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On 23/04/2016 at 9:31 PM, mjg713 said:I want to start by saying that I do not have acne. However, I recently acquired a small scar that is troubling me. I found this thread about scarless healing and it interested me that this one day can be a possibility. Without going through 271 pages, can someone tell me the progress of this for say trauma scars or surgical scars? Would these type of scars be easier to treat than acne scars? Is there any estimate on how long we will see this technology? I would be happy with even say 90% improvement compared to completely scarless healing. Thank you in advance.
All scars are the same, In that they are an over production of collagen.
Look into the hydrogel treatment that has been highlighted, which has beenshown to completely regenerate tissue.
On April 26, 2016 at 3:05 PM, seabs135 said:All scars are the same, In that they are an over production of collagen.
Look into the hydrogel treatment that has been highlighted, which has beenshown to completely regenerate tissue.
Ok so I looked into this hydrogel. It seems like a decent concept but haven't read anything too substantial yet. From what I've read, it only has been tested on mice and pigs. Any idea when human trials will start? I'm not looking for necessarily a cure, just something that might make scarring around 90% better. I feel like lasers are too much of a risk because they can make things worse and don't yield great results all the time. I would think that my regular scarring would be a little easier to treat than deeper acne scarring. Any idea where we will be around 5 years time? I think waiting and hoping for something that won't come to us for 15-20 years is a waste of time.
On 29/04/2016 at 0:33 AM, mjg713 said:Ok so I looked into this hydrogel. It seems like a decent concept but haven't read anything too substantial yet. From what I've read, it only has been tested on mice and pigs. Any idea when human trials will start? I'm not looking for necessarily a cure, just something that might make scarring around 90% better. I feel like lasers are too much of a risk because they can make things worse and don't yield great results all the time. I would think that my regular scarring would be a little easier to treat than deeper acne scarring. Any idea where we will be around 5 years time? I think waiting and hoping for something that won't come to us for 15-20 years is a waste of time.
Looking at the gemstone site, it looks iikeagelwill be used on humans in the next year or so...
Btw, imo, you cant define if something is 5% or 90% better. What is 90% to you may 5% to another.
Things are either completely regenerated, or incompletely regenerated...
13 hours ago, seabs135 said:Looking at the gemstone site, it looks iikeagelwill be used on humans in the next year or so...
Btw, imo, you cant define if something is 5% or 90% better. What is 90% to you may 5% to another.
Things are either completely regenerated, or incompletely regenerated...
True, there is nothing such as how many % better.. it is purely subjective... but complete regeneration or incomplete regeneration, it is objective..
On May 4, 2016 at 9:48 AM, seabs135 said:Looking at the gemstone site, it looks iikeagelwill be used on humans in the next year or so...
Btw, imo, you cant define if something is 5% or 90% better. What is 90% to you may 5% to another.
Things are either completely regenerated, or incompletely regenerated...
Ok well if that is the case, is this hydrogel suppose to show complete regeneration? Is this something to be taken seriously or will it be another let down? I am just a little weary about it because it's hard to find any information on it other than this board. On the other hand i would like to believe that we have finally made some progress regarding scars. We have made many medical advances in current years. Do you think anything promising will be developed in the next 10 years or is this all just wishful thinking?
On 06/05/2016 at 0:56 AM, mjg713 said:Ok well if that is the case, is this hydrogel suppose to show complete regeneration? Is this something to be taken seriously or will it be another let down? I am just a little weary about it because it's hard to find any information on it other than this board. On the other hand i would like to believe that we have finally made some progress regarding scars. We have made many medical advances in current years. Do you think anything promising will be developed inXtime or is this all just wishful thinking?
Well I take the objective information in the PNAS type journals and scientific statements more seriously than something stated on a message board. Btw I would guess the things you have been let down by are things that use subjective statements that say something like '50% or 90% 'scar-less' improvement...'You will always be let down by statements like that.
Whereas complete regeneration is objective.
When will it be here? hopefully soon.
full regeneration is something not possible, but a 99% improvement of scar appearence theoretically is possible and what the difference between these two? for the patient nothing, for the science, is everything
full regeneration means that the scar is not a scar anymore, and this is rely on the stem cells or other gene therapy studies.
fading a scar to the point it wont be noticiable anymore will be something achiveable in the hands of good plastic surgeons in a near future
8 hours ago, De Rerum Natura said:full regeneration is something not possible, but a 99% improvement of scar appearence theoretically is possible and what the difference between these two? for the patient nothing, for the science, is everything
full regeneration means that the scar is not a scar anymore, and this is rely on the stem cells or other gene therapy studies.
fading a scar to the point it wont be noticiable anymore will be something achiveable in the hands of good plastic surgeons in a near future
where do you see any report about full regeneration is not possible? All i can see is it is possible which come from scientists' mouth.. or maybe you have more knowledge than them?
Anyway, turning a full thickness wound into perfect skin is already demonstrated on pigs and even humans
Pigs source : Eqalix
Human source : wound induced hair neogenesis in human
10 hours ago, De Rerum Natura said:full regeneration is something not possible, but a 99% improvement of scar appearence theoretically is possible and what the difference between these two? for the patient nothing, for the science, is everything
full regeneration means that the scar is not a scar anymore, and this is rely on the stem cells or other gene therapy studies.
fading a scar to the point it wont be noticiable anymore will be something achiveable in the hands of good plastic surgeons in a near future
Every non injured tissue on your body completely regenerates. Wounds with a diffusion distance less than 2mm can regenerate completely. Tissues that reepithialize in under 2weeks completely regenerate,.. Then you have various scientific papers that have shown complete regeneration that have been shown on this thread..
So it seems like there is 2 different viewpoints on this. One is that full regeneration is possible and another is that we can improve scars significantly enough where they are not visible, but not 100% regeneration. Personally I would be happy with "99% improvement" if it can make a scar not visible to the human eye. If this is the case, what kind of technology will be used in the future to do this? lasers? It seems as though lasers are not that effective, so I don't see that happening. There just seems to be a lot of contradictions, it would be nice to know what lies ahead and maybe some type of timeline. Anyone see any significant advances in the next 5 years?
sorry i didnt mean that it is impossible, i mean for us is something not possible at moment. I do believe that the advancements in science will provide us the capacity of regenerating a scarless wound, but i think it will take years maybe decades to be something we could use being optimistic. after being affected with scars became more interested in the regeneration studies and i found that the regeneration is one of the most fantastic things in nature
read some pappers regardingthe aloxlt salamander and alot of texts regarding scarless healing and wound healing process.
i look foward for a regeneration method in medicine being a great sucess in the future i think it will be a real thing andi really hope it can be a close dream for us, studies, things, testsare going on in a fast pace than years back, is VERY GOOD to see that new perspectives regarding regeneration are on their way
but still, where are wenow? what options we have? how can wecount on that future? people here, and me included already suffered enough, maybe in ten years this section in this forum will be forgotten because some cure maybe arise but maybe we gonna still be here pressing f5 and hoping for something and meantime we get older and older, and see that our life passed through and we suffered most part of it because we are unlucky,
thats sad and we still dont have good alternatives and my fear is simply relying on something that can be frustrating
please correct me if i said some bullshit im not here to pretend knowing things my intention here is simply learn
On 5/9/2016 at 5:57 AM, rudy1986 said:where do you see any report about full regeneration is not possible? All i can see is it is possible which come from scientists' mouth.. or maybe you have more knowledge than them?Anyway, turning a full thickness wound into perfect skin is already demonstrated on pigs and even humans
Pigs source : Eqalix
Human source : wound induced hair neogenesis in human
Rudy is this the study link that you mentioned?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054871/
That and this :
http://www.ncbi.nlm.nih.gov/pubmed/26504521
Skin scars are the normal and inevitable outcome of mammalian tissue repair.Scarless skin healing occurs in early mammalian embryos,and complete regeneration occurs in lower vertebrates, such as salamanders, and invertebrates. A scar may therefore be the price we pay for evolutionary survival after wounding. As with any scar, it will heal and fade over time, but will never disappear. 🙁
12 hours ago, rudy1986 said:That and this :
http://www.ncbi.nlm.nih.gov/pubmed/26504521
I think this is a step forward - but a small one as it is still on freaking mice.The skin, together with all its functioning mini-organs (hair follicles, sweat glands, sebaceous glands, blood vessels), is an organ or even an entire organ system (called the "integumentary system" by scientists). Regenerating the entire system will be incredibly complicated.
So it seems like a lot of people are very pessimistic about this. I actually feel optimistic about this considering we have made so many medical advancements in recent years and scientists are continuing to study this topic getting closer and closer. I know that I would be completely satisfied with a treatment that does't biologically completely get rid of the scar, but improves it's color and texture so much it isn't visible. If this hydrogel really works, that would really be an amazing breakthrough. I honestly wouldn't be surprised if the government already has a "cure" and is just holding out on us for the time being. I really hope we can make some significant progress at least in the not too far future.
7 hours ago, De Rerum Natura said:United States actually invest much money in regenerative medicine
their aim is probably one day be capable of regenerate limbs from the amputated war veterans and etc..
Well i'm sure that reengage skin scars is a lot easier than regenerating limbs? So we should be seeing advancements in that area first.
On 5/14/2016 at 4:05 PM, Tasyo said:
Hi, I am a 2nd Year College now. I started to have acne problem when i was 3rd year highschool. And now i have a serious deep acne scars all over my face. Please help me. I thinking about a Diamond Peeling. Does this will work ?
Please go to dermatologist. Diamond peel won't work
We should have clinical application of something that is better than 70 percent improvement by 2080. Don't know how old you guys are but if you can make it to then another 60 years you should be able to get the work done. Though there will not be any significant anti-aging technologies till 3200 so unfortunately you will only be able to achieve "scarless" healing of much older aged skin. Keep the faith.
3 hours ago, Rez77 said:We should have clinical application of something that is better than 70 percent improvement by 2080. Don't know how old you guys are but if you can make it to then another 60 years you should be able to get the work done. Though there will not be any significant anti-aging technologies till 3200 so unfortunately you will only be able to achieve "scarless" healing of much older aged skin. Keep the faith.
I understand the pessimistic attitude considering there hasn't been much advancements in scarring from say 2000 to current times. However, now that we are starting to use stem cell research I remain optimistic that we will move at a faster pace. For example, we just recently discovered the cure for Hepatitis C.