Acne.org Products
14 hours ago, Sirius Lee said:The real crux of the matter is whether it will be affordable for those who really need the damn thing.
Yes, this is an issue. Products typically come to market at a price point where most people can't afford it.
However, I do have some hope from what PolarityTE has said about this subject. They seem to understand that there is a balance between profit and actually trying to help people. This could of course all be marketing BS but they've been asked that direct question and have stated they want to keep costs as low as they can so they can help the most people.
PolarityTE: Investors Beware
Summary
PolarityTE™s sole key asset is a patent application that it acquired for a value of $104.7 million.
Common equity holders are exposed to severe potential dilution, given a capital structure that is saddled with convertibles.
PolarityTE has failed to release its full pre-clinical data, and its planned human trials appear delayed.
The entity has been reverse merged several times into a variety of businesses. We believe PolarityTE is the latest in a series of failed story stocks.
We believe the common equity is likely worthless.
https://seekingalpha.com/article/4130500-polarityte-investors-beware
We are short shares of
$COOL and believe the equity is likely worthless0 replies0 retweets0 likesReplyRetweetLike
Common equity holders of
$COOL are exposed to potentially severe dilution via a cap structure that is saddled with convertibles0 replies0 retweets1 likeReplyRetweetLike
1
We believe
$COOL is the latest hype stock in an entity that has been reverse merged into at least 6 different businesses0 replies0 retweets0 likesReplyRetweetLike
$COOL has failed to release its full pre-clinical data and its planned human trials appear delayed0 replies0 retweets0 likesReplyRetweetLike
$COOL's sole key asset is a patent application that it purchased from a resident doctor for a value of $104.7 million
1 hour ago, Sirius Lee said:PolarityTE: Investors Beware
Dec. 7.17 | About: PolarityTE, Inc. (COOL)
Summary
PolarityTE™s sole key asset is a patent application that it acquired for a value of $104.7 million.
Common equity holders are exposed to severe potential dilution, given a capital structure that is saddled with convertibles.
PolarityTE has failed to release its full pre-clinical data, and its planned human trials appear delayed.
The entity has been reverse merged several times into a variety of businesses. We believe PolarityTE is the latest in a series of failed story stocks.
We believe the common equity is likely worthless.
We are short shares of
$COOL and believe the equity is likely worthless0 replies0 retweets0 likesReply
Retweet
Like
Common equity holders of
$COOL are exposed to potentially severe dilution via a cap structure that is saddled with convertibles0 replies0 retweets1 likeReply
Retweet
Like
1
We believe
$COOL is the latest hype stock in an entity that has been reverse merged into at least 6 different businesses0 replies0 retweets0 likesReply
Retweet
Like
$COOL has failed to release its full pre-clinical data and its planned human trials appear delayed0 replies0 retweets0 likesReply
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$COOL's sole key asset is a patent application that it purchased from a resident doctor for a value of $104.7 million
Well that's definitely bad news. Let's not give up hope on this company just yet.
I don't know if this was posted but they are approved for clinical trials. They are expected to release data in 2018.
3 minutes ago, Anonymouz1 said:Well that's definitely bad news. Let's not give up hope on this company just yet.I don't know if this was posted but they are approved for clinical trials. They are expected to release data in 2018.
I posted the article in the private chat some of us are on and while it isn't good news, I think it's wise to keep things in perspective. Honestly, most of that stuff revolves around stock valuation and investment, which doesn't affect or indicate the efficacy of the product one bit. It might work, it might not work, but the article's main thrust is to inform their readers about whether they should invest in the company.
To me, there were 2 salient points raised: 1. Why hasn't there been peer reviewed published papers about the swine tests and 2. Why are there no clinical trials listed on clinicaltrials.gov? However, even with this there are explanations beyond, "The sky is falling and it doesn't work!"
First, it could be that since it's already been approved by the FDA and supposedly in 18 burn centers in the US (and ostensibly being used), Lough and Swanson and PolarityTE have decided it's not necessary to spend the time, money and resources on the trial and instead will just use data from clinics to prove the efficacy of the product. I hope this isn't the case, as I'd like at least a small peer-reviewed pilot trial, but I can see this as a reason.
Second, it could just be delayed and not mean much of anything beyond that.
Third, and this is the most optimistic one, they've already used it on patients and it works. At that point, why do the pilot study? This isn't like other devices or drugs that offer marginal/percentage improvement. If it works like it did in pigs then you'll just have completely regenerated skin.
Fourth, in regards to published papers when it comes to the pigs, I have no idea how long it takes to actually get into a journal and I doubt the author of the article does either. In a quick search for papers on pubmed for studies where Lough was an investigator I found one from April 17th, 2017. That is clearly after he left Johns Hopkins and formed PolarityTE so anecdotally, it seems like these things can take a while.
Lastly, I reached out to PolarityTE after reading the article and basically said that I'm very hopeful for the product but also concerned by the lack of a clinical trial and no published papers and asked for an update. To my surprise, I got a response very quickly. They said we could jump on a call for an update as early as tomorrow or next week. I'm going to do and will keep you all posted. My main questions are:
1. Has the pilot clinical trial begun? If so, do you have any results to share? If not, why and when do you estimate it will happen (if they're still pursuing this)?
2. Why haven't there been any published papers in regards to the tests done on pigs?
3. Has the product been used outside of the pilot study and if so can you share any results?
4. Is the plan to still bring SkinTE to a wide market release in the first half of 2018?
That's bout all I have. Any suggestions are welcome, but reference Tiano's convo with them before to make sure we're getting new questions/information.
14 minutes ago, golfpanther said:I posted the article in the private chat some of us are on and while it isn't good news, I think it's wise to keep things in perspective. Honestly, most of that stuff revolves around stock valuation and investment, which doesn't affect or indicate the efficacy of the product one bit. It might work, it might not work, but the article's main thrust is to inform their readers about whether they should invest in the company.
Research analysts rarely ever make SHORT recommendations. Unless their plan is to screw with the larger investing community, this would be very rash on their part. It's also worth mentioning that most of the rumors that circulate on Wall Street usually pan out as true in the end. As such,I wouldn't be surprised if these analysts have inside info that we are not aware of just yet.
8 hours ago, Sirius Lee said:Research analysts rarely ever make SHORT recommendations. Unless their plan is to screw with the larger investing community, this would be very rash on their part. It's also worth mentioning that most of the rumors that circulate on Wall Street usually pan out as true in the end. As such,I wouldn't be surprised if these analysts have inside info that we are not aware of just yet.
Usually I don't believe most of what these articles say, they are mostly rubbish. Who says wall street rumors end up true? Most of the time they will convince people to sell (So they can buy at lower prices) or ask people to buy (So they can dump their stock at higher prices).
I really doubt they understand what a disruptive technology PolarityTE would be if successful.
I have read a similar article about a month ago, yet I still went ahead and bought PolarityTE shares at $25, now its worth $29 something already (Cross fingers it doesn't go down). Those who bought Polarity at the start for $3 something would have made close to 1000% gains already. I'm not saying that it won't go down, that really depends when the results of the human trials are out and there is more clinics accepting the use of PolarityTE and it being successful. But if that happens, which most likely it will, this stock will skyrocket up much more.
Technology like this usually has to show efficacy to actually make it to market. If Fiona Wood wouldn't have green lit, to some, prematurely, then Recell would not be as available as it is today. SkinTE is clearly opting for the same thing in order to avoid the lengthy, normal FDA process. The real tell whether or not this will produce anything worth while will be the trials. I'm sure it will take a bit to convince these burn centers to use their product though. Grafting is the gold standard, so these surgeons will have to be sure that this will work, that means reviewing the research models and Polarity's data, which we haven't seen yet.
6 hours ago, AI3forever said:Usually I don't believe most of what these articles say, they are mostly rubbish. Who says wall street rumors end up true? Most of the time they will convince people to sell (So they can buy at lower prices) or ask people to buy (So they can dump their stock at higher prices).I really doubt they understand what a disruptive technology PolarityTE would be if successful.
I have read a similar article about a month ago, yet I still went ahead and bought PolarityTE shares at $25, now its worth $29 something already (Cross fingers it doesn't go down). Those who bought Polarity at the start for $3 something would have made close to 1000% gains already. I'm not saying that it won't go down, that really depends when the results of the human trials are out and there is more clinics accepting the use of PolarityTE and it being successful. But if that happens, which most likely it will, this stock will skyrocket up much more.
For the most part, I totally agree. This is a stock evaluation from a research firm that knows that world. I do think they understand the disruptive quality of the product (they talk about that a bit) but most of their analysis comes from the dilution of the stock (a lot of shares out there) and lack of progress from PolarityTE. It's really all speculation and recommendations based on numbers, which is what a firm like that is supposed to do. In terms of PolarityTE, not responding to them, my guess is that they don't want a group like that controlling the flow of information. Any news they give to them will immediately be put into the public sphere and the news, good or bad, could send the stock into chaos. They have a responsibility to their shareholders to protect their investments.
That's why I reached out to PolarityTE. I want to ask them directly if the trials have started, what results there are if so and if not when will they be initiated? I responded back to Dr. Swanson and said I could do the call this morning before 1230pm PST or pretty much anytime next week. I'll keep you all posted and be sure to add on additional questions if any of you have them. I think they responded to me because I'm just a single person and not representing a publication or research group.
This is not relevant to PolarityTE but it more or less explains the regeneration Cotsarelis tries to achieve and it is a paper from a European university for everybody interested to read it. http://basicmed.med.ncku.edu.tw/public/project/1633-1487731977-1.pdf
2 hours ago, Ps93 said:This is not relevant to PolarityTE but it more or less explains the regeneration Cotsarelis tries to achieve and it is a paper from a European university for everybody interested to read it. http://basicmed.med.ncku.edu.tw/public/project/1633-1487731977-1.pdf
Kind of funny, I burned my leg, blister and all, hair grew into it and it faded quite a bit.
5 hours ago, Ps93 said:This is not relevant to PolarityTE but it more or less explains the regeneration Cotsarelis tries to achieve and it is a paper from a European university for everybody interested to read it. http://basicmed.med.ncku.edu.tw/public/project/1633-1487731977-1.pdf
If someone could provide us with some sort of updates on this, he/she would be more than welcomed.
It's been close to a year that this was published but we haven't heard anything from Cotsarelis and his team on how they intend to move forward. They did mention back then that they intended to do clinical trials in the future. They are the closest to have found a workable solution to scarring. Right now, they seem to be the most trustworthy. The only questions I have with their work is what happens with existing scars and how will reprogrammed maturing scar tissue behave in the future. Will this cause skin tumours or other skin disease 10 years from now? Off course, we could speculate that existing scars will be excised and the new developing scar tissue will be reprogrammed to become normal looking as their work suggests.
There are hundreds of people out there who have true disfigurement caused by horrific diseases and accidents. Mostly all humans will get scars wether from minor injuries, surgeries and even moderate to severe acne. I don't see why they are not moving forward especially right now where the younger generation wants to expose their skin most of the time. Cosmetic surgeries are soaring because young people want to look their best and older people don't want to age. Eliminating scarring will just be a benefit to cosmetic surgeons. Then again, many dermatologists might be against it because they gauge significant money out of people for minor improvement of scars.
Also a decade ago, they presented us with stem cells as a solution to scarring but nothing came of this. Scarring was also not a big issue back then for the medical community. It's still considered something as normal today even by most. Nothing to be done, just natural.
3 hours ago, FastMedia said:Kind of funny, I burned my leg, blister and all, hair grew into it and it faded quite a bit.
Cotsarelis was on to something but we haven't heard anything for almost a year. Every now and then, researchers will make a bold discovery and then the media will make a big story out of nothing. How many times, have we seen articles with titles like "Cancer cure found" or "HIV no more". I am hopeful they will continue doing research on this matter and maybe in a few years they will get some funding to test out their findings.
7 hours ago, Anonymouz1 said:Cotsarelis was on to something but we haven't heard anything for almost a year. Every now and then, researchers will make a bold discovery and then the media will make a big story out of nothing. How many times, have we seen articles with titles like "Cancer cure found" or "HIV no more". I am hopeful they will continue doing research on this matter and maybe in a few years they will get some funding to test out their findings.
Eh, cancer isn't something that can be cured, HIV is something they are very close to finding a cure for.
I really do hope that a solution is found as fast as possible with skin regeneration because when the first finds the solution all companies will follow to provide a cheapest solution for skin regeneration.My fear is if either Cotsarelis or skinTE succeed is if the giants like Loreal Sisheido allow them to market their product because imagine a 60 year old who spends thousands of money in botox laser or creams who prefers to give 20 30k or more to erase its wrinkles.I am just questioning and I hope we have a solution very soon.Who knows giants like Loreal since the cooperation with Organovo might transform their business and then offer bioprinted in order to compete the first product to achieve skin regeneration.I really hope we will know soon and see a competition in the near future that is going to be for our benefit
On 12/8/2017 at 4:29 PM, Anonymouz1 said:If someone could provide us with some sort of updates on this, he/she would be more than welcomed.It's been close to a year that this was published but we haven't heard anything from Cotsarelis and his team on how they intend to move forward. They did mention back then that they intended to do clinical trials in the future. They are the closest to have found a workable solution to scarring. Right now, they seem to be the most trustworthy. The only questions I have with their work is what happens with existing scars and how will reprogrammed maturing scar tissue behave in the future. Will this cause skin tumours or other skin disease 10 years from now? Off course, we could speculate that existing scars will be excised and the new developing scar tissue will be reprogrammed to become normal looking as their work suggests.
There are hundreds of people out there who have true disfigurement caused by horrific diseases and accidents. Mostly all humans will get scars wether from minor injuries, surgeries and even moderate to severe acne. I don't see why they are not moving forward especially right now where the younger generation wants to expose their skin most of the time. Cosmetic surgeries are soaring because young people want to look their best and older people don't want to age. Eliminating scarring will just be a benefit to cosmetic surgeons. Then again, many dermatologists might be against it because they gauge significant money out of people for minor improvement of scars.
Also a decade ago, they presented us with stem cells as a solution to scarring but nothing came of this. Scarring was also not a big issue back then for the medical community. It's still considered something as normal today even by most. Nothing to be done, just natural.
Scarring has been a big issue for the medical community for decades. Remember, figuring out how to heal wounds with complete regeneration on the skin is considered a stepping stone toward eliminating scarring and damage across the body (scars from heart attacks, damage to spine etc.). Plus, people have always been bothered by scarring. It may have picked up speed in terms of research lately, owed in large part to work with stem cells, but I remember a research paper being posted here a while back that if memory serves was published just after that end of WW1, undoubtedly in response to the horrors of that war. That's almost 100 years ago.
In terms of Cotsarelis, his type of research is going to take longer than Sunogel or PolarityTE because they are attempting to reprogram one cell type into another (i.e. myofibroblasts into adipocytes). Some of you on here may remember Dr. Paul Martin who believed that by "knocking out" osteopontin you could achieve scar free healing. He was talking about this back in 2009 and scar free healing in general as early as 1997. The thing is, he may well be right, but the medical community is supremely cautious with any method that actively changes the chemistry of the body. I think there's a reasonable amount of caution, but do feel that at times the medical community is too worried about what might come later at the expense of advancement. I also think that if someone is dealing with something life threatening (not us here, but I guess that depends on your point of view) he or she should be able to sign a waiver to get the treatment. This does happen in some cases, but not enough IMO.
I agree that competing forces might try to suppress something like Sunogel or SkinTE because of how disruptive they both could potentially be. However, if either work on just one person it's pretty much game over. The amount of press coverage PolarityTE has gotten just with their studies on pigs is pretty impressive but it would be at least ten fold if a human patient got complete regeneration.
Lastly, I didn't hear from PolarityTE on Friday so I'm going to follow-up with them tomorrow to set up the call. My guess right now is that the patent application is the holdup. As long as that isn't approved they incur huge risk by going to a wide market.
1 hour ago, golfpanther said:Scarring has been a big issue for the medical community for decades. Remember, figuring out how to heal wounds with complete regeneration on the skin is considered a stepping stone toward eliminating scarring and damage across the body (scars from heart attacks, damage to spine etc.). Plus, people have always been bothered by scarring. It may have picked up speed in terms of research lately, owed in large part to work with stem cells, but I remember a research paper being posted here a while back that if memory serves was published just after that end of WW1, undoubtedly in response to the horrors of that war. That's almost 100 years ago.In terms of Cotsarelis, his type of research is going to take longer than Sunogel or PolarityTE because they are attempting to reprogram one cell type into another (i.e. myofibroblasts into adipocytes). Some of you on here may remember Dr. Paul Martin who believed that by "knocking out" osteopontin you could achieve scar free healing. He was talking about this back in 2009 and scar free healing in general as early as 1997. The thing is, he may well be right, but the medical community is supremely cautious with any method that actively changes the chemistry of the body. I think there's a reasonable amount of caution, but do feel that at times the medical community is too worried about what might come later at the expense of advancement. I also think that if someone is dealing with something life threatening (not use here, but I guess that depends on your point of view) he or she should be able to sign a waiver to get the treatment. This does happen in some cases, but not enough IMO.
I agree that competing forces might try to suppress something like Sunogel or SkinTE because of how disruptive they both could potentially be. However, if either work on just one person it's pretty much game over. The amount of press coverage PolarityTE has gotten just with their studies on pigs is pretty impressive but it would be at least ten fold if a patient got complete regeneration.
Lastly, I didn't hear from PolarityTE on Friday so I'm going to follow-up with them tomorrow to set up the call. My guess right now is that the patent application is the holdup. As long as that isn't approved they incur huge risk by going to a wide market.
so will you call them tomorrow?
1 hour ago, damnBOY said:2 hours ago, golfpanther said:Scarring has been a big issue for the medical community for decades. Remember, figuring out how to heal wounds with complete regeneration on the skin is considered a stepping stone toward eliminating scarring and damage across the body (scars from heart attacks, damage to spine etc.). Plus, people have always been bothered by scarring. It may have picked up speed in terms of research lately, owed in large part to work with stem cells, but I remember a research paper being posted here a while back that if memory serves was published just after that end of WW1, undoubtedly in response to the horrors of that war. That's almost 100 years ago.In terms of Cotsarelis, his type of research is going to take longer than Sunogel or PolarityTE because they are attempting to reprogram one cell type into another (i.e. myofibroblasts into adipocytes). Some of you on here may remember Dr. Paul Martin who believed that by "knocking out" osteopontin you could achieve scar free healing. He was talking about this back in 2009 and scar free healing in general as early as 1997. The thing is, he may well be right, but the medical community is supremely cautious with any method that actively changes the chemistry of the body. I think there's a reasonable amount of caution, but do feel that at times the medical community is too worried about what might come later at the expense of advancement. I also think that if someone is dealing with something life threatening (not use here, but I guess that depends on your point of view) he or she should be able to sign a waiver to get the treatment. This does happen in some cases, but not enough IMO.
I agree that competing forces might try to suppress something like Sunogel or SkinTE because of how disruptive they both could potentially be. However, if either work on just one person it's pretty much game over. The amount of press coverage PolarityTE has gotten just with their studies on pigs is pretty impressive but it would be at least ten fold if a patient got complete regeneration.
Lastly, I didn't hear from PolarityTE on Friday so I'm going to follow-up with them tomorrow to set up the call. My guess right now is that the patent application is the holdup. As long as that isn't approved they incur huge risk by going to a wide market.
so will you call them tomorrow?
I will try to get a call with them as early as tomorrow but it depends on their availability. I'm going to reach out again to set that up.
55 minutes ago, golfpanther said:Scarring has been a big issue for the medical community for decades. Remember, figuring out how to heal wounds with complete regeneration on the skin is considered a stepping stone toward eliminating scarring and damage across the body (scars from heart attacks, damage to spine etc.). Plus, people have always been bothered by scarring. It may have picked up speed in terms of research lately, owed in large part to work with stem cells, but I remember a research paper being posted here a while back that if memory serves was published just after that end of WW1, undoubtedly in response to the horrors of that war. That's almost 100 years ago.In terms of Cotsarelis, his type of research is going to take longer than Sunogel or PolarityTE because they are attempting to reprogram one cell type into another (i.e. myofibroblasts into adipocytes). Some of you on here may remember Dr. Paul Martin who believed that by "knocking out" osteopontin you could achieve scar free healing. He was talking about this back in 2009 and scar free healing in general as early as 1997. The thing is, he may well be right, but the medical community is supremely cautious with any method that actively changes the chemistry of the body. I think there's a reasonable amount of caution, but do feel that at times the medical community is too worried about what might come later at the expense of advancement. I also think that if someone is dealing with something life threatening (not use here, but I guess that depends on your point of view) he or she should be able to sign a waiver to get the treatment. This does happen in some cases, but not enough IMO.
I agree that competing forces might try to suppress something like Sunogel or SkinTE because of how disruptive they both could potentially be. However, if either work on just one person it's pretty much game over. The amount of press coverage PolarityTE has gotten just with their studies on pigs is pretty impressive but it would be at least ten fold if a patient got complete regeneration.
Lastly, I didn't hear from PolarityTE on Friday so I'm going to follow-up with them tomorrow to set up the call. My guess right now is that the patent application is the holdup. As long as that isn't approved they incur huge risk by going to a wide market.
Scarring was always an issue but people learned quickly to accept it as the normal outcome of healing and show scars as a badge of honor. However, I believe right now the time has come to find a solution. Humanity has evolved in a such a way that using our minds we can find an effective way to regenerate our biggest organ: the skin.
Plastic surgery or cosmetic surgery (whatever you may wish to call it) emerged following WW1. Many surgeons and doctors, at the time, were called upon to find ways to deal with all the horrific injuries sustained by all those men in combat. Disfigured soldiers had to be re-insurted into the community and lead normal lives following the end of the war.
Those surgeons are the pioneers of an emerging field whose initial purpose was to eliminate scarring and to find ways to regenerate lost tissues. They did their best, at the time, to give many men a somewhat normal facial appearance and a second chance for society to accept them with their disfigurement.
During WW2, severe injuries and other pathogens (consequences of the war) lead to more disfigurement. The medical community was heavily relied upon once more to find solutions to treat millions of people. A lot of research and experimentation was done during this time providing modern medicine with a great opportunity to find better and effective treatments. However at some point, many people knew there was money to be made. The field itself lost its initial purpose. Thus, cosmetic surgery was born. From that point on, themedical community decided to just deal with the life threatening aspect of an injury or disease and the cosmetic outcome not so much.
As an example, you are told to see a cosmetic surgeon or dermatologist if you want improvement to your scarring. That being sad, many current surgeons or doctors do their best to minimize scarring following a medical procedure, skin disease or major injury.
Eventually, the cosmetic field itself became a money making industry as more and more people wanted to look their best. Many jumped on to the occasion and either became rich (cosmeticians/plastics/dermatologists ). Others dished out huge sums to transform their look and correct minor flaws which for the average person are not flaws at all.
As you know, if it is not life threatening, cosmetic surgery is seldom covered by healthcare plans. Acne scarring revision is only covered by one western country which I believe is Australia. While it took years before dental hygiene and tooth decay were covered by some healthcare plans.
In the end, scarring itself was never addressed and to this day no existing treatment is effective to completely eliminate it. The medical community has always considered it part of the normal healing phase. After all, our bodies don't want to regenerate following injury but rather scar. The scar seals the wound with some under/over-expressed collagen over time and we call it a day. The same goes for the rest of our organs.
Restorative medicine has been developing for some time now as an alternative to cosmetic surgery and most importantly modern medicine. We need to realize that more and more people are becoming self conscious about their scars as technology progresses and beauty perceptions keep changing. The issue with cosmetic surgery is it's cost and it doesn't address scarring or regeneration. Mind you, skin or body improvements are possible.
With the discovery of stem cells and other scientific breakthroughs, regenerative medicine aims for complete regeneration as its name suggests. Unfortunately, it's in the initial phases and you have a lot of charlatans out there looking to make a buck just like in the cosmetic field. We need to be vigilant and not fall victims to false claims.
Although, regenerative medicine is a possible alternative to modern treatments or techniques, it lacks a bit of funding and most in the medical community discredit it because they believe there is no money to be made. As an example, eliminating scarring would only require one treatment compared to the several costly treatments existing today which aim for improvement. Furthermore, regenerating an arm will no longer require simple or enhanced prosthetics. Repairing the pancreas with stem cells will also drive companies out of business especially big pharma marketing injectable insulin.
The perception of the established medical community is also pretty clear. If it is not life threatening, then why bother. You need to understand that people can live somewhat normal lives with scarring or lost limbs. Scarring itself is mostly a cosmetic issue to begin with. Sure burn scars do cause complications but acne scarring does not limit someone's life in anyway spare some stares from other people. Some would say this causes depression to the affected individual but modern medicine would just give you a "magic pill" and tell you "off you go". Same thing happens with current acne treatments. Finding a cure for acne and getting to the root cause of depression is seldom discussed.
It all comes down to big bucks. This is why I believe we are years away from establishing a worldwide regenerative medical practice. The biggest fear also with all of this is that if SkinTE or Sunogel succeed, the cosmetic field will jump through hoops to take them out through a takeover or finding a similar technology. At the end of the day, the technology itself to remove scars will be affordable to the few. It will be years before a common mortal (us, the not so fortunate) will be able to afford complete removal of our scars.
1 hour ago, Anonymouz1 said:Scarring was always an issue but people learned quickly to accept it as the normal outcome of healing and show scars as a badge of honor. However, I believe right now the time has come to find a solution. Humanity has evolved in a such a way that using our minds we can find an effective way to regenerate our biggest organ: the skin.Plastic surgery or cosmetic surgery (whatever you may wish to call it) emerged following WW1. Many surgeons and doctors, at the time, were called upon to find ways to deal with all the horrific injuries sustained by all those men in combat. Disfigured soldiers had to be re-insurted into the community and lead normal lives following the end of the war.
Those surgeons are the pioneers of an emerging field whose initial purpose was to eliminate scarring and to find ways to regenerate lost tissues. They did their best, at the time, to give many men a somewhat normal facial appearance and a second chance for society to accept them with their disfigurement.
During WW2, severe injuries and other pathogens (consequences of the war) lead to more disfigurement. The medical community was heavily relied upon once more to find solutions to treat millions of people. A lot of research and experimentation was done during this time providing modern medicine with a great opportunity to find better and effective treatments. However at some point, many people knew there was money to be made. The field itself lost its initial purpose. Thus, cosmetic surgery was born. From that point on, themedical community decided to just deal with the life threatening aspect of an injury or disease and the cosmetic outcome not so much.
As an example, you are told to see a cosmetic surgeon or dermatologist if you want improvement to your scarring. That being sad, many current surgeons or doctors do their best to minimize scarring following a medical procedure, skin disease or major injury.
Eventually, the cosmetic field itself became a money making industry as more and more people wanted to look their best. Many jumped on to the occasion and either became rich (cosmeticians/plastics/dermatologists ). Others dished out huge sums to transform their look and correct minor flaws which for the average person are not flaws at all.
As you know, if it is not life threatening, cosmetic surgery is seldom covered by healthcare plans. Acne scarring revision is only covered by one western country which I believe is Australia. While it took years before dental hygiene and tooth decay were covered by some healthcare plans.
In the end, scarring itself was never addressed and to this day no existing treatment is effective to completely eliminate it. The medical community has always considered it part of the normal healing phase. After all, our bodies don't want to regenerate following injury but rather scar. The scar seals the wound with some under/over-expressed collagen over time and we call it a day. The same goes for the rest of our organs.
Restorative medicine has been developing for some time now as an alternative to cosmetic surgery and most importantly modern medicine. We need to realize that more and more people are becoming self conscious about their scars as technology progresses and beauty perceptions keep changing. The issue with cosmetic surgery is it's cost and it doesn't address scarring or regeneration. Mind you, skin or body improvements are possible.
With the discovery of stem cells and other scientific breakthroughs, regenerative medicine aims for complete regeneration as its name suggests. Unfortunately, it's in the initial phases and you have a lot of charlatans out there looking to make a buck just like in the cosmetic field. We need to be vigilant and not fall victims to false claims.
Although, regenerative medicine is a possible alternative to modern treatments or techniques, it lacks a bit of funding and most in the medical community discredit it because they believe there is no money to be made. As an example, eliminating scarring would only require one treatment compared to the several costly treatments existing today which aim for improvement. Furthermore, regenerating an arm will no longer require simple or enhanced prosthetics. Repairing the pancreas with stem cells will also drive companies out of business especially big pharma marketing injectable insulin.
The perception of the established medical community is also pretty clear. If it is not life threatening, then why bother. You need to understand that people can live somewhat normal lives with scarring or lost limbs. Scarring itself is mostly a cosmetic issue to begin with. Sure burn scars do cause complications but acne scarring does not limit someone's life in anyway spare some stares from other people. Some would say this causes depression to the affected individual but modern medicine would just give you a "magic pill" and tell you "off you go". Same thing happens with current acne treatments. Finding a cure for acne and getting to the root cause of depression is seldom discussed.
It all comes down to big bucks. This is why I believe we are years away from establishing a worldwide regenerative medical practice. The biggest fear also with all of this is that if SkinTE or Sunogel succeed, the cosmetic field will jump through hoops to take them out through a takeover or finding a similar technology. At the end of the day, the technology itself to remove scars will be affordable to the few. It will be years before a common mortal (us, the not so fortunate) will be able to afford complete removal of our scars.
I agree with you except the part that the treatment will not be affordable.I am sure it will come at a very heavy price propably 50k or something similar but i think most of us would try to find that amount of musoney to transform their lives because it will be an investment to ourselves.At the end of the day why would it be affordable only for millionaires as the good profits will come from the average class and I hope they will sell it for
One question that I also have is isn,t there any billionaire that had that issue with acne scars or skin regeneration so as to look forever young that could financially back up for a research on skin regeneration so as to make it profitable and make billions out of that or do you think that with multiple treatments of hundres thousands of dollars this issue could have been eliminates for the rich people of this world?
Even if it costs 50k I'd drop them in a heartbeat.
I think if people have doubts whether to spend a certain amount of money or not is because their scars aren't that bad and don't impact their lives completely, like mine do.
I'm pretty much not living because of my scars and I do get upset when I see people posting pics on here claiming they have disfiguring scars and then they have just a bunch of shallow spots.....
When it comes to spending money it's all about priority and trade off (what you have to give up in buying/getting to spend the money on the scars treatment) . If you don't want to spend money on it because you prioritize other things (car, travels, tech, clothes, house, whatever) then your scars probably are just a minor problem and more of an annoyance than a life destroying, suicide worth condition.
My scars are so bad that I can't even post here
If scarless healing is found in 10 years time.....i would consider that pretty lucky....i have had a lot of derms and plastic surgeons say 50 to maybe not ever.I know people with acne scars including me would love scarless healing but all these so called treatments end up being flops.Seeing is believing.....so if you have proof something words by all means post it.
4 minutes ago, SimpleMutton said:Even if it costs 50k I'd drop them in a heartbeat.
I think if people have doubts whether to spend a certain amount of money or not is because their scars aren't that bad and don't impact their lives completely, like mine do.
I'm pretty much not living because of my scars and I do get upset when I see people posting pics on here claiming they have disfiguring scars and then they have just a bunch of shallow spots.....When it comes to spending money it's all about priority and trade off (what you have to give up in buying/getting to spend the money on the scars treatment) . If you don't want to spend money on it because you prioritize other things (car, travels, tech, clothes, house, whatever) then your scars probably are just a minor problem and more of an annoyance than a life destroying, suicide worth condition.
My scars are so bad that I can't even post here
Dude.....i don't think it would cost 50k even if someone came up with scarless healing as it would have many uses...not just acne scarring.
24 minutes ago, nikkigirl said:If scarless healing is found in 10 years time.....i would consider that pretty lucky....i have had a lot of derms and plastic surgeons say 50 to maybe not ever.I know people with acne scars including me would love scarless healing but all these so called treatments end up being flops.Seeing is believing.....so if you have proof something words by all means post it.
Dude.....i don't think it would cost 50k even if someone came up with scarless healing as it would have many uses...not just acne scarring.
Dermatologists and many plastic surgeons, for obvious reasons, don't want scarless healing to be a reality, they legally steal so much money with useless treatments that offer very limited results like lasers (all kind), fillers, peelings, TCA cross, needling ecc.
If someone come up with a scarless healing product their profits would plummet....
If they could they would ban scarless healing products from existence and all the research associated with it.
They only care about how much money they can get and they couldn't give a sh*t if someone life is destroyed because of acne scars.
It's also worth saying that often we know more than many dermatologist know about future treatments. I wonder how many dermatologists knows about SkinTE and Sunogel, I'd say less than 1%.
As for the price, I think it's also depends about how large is the area to treat and how quick you want to get treated....if you don't want to wait it's gonna be more expensive
Anyway I think SkinTE will be quite expensive
By the way, in 10 years we will probably have a vaccine for acne (now in development phase) that will probably eradicate this terrible disease from existence.
Scarless healing is a reality right now, PolarityTE has the technology, the skills and the potential to cure us already now. Let's wait for the first pics on human trials to show up but I'm pretty confident. The management of the company (that of course have insider infos) seems very confident and optimistic so I don't understand why we should be negative. Of course someone can say "they have to say certain things to get funds ecc" but as of now all their timelines proved to be correct and accurate.
57 minutes ago, SimpleMutton said:Even if it costs 50k I'd drop them in a heartbeat.
I think if people have doubts whether to spend a certain amount of money or not is because their scars aren't that bad and don't impact their lives completely, like mine do.
I'm pretty much not living because of my scars and I do get upset when I see people posting pics on here claiming they have disfiguring scars and then they have just a bunch of shallow spots.....When it comes to spending money it's all about priority and trade off (what you have to give up in buying/getting to spend the money on the scars treatment) . If you don't want to spend money on it because you prioritize other things (car, travels, tech, clothes, house, whatever) then your scars probably are just a minor problem and more of an annoyance than a life destroying, suicide worth condition.
My scars are so bad that I can't even post here
I have lots of scars. My knees have a few from scrapes as a kid. I acquired about a dozen more from a single car accident. I also have a couple more on my body from several other incidents. But the cystic acne I developped as a teenager wrecked my skin. I still suffer from this condition well into my thirties.
My face has many indentations but they are shallow. I get all upset when sunlight hits my face. To me they look bad but I have seen cases far worse than mine. I am grateful, the damage was not severe. I can't imagine what you go through.
My back/shoulders are wrecked. They are covered with small white raised scars from all that cystic acne throughout the years. I managed to keep it at bay with minor lifestyle changes but now I have developed a horrible case of folliculitis. You just can't win with these little monsters. Also I got multiple staph infections in the past which left me with scars too as well as measles and chicken pox. I also get eczema time to time and psoriasis. Talk about striking out in the skin department. Also my skin pores are about 3 mm large which I believe is the main cause of my skin issues.
As a teenager, my parents took me to a few derms who gave me some antibiotics and they did nothing for me. My mom was against Accutane so I never took it. The pain I got from sleeping on them was enormous. Also major joint pain. My self confidence took a plunge because I would avoid going to pools or beaches. Years past and now I wonder how I can get back those years. My chest remained clear. I never got one zit there. Makes you wonder. I don't trust derms. All the ones I went to would rush you in and rush you out. They don't care about us even though they could alleviate our symptoms. They rather get money from sixty year old women injecting botox.
If some scientist would approach me and promise me to completely regenerate the skin, it would be a blessing but I am not hopeful it will happen
13 minutes ago, Anonymouz1 said:I have lots of scars. My knees have a few from scrapes as a kid. I acquired about a dozen more from a single car accident. I also have a couple more on my body from several other incidents. But the cystic acne I developped as a teenager wrecked my skin. I still suffer from this condition well into my thirties.My face has many indentations but they are shallow. I get all upset when sunlight hits my face. To me they look bad in the car mirror but I have seen cases far worse than mine. I am grateful, the damage was not severe. I can't imagine what you go through seeing your face damaged by these little monsters.
My back/shoulders are wrecked. They are covered with small white raised scars from all that cystic acne throughout the years. I managed to keep it under control with minor lifestyle changes but now I hhs
Yes, I think many of us on this topic have bad scars, even though many that post their pics on the forum often have shallow, very limited scars damage that make me wonder why they even care about that.
I had (and still have) cystic acne since I was 12yo. I'm in my late 20's now.....I had 3 Accutane treatments at very high dosages for 6 months each and never got cured of cystic acne, it only disappears for a couple of months after every course but then it returns
My entire back is absolutely devastated to the point it's incredibly hard even to see normal, non scarred, non hyperpigmentated (or hypopigmentated) skin. My shoulders and upper arms are full of white raised scars (I think like yours).
My chest still have bad cystic acne and in that area it causes me hypopigmentation when it heals.
Even in my belly and legs I have some cystic acne and scars (not as bad as in other parts).
My face of course also have cystic acne and bad acne scars all over.
A product like SkinTE (or another scarless healing one) would be a miracle for me and would pay every price to get it given my condition
If I can ask you, what lifestyle changes did you implement that improved your condition?