47 minutes ago, Tano1 said:This is a response to mjg713 because it won't let me reply to your comment.
The truth is not Sunny nor anyone in here except for PolarityTE can answer that.
The margin in that image on their site could be the end result after regeneration or it could've been made by them. What we CAN analyze from that image is that it is under magnification. How zoomed it is; that we don't know either, but it is somewhat close we can conclude.
I'm going to give you my personal perspective.I want you to do a quick experiment. I want you to expose your entire shoulder so that you can see it so it might require you to take your shirt off. Next, put it under any light whether it's from the sun or your house just as long as you can see it clearly. Now look closely at it and you should see multiple little lines intersecting each other forming shapes; It is similar to a basket weave pattern. If you can't quite make them out then put 2 fingers together and push the skin around on your shoulder lightly and they should become more visible.
Now go back to that image on PolarityTE's site and look at that image with the margin again. Do you see the hair follicles in the image below? Well look close and you can tell that the margin is slightly thinner than the follicles. The margin also has a resembling skin tone to the basket weave pattern we have as well. The lines are a little shaded in our pattern and it looks about the same in the margin. That is my perspective of the margin.
The only sure fire way to know if that is an end result or an intentionally made mark to distinguish both skin areas is by seeing the results when they're available.
It's interesting to see that by the margin image they put "Full Defect Epithelialization and Scarless Healing." I wonder how they think those terms are being defined as.
In my opinion, there will be no margin. otherwise one would have seen a margin on the image of the pig on their site. In a few months we shall have the answer to all our questions.
5 hours ago, slave of jesus said:In my opinion, there will be no margin. otherwise one would have seen a margin on the image of the pig on their site. In a few months we shall have the answer to all our questions.
They labeled it as margin on there. I do agree that I see no indication of a mark in the other pictures where they show the healing of the burn wound especially the day 10 one with LGR. The perspective I wanted to show him though was that there could be some type of margin left as an end result, but maybe it just isn't visible to the naked eye. Their results ofc will say it all.
just to show you ow far away any of the typical modes to for scars --this woman had deep dermabrasion and had tried many lasers before. Shes not left with more fucked up problems.
1 hour ago, Rez77 said:just to show you ow far away any of the typical modes to for scars --this woman had deep dermabrasion and had tried many lasers before. Shes not left with more fucked up problems.
She has depressed scars (rolling scars and deep boxscars). Dermabrasion is not the option. It's previous half century treatment and completly waste of money for her situation. Compairing to lasers it's only "split" the epidermis and not even close come to the lower derma layers, where the scars are. And her 12 lasers procedures, I think she is about her 35-40s, so not all lasers are the same...Fraxel is outdated and not a good solution for the acne scars, Polamar lasers is sh*t and this were the most common options for her time. After 2012 we received not only much better and new generations of lasers, but doctors start to combine it: subcision+Profractional, ablative + non-ablative lasers, RF+PRP, etc. And results have become much better. And lasers are much more safer, than dermabrasion, it's very sad that shi**y doctors who don't know the modern treatments still suggest so traumatic procedure that completly useless for any kind of depressed scars. But even now if she'll find a good doctor she could get abot 60% of improvements obviously. Probably, If the cell therapy will receive a boost, it could give about 20% of improvement in plus, We can see on PubMed were published some articles about stem cell injections for severe acne scars, results are good, but still not the 100% ofc. So Polarity is the best bet for now.
You all need to realize that it takes longer than a few weeks for the skin to remodel. Even after re epithelialization the skin will keep healing. I've burned my leg but hair grew into the scar, it was very hyperpigmented for months, even years but slowly blended into the surrounding skin. Just the fact that SkinTe allows the dermis to regenerate means that the scars should fade over time.
29 minutes ago, 34erer34 said:You all need to realize that it takes longer than a few weeks for the skin to remodel. Even after re epithelialization the skin will keep healing. I've burned my leg but hair grew into the scar, it was very hyperpigmented for months, even years but slowly blended into the surrounding skin. Just the fact that SkinTe allows the dermis to regenerate means that the scars should fade over time.
You make reference at margin on the photo? In my opinion, the margin will eventually disappear, because skinte acts on fabrics cicatrielle. We shall have morenews soon
5 hours ago, GeneTrouble said:7 hours ago, Rez77 said:just to show you ow far away any of the typical modes to for scars --this woman had deep dermabrasion and had tried many lasers before. Shes not left with more fucked up problems.
She has depressed scars (rolling scars and deep boxscars). Dermabrasion is not the option. It's previous half century treatment and completly waste of money for her situation. Compairing to lasers it's only "split" the epidermis and not even close come to the lower derma layers, where the scars are. And her 12 lasers procedures, I think she is about her 35-40s, so not all lasers are the same...Fraxel is outdated and not a good solution for the acne scars, Polamar lasers is sh*t and this were the most common options for her time. After 2012 we received not only much better and new generations of lasers, but doctors start to combine it: subcision+Profractional, ablative + non-ablative lasers, RF+PRP, etc. And results have become much better. And lasers are much more safer, than dermabrasion, it's very sad that shi**y doctors who don't know the modern treatments still suggest so traumatic procedure that completly useless for any kind of depressed scars. But even now if she'll find a good doctor she could get abot 60% of improvements obviously. Probably, If the cell therapy will receive a boost, it could give about 20% of improvement in plus, We can see on PubMed were published some articles about stem cell injections for severe acne scars, results are good, but still not the 100% ofc. So Polarity is the best bet for now.
Give me a friggin break, she had all the latest lasers done. Dermabrasion is still the standard of care for this type of treatment. I've seen every result from the combined PRP, subcision, laser blah blah fat etc. approach. EVERYTHING. And if the lighting is the same you won't see diddly squat difference. 100 percent guaranteed. Only where they subtly crop and use diff. lighting will everything be better.
I've seen people wait years thinking their skin would "remodel" from some skin gun using a biopsy of stem cells like renovo plus prp plus laser plus blah blah and at best I saw NO IMPROVEMENT in acne scars. So bugger all this waiting for skin to remodel over years.
And how exactly will the skinTE work???? You're gonna have your skin dermabraded or lasered or whatever to the level of the deep rolling scars and be a skinless anatomical model and then skinTE will fix your skin in months, years? Give me a break. Its the holy grail of the fountain of youth. It didn't happen for Ponce de leon and it ain't happening for us.
1 hour ago, Rez77 said:Give me a friggin break, she had all the latest lasers done. Dermabrasion is still the standard of care for this type of treatment. I've seen every result from the combined PRP, subcision, laser blah blah fat etc. approach. EVERYTHING. And if the lighting is the same you won't see diddly squat difference. 100 percent guaranteed. Only where they subtly crop and use diff. lighting will everything be better.
I've seen people wait years thinking their skin would "remodel" from some skin gun using a biopsy of stem cells like renovo plus prp plus laser plus blah blah and at best I saw NO IMPROVEMENT in acne scars. So bugger all this waiting for skin to remodel over years.
And how exactly will the skinTE work???? You're gonna have your skin dermabraded or lasered or whatever to the level of the deep rolling scars and be a skinless anatomical model and then skinTE will fix your skin in months, years? Give me a break. Its the holy grail of the fountain of youth. It didn't happen for Ponce de leon and it ain't happening for us.
Na SkinTE extracts your own healthy skin cells and they'll add their chosen biological growth factors with their tech and utilize LGR as well. It takes less than 24 hours and then it's re-injected back into the skin through wounding. Full regeneration takes around 3 months but their site pictures show massive improvement within the 1st 10 days.
If you're having to ask about their method then I'll assume you don't research either. Just read what the info on their site and patent as well as check out the images of their results on swine. Some of us have provided links a page or two back.
Did you just suggest a presently developed technology isn't going to work simply because a mythical fountain didn't work for a guy from a spanish fable more than 500 years ago? Well they sure fooled me with their mythical results from their mythical healing.
By what means (aside from mythical stories) do you decide to claim SkinTE won't work if you don't even know what it is or how it's done?
3 hours ago, Rez77 said:Give me a friggin break, she had all the latest lasers done. Dermabrasion is still the standard of care for this type of treatment. I've seen every result from the combined PRP, subcision, laser blah blah fat etc. approach. EVERYTHING. And if the lighting is the same you won't see diddly squat difference. 100 percent guaranteed. Only where they subtly crop and use diff. lighting will everything be better.
I've seen people wait years thinking their skin would "remodel" from some skin gun using a biopsy of stem cells like renovo plus prp plus laser plus blah blah and at best I saw NO IMPROVEMENT in acne scars. So bugger all this waiting for skin to remodel over years.
And how exactly will the skinTE work???? You're gonna have your skin dermabraded or lasered or whatever to the level of the deep rolling scars and be a skinless anatomical model and then skinTE will fix your skin in months, years? Give me a break. Its the holy grail of the fountain of youth. It didn't happen for Ponce de leon and it ain't happening for us.
I cant belive that mods let you keep on posting in this thread. You are ignorant and very annoying. Werent you the one who said you would leave this thread?
lol I don't mind to spend 50.000$ to erase all my stretch marks from my body, every single stretch mark, I will take the airplane, I will go to USA to treat my stretch marks .....<333333 come on polarityTE do it. I am sure skinTE will work ..... and 4-5 years from now it will be ready for cosmetics and scar revisions....they made it in swine models why not in humans......these f*cking stretch marks almost led me to anorexia when I was a teenager and destroy all my teen years.....and the crazy thing... I was skinny when I created them,stretch marks cr*pppppp
7 hours ago, Rez77 said:Give me a friggin break, she had all the latest lasers done. Dermabrasion is still the standard of care for this type of treatment. I've seen every result from the combined PRP, subcision, laser blah blah fat etc. approach. EVERYTHING. And if the lighting is the same you won't see diddly squat difference. 100 percent guaranteed. Only where they subtly crop and use diff. lighting will everything be better.
I've seen people wait years thinking their skin would "remodel" from some skin gun using a biopsy of stem cells like renovo plus prp plus laser plus blah blah and at best I saw NO IMPROVEMENT in acne scars. So bugger all this waiting for skin to remodel over years.
And how exactly will the skinTE work???? You're gonna have your skin dermabraded or lasered or whatever to the level of the deep rolling scars and be a skinless anatomical model and then skinTE will fix your skin in months, years? Give me a break. Its the holy grail of the fountain of youth. It didn't happen for Ponce de leon and it ain't happening for us.
Dermabrasion is a standart of care? Really? In what country? InZimbabwe? Probabply, yes. Even in my country everyqualified doctor will say it is outdated. All "good" results from it could be achieved just because ofstretched skin and its about 1 year to rollback. And what about "lastest lasers"? I didn't see anything about the model of that lasers from her topic. We can see on realself how doctors in 2007-2014 promised "huge improvement" from Fraxel models for acne scars and now almost all of them say it's outdated and other devices could bring much better improvements alone. RF INFINI, CO2CORE, Joule Sciton is one of the latest, but even they are becoming an old one for now. Nevertheless, even the future generations of lasers will not bring the desirable result (alone). It doesn't matter how deep they could "wound" a skin bcuz of it can't help to regenerate skin appendages. But from 2013 on PubMed were published some results of mesenchymal stem cell injections (you can find some photo on this site or search the darknet or buy the article). And there only 1 injection gave about 40-50% improvement of severe acne(~8 lasers procedures, but it depends on person ofc). And I didn't say anything about "skinless" treatment of SkinTE. In previous topic I just supposed so, bcuz ofat first glance it sounds miracle how simple injection could cut thefibroticstrands and help the skin to recover it'sthicknessexactly as in normal skin. But stem cell trials prove it (btw this therapy have a huge grow factor potential and trick is that "wound" recovery faster and in better quality). And even the funny fact that every of us have grown from the tiny embryo to what we can see now says that nature is a wounderfull thing that humanity study for so many years andstep by step "break the codes". I just hope PolarityTE or other company could break the scarless human skin code soon. And btw I don't really care even IF the only way will be completely skin removing and than applying SkinTE. There will be a procedure of a head transplantation at the end of this year, comparing to this I guess "skinless" treatment sounds not so frightfull.
P.S. And I don't know about your experience, but personally I see an improvement from my combination of lasers treatment I had been done. I know the trick with the ligh, but I see that my skin skin became smoother and I haven't back in my starting point after years of such treatment. AS i said before, it's about 60% of improvement.
18 hours ago, Rez77 said:Oh yeah and just a note of advice....don't get all wet in the panties till you hear the result of human trials and even then that its available at a doctor's office clinically.
lol, it'll be available at a few plastic surgeons offices, they will have to prove its efficacy over skin grafting which is still the gold standard for burns, that's why I'm not so cynical about it working, I'm more cynical about when any of us will actually be able to use it
If I were SkinTe I would lock in on scar revisions more than fresh burn wounds
This thread is the same pathetic shit as a couple years ago. 70% comments about "i hope this and i hope that", 25% "i am so pissed off, this will never work" and 5% actual useful information.
I give you a tip: No wishing, no crying and no spamming in the world will make this happen faster.
22 hours ago, Anish004 said:22 hours ago, Tano1 said:Won't be seeing me in 2030. I'll have my scars erased before then.
how ?
lol.. "how"
a new article on polarity,it iswritten " Operating out of University of Utah Research Park, PolarityTE is developing has product called SkinTE. The company says its technology will be able to regenerate has burn of survivor severe burn wounds with minimal scarring healthy skin tissue so that it can be used to heal. The company expects to test its process one humans later this year, executive said in June. The regenerated skin also will develop to hate follicles, Lough said." http://www.sltrib.com/news/business/2017/08/14/execs-with-utah-based-polarityte-ring-nasdaqs-closing-bell/
I thought that skintecan regeneratethe skin (scarfree Healing) but in the article it is written " minimal scarring "further they say that the tests on humans should begun in June
3 hours ago, slave of jesus said:a new article which writes " Operating out of University of Utah Research Park, PolarityTE is developing has product called SkinTE. The company says its technology will be able to regenerate has burn of survivor severe burn wounds with minimal scarring healthy skin tissue so that it can be used to heal. The company expects to test its process one humans later this year, executive said in June. The regenerated skin also will develop to hate follicles, Lough said." http://www.sltrib.com/news/business/2017/08/14/execs-with-utah-based-polarityte-ring-nasdaqs-closing-bell/
I thought that skintecan regeneratethe skin (scarfree Healing) but in the article it is written " minimal scarring "further they say that the tests on humans should begun in June
Don't take it seriously.Journalists can distort the meaning. If this would be a scientific paper the we can be sure it's true. PolarityTE states some intersting things in that article, sush as
"The regenerated skin also will develop hair follicles, Lough said",Skin regeneration will propel us into numerous other arenas, the company website said, including bone, muscle, fascia, cartilage and nerve.
We can interpret them as scar-free healing (or scar-less which can mean the same in some context).
20 minutes ago, JackDoe said:Don't take it seriously.Journalists can distort the meaning. If this would be a scientific paper the we can be sure it's true. PolarityTE states some intersting things in that article, sush as
"The regenerated skin also will develop hair follicles, Lough said",Skin regeneration will propel us into numerous other arenas, the company website said, including bone, muscle, fascia, cartilage and nerve.We can interpret them as scar-free healing (or scar-less which can mean the same in some context).
I agree with you, but polarity published this article on their site. They approve all which is written in the article ?
8 hours ago, slave of jesus said:a new article on polarity,it iswritten " Operating out of University of Utah Research Park, PolarityTE is developing has product called SkinTE. The company says its technology will be able to regenerate has burn of survivor severe burn wounds with minimal scarring healthy skin tissue so that it can be used to heal. The company expects to test its process one humans later this year, executive said in June. The regenerated skin also will develop to hate follicles, Lough said." http://www.sltrib.com/news/business/2017/08/14/execs-with-utah-based-polarityte-ring-nasdaqs-closing-bell/
I thought that skintecan regeneratethe skin (scarfree Healing) but in the article it is written " minimal scarring "further they say that the tests on humans should begun in June
As I said before that the margin could be an end result of their regenerated skin. If it is, then that margin wouldn't heal on its own because it's slightly pitted and we all know how difficult it is to deal with pitting. Might be very small and un-noticeable though.
Sprays and Disinfectants that release bacteria killing agents usually have something like this written on the label: "kills 99.9% bacteria." Why wouldn't they just put 100%? Business that's why. If you claim 100% and someone gets sick for whatever reason then they can file lawsuits against the company and claim it was their product that caused it. Don't forget that although these guys set out to obtain full regeneration of many different tissues, they are still a business and they're smart enough to know that even if it is total scar free regeneration, they probably wouldn't market their product as such; especially if you have many different humans of all shapes and sizes undergoing this treatment.
Everyone has to consider all the possibilities based on the information given to us at the current time. Writers and the media aren't very reliable to me unless an actual researcher is being interviewed or talked to. I'm not even reliable either. I just allow you to view my perspective and way of thinking based on my own personal research.
48 minutes ago, Tano1 said:As I said before that the margin could be an end result of their regenerated skin. If it is, then that margin wouldn't heal on its own because it's slightly pitted and we all know how difficult it is to deal with pitting. Might be very small and un-noticeable though.Sprays and Disinfectants that release bacteria killing agents usually have something like this written on the label: "kills 99.9% bacteria." Why wouldn't they just put 100%? Business that's why. If you claim 100% and someone gets sick for whatever reason then they can file lawsuits against the company and claim it was their product that caused it. Don't forget that although these guys set out to obtain full regeneration of many different tissues, they are still a business and they're smart enough to know that even if it is total scar free regeneration, they probably wouldn't market their product as such; especially if you have many different humans of all shapes and sizes undergoing this treatment.
Everyone has to consider all the possibilities based on the information given to us at the current time. Writers and the media aren't very reliable to me unless an actual researcher is being interviewed or talked to. I'm not even reliable either. I just allow you to view my perspective and way of thinking based on my own personal research.
You're a bit off, 10 days isn't enough for any scar to fully heal, there is a remodeling phase that continues for months.
There is a difference between scar free and scarless healing. Think of scarless as extremely close to being like the original tissue, scar free means 100 percent without fail regeneration. Also, you need to consider that their skin constructs have an in tact dermis. This allows for regeneration over the long term. The margin would likely fade over time at 10 days there are still a ton of blood vessels helping the scar heal. Think of any red scar that fades over time.