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[Sticky] Scarless Healing

 
MemberMember
12
(@hydrogel)

Posted : 07/03/2015 3:53 am

 

I think I posted this a while back, but here's a reminder: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996784/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937506/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937507/ Long story short, there's a new combination of treatment methods that's been going around and is very promising. It's readily available because it's just a combination of established methods, and it's cheap. Read up on these links, talk to your dermatologist of choice, and enjoy. Figured you guys would jump at this rather than wait God knows how long for new science to break way.

 

 

This is fantastic and will likely work for some. Unfortunately, probably won't do much for ice picks and scarred pores (my issue). :0( Thanks for sharing ;0)

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MemberMember
24
(@jackdoe)

Posted : 07/03/2015 7:55 am

I tried subcision, but I didn't put a needle deep under the skin, that's why I didn't get a noticeable improvement. I'd like to go deeper, but now I'm afraid to damage the fat layer, because I will be need in full thickness excision then...

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MemberMember
68
(@rudy1986)

Posted : 07/03/2015 8:23 am

So you think atrophic scar dont go to fat layer roach?

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MemberMember
24
(@jackdoe)

Posted : 07/03/2015 8:33 am

Yeah, I do. But I judge by my case. Cheeks have more thicker skin than other parts in a face. Temples and forhead may get a deeper damage.

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MemberMember
3
(@roboricky)

Posted : 07/03/2015 9:48 am

 

I tried subcision, but I didn't put a needle deep under the skin, that's why I didn't get a noticeable improvement. I'd like to go deeper, but now I'm afraid to damage the fat layer, because I will be need in full thickness excision then...

 

 

If you're referring to the studies I posted, it's actually quite a bit more than just subcision. It's a combination of that, TCA, and microneedling in a very particular order and fashion. They have all the details (exactly how deep they went) in the studies.

 

P.S. No offense to anyone, but try to take what Rudy says with a grain of salt. ;)

 

 

 

 

 

I think I posted this a while back, but here's a reminder: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996784/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937506/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937507/ Long story short, there's a new combination of treatment methods that's been going around and is very promising. It's readily available because it's just a combination of established methods, and it's cheap. Read up on these links, talk to your dermatologist of choice, and enjoy. Figured you guys would jump at this rather than wait God knows how long for new science to break way.

 

 

This is fantastic and will likely work for some. Unfortunately, probably won't do much for ice picks and scarred pores (my issue). :0( Thanks for sharing ;0)

 

 

You should see some improvement (more than any other treatment available right now, more than likely) as long as you undergo all of the treatments as outlined in the first study. Each study exercises a bit of variety, but the first study appears to have found the most effective combination of treatment methods. The African American man in the first study saw quite a bit of improvement in his icepick scarring. Besides that, many cases of rolling and boxcar scars were completely healed. Pretty cool. Really look over those studies, especially the first one. There's a lot of cool stuff in there.

 

Hope I helped!

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MemberMember
68
(@rudy1986)

Posted : 07/03/2015 11:13 am

Dont you guys be tricked, rez77 is in disquise somewhere under different nick :)

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MemberMember
24
(@jackdoe)

Posted : 07/04/2015 6:37 am

Okay, I'm gonna give the papers to the doc on Monday. Before that I wanna ask your opinion about:1) adding hyaluronic acid and CAR-decorin in the hydrogel2) injections of copper peptides, hyaluronic acid and CAR-decorin around the woundAlso, give me your answers to these questions (based on your opinion or scientific facts):1) when should I start to inject CAR-DCN and how often should I inject it?2) when should I start to inject HA and how often should I inject it?3) when should I start to inject GHK and how often should I inject it?Please don't ignore this message.

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MemberMember
68
(@rudy1986)

Posted : 07/04/2015 11:12 am

Roach, my reply here is simple..

 

Try to focus on hydrogel, nothing more.

 

You might reduce or even negate the real power of hydrogel itself

 

 

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MemberMember
11
(@kim6288)

Posted : 07/04/2015 3:14 pm

I read this and in this study they have achieved scarless healing with the pulsed electrical currents. Docs are also using this type of electrical therapy to destroy tumors they go in with a needle probe or you wear the magnetic therapy probes on your head all day to destroy a brain tumor. Pulsed electrical machines are for sale but I think the type they used in the scarless healing study are more powerful voltage and so only used in the clinical setting. I wonder if at the strength they used if it is painful and you need anesthesia. They definitely achieved scarless healing according to the article

 

 

 

Here's another article about electrical currents regenerating skin:

 

http://www.bizjournals.com/boston/blog/health-care/2015/06/mgh-researchers-use-common-technology-to.html

 

œYou stick your finger in a fire, you burn it and get a scar. With this you don™t end up with scarring, said Dr. Martin Yarmuch, director of the MGH Center for Engineering in Medicine and one of the researchers. œThat™s the key here. From an academic standpoint, it™s interesting to observe it. From an application standpoint, you get scar-less results.

 

Specifically the technology is called 'pulsed electrical fields' for anyone interested.

 

I've never seen a study this optimistic about electricity being used for scarring. Add this to the growing list of treatments that would be non-invasive, probably very cheap, and with the potential t

 

 

heal skin without scarring. I'm going to look up the paper that this article refers to.

 

 

 

Here's a quote on the same story, different article: ( http://www.massgeneral.org/about/pressrelease.aspx?id=1822 )

"Our results show that the procedure is safe, does not lead to scarring and increases skin metabolism and cell proliferation, says Martin Yarmush, MD, PhD, director of the MGH Center for Engineering in Medicine and corresponding author of the paper. œWe now need to investigate the impact of PEF treatment on aged skin, as well as on skin with other forms of damage, and we are looking for funding to help us design, build and test a device for clinical application.

 

I hope someone funds them :)

 

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MemberMember
29
(@cycloverid)

Posted : 07/04/2015 4:57 pm

While the tests were a success at achieving scarless results, they were done on 6 week old rats, or the equivalent of 5 year old humans. They have yet to prove that this works on adults.

 

I've found the paper:

http://www.nature.com/srep/2015/150512/srep10187/full/srep10187.html

 

It describes exactly what settings they used!

"The figure shows the electro-thermal model when the applied PEF protocol was 500V, 70s pulse duration, and 200 pulses delivered at 3Hz."

 

In the paper they mention that they need to make changes to the machine. "However translation of the method to humans will require further studies and device development, in which pain reduction is necessary"

 

At the end of the paper they claim: "Our results suggest that PEF can significantly improve skin function and rejuvenation."

 

That's awesome!

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MemberMember
24
(@jackdoe)

Posted : 07/05/2015 3:13 am

Mate, we already discussed it. I like this treatment.

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MemberMember
29
(@cycloverid)

Posted : 07/05/2015 4:40 pm

Ah, cool. Didn't notice it. Hopefully something comes of this research!

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MemberMember
14
(@bloodwar44)

Posted : 07/06/2015 11:04 am

http://www.tandfonline.com/doi/abs/10.3109/03639049109057311#preview

 

Dextran hydrogel formula, buy the paper and show your doctor roach

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MemberMember
24
(@jackdoe)

Posted : 07/06/2015 11:21 am

http://www.tandfonline.com/doi/abs/10.3109/03639049109057311#preview

 

Dextran hydrogel formula, buy the paper and show your doctor roach

 

Nice. Thank you, bloodwar44.

 

Btw, I didn't reach the doc, because he changed his workplace. I'm looking for his new workplace.

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MemberMember
21
(@repola)

Posted : 07/07/2015 5:28 am

 

 

It is a good option to get a great improvement.

 

Something real, no bullshit.

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MemberMember
24
(@jackdoe)

Posted : 07/07/2015 7:14 am

If I cook the hydrogel inside my country will it be a patent infringement?

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MemberMember
68
(@rudy1986)

Posted : 07/07/2015 9:04 am

No, theres no lawsuit, try it on roach. If it produce scar free healing, you will be Bill Gates 2.0

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MemberMember
24
(@jackdoe)

Posted : 07/07/2015 9:08 am

Okay, thank you. I found the new workplace of the doc. I'm gonna reach him tomorrow.

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MemberMember
24
(@jackdoe)

Posted : 07/07/2015 11:57 am

Also, what do you guys think about a size of an excision? I think if I treat scar by scar then my face will look uneven anyway. The scars are close together. I can't say the same about bigger excisions, that will treat multiple scars. Part by part about 3cm x 3cm or narrower - 3 cm x 1-1.5 cm.

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MemberMember
68
(@rudy1986)

Posted : 07/07/2015 8:08 pm

If your scar is close , then excise them all.. see if it produce scar free

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MemberMember
24
(@jackdoe)

Posted : 07/08/2015 3:13 am

I gave all the papers to the doc. Now I'm waiting for his message or call.

 

He promised me that he will read all the papers and contact me after. It was a big stack of the papers, so it will take time to read that. Let's hope for best.

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MemberMember
68
(@rudy1986)

Posted : 07/08/2015 5:33 am

What paper did you give him?

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MemberMember
24
(@jackdoe)

Posted : 07/08/2015 5:36 am

Seabs summary, all the DEX papers, CAR-Decorin papers, GHK papres, and electric fields papers.

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MemberMember
24
(@jackdoe)

Posted : 07/08/2015 8:08 am

Damn, I'm very worried.

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MemberMember
11
(@kim6288)

Posted : 07/08/2015 8:26 pm

they are using it on humans to destroy cancer cells without destroying the cells around it. It works but like everything else they will keep it from us

While the tests were a success at achieving scarless results, they were done on 6 week old rats, or the equivalent of 5 year old humans. They have yet to prove that this works on adults.

I've found the paper:
http://www.nature.com/srep/2015/150512/srep10187/full/srep10187.html

It describes exactly what settings they used!
"The figure shows the electro-thermal model when the applied PEF protocol was 500V, 70s pulse duration, and 200 pulses delivered at 3Hz."

In the paper they mention that they need to make changes to the machine. "However translation of the method to humans will require further studies and device development, in which pain reduction is necessary"

At the end of the paper they claim: "Our results suggest that PEF can significantly improve skin function and rejuvenation."

That's awesome!

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