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I agree with Rez 77 in the fact that it might be decades before scarless healing is found if ever. I has been 36 or so since the last big acne med came out with accutane. The best defense in the first place is not to let it get to the point of acne scarring in the first place. With accutane and spiro out there plus retin A.......nobody today should have acne scarring. I was a teen wayyy back in the 70's before these came out and my skin scarred. It is hard to change 1000's of years of evolution of the human body but one can do it. It takes time.
2 hours ago, nikkigirl said:I agree with Rez 77 in the fact that it might be decades before scarless healing is found if ever. I has been 36 or so since the last big acne med came out with accutane. The best defense in the first place is not to let it get to the point of acne scarring in the first place. With accutane and spiro out there plus retin A.......nobody today should have acne scarring. I was a teen wayyy back in the 70's before these came out and my skin scarred. It is hard to change 1000's of years of evolution of the human body but one can do it. It takes time.
My skin actually became severely scarred because of how badly I broke out while taking accutane.
Hey guys. This Isn't acne scarring related but still somewhat related in a way. http://www.nbcsandiego.com/news/local/UCSD-Professor-Develops-Vaccine-for-Acne-420127674.html
I'm just happy that the new generation , won't likely experience what we had to go through in our teenage years or even to some unlucky adults. If we get rid of the root cause of the acne scarring, well that means humanity as we know It, would not know what it's like to have acne nor acne scarring. I'm a little bit jealous for the young one's right now to be honest, how I wish It came way before my puberty years kicked in.
@ acastro0069
there is/was actually an Austrian Biomed company working on a vaccine against Acne since 2014.
My medical know-how unfortunately is near 0, so i have no idea whether the approach is similar to the UCSD-researchers or not.
Anyhow, for anybody interested here is the link - the lead researcher is called Sanja Selak / the company "Origimm"
http://www.origimm.com/rd-programs/acne-vulgaris/our-solution/
the - slightly depressing - thing though is there seems to be no news on the current status of their research; at least i couldn't find anything .....
so there are people working on it - but god knows when if at all those will become available to the patients
19 hours ago, SunnyX said:@seabs135
Hi,
complete regeneration took place in 2011?
could please provide more informs about that.
thanks
The dextran hydrogel has been licensed by gemstone biotherapeutics. They tested the hydrogel on pigs which hv similar skin to humans and there they don't anymore say complete regeneration of skin. And they are more looking into chronic wounds. So I guess in humans it does not regenerate normal skin
46 minutes ago, SunnyX said:@seabs135The dextran hydrogel has been licensed by gemstone biotherapeutics. They tested the hydrogel on pigs which hv similar skin to humans and there they don't anymore say complete regeneration of skin. And they are more looking into chronic wounds. So I guess in humans it does not regenerate normal skin
I have been looking at this since 2011. In 2011 the hydrogel highlighted complete regeneration. Gemstone have indicated the hydrogel for use in diabetic wounds. With regards to the porcine testing. In no paper have they disclosed they gotincomplete regeneration. In the paper Acellular hydrogels for regenerative burn wound healing: translation from a porcine model they testeda couple ofmechanisms which the hydrogel promoted regeneration, this is highlighted in the introduction... In that paper they highlighted the hydrogel got healing with rete pegs, rete pegs are not found in scarring.
42 minutes ago, seabs135 said:I have been looking at this since 2011. In 2011 the hydrogel highlighted complete regeneration. Gemstone have indicated the hydrogel for use in diabetic wounds. With regards to the porcine testing. In no paper have they disclosed they got incomplete regeneration. In the paper Acellular hydrogels for regenerative burn wound healing: translation from a porcine model they tested a couple of mechanisms which the hydrogel promoted regeneration, this is highlighted in the introduction... In that paper they highlighted the hydrogel got healing with rete pegs, rete pegs are not found in scarring.
work hydrogel for surgical scars ?? According to these data you have presented.
sorryformyenglish 
@seabs135
Gemstone answers a similar question on its FB site as follow:
Sorry - the technology has demonstrated the ability to support the acceleration of wound closure and hence minimize scarring in the wound healing process. ... It is focused on supporting hard to heal wounds.
So i guess the regeneration was only on animals but not on humans and therefore they have moved to more chronic wounds
The terms "sorry" there refers to my question on their mistakes in their previous post which is already deleted..
The terms "sorry" doesnt mean as a negative answer for my question..
They are sorry because their post was cut so they say sorry to me..
However, if you see their answer, they clearly states hair regrowth from wound which indicates complete regeneration
2 hours ago, SunnyX said:@seabs135
Gemstone answers a similar question on its FB site as follow:
Sorry - the technology has demonstrated the ability to support the acceleration of wound closure and hence minimize scarring in the wound healing process. ... It is focused on supporting hard to heal wounds.So i guess the regeneration was only on animals but not on humans and therefore they have moved to more chronic wounds
what wounds ??
@rudy1986
Oh that was ur question on FB? World is small.
Did you get more information as to when they are thinking about clinical trials to Start? I gues they are still testing it on pigs.
I have also written to birchbiomed regarding Fibrostop2, because I think it only prevents Hypertrophic and Keloidal Scars but you will end up still with a normal scar. Let's see if they will reply.
2 hours ago, SunnyX said:@rudy1986
Oh that was ur question on FB? World is small.
Did you get more information as to when they are thinking about clinical trials to Start? I gues they are still testing it on pigs.
I have also written to birchbiomed regarding Fibrostop2, because I think it only prevents Hypertrophic and Keloidal Scars but you will end up still with a normal scar. Let's see if they will reply.
Yes, it only prevents hypertrophic scars but if a person have keloid scars he can to excision them and FS2 prevent back up of keloid and make them invisible.
hope to understood me because I dont speak good english
I just talked to a famous scientist at MIT who specializes in wound closure and regenerative medicine. He said hydrogels were once a hope for many people but they proved ineffective in humans. He also said that at the earliest we might have some kind of therapy by the 2030s but definitely not by 2020 or before the 2030s --and he said --at the most optimistic there may be something by 2030. Okay, so I'm not going to waste the next 13 years of my life on this site. Checking in every few days to read didly squat except you guys who keep posting stuff about hydrogels when you know none of these companies are doing anything except trying to keep their grant money coming in. Wake me up in a decade and a half.
@Rez77
Very true. I guess the scarfree foundation is correct in saying that it will take around 20years. I wish there would be treatment out there now but this is not the case. Hydrogel work on mouses but not on humans.
13 hours ago, Rez77 said:I just talked to a famous scientist at MIT who specializes in wound closure and regenerative medicine. He said hydrogels were once a hope for many people but they proved ineffective in humans. He also said that at the earliest we might have some kind of therapy by the 2030s but definitely not by 2020 or before the 2030s --and he said --at the most optimistic there may be something by 2030. Okay, so I'm not going to waste the next 13 years of my life on this site. Checking in every few days to read didly squat except you guys who keep posting stuff about hydrogels when you know none of these companies are doing anything except trying to keep their grant money coming in. Wake me up in a decade and a half.
hopeless :s:s:@
Yeah @Albaneso,
I am sorry but unfortunately there is nothing going to be out in the next 5 years. But new research by Dr Cotsarelis shows that scarfree healing is possible if hair follicles are grown and then myofibroblast (which is the prime culprit for scaring) changes into fat. But it's still a proof of concept, meaning till clinical trials it would take at least 10years and more.
2 hours ago, SunnyX said:Yeah @Albaneso,
I am sorry but unfortunately there is nothing going to be out in the next 5 years. But new research by Dr Cotsarelis shows that scarfree healing is possible if hair follicles are grown and then myofibroblast (which is the prime culprit for scaring) changes into fat. But it's still a proof of concept, meaning till clinical trials it would take at least 10years and more.
That is not true, with the 21st Century Cures Act if the treatment is using a method currently approved for something else as safe then it can be fast tracked.