agreed. What's wonderful about both PolarityTE and Sunogel is that neither are backing down at all from their claims. Lough said they fully believe that SkinTE will get the same results in humans as they achieved in pigs and Sun has said the same for his hydrogel. I just love the idea of Sunogel because of how easy/likely cheap the whole process would be.
With PolarityTE though, they're already using the product on all types of scarring so they have a huge head start.
Hmm, I wonder how difficult it would be to excise face skin for SkinTE application? Would entire cheek be excised minimising margin lines, or would many smaller excisions be required. Seems like some major surgery with serious care required. Also, would blood vessels regenerate too? Great news anyway..
43 minutes ago, eekman said:Hmm, I wonder how difficult it would be to excise face skin for SkinTE application? Would entire cheek be excised minimising margin lines, or would many smaller excisions be required. Seems like some major surgery with serious care required. Also, would blood vessels regenerate too? Great news anyway..
they will inject the skinte if you don't want to make excisions
1 hour ago, JohnRottenSkin said:yeah. still so many questions
This is true too many questions exist but if it is successful I think many of us will be willing to undergo all the process despite the aftercare that might be needed.Also I assume that many other projects will be backed up by company giants like Cotsarelis research so as to be able to take a piece of the pie that will be created.
9 hours ago, Anonymouz1 said:Sunogel seems more practical to use. From my understanding, you place it on existing scars and it regenerates skin. No excising the existing scar. I wonder when the product will enter clinical stages.
No, you still need an open wound to use sunogel.
13 hours ago, eekman said:Hmm, I wonder how difficult it would be to excise face skin for SkinTE application? Would entire cheek be excised minimising margin lines, or would many smaller excisions be required. Seems like some major surgery with serious care required. Also, would blood vessels regenerate too? Great news anyway..
No way, not unless you have burns or skin grafts. I'm sure their subsidiary products will work for acne scars but you will have a tough time finding a surgeon who is going to risk cutting your face up for acne scars.
9 hours ago, Anonymouz1 said:Sunogel seems more practical to use. From my understanding, you place it on existing scars and it regenerates skin. No excising the existing scar. I wonder when the product will enter clinical stages.
That, sir, is not how sunogel works.. it has to be excised
I expect one of the major differences between Sunogel and SkinTE (if either end up working as desired) would be the size of the wound they are capable of regenerating in one procedure. I imagine SkinTE might be able to cover larger wounds than Sunogel since it provides the body the building blocks, so to speak, whereas Sunogel requires the body to do more work. This is all just baseless conjecture though.
33 minutes ago, FastMedia said:No, you still need an open wound to use sunogel. No way, not unless you have burns or skin grafts. I'm sure their subsidiary products will work for acne scars but you will have a tough time finding a surgeon who is going to risk cutting your face up for acne scars.
Scar revision surgery happens all the time today. A quick google search will show many large pieces of skin being excised on the face for a variety of reasons. Id agree that acne scars arent the typical use, but it happens now and if complete regeneration were available you can bet it would happen more.
Sunogel does need an excision, but unlike SkinTE it doesnt need another excision for the skin biopsy.
I wonder if a surgeon
1 hour ago, FastMedia said:No, you still need an open wound to use sunogel. No way, not unless you have burns or skin grafts. I'm sure their subsidiary products will work for acne scars but you will have a tough time finding a surgeon who is going to risk cutting your face up for acne scars.
Yeah, I don't think surgeons will want to excise skin (especially if the area is big) for acne scars revision. That seems like too risky...
They excise skin if you have skin cancer or something like that, not for a simple acne scars removal.....I hope they understand how distressing bad acne scars can be
56 minutes ago, SimpleMutton said:I wonder if a surgeon
Yeah, I don't think surgeons will want to excise skin (especially if the area is big) for acne scars revision. That seems like too risky...
They excise skin if you have skin cancer or something like that, not for a simple acne scars removal.....I hope they understand how distressing bad acne scars can be
Derms do excisions for ice pick scarring.
2 hours ago, golfpanther said:Scar revision surgery happens all the time today. A quick google search will show many large pieces of skin being excised on the face for a variety of reasons. Id agree that acne scars arent the typical use, but it happens now and if complete regeneration were available you can bet it would happen more.Sunogel does need an excision, but unlike SkinTE it doesnt need another excision for the skin biopsy.
It would be nice if someone could enlighten me on how Sunogel works. It seems simpler to just excise the scar, apply the gel and allow for regeneration. However, SkinTE is moving fast while Sunogel has been around for some time (from my own research) but they are not moving as fast. It seems the creator of Sunogel is also easy to reach.
1 hour ago, Anonymouz1 said:4 hours ago, golfpanther said:Scar revision surgery happens all the time today. A quick google search will show many large pieces of skin being excised on the face for a variety of reasons. I™d agree that acne scars aren™t the typical use, but it happens now and if complete regeneration were available you can bet it would happen more.Sunogel does need an excision, but unlike SkinTE it doesn™t need another excision for the skin biopsy.
It would be nice if someone could enlighten me on how Sunogel works. It seems simpler to just excise the scar, apply the gel and allow for regeneration. However, SkinTE is moving fast while Sunogel has been around for some time (from my own research) but they are not moving as fast. It seems the creator of Sunogel is also easy to reach.
This picture from their site explains it:
As you can see, it's applied to a wound. So, if you want to get rid of an existing scar you would need to excise it to create a wound bed for the hydrogel to be put into.
Sunogel was formed in 2015, but their paper detailing how they achieved complete regeneration in pigs using Dr. Sung's new DexIEME. To clarify, Sun used to work at Dr. Sharon Gerecht's lab at Johns Hopkins where they created the original dextran hydrogel (DexAE) that went on to be patented and used as the main piece of technology when Gemstone Biotherapeutics was formed. Sun's new hydrogel (DexIEME) is different the one that got "perfect skin" (pully directly from the paper) in pigs.
Here's a link to the paper. It's free to read right now since it was one of the most read papers in the last few months:
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201700659/full
I am not familiar of how the surgeon would apply either sunogel or SkinTE but apart from excision couldn't they use a laser to burn the different layers of the scar so as to find where it begins since each one of us has different depth of scars(it might be supid what i said but I have no idea how would they do it for acne scars.)In my opinion from what we have read so far Cotsarelis seems to be the less invasive since from my understandind it does reprogramming in the skin but it might be years away.If at the end excision is needed many surgeons or dermatologists will find a way since this will be billion dollars game.
33 minutes ago, Ps93 said:I am not familiar of how the surgeon would apply either sunogel or SkinTE but apart from excision couldn't they use a laser to burn the different layers of the scar so as to find where it begins since each one of us has different depth of scars(it might be supid what i said but I have no idea how would they do it for acne scars.)In my opinion from what we have read so far Cotsarelis seems to be the less invasive since from my understandind it does reprogramming in the skin but it might be years away.If at the end excision is needed many surgeons or dermatologists will find a way since this will be billion dollars game.
look polrityte said that they can inject skinte into scars this will be not invasive
21 hours ago, golfpanther said:Scar revision surgery happens all the time today. A quick google search will show many large pieces of skin being excised on the face for a variety of reasons. Id agree that acne scars arent the typical use, but it happens now and if complete regeneration were available you can bet it would happen more.Sunogel does need an excision, but unlike SkinTE it doesnt need another excision for the skin biopsy.
Yes, with small bits of skin. I would encourage you to ask a plastic surgeon if you are so sure.
16 hours ago, Ps93 said:I am not familiar of how the surgeon would apply either sunogel or SkinTE but apart from excision couldn't they use a laser to burn the different layers of the scar so as to find where it begins since each one of us has different depth of scars(it might be supid what i said but I have no idea how would they do it for acne scars.)In my opinion from what we have read so far Cotsarelis seems to be the less invasive since from my understandind it does reprogramming in the skin but it might be years away.If at the end excision is needed many surgeons or dermatologists will find a way since this will be billion dollars game.
Reprogramming, like in Cotsarelis method, will likely be years away because that wouldn't be considered a device by the FDA. In light of recent FDA changes, it could reach the market sooner than before but it would most likely still need to go through all 3 phases of a clinical trial.
In terms of lasering away different layers of skin, I have no idea if that would work and I don't think PolarityTE or Sunogel do at this time either. They have only done full-thickness excisions to achieve their results to this point It's possible, especially with PolarityTE, that they're testing different excision layers but that's speculation on my part.
2 hours ago, FastMedia said:On 12/16/2017 at 4:35 PM, golfpanther said:Scar revision surgery happens all the time today. A quick google search will show many large pieces of skin being excised on the face for a variety of reasons. Id agree that acne scars arent the typical use, but it happens now and if complete regeneration were available you can bet it would happen more.Sunogel does need an excision, but unlike SkinTE it doesnt need another excision for the skin biopsy.
Yes, with small bits of skin. I would encourage you to ask a plastic surgeon if you are so sure.
I've seen plenty of pictures where large portions of the face are excised for scar revision in a variety of different wound types (acne, traumatic injury, burns etc.) I do agree that it's really invasive, and as Swanson pointed out, SkinTE as it is now is mostly for large burns so it would be up to patient and provider to determine if the use was worth it. But as Ps93 said, if it gives complete regeneration, we're talking a multi-billion dollar industry. Everyone will want to get in on it, which will make finding a great surgeon who is comfortable using the products essential.
22 hours ago, golfpanther said:This picture from their site explains it:
As you can see, it's applied to a wound. So, if you want to get rid of an existing scar you would need to excise it to create a wound bed for the hydrogel to be put into.
Sunogel was formed in 2015, but their paper detailing how they achieved complete regeneration in pigs using Dr. Sung's new DexIEME. To clarify, Sun used to work at Dr. Sharon Gerecht's lab at Johns Hopkins where they created the original dextran hydrogel (DexAE) that went on to be patented and used as the main piece of technology when Gemstone Biotherapeutics was formed. Sun's new hydrogel (DexIEME) is different the one that got "perfect skin" (pully directly from the paper) in pigs.
Here's a link to the paper. It's free to read right now since it was one of the most read papers in the last few months:
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201700659/full
Thanks. That was very informative. So this would require the scar to be excised.
2 hours ago, golfpanther said:Reprogramming, like in Cotsarelis method, will likely be years away because that wouldn't be considered a device by the FDA. In light of recent FDA changes, it could reach the market sooner than before but it would most likely still need to go through all 3 phases of a clinical trial.In terms of lasering away different layers of skin, I have no idea if that would work and I don't think PolarityTE or Sunogel do at this time either. They have only done full-thickness excisions to achieve their results to this point It's possible, especially with PolarityTE, that they're testing different excision layers but that's speculation on my part.
I've seen plenty of pictures where large portions of the face are excised for scar revision in a variety of different wound types (acne, traumatic injury, burns etc.) I do agree that it's really invasive, and as Swanson pointed out, SkinTE as it is now is mostly for large burns so it would be up to patient and provider to determine if the use was worth it. But as Ps93 said, if it gives complete regeneration, we're talking a multi-billion dollar industry. Everyone will want to get in on it, which will make finding a great surgeon who is comfortable using the products essential.
If you do a simple search of scars, you will see all kinds of people with extensive scarring. Some of us here are far better off with acne scars than we think. I think all these scar elimination innovations are aimed towards helping people with extensive scarring first including those with the severe dents left over from acne conglobata for instance.
Right now, all these new methods are aimed at people who have suffered from burn injuries and others who had big chunks of skin completely vaporized following trauma. I believe minor acne scarring is the least of the priorities right now. The good thing about this is if it works on wounds such as lacerations, chronic ulcers or burns, then all those ex-acne facial dents will be an easy fix.
We can see them directly sunogel or polarity? Malheuresement, me I live in France. My question is certainly stupid !But pk not give it a try for a person who lives in usa.There is nothing to lose.There is address of sunogel on the Internet :9 W Ridgely Rd #270, Lutherville-Timonium, MD 21093, Etats-Unis