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[Sticky] Scarless Healing

 
MemberMember
47
(@damnboy)

Posted : 07/18/2017 10:49 am

31 minutes ago, Binga said:

This might be available next year for surgical scars

https://www.scarxtherapeutics.com/technology-1

they say reduction of scars :( not scarless healing

 

48 minutes ago, CollegeKidd said:
You messaged Sunogel? When did this take place? I'm very curious to know about clinical trials

today

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MemberMember
36
(@mjg713)

Posted : 07/18/2017 3:19 pm

http://www.prnewswire.com/news-releases/us-fda-designates-mallinckrodts-stratagraft-as-regenerative-medicine-advanced-therapy-300489200.html This is not scarless healing, but it is a regenerative skin technology graft that received accelerated approval by he FDA under the "21st Century Cures Act". This is good news because it shows that they will be giving accelerated approval to future skin regeneration technologies that truly are scarless such as SkinTE.

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MemberMember
47
(@damnboy)

Posted : 07/18/2017 3:28 pm

7 minutes ago, mjg713 said:
http://www.prnewswire.com/news-releases/us-fda-designates-mallinckrodts-stratagraft-as-regenerative-medicine-advanced-therapy-300489200.html This is not scarless healing, but it is a regenerative skin technology graft that received accelerated approval by he FDA under the "21st Century Cures Act". This is good news because it shows that they will be giving accelerated approval to future skin regeneration technologies that truly are scarless such as SkinTE.

But PolarityTE say they will bring skinTE in the Market by 2018 if it Works for humans how is this possible?

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MemberMember
36
(@mjg713)

Posted : 07/18/2017 4:01 pm

32 minutes ago, damnBOY said:
41 minutes ago, mjg713 said:
http://www.prnewswire.com/news-releases/us-fda-designates-mallinckrodts-stratagraft-as-regenerative-medicine-advanced-therapy-300489200.html This is not scarless healing, but it is a regenerative skin technology graft that received accelerated approval by he FDA under the "21st Century Cures Act". This is good news because it shows that they will be giving accelerated approval to future skin regeneration technologies that truly are scarless such as SkinTE.

But PolarityTE say they will bring skinTE in the Market by 2018 if it Works for humans how is this possible?

PolarityTE is a little different. It isn't using any drug that aren't already FDA approved. All substrates used are either natural from the human body or already FDA approved. This results in a very fast approval process.

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MemberMember
92
(@binga)

Posted : 07/18/2017 8:51 pm

http://www.elastagen.com/

For those in the UK they are recruiting people for their acne scar clinical trial.

https://clinicaltrials.gov/ct2/show/NCT03056235

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MemberMember
40
(@anish004)

Posted : 07/18/2017 9:21 pm

what is ELAPR002f andELAPR002g ?

what is ELAPR002f andELAPR002g ?

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MemberMember
47
(@damnboy)

Posted : 07/19/2017 3:28 am

Great news from elastage, they focus on strech marks and aeshetic applications

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MemberMember
1
(@tony82)

Posted : 07/19/2017 4:26 am

56 minutes ago, damnBOY said:

 Great news from elastage, they focus on strech marks and aeshetic applications

Great link. That video is over two years old, unfortunately their pipeline is still only in preclinical stage for scar revisions.
http://www.elastagen.com
elastagen-product-pipeline-5.jpg

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MemberMember
40
(@anish004)

Posted : 07/19/2017 8:03 am

any more updates or infos ?which give scarred people hope

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MemberMember
92
(@binga)

Posted : 07/19/2017 9:41 am

5 hours ago, Tony82 said:
Great link. That video is over two years old, unfortunately their pipeline is still only in preclinical stage for scar revisions.
http://www.elastagen.com
elastagen-product-pipeline-5.jpg

Their plan is to combine synthetic elastin with a dermal filler. Depending on the clinical trial the injectable product should be available next year. 

2 hours ago, Anish004 said:

any more updates or infos ?which give scarred people hope

If you have the money the only high end treatment available right now for scars is nano fat injections with radio frequency micro needling. Everything else is going through clinical trials.

https://www.realself.com/question/switzerland-ch-nano-fat-injections-work-acne-scars

http://www.facesplus.com/2016/09/nanofat/

http://www.usa.lutronic.com/pdf/CaseStudy_AcneScars_Ibrahimi_ConnecticutSkinInstitute.pdf

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MemberMember
40
(@anish004)

Posted : 07/19/2017 10:59 am

what is nano fat injection ? scar improving or scarless healing ? give details

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MemberMember
47
(@damnboy)

Posted : 07/19/2017 1:26 pm

3 hours ago, Binga said:
Their plan is to combine synthetic elastin with a dermal filler. Depending on the clinical trial the injectable product should be available next year.
If you have the money the only high end treatment available right now for scars is nano fat injections with radio frequency micro needling. Everything else is going through clinical trials.

https://www.realself.com/question/switzerland-ch-nano-fat-injections-work-acne-scars

http://www.facesplus.com/2016/09/nanofat/

http://www.usa.lutronic.com/pdf/CaseStudy_AcneScars_Ibrahimi_ConnecticutSkinInstitute.pdf

So fast one year after clinical trials will be avaliable?

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0
(@Anonymous)

Posted : 07/19/2017 7:45 pm

On 7/18/2017 at 11:49 AM, damnBOY said:
they say reduction of scars :( not scarless healing

 

today

Did he reply back to your question about clinical trials?

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MemberMember
40
(@anish004)

Posted : 07/20/2017 1:03 am

not indentation of scars sucks or raising..

but what sucks is scar tissue ...no pores no follicles and shiny... thats why they look annoying

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MemberMember
47
(@damnboy)

Posted : 07/20/2017 2:04 am

6 hours ago, CollegeKidd said:
On Ž18Ž/Ž7Ž/Ž2017 at 6:49 PM, damnBOY said:
they say reduction of scars :( not scarless healing

 

today

Did he reply back to your question about clinical trials?

nope :(

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MemberMember
47
(@damnboy)

Posted : 07/20/2017 2:39 am

"Our research has exciting and wide-ranging impacts. As well as burns, wound repair and scar remodelling, synthetic skin has some enticing cosmetic benefits. An injectable version that could be used to help repair small scars, stretch marks and acne scars". (TROPOELASTIN.WEISS LAB)

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MemberMember
92
(@binga)

Posted : 07/20/2017 7:55 am

18 hours ago, damnBOY said:
So fast one year after clinical trials will be avaliable?

The clinical trial is supposed to be completed by december 2017. If the results are positive the product should be readily available. They are already selling it for R&D purposes in Australia.

20 hours ago, Anish004 said:

what is nano fat injection ? scar improving or scarless healing ? give details

It's basically stem cell injection. Scarless healing for shallow scars. Scar improving for deep scars.

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MemberMember
47
(@damnboy)

Posted : 07/20/2017 8:35 am

39 minutes ago, Binga said:
The clinical trial is supposed to be completed by december 2017. If the results are positive the product should be readily available. They are already selling it for R&D purposes in Australia. It's basically stem cell injection. Scarless healing for shallow scars. Scar improving for deep scars.

what about strech marks?

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MemberMember
92
(@binga)

Posted : 07/20/2017 4:59 pm

8 hours ago, damnBOY said:
9 hours ago, Binga said:
The clinical trial is supposed to be completed by december 2017. If the results are positive the product should be readily available. They are already selling it for R&D purposes in Australia. It's basically stem cell injection. Scarless healing for shallow scars. Scar improving for deep scars.

what about strech marks?

No idea

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MemberMember
0
(@isolated)

Posted : 07/20/2017 5:05 pm

On 7/18/2017 at 5:38 AM, SunnyX said:

Noo unfortunately both are not available and they have so far also not done any human trials in which they can prove that their system works. Polarityte can also be applied in combination with a hydrogel. So I think as of now the best hope is SkinTE!

What about those of us who are in our late teens to early 20's with severe premature aging, including but not limited to: fully developed nasolabial folds, wrinkles, thinning of the skin and fat loss under the eyes.

I have acne scars but they concern me less than the premature aging I am being afflicted with. Do you think SkinTE will be an appropriate approach for me and others with the combination of issues like premature aging, fat loss and scarring?

I used retin-a to try and improve my scars and it ended up making things 100x worse in the aging department, so I am desperate for a cure. Until then I am sitting at home isolated all day until something comes to fruition.

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MemberMember
0
(@isolated)

Posted : 07/20/2017 5:06 pm

On 7/11/2017 at 6:17 AM, Binga said:

I think some doctors are already using Epicel, lab grown skin graft from biopsy, to treat burns. Wonder if it can be used for scars as well.

http://vcel.com/product-portfolio/

http://www.doctoralizadeh.com/cosmoplastic-surgery/reconstructive-surgery/regenerative-medicine.html

I think I may try some of his regenerative procedures for my premature aging and scarring. Do you think it's worth a shot?

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MemberMember
1
(@genetrouble)

Posted : 07/20/2017 8:13 pm

2 hours ago, Isolated said:
What about those of us who are in our late teens to early 20's with severe premature aging, including but not limited to: fully developed nasolabial folds, wrinkles, thinning of the skin and fat loss under the eyes.

I have acne scars but they concern me less than the premature aging I am being afflicted with. Do you think SkinTE will be an appropriate approach for me and others with the combination of issues like premature aging, fat loss and scarring?

I used retin-a to try and improve my scars and it ended up making things 100x worse in the aging department, so I am desperate for a cure. Until then I am sitting at home isolated all day until something comes to fruition.

How did you use retin-a that it damaged your skin so bad? Do you have a super dry and sensitive skin type and have used retin-a a lot? For oily skin it fits well for every day using even with 0.1% gel. The only tips are that you should apply it at night and use sunscreen in day time.
Have patience, 2-3 months untill we'll get the information about SkinTE success or fail on humans. Theoretically, polarityTE team said, that it could regenerate 3rd degree burn on pig's skin, and 3rd degree burn is affect all 3 layers of skin, including fat tissue (subcutaneous fat). And anti-aging market is extremely far more profitable than all scars and burns markets together. So it'll be bloody procedure, but if it'll be possible, human skin could be regrow completely, the question is how scarless it'll be. For rhytids it'll still have no effect, but Polarity have a muscle regeneration product in plan, so if they will be succes wit SkinTE, we could get a really revolutionary aging treatment.

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MemberMember
40
(@anish004)

Posted : 07/21/2017 1:35 am

have anyone heard about decorin ?? its a substance found in body which can be used for scarless healing.decorin arrange collagen in healing wounds and grow neccesary follicles and glands .....

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MemberMember
151
(@candy-says)

Posted : 07/21/2017 11:05 pm

`

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MemberMember
0
(@isolated)

Posted : 07/22/2017 4:57 pm

On 7/20/2017 at 6:13 PM, GeneTrouble said:
How did you use retin-a that it damaged your skin so bad? Do you have a super dry and sensitive skin type and have used retin-a a lot? For oily skin it fits well for every day using even with 0.1% gel. The only tips are that you should apply it at night and use sunscreen in day time.
Have patience, 2-3 months untill we'll get the information about SkinTE success or fail on humans. Theoretically, polarityTE team said, that it could regenerate 3rd degree burn on pig's skin, and 3rd degree burn is affect all 3 layers of skin, including fat tissue (subcutaneous fat). And anti-aging market is extremely far more profitable than all scars and burns markets together. So it'll be bloody procedure, but if it'll be possible, human skin could be regrow completely, the question is how scarless it'll be. For rhytids it'll still have no effect, but Polarity have a muscle regeneration product in plan, so if they will be succes wit SkinTE, we could get a really revolutionary aging treatment.

Well unfortunately despite advisement not to--I started on .1% retin-1 (I know it was immature and stupid) thinking I could handle it. I ended up applying it daily thinking the burning feelings, extreme redness and peeling would only be temporary and my skin would adapt fairly fast. It really fucked up my skin like nothing else ever has. I was depressed before, but now, I am suicidal.

I have plenty of patience but at the same time I must bridge my patience by being proactive about my situations with my skin. I need to do something soon to help alleviate the worst of my depression, and I hope I can find something more robust than say recell or some of the other options out there; I was thinking of traveling long distances and seeking out lesser known regenerative procedures if I can find them. Certainly no cure, but it's a start. I have suffered for far too long to remain stagnant.

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