Acne.org Products
5 hours ago, Anish004 said:are all informarion regarding swine ? have PolarityTe showed this with Human ?
Yes, it's pre clinical, pigs are often used because their skin is similar. And you have to remove all skin to regenerate appendages, the appendages are found in the dermis, the deepest layer of the skin. All dermal substitutes only cover the epidermis which is why they all suck, and they are stupidly expensive which is why SkinTe is using 3d printing which vastly cuts costs. The paste like substance they use also seems more efficient than sheets of skin substitutes.
i will try to call them tomorrow morning
1 minute ago, damnBOY said:i will try to call them tomorrow morning
improvement is bullsh** IF IT Works it will erase strech marks ,improvement is nothing strech marks will still be there and they will be les visible because they have the same color with the surrounding skin
37 minutes ago, damnBOY said:do you think tropoelastin will work??? they are going to end clinical trials...they are saying that tropoelastin lead to skin regeneration some way
idk I have burn scars, I don't know much about stretch marks, could always try this https://www.reddit.com/r/timferriss/comments/3hrcnn/charles_poliquin_stretch_marks_dosage_for_gotu/
11 minutes ago, 34erer34 said:idk I have burn scars, I don't know much about stretch marks, could always try this https://www.reddit.com/r/timferriss/comments/3hrcnn/charles_poliquin_stretch_marks_dosage_for_gotu/
herbs .....:( i doupt they will gonna work....tropoelastin may work for atrophic scars
1 hour ago, damnBOY said:1 hour ago, 34erer34 said:idk I have burn scars, I don't know much about stretch marks, could always try this https://www.reddit.com/r/timferriss/comments/3hrcnn/charles_poliquin_stretch_marks_dosage_for_gotu/herbs .....:( i doupt they will gonna work....tropoelastin may work for atrophic scars
at least try it, otherwise you're just being whiny
in my opinion is waste of time and waste of Money. is better to save my Money for the big treatment.....my strech marks are not that bad when i am on clothes but for the fitness modelingi want to follow are so fucking BAD....I HAVE already 10.000 euros ready and i want to save more because elastatherapy will not be Cheap 300euros for 1mg tropoelastin is not cheap
10 minutes ago, damnBOY said:in my opinion is waste of time and waste of Money. is better to save my Money for the big treatment.....my strech marks are not that bad when i am on clothes but for the fitness modelingi want to follow are so fucking BAD....I HAVE already 10.000 euros ready and i want to save more because elastatherapy will not be Cheap 300euros for 1mg tropoelastin is not Cheap
i wanted to build muscles and i did it fast and now my arms have bad looking strech marks and it killing me..... i am Young i am 19 i can wait 4-5 year for elastatherapy and polarityTE has said that they will bring skinte on the Marketby 2018 for burns soi dont think so it will take more than 5 years to fix my strech marks with skite
f me bro i had bad luck i destroyed my self with my own hands because i wanted to follow my dreams, it killing me bro
i have try everything from creams and laser therapy nothing Works .....all bulls* just now my strech marks are white and not red
ALL WASTE OF MONEY
when they say improvement they want to steal your Money
@34erer34 You have a point, but we dont know exactly what Polarity team is doing, only guesses. And the main moment is that, that they said by themself skinTE would work with an old scars. And not the last point is the profit, even if PolarityTE is a team of people who truely want to help a humanity, they need money, nobody is saint (as i got they dont reply to anybody, but they could be very busy as well or be afraid of giving a false hope). So, ofc there are thousands of burn victims every year, but the number of people with the really severe burns (above 30% 3rd degree) is lesser. So it'll hard to make money only on burns but it's a start point, cuz people have no choice (actually they have, but all of us know to what it'll lead) and like the SkinGun product, it could drastically reduce the time of healing (from 30 days to 8-10, as SkinGun team said, but they did only 2nd degree burn). So even if product will not bring the true scarless healing, at least for people who were burnt it'll not a big problem comparing to start such treatment on a healthy skin. So the market where people already have a different tipe of old scar is larger and so much more profitable. But it's also so far away from the anti-aging market, I believe it's a true goal. Millions of people every year do tons of cosmetic procedures, and it's grow every year. If polarityTE could bring the true all layers skin scarless regeneration, It'll solve a lot of problems, even a volume loss after your 40s. I see an another problem, what will be with the others companies who produce beauty treatments? In a case if skinTE truely need to slice your skin, they will live, but if it could work as some kind of cell injection, most of them will fade (but personally I can't imagine how it could work without skin removing, it's just a miracle for me, cuz there are not any innovative component according to their patent, scientists before them would discovered it earlier in that way). So there are could some lobby actions that could slow down FDA approval.
But in any case, the success of their human trials will boost a lot of new products and new methods, so it'll be really possible to repair our skin. Btw, the skingraft company recently has received boost from FDA, so it'll be possible within 1-3 years I think to make a cosmetic treatment from SkinTE.
And about surgeons that you think never will be doing such procedure. In my country I have a plenty of recell clones, so ones we get a proven scarless skin method, another doctors will use it in their practise, cuz it'll boost their clinics and profit. And to start it, they could start a trials where you can participate, but you need to sign a document, which says that you'll accept all the risks. So not every surgeon, there are will some who will try such a gamble, and in my country absolutely legally. Excision and then applying the skinTE product (which i guess will be like sheet of papers or cell spray) is not the same as face or head transplantation. One doctor can afford it, but he need a skinTE product or technology ofc.
9 hours ago, Raster said:It's an exciting time to be sure.
Haha, for me it's a horrid time. What will we have, if they fail? I like this topic bcuz of lots of optimistic persons. A year ago I thought only the 3d printed skin could be a solution, but now I have a faith into Polarity. And it seems to be more real in the near future, cuz printed skin it's about 10 years I guess...But if we look on realself website, there are so many stories of people of previous generation, who struggled with scars and burns whole their lifes and this is so sad. Will we the luckier? Cuz I'm sure the next 50-100 years will solve all skin wound and acne problems (and discover another one, but it's not our story :P).
not scar related but a future treatment for acne only.
2 hours ago, GeneTrouble said:@34erer34 You have a point, but we dont know exactly what Polarity team is doing, only guesses. And the main moment is that, that they said by themself skinTE would work with an old scars. And not the last point is the profit, even if PolarityTE is a team of people who truely want to help a humanity, they need money, nobody is saint (as i got they dont reply to anybody, but they could be very busy as well or be afraid of giving a false hope). So, ofc there are thousands of burn victims every year, but the number of people with the really severe burns (above 30% 3rd degree) is lesser. So it'll hard to make money only on burns but it's a start point, cuz people have no choice (actually they have, but all of us know to what it'll lead) and like the SkinGun product, it could drastically reduce the time of healing (from 30 days to 8-10, as SkinGun team said, but they did only 2nd degree burn). So even if product will not bring the true scarless healing, at least for people who were burnt it'll not a big problem comparing to start such treatment on a healthy skin. So the market where people already have a different tipe of old scar is larger and so much more profitable. But it's also so far away from the anti-aging market, I believe it's a true goal. Millions of people every year do tons of cosmetic procedures, and it's grow every year. If polarityTE could bring the true all layers skin scarless regeneration, It'll solve a lot of problems, even a volume loss after your 40s. I see an another problem, what will be with the others companies who produce beauty treatments? In a case if skinTE truely need to slice your skin, they will live, but if it could work as some kind of cell injection, most of them will fade (but personally I can't imagine how it could work without skin removing, it's just a miracle for me, cuz there are not any innovative component according to their patent, scientists before them would discovered it earlier in that way). So there are could some lobby actions that could slow down FDA approval.
But in any case, the success of their human trials will boost a lot of new products and new methods, so it'll be really possible to repair our skin. Btw, the skingraft company recently has received boost from FDA, so it'll be possible within 1-3 years I think to make a cosmetic treatment from SkinTE.
And about surgeons that you think never will be doing such procedure. In my country I have a plenty of recell clones, so ones we get a proven scarless skin method, another doctors will use it in their practise, cuz it'll boost their clinics and profit. And to start it, they could start a trials where you can participate, but you need to sign a document, which says that you'll accept all the risks. So not every surgeon, there are will some who will try such a gamble, and in my country absolutely legally. Excision and then applying the skinTE product (which i guess will be like sheet of papers or cell spray) is not the same as face or head transplantation. One doctor can afford it, but he need a skinTE product or technology ofc.
I'm sure there will be something for acne scars, my point really is that skinte is way too aggressive for acne scars. No dr is going to cut up your face like that, and if they do in the future it is decades before it will be considered safe enough. Burns and surgical scars are really hard on the body which is why there is a need to get rid of them, acne scars? Not so much.
1 hour ago, 34erer34 said:3 hours ago, GeneTrouble said:@34erer34 You have a point, but we dont know exactly what Polarity team is doing, only guesses. And the main moment is that, that they said by themself skinTE would work with an old scars. And not the last point is the profit, even if PolarityTE is a team of people who truely want to help a humanity, they need money, nobody is saint (as i got they dont reply to anybody, but they could be very busy as well or be afraid of giving a false hope). So, ofc there are thousands of burn victims every year, but the number of people with the really severe burns (above 30% 3rd degree) is lesser. So it'll hard to make money only on burns but it's a start point, cuz people have no choice (actually they have, but all of us know to what it'll lead) and like the SkinGun product, it could drastically reduce the time of healing (from 30 days to 8-10, as SkinGun team said, but they did only 2nd degree burn). So even if product will not bring the true scarless healing, at least for people who were burnt it'll not a big problem comparing to start such treatment on a healthy skin. So the market where people already have a different tipe of old scar is larger and so much more profitable. But it's also so far away from the anti-aging market, I believe it's a true goal. Millions of people every year do tons of cosmetic procedures, and it's grow every year. If polarityTE could bring the true all layers skin scarless regeneration, It'll solve a lot of problems, even a volume loss after your 40s. I see an another problem, what will be with the others companies who produce beauty treatments? In a case if skinTE truely need to slice your skin, they will live, but if it could work as some kind of cell injection, most of them will fade (but personally I can't imagine how it could work without skin removing, it's just a miracle for me, cuz there are not any innovative component according to their patent, scientists before them would discovered it earlier in that way). So there are could some lobby actions that could slow down FDA approval.
But in any case, the success of their human trials will boost a lot of new products and new methods, so it'll be really possible to repair our skin. Btw, the skingraft company recently has received boost from FDA, so it'll be possible within 1-3 years I think to make a cosmetic treatment from SkinTE.
And about surgeons that you think never will be doing such procedure. In my country I have a plenty of recell clones, so ones we get a proven scarless skin method, another doctors will use it in their practise, cuz it'll boost their clinics and profit. And to start it, they could start a trials where you can participate, but you need to sign a document, which says that you'll accept all the risks. So not every surgeon, there are will some who will try such a gamble, and in my country absolutely legally. Excision and then applying the skinTE product (which i guess will be like sheet of papers or cell spray) is not the same as face or head transplantation. One doctor can afford it, but he need a skinTE product or technology ofc.I'm sure there will be something for acne scars, my point really is that skinte is way too aggressive for acne scars. No dr is going to cut up your face like that, and if they do in the future it is decades before it will be considered safe enough. Burns and surgical scars are really hard on the body which is why there is a need to get rid of them, acne scars? Not so much.
Not sure about acne scars, but I can definitely see SkinTE being used for say a traumatic accident scar on the face. I don't really see the difference, if it fully regenerates skin then it fully regenerates skin. "Cutting" up the face shouldn't really be an issue. Maybe they will devise a method where they do certain sections at a time.
Why can't u guys read the patent that I sent u? Anyways it says the following;
The invention relates to methods for making and methods for using constructs of micro-aggregate multicellular grafts containing isolated Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for the delivery, application, transplantation, implantation, directed seeding, directed migration, directed tracking, in setting, laminating and/or injection of the cellular element generating, regenerating, enhancing and/or healing epithelial systems, glands, hair, nerves, bone, muscle, fat, tendons, blood vessels, fascia, ocular tissues and peptide secreting cellular elements for use in wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications.
I think with other scar types apart from burns it can be injected and the cells can be transplanted within the scar. Basically same way as fat grafting or fillers are used currently to improve appearance of scars/stretchmarks. @damnBOY@mjg713
35 minutes ago, SunnyX said:Why can't u guys read the patent that I sent u? Anyways it says the following;
The invention relates to methods for making and methods for using constructs of micro-aggregate multicellular grafts containing isolated Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for the delivery, application, transplantation, implantation, directed seeding, directed migration, directed tracking, in setting, laminating and/or injection of the cellular element generating, regenerating, enhancing and/or healing epithelial systems, glands, hair, nerves, bone, muscle, fat, tendons, blood vessels, fascia, ocular tissues and peptide secreting cellular elements for use in wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications.
I think with other scar types apart from burns it can be injected and the cells can be transplanted within the scar. Basically same way as fat grafting or fillers are used currently to improve appearance of scars/stretchmarks.
then suppose for a chickenpox scar its injected like a filler and scar vanish
Yeah sort of but it would not make any sense to remove such a small scar, because they need a sample of your skin first. For your scar I would suggest you go and see a dermatologist to get it microneeded! So it make Sense for people with large areas covered with scars such as acne / burn / surgical scars and stretchmarks.
31 minutes ago, SunnyX said:Yeah sort of but it would not make any sense to remove such a small scar, because they need a sample of your skin first. For your scar I would suggest you go and see a dermatologist to get it microneeded! So it make Sense for people with large areas covered with scars such as acne / burn / surgical scars and stretchmarks.
microneedling may fill the indentations but what about its texture it remains same of scar tissue
9 hours ago, 34erer34 said:I'm sure there will be something for acne scars, my point really is that skinte is way too aggressive for acne scars. No dr is going to cut up your face like that, and if they do in the future it is decades before it will be considered safe enough. Burns and surgical scars are really hard on the body which is why there is a need to get rid of them, acne scars? Not so much.
I can tell you that once PolarityTE has proven that it can successfully regenerate third degree wounds its wouldn't be a problem for a surgeon to cut up the skin for treatment. May I ask you,what is the dilemma here since it CAN regenerate the skin fully? You could say it is too aggressive or whatever but the end result the skin would be fully regenerated so it doesn't even matter. Like has any mother who went through C-section would say it is too aggressive (Literally cutting up the belly area) over natural birth?
You are having the dilemma because you are not sure whether this product works. If you are living in the era before the Wright Brothers invented the airplane and if someone from the future told you you can travel by air on a machine that weighs tens of thousands of kg, you would also think said person is insane and no way in hell would such a thing ever exist. Too risky to ever workandthe machine would fall off the sky, no one would risk their life travelling on airwould be your initial thoughts.
Point in case, there are way more controversial surgeries being done. There are several successful face transplants, literally taking someone's else face and implanting to another person. Recently, there was even a head transplant being planned. Now slicing up some skin (That would have regenerated anyway applying PolarityTE)sounds like child's play ain't it?
http://ammrf.org.au/news-and-media/innovation-in-action/fast-tracking-elastin-to-market/
Prof. Tony Weiss from the University of Sydney in conjunction with Elastagen Pty Ltd has been awarded a $1million Translation Award from the Wellcome Trust to fast track their elastin-based synthetic skin to clinical trials. They will refine and optimise its physical and biological properties so this innovative material can be tested for its safety and efficacy in repairing full thickness skin wounds. They aim to use the mesh to help wounds like those that arise from injury, surgery or disease heal faster and without scarring.
Elastin is the bodys naturally occurring elastic protein and Prof. Weiss and his research group have depended on confocal and scanning electron microscopy in the AMMRF at the University of Sydney to develop and improve their elastin products. Its from 2015 but they already do clinical trials.....