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4 hours ago, AI3forever said:http://www.dailymail.co.uk/health/article-4095410/An-end-scars-Breakthrough-heal-wounds-without-leaving-trace.html
https://www.hospimedica.com/surgical-techniques/articles/294767844/reprogramming-fibroblasts-promotes-scarless-healing.htmlFrom what I read in the articles they were successful in reprogramming myofibroblasts (which causes scarring) to adipose fat cells (which will look like normal skin) in human and mouse cells.
I would say keep your hopes up. It seems we do have the technology for scarless healing. It just a matter of time they make it available to common folks.
It wasn't a human body, though. They used skin samples.
http://www.sciencealert.com/scientists-have-figured-out-how-to-make-wounds-heal-without-scars
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It's important to remember that the experiment is just a proof of concept at this stage -it's been shown to work in mice and human skin samples, but it's a very different thing to achieve hair follicle growth in a wound that's attached to a living human being.
But it's a big deal, because until now, scientists thought that converting myofibroblasts into adipocytes was biologically impossible in mammals.
If the team can somehow replicate the results in a human trial - by figuring out how to manipulate the Bone Morphogenetic Protein in scar tissue, for example - it could lead to entirely new ways of wound healing that would be indistinguishable from naturally regenerated skin
4 minutes ago, AI3forever said:They used human samples but that is a good sign because previously it was animals. Now that it has been shown that scarless healing can occur in human cells in a lab setting the last step is to bring it to the masses.
when it will be approved for use in patients? do you have any idea???
On 8/4/2017 at 10:55 AM, scarred2468 said:I don't get what's taking the hydrogels so long, it'sjustdextran. I mean gemstone's doesn't work apparently, so maybe sunogel is fated to be the same. We'll see
Gemstone was primary not designed to treat scarring issues ; their researches do not target this.
Hi
i would like to thank the community here on this forum for bringing up all that information about the research that is going on in scarless wound-healing. i found this thread a good "overview" . Please keep it up guys (and girls) !
Though i had medium-severe Acne vulgaris (which i was lucky enough to leave behind me permanently due to a successful/side-effect free Isotretinoin/Roaccutane treatment about 10 years ago) my interest in this topic now comes from a different angle.
My 3 yr old daughter had an accident which left her with a very visible atrophic scar on her face, and though i do appreciate the options that there are with subcision/fillers, lasers, micor-needling, etc. i fear non of this will give a result she will be happy to live with / the only real option to improve this will be to excise the scar and hopefully heal with a much less visible scar or as i hope as the ultimate goal heal the excision scarless..
I wish all of you that in the future there will be a treatment option that improve/remedy your scars because i know the psychological suffering from this is hard to bear.
Keep up your spirits and keep up bringing on the infos on research.
There are so many people out there in the world suffering from the effects visible scars have on their lives - i wish there would be more great Forums here to connect people and get them organized to push for a common goal and share information..
Thank You all
@C h r i sthank you for your kind words. I would advise you that the information given on this site is not appropriate for a child, especially not a 3 year old. Please consult a Children's dermatological surgeon (one that specializes in children) or a plastic surgeon who again specializes in children. To discuss your child's issue. When we give recommendations here they are for mature adult skin. None of these are appropriate for children's skin which can often heal and have a better success of treatment. I would never do any energy device on a 3 year old, nor would I use harmful chemicals. The young body can often do it's own scarless healing with proper care as the body is constantly healing / growing when we are children.
When we give advice to adults, they often have other issues like aging, cell death, fat loss, suborn fibrosis, declining health, etc which do not factor into this situation. I urge you to research for children's specific traumatic scar treatment (this will be done by a facial plastic surgeon), not on a acne scar site which a child does not deal with.
I know children who have surgical scar revision (z or geometric) who have no signs as adults.
Seriously stop confusing the issues. As of now we have nothing.
Moderator points out we have "cell death, aging, stubborn fibrosis" etc. etc. --yeah so there you have it --it's all about AGING!!!
You can't have scarless healing because YOU CANNOT REVERSE AGING!!! If you want "NEW SKIN" you have to find a way to reverse the aging process. As of now 3-D printers can print a cm squared of skin and it'll take 2 months and cost 50 grand --and then what are you gonna do? Stitch it to your face???? lOLOLOLOL
RECELL is a total scam as well. We really have nothing but: DERMABRASION, LASER, SUBCISION, FILLERS --you can get maybe 10 percent improvement. But most of us need a total new face, new skin. You have any idea how deep the icepick scars are???? THEY'RE SUPER SUPER DEEP. Especially once the collagen is lost. You're fucked.
5 hours ago, Rez77 said:Seriously stop confusing the issues. As of now we have nothing.
Moderator points out we have "cell death, aging, stubborn fibrosis" etc. etc. --yeah so there you have it --it's all about AGING!!!
You can't have scarless healing because YOU CANNOT REVERSE AGING!!! If you want "NEW SKIN" you have to find a way to reverse the aging process. As of now 3-D printers can print a cm squared of skin and it'll take 2 months and cost 50 grand --and then what are you gonna do? Stitch it to your face???? lOLOLOLOL
RECELL is a total scam as well. We really have nothing but: DERMABRASION, LASER, SUBCISION, FILLERS --you can get maybe 10 percent improvement. But most of us need a total new face, new skin. You have any idea how deep the icepick scars are???? THEY'RE SUPER SUPER DEEP. Especially once the collagen is lost. You're fucked.
What does aging have to do with scar-free healing? We're not asking for skin like a new born, we're asking for REGENERATED skin that would match the rest of the skin on our bodies. And believe it or not, it is very much so a possibility that might be in our very near future. It all depends on clinical trials and the medical process.
2 hours ago, Albaneso said:Any new info from hydrogel or FS2 ???
Yes, or sunogel?
On 4/13/2017 at 2:20 PM, Rez77 said:Seriously stop confusing the issues. As of now we have nothing.
Moderator points out we have "cell death, aging, stubborn fibrosis" etc. etc. --yeah so there you have it --it's all about AGING!!!
You can't have scarless healing because YOU CANNOT REVERSE AGING!!! If you want "NEW SKIN" you have to find a way to reverse the aging process. As of now 3-D printers can print a cm squared of skin and it'll take 2 months and cost 50 grand --and then what are you gonna do? Stitch it to your face???? lOLOLOLOL
RECELL is a total scam as well. We really have nothing but: DERMABRASION, LASER, SUBCISION, FILLERS --you can get maybe 10 percent improvement. But most of us need a total new face, new skin. You have any idea how deep the icepick scars are???? THEY'RE SUPER SUPER DEEP. Especially once the collagen is lost. You're fucked.
Calm down dude, CollegeKidd is right.
beautifulambition
thanks for your post. Of course we are going to check everything with pedriatic dermatologist / plastic surgeon.
My thinking is in any event a scar revision/excision would be many years in the future, as i dont think its a good idea to do this at a young age.
By that time if topicals were available that do in fact significantly improve the healing of a scar-revision incision it would be god-sent, thus my interesst in this topic.
That said i would also think non of this could happen anytime soon unfortunately, as there is basically 0 information from the companies upon what an eventual schedule for FDA-approval / start to market market would be. Even on the FS2/BirchBiomed which looks to be the furthest developed so far - Except for their press-release of completion of a clinical trial not even an estimate on a "release-date" can be found.
i read through your FAQ and some of your other posts - i am very impressed, i think you are as much an expert on the subject as one can be without being a dermatologist per se. You might even be much better in advising, since you are not trying to sell a certain treatment to patients - i agree with your point that unfortunately there seem to be a lot of dermatologists trying to push Laser-treatments on patients unnecessarily to get back their investment on the Laser faster.
You are really helping a lot of people to better understand the topic - appreciated very highly.