Acne.org Products
17 minutes ago, SimpleMutton said:Yes, I think many of us on this topic have bad scars, even though many that post their pics on the forum often have shallow, very limited scars damage that make me wonder why they even care about that.I had (and still have) cystic acne since I was 12yo. I'm in my late 20's now.....I had 3 Accutane treatments at very high dosages for 6 months each and never got cured of cystic acne, it only disappears for a couple of months after every course but then it returns
My entire back is absolutely devastated to the point it's incredibly hard even to see normal, non scarred, non hyperpigmentated (or hypopigmentated) skin. My shoulders and upper arms are full of white raised scars (I think like yours).
My chest still have bad cystic acne and in that area it causes me hypopigmentation when it heals.
Even in my belly and legs I have some cystic acne and scars (not as bad as in other parts).
My face of course also have cystic acne and bad acne scars all over.A product like SkinTE (or another scarless healing one) would be a miracle for me and would pay every price to get it given my condition
If I can ask you, what lifestyle changes did you implement that improved your condition?
I don't believe this thread is about acne treatments but I would answer your question.
The ones you have on your thighs, buttocks, belly and legs are not acne but folliculitis. They are caused by a bunch of bacteria or fungi. I get these now when shaving. You should disinfect the area with some sort of over the counter acid like vinegar, peroxide or alcohol. You might also be allergic to the clothes you wear. Try buying cotton based clothing only. Everytime you sweat, try to wash the area as soon as possible. Avoid wearing tight clothes. Also, try to cover the elastic waistband of your underwear. I've seen major improvement in my condition by following these steps. If it's deep, you really need to see a family doctor which will prescribe you some cream to clear that up for you.
I also avoid greasy foods, milk, caffeine and alcohol. The moment I cheat I breakout severily. The ones on your back/chest are cystic acne. Use vinegar mixed with water and apply it often with benzoyl peroxide twice a day. Shower often. Use alcohol or peroxide too. Also change tshirts often until it clears up as well as your bed sheets. You need to be aggressive about it. You can't expect a difference within a week.
However, your cystic acne can also be deep folliculitis or a deep fungal infection. As for the red spots, they are not scars but hyperpigmentation. It will go away in a few years but that white discoloration you get after is permanent. Those are hypertrophic scars which fade with time or they may be follicular macular atrophy or perifollicular elastolysis. These are caused by loss of elasticity to the skin. They are not true scars because hair comes out of them. It is similar to another condition called anetoderma. There is not much info about the condition online. You could of easily developped keloids which are an overgrowth of scar tissue covering huge parts of skin. By the sounds of what you describe, this is what you have. They are red, puffy and tender. I am lucky enough to not scar in this manner. I do form however hypertrophic scarring which flattens with time but remains white forever.
My face cleared on its own when I reached my mid twenties however now I am stuck with folliculitis from shaving.
43 minutes ago, Anonymouz1 said:I don't believe this thread is about acne treatments but I would answer your question.The ones you have on your thighs, buttocks, belly and legs are not acne but folliculitis. They are caused by a bunch of bacteria or fungi. I get these now when shaving. You should disinfect the area with some sort of over the counter acid like vinegar, peroxide or alcohol. You might also be allergic to the clothes you wear. Try buying cotton based clothing only. Everytime you sweat, try to wash the area as soon as possible. Avoid wearing tight clothes. Also, try to cover the elastic waistband of your underwear. I've seen major improvement in my condition by following these steps. If it's deep, you really need to see a family doctor which will prescribe you some cream to clear that up for you.
I also avoid greasy foods, milk, caffeine and alcohol. The moment I cheat I breakout severily. The ones on your back/chest are cystic acne. Use vinegar mixed with water and apply it often with benzoyl peroxide twice a day. Shower often. Use alcohol or peroxide too. Also change tshirts often until it clears up as well as your bed sheets. You need to be aggressive about it. You can't expect a difference within a week.
However, your cystic acne can also be deep folliculitis or a deep fungal infection. As for the red spots, they are not scars but hyperpigmentation. It will go away in a few years but that white discoloration you get after is permanent. Those are hypertrophic scars which fade with time or they may be follicular macular atrophy or perifollicular elastolysis. These are caused by loss of elasticity to the skin. They are not true scars because hair comes out of them. It is similar to another condition called anetoderma. There is not much info about the condition online. You could of easily developped keloids which are an overgrowth of scar tissue covering huge parts of skin. By the sounds of what you describe, this is what you have. They are red, puffy and tender. I am lucky enough to not scar in this manner. I do form however hypertrophic scarring which flattens with time but remains white forever.
My face cleared on its own when I reached my mid twenties however now I am stuck with folliculitis from shaving.
Thank you, I do think you're right about the folliculitis but can it leave scars? I have scars even on my calves....it's ridiculous
As for the cystic acne, my chest is where I get the most of it right now...
I also agree about food....I tend to eat very good, no greasy food, no chocolate, no soda, no alchool, no smoke, no milk and it does helps somewhat even though I get some cystic acne nonetheless....but when I eat bad, my acne is much worse
I also have a lot (tons of ) follicular macular atrophy.....it's crazy on my shoulders, upper arms
best of luck to you....let's hope skinTE is for real and can fix our skin and the scars
2 hours ago, SimpleMutton said:Thank you, I do think you're right about the folliculitis but can it leave scars? I have scars even on my calves....it's ridiculous
As for the cystic acne, my chest is where I get the most of it right now...I also agree about food....I tend to eat very good, no greasy food, no chocolate, no soda, no alchool, no smoke, no milk and it does helps somewhat even though I get some cystic acne nonetheless....but when I eat bad, my acne is much worse
I also have a lot (tons of ) follicular macular atrophy.....it's crazy on my shoulders, upper arms
best of luck to you....let's hope skinTE is for real and can fix our skin and the scars
Deep folliculitis tends to leave scars if it caused by the wonderful bacterial organism known as stapphylococcus and not treated early. This bacterial parasite normally lives on our skin and can even be found in our gut too. When it becomes too comfortable it causes infections on the skin and other life threatening conditions like cellulitis if it enters deep into the skin.
It is associated with many other acne like conditions like acne on the scalp (folliculitis decalvans), sycosis vulgaris (beard acne) and acne nuchae (acne of the neck hairline). These conditions are not true acne. All these conditions result in scarring alopecia meaning hair loss through scarring of the infected hair follicule during healing. You see our bodies are too lazy to repair the hair follicules.
I have some scars from stapphylococcus because as a kid I developed chicken pox lesions which were infected by this organism. It was caught early and the damage was minimal.
As for SkinTE, all we got is some images on a website claiming they regenerated pig skin. There is no peer reviewed articles about it. A new year is about to commence. Last year, was pretty exiting. We had Cotsarelis' discovery as well as some progress with Sunogel and SkinTE. I am hopeful, something will come of this. As for the acne vaccine, it is being developed and by 2020, it should be available. However, the most severe forms of acne are accompanied with other conditions like folliculitis and even hidrenitis. The medical community is years away from understanding the root causes of why these skin conditions happen in the first place including acne. I also wish the best of luck for you as well.
5 hours ago, Ps93 said:I agree with you except the part that the treatment will not be affordable.I am sure it will come at a very heavy price propably 50k or something similar but i think most of us would try to find that amount of musoney to transform their lives because it will be an investment to ourselves.At the end of the day why would it be affordable only for millionaires as the good profits will come from the average class and I hope they will sell it forOne question that I also have is isn,t there any billionaire that had that issue with acne scars or skin regeneration so as to look forever young that could financially back up for a research on skin regeneration so as to make it profitable and make billions out of that or do you think that with multiple treatments of hundres thousands of dollars this issue could have been eliminates for the rich people of this world?
To answer your question, I do believe some millionaire must have pioneered the idea of scar elimination, must of thrown tons of money on it and in the end nothing came of it. Most millionaires, I believe don't care about their scars and why would they? They have tons of cash. Their priorities must be elsewhere.
Who knows? They probably have found many cures to many diseases but won't release their cures to the public for now. The same could be said about scarring. It's all business.
Concerning scar free healing if SkinTE does not work I think the solution will not be far away due to the developmente of bioprinted skin which inevitably will be used for soldiers.Biodan group is supposed to have on the web page that this skin could be used for transplants even though we do not see any commercial use yet.As for the enlarged pores which are referred on this thread and it must be bothersome if not for all of us but most of us there have been many research for this issue if you check parakeratosis inhibitor patents by Sisheido even from the 90s but they have not been commercially available all those years firstly because they could give a permanent solution and cosmetic companies would like our money every month and secondly because a laser industry would face problems.I think somebody has to simply make the first step to make the change in what exists today and consequently everyone will have to follow starting from cosmetic to bioprinting companies even laser companies which could make even more efficient lasers.I hope we do know for SkinTE during December so that we know that hope exists and is out there.
10 hours ago, Ps93 said:Concerning scar free healing if SkinTE does not work I think the solution will not be far away due to the developmente of bioprinted skin which inevitably will be used for soldiers.Biodan group is supposed to have on the web page that this skin could be used for transplants even though we do not see any commercial use yet.As for the enlarged pores which are referred on this thread and it must be bothersome if not for all of us but most of us there have been many research for this issue if you check parakeratosis inhibitor patents by Sisheido even from the 90s but they have not been commercially available all those years firstly because they could give a permanent solution and cosmetic companies would like our money every month and secondly because a laser industry would face problems.I think somebody has to simply make the first step to make the change in what exists today and consequently everyone will have to follow starting from cosmetic to bioprinting companies even laser companies which could make even more efficient lasers.I hope we do know for SkinTE during December so that we know that hope exists and is out there.
7
The bioprinted skin would be at the mercy of the arduousFDA approval process. We'll all be old or dead before that gets any traction. I've emailed the WF dr'sworking on this, the software on the printer just isn't ready to be used on anyone yet. Their preclinical models showed better healing than recell and controls but it did not look better than SkinTe's.
First, I'm really sorry about all the scarring everyone has experienced on here. My scarring is not from acne but from trauma, but it probably pales in comparison to a lot of you. I have nothing but compassion and empathy for all of you.
In terms of technology being suppressed, I think there is some potential for that, but the best part about the time we live in now is that everything ends up seeing the light of day. Whether it be scandals that rock industries or price gouging for medication, companies and people just can't get away with as much as they used to and if they try it's not lasting.
I also somewhat disagree with the notion that giant companies would want to suppress complete regeneration. Yes, I get that derms and companies make a lot of money off repeated procedures that offer marginal improvement, but if complete regeneration came to fruition the market would tremendously expand.
A lot of people might find peace with their scars (especially if they aren't extremely noticeable) but some of that arises from not having a way to actually get rid of them completely. However, if a product hit the market that could give you back 100% form and function I think a lot of people might reconsider. I'm among those people. I've never gone in for anything that offers percentage improvements, but you can bet that I, and others like me, would be clamoring for complete regeneration.
Perhaps the market and big companies don't realize thisthey don't see the potential market growth from a new kind of treatmentbut I highly doubt that. There's a reason projections for regenerative medicine are around $60 billion by 2020. It's because true regeneration opens up a plethora of new patients that otherwise would be outside the market.
Plus, people will always scar (at least for the foreseeable future) so it's not like repeat business is going to vanish altogether.
A note on the FDAas others have posted they recently issued a press release detailing how they're going to streamline the process for regenerative medicine approval. I didn't dig into the details but this shift means we should be getting products to clinics faster.
Lastly, I reached back out to PolarityTE today and they just got back to me about setting up a call before 10am ET on Wednesday. I'm on the west coast so it'll be an early one for me but I'm gonna try to make it happen.
On 08/12/2017 at 3:24 AM, golfpanther said:I posted the article in the private chat some of us are on and while it isn't good news, I think it's wise to keep things in perspective. Honestly, most of that stuff revolves around stock valuation and investment, which doesn't affect or indicate the efficacy of the product one bit. It might work, it might not work, but the article's main thrust is to inform their readers about whether they should invest in the company.To me, there were 2 salient points raised: 1. Why hasn't there been peer reviewed published papers about the swine tests and 2. Why are there no clinical trials listed on clinicaltrials.gov? However, even with this there are explanations beyond, "The sky is falling and it doesn't work!"
First, it could be that since it's already been approved by the FDA and supposedly in 18 burn centers in the US (and ostensibly being used), Lough and Swanson and PolarityTE have decided it's not necessary to spend the time, money and resources on the trial and instead will just use data from clinics to prove the efficacy of the product. I hope this isn't the case, as I'd like at least a small peer-reviewed pilot trial, but I can see this as a reason.
Second, it could just be delayed and not mean much of anything beyond that.
Third, and this is the most optimistic one, they've already used it on patients and it works. At that point, why do the pilot study? This isn't like other devices or drugs that offer marginal/percentage improvement. If it works like it did in pigs then you'll just have completely regenerated skin.
Fourth, in regards to published papers when it comes to the pigs, I have no idea how long it takes to actually get into a journal and I doubt the author of the article does either. In a quick search for papers on pubmed for studies where Lough was an investigator I found one from April 17th, 2017. That is clearly after he left Johns Hopkins and formed PolarityTE so anecdotally, it seems like these things can take a while.
Lastly, I reached out to PolarityTE after reading the article and basically said that I'm very hopeful for the product but also concerned by the lack of a clinical trial and no published papers and asked for an update. To my surprise, I got a response very quickly. They said we could jump on a call for an update as early as tomorrow or next week. I'm going to do and will keep you all posted. My main questions are:
1. Has the pilot clinical trial begun? If so, do you have any results to share? If not, why and when do you estimate it will happen (if they're still pursuing this)?
2. Why haven't there been any published papers in regards to the tests done on pigs?
3. Has the product been used outside of the pilot study and if so can you share any results?
4. Is the plan to still bring SkinTE to a wide market release in the first half of 2018?
That's bout all I have. Any suggestions are welcome, but reference Tiano's convo with them before to make sure we're getting new questions/information.
1. their derivative product are planned for when approximately ? If skinte work on the human beings
2. When we shall have the results on the human ?
3. In a near future can we hope for a scar free with skinte or them their derivative products ?If it is not the case still
4. right now, we can hope a scar free for scars less serious than burn Such as a acne scar with skinte ? If it is not the case, in the futur, we can hope a scar free for scars less serious than burn Such as a acne scar with them derivative products ?
good luck guy!
Alright guys, just got off the phone with Swanson and wanted to make an update while it's fresh.
I didn't record the convo but did make notes while I was talking to him. Here goes:
1. Has the pilot study moved forward and if so, what is the update? If not, what's the cause of the delay and when will it be back on track?
Yes, they have moved forward and the product is in centers right now and being used. They cannot share data with me at this time, but the way it's going to work is that the pilot study will be just like a clinical trial: control wounds, all the same patient, being compared against split-thickness skin grafts etc. It will be heavily vetted and submitted for peer review.
Results from the actual market will be different in the sense that anything that is published will be up to the centers using the product. In Swanson's words, it will be up to the provider to release their findings on its use on their patients.
Their product is regulated by the HTP/C 361 arm of the FDA: human cells, tissues, and cellular and tissue-based products. As such there are four things that must be true to receive approval through this arm (which they already have obtained):
a) minimal manipulation
b.homologous use
c) certain factors cannot be added
d) because it's autologous (from patient, for patient) they're exempt from the last one which has to do with using cadaveric (dead bodies) tissue or from other sources outside the patient's own body.
2. Why haven't there been any peer reviewed published articles about the swine studies? When can we expect them?
Swanson said they debate this internally because the research done on pigs wasn't approached from an academic point of view, but rather a product optimization one. He said that they had wounds of various sizes and causes and that it would likely just confuse people are not be something that can really be peer reviewed because of their approach. Basically, they used this time to make the product the best it could be by achieving complete regeneration in pigs.
To reiterate he did say that with the pilot study they areapproachingit like a clinical trial with full peer review. He added that they believe since the opportunity exists to actually test on humans the data from the pilot study will be more meaningful.
The product IS being used right now both in the pilot study and in the 15 centers they've released it to thus far. Data will be coming out throughout 2018 both from the pilot study and if providers at the centers choose to write up their results themselves. This will be up to the provider to write, not PolarityTE.
3. Is there an update on the patent application?
Swanson stated that right now they're in the "prosecution" phase of patent approval. He added that from their original application (the lone patent we've seen) it has since been split into 5 patents that they're working on getting the language just right to protect their intellectual property.
He added that they brought up a lawyer full-time from the firm they were working with who is an expert at the patent process. She's extremely excited because she's never been a part of something she feels could be so revolutionary.
4. Is the plan to still bring SkinTE to a wider market release the first quarter of 2018? If not, when will that occur?
I ran out of time before I could ask this directly, but my since from what they were saying is absolutely.
5. Is there an update on the work being done for derivative products based on SkinTE for more cosmetic applications?
Swanson stated that they definitely are moving forward with this and have an R&D arm that is solely devoted to this side of things. Here are the applications he mentioned directly:
a. applications for aesthetics - much smaller scars
b. a derivative applied over a wound bed created by excising a smaller scar. this may or may not need a skin biopsy
c. an injectable paste into existing scars (he could not provide specifics for what the results might be at this time)
d. hair loss
e. figuring out the mechanism that allowed SkinTE to eliminate wound contraction over time
f. off the shelf products - he said this one would be trickiest because the FDA would have more to regulate at this point.
6. Do you believe SkinTE will work on all parts of the body?
Swanson said yes and that it is being used on all parts of the body currently in the centers their product is being offered and in the pilot study.
Lastly, the pilot study is not on clinicaltrials.gov because it doesn't need/have to be done and therefore doesn't need to be on the site.
That's very good news, only one problem: we still don't know when they intend to release the derivative products for treating acne scars.
Since it doesn't have to pass through the FDA I guess it wouldn't take long but a direct answer to that would have been appreciated
8 hours ago, golfpanther said:Alright guys, just got off the phone with Swanson and wanted to make an update while it's fresh.
I didn't record the convo but did make notes while I was talking to him. Here goes:
1. Has the pilot study moved forward and if so, what is the update? If not, what's the cause of the delay and when will it be back on track?
Yes, they have moved forward and the product is in centers right now and being used. They cannot share data with me at this time, but the way it's going to work is that the pilot study will be just like a clinical trial: control wounds, all the same patient, being compared against split-thickness skin grafts etc. It will be heavily vetted and submitted for peer review.
Results from the actual market will be different in the sense that anything that is published will be up to the centers using the product. In Swanson's words, it will be up to the provider to release their findings on its use on their patients.
Their product is regulated by the HTP/C 361 arm of the FDA: human cells, tissues, and cellular and tissue-based products. As such there are four things that must be true to receive approval through this arm (which they already have obtained):
a) minimal manipulation
b.homologous use
c) certain factors cannot be added
d) because it's autologous (from patient, for patient) they're exempt from the last one which has to do with using cadaveric (dead bodies) tissue or from other sources outside the patient's own body.
2. Why haven't there been any peer reviewed published articles about the swine studies? When can we expect them?
Swanson said they debate this internally because the research done on pigs wasn't approached from an academic point of view, but rather a product optimization one. He said that they had wounds of various sizes and causes and that it would likely just confuse people are not be something that can really be peer reviewed because of their approach. Basically, they used this time to make the product the best it could be by achieving complete regeneration in pigs.
To reiterate he did say that with the pilot study they areapproachingit like a clinical trial with full peer review. He added that they believe since the opportunity exists to actually test on humans the data from the pilot study will be more meaningful.
The product IS being used right now both in the pilot study and in the 15 centers they've released it to thus far. Data will be coming out throughout 2018 both from the pilot study and if providers at the centers choose to write up their results themselves. This will be up to the provider to write, not PolarityTE.
3. Is there an update on the patent application?
Swanson stated that right now they're in the "prosecution" phase of patent approval. He added that from their original application (the lone patent we've seen) it has since been split into 5 patents that they're working on getting the language just right to protect their intellectual property.
He added that they brought up a lawyer full-time from the firm they were working with who is an expert at the patent process. She's extremely excited because she's never been a part of something she feels could be so revolutionary.
4. Is the plan to still bring SkinTE to a wider market release the first quarter of 2018? If not, when will that occur?
I ran out of time before I could ask this directly, but my since from what they were saying is absolutely.
5. Is there an update on the work being done for derivative products based on SkinTE for more cosmetic applications?
Swanson stated that they definitely are moving forward with this and have an R&D arm that is solely devoted to this side of things. Here are the applications he mentioned directly:
a. applications for aesthetics - much smaller scars
b. a derivative applied over a wound bed created by excising a smaller scar. this may or may not need a skin biopsy
c. an injectable paste into existing scars (he could not provide specifics for what the results might be at this time)
d. hair loss
e. figuring out the mechanism that allowed SkinTE to eliminate wound contraction over time
f. off the shelf products - he said this one would be trickiest because the FDA would have more to regulate at this point.
6. Do you believe SkinTE will work on all parts of the body?
Swanson said yes and that it is being used on all parts of the body currently in the centers their product is being offered and in the pilot study.
Lastly, the pilot study is not on clinicaltrials.gov because it doesn't need/have to be done and therefore doesn't need to be on the site.
This is great news indeed.
2 hours ago, SimpleMutton said:That's very good news, only one problem: we still don't know when they intend to release the derivative products for treating acne scars.
Since it doesn't have to pass through the FDA I guess it wouldn't take long but a direct answer to that would have been appreciated
I believe by 2020, if the product works we should be in business. Also at that time, I believe Cotsarelis' team would find a way and other competitors like Sunogel will be hitting the market. We have been patient for so long. Another year or two will not hurt.
58 minutes ago, Anonymouz1 said:This is great news indeed. I believe by 2020, if the product works we should be in business. Also at that time, I believe Cotsarelis' team would find a way and other competitors like Sunogel will be hitting the market. We have been patient for so long. Another year or two will not hurt.
Another year or two will hurt. At least for me.
I've been waiting for this for close to 6 years. I can't wait any longer. I need to start my life.
2020 is an arbitrary number.
On their website it's written:
SkinTE is intended to be used by physicians or other appropriate healthcare providers for homologous uses of skin tissues/integument. Patients who have suffered from an event, disease, process or acquired deficit that results in the functional loss or void of skin/integument systems can use SkinTE as an adjunct and/or in place of split-thickness skin grafting, full-thickness grafting, temporizing skin coverage and/or skin substitute products.
Considering cystic acne a disease that causes functional loss or void of skin, I guess it could be used for treating acne scars too.
They said they plan to expand the market release of SkinTE in the first half of 2018, theoretically we could get treated by SkinTE, without waiting for a derivative product, already next year.
It also appears that no matter how extensive your acne scars area is (especially for us that have them in the back), their construct can accomodate all the skin in the body, if needed.
"Constructs are being developed to accommodate different sizes, and should be able to cover the entire body if needed. Our manufacturing process is also being developed to allow for cryopreservation to meet future patient needs"
So, how does this SkinTE work? Biopsy is taken, then some gel is produced from it and it is put on the wound and grows into skin? So those 15 centers are growing tissue from biopsy themselves or are they sending the biopsies to Polarity..? I guess we wont know. But it just seems too quiet if its being used on humans and its working..:(
1 hour ago, eekman said:So, how does this SkinTE work? Biopsy is taken, then some gel is produced from it and it is put on the wound and grows into skin? So those 15 centers are growing tissue from biopsy themselves or are they sending the biopsies to Polarity..? I guess we wont know. But it just seems too quiet if its being used on humans and its working..:(
Well, it take 3 months if I'm not mistaken from the time the construct is applied to when the skin is fully regenerated so it's too early to tell
And practioners may not share the results.
PolarityTE is conducting a human trials though and will share the results
2 hours ago, eekman said:So, how does this SkinTE work? Biopsy is taken, then some gel is produced from it and it is put on the wound and grows into skin? So those 15 centers are growing tissue from biopsy themselves or are they sending the biopsies to Polarity..? I guess we wont know. But it just seems too quiet if its being used on humans and its working..:(
PolarityTE's website goes into a lot of detail about how the process works and Tiano posted a conversation he had with them earlier and they went into more detail if memory serves. Yes, the provider would take a skin biopsy of healthy tissue, which would then be send to a PolarityTE manufacturing lab where it would be processed into SkinTE. Then SkinTE would be sent back to the provider/patient where it would be applied to a wound bed either that was already present or created by excising existing skin tissue. A dressing would then be applied that creates a water barrier.
Look, I get that we all want to know right this second if it works and how quickly we can use it if it does. That's normal human nature. But look at the positive! Swanson could have told me they hadn't started using it and that the pilot study was on indefinite hold pending the patent or something even worse. But he DIDN'T. He stated that it is being used right now both in the pilot study and in the centers that have the product. That is great news.
Also, let's say it is working... would you want to announce that big of a revolutionary shift in wound healing before you were prepared to capitalize on it in the biggest way possible? PolarityTE formed just a little over a year ago and they would in no way be prepared for the demand if they made a huge announcement today.
24 minutes ago, rudy1986 said:
another great news, in a couple month we'll know whether or not SkinTE will be the solution to our problem.
49 minutes ago, rudy1986 said:
News Of The Year.....