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[Sticky] Scarless Healing

 
0
(@Anonymous)

Posted : 06/05/2015 10:27 pm

2030? I don't think it will be that far in the future... I honestly feel like within the next year or two there will be human trials for the hydrogel...at least I hope so.

When does everyone else think this hydrogel will be available?

 

I also hope that the hydrogel can completely regenerate the dermis and epidermis in humans, otherwise all of this waiting was pointless.

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(@jackdoe)

Posted : 06/06/2015 12:32 am

I think so. I'm sure the hydrogel will work. At least it will regenerate the dermis. And also they can add other stuff to make it work better.

 

Seabs, I read a lot of your posts and the PDF and understood many things. Thank you))

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68
(@rudy1986)

Posted : 06/06/2015 12:53 am

Seabs is the leading people in this forum...

 

He is always optimist, thats what make us happy actually :)

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101
(@lapis-lazuli)

Posted : 06/06/2015 5:39 am

2030? I don't think it will be that far in the future... I honestly feel like within the next year or two there will be human trials for the hydrogel...at least I hope so.

 

It says on Gemstone Therapeutics's website that human trials for the hydrogel are scheduled for 2016.

 

Girls will most likely avoid boys with scars in most cases. You may say to cheer us up, but reality is reality. Girls despise boys with scars

 

While it is true that a lot of women lose interest in dating men who have physical imperfections there are also oodles of women for whom physical imperfection isn't a dealbreaker. But this is something you have to find out for yourself. It's like I can tell you the Eiffel tower is in Paris but in your case you have to see it with your own eyes before you believe it.

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(@rudy1986)

Posted : 06/06/2015 9:41 am

http://www.baltimoresun.com/business/bs-bz-gemstone-biotherapeutics-20150605-story.html

 

Gemstone wins for more investment as the best md at baltimore

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68
(@rudy1986)

Posted : 06/06/2015 11:21 am

Lapiz, do you think it will be in our lifetime bout scarfree healing?

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24
(@jackdoe)

Posted : 06/07/2015 4:16 am

http://www.lotioncrafter.com/decorinyl.html

 

What if use this stuff instead of decorin?

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(@jackdoe)

Posted : 06/07/2015 7:27 am

Seabs, answer to my question, please:

 

What do you think about adding other stuff to the hydrogel? For example, hyaluronic acid, copper peptides, decorinyl. And also, what if I inject this stuff around a wound every day after applying of the hydrogel?

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14
(@bloodwar44)

Posted : 06/07/2015 2:26 pm

Seabs, answer to my question, please:

 

What do you think about adding other stuff to the hydrogel? For example, hyaluronic acid, copper peptides, decorinyl. And also, what if I inject this stuff around a wound every day after applying of the hydrogel?

seabs doesn't have the answer to your question

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11
(@2001)

Posted : 06/07/2015 4:28 pm

JHU should refine the hydrogel using only porcine models for the tests until they get the results they got from that mice test. I don't want to hear things like "stem cells". You have no idea how much trouble is involved to get them, both in cost and application. The hydrogel worked on mice it will work on pigs and humans. They need to sort out what changes need to be made to Hydrogel in order to reach that solution. The roadblock wont be passed until they succeed in achieving the same scarfree results in the porcine model. Hopefully they care enough to keep doing tests with the gel on the porcine models to see if a ratio change yields the scarfree answer.

 

 

this is why our fda regulated drug industry is so screwed. there should be laws in place to let them test other ratios/formulas on the pigs, since it didn't give them the same result they got in the mice. going back to the mice again and moving forward is stupid. the real challenge is the pigs right now. they need to keep tampering with the gel on these pigs before moving forward to humans. We are so damn close to curing scars, and it's a depressing blow when the new suddenly goes south like this.

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73
(@seabs135)

Posted : 06/07/2015 4:55 pm

Roach, this answer might annoy you, if so I dont mean to btw... I dont think anything of it. Rhetorically what do you think about adding perfume to a tulip?
The science states it degraded fast and got complete regeneration; maybe adding something would adjust it.and deplete it?
The recent paper was a technical comparison, and nothing has been defined and debunked...

Seabs, answer to my question, please:

What do you think about adding other stuff to the hydrogel? For example, hyaluronic acid, copper peptides, decorinyl. And also, what if I inject this stuff around a wound every day after applying of the hydrogel?

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24
(@jackdoe)

Posted : 06/08/2015 3:43 am

I believe in 3 things for "Scar free" wound healing right now.

Egg oil (with intact proteins)

Hydrogel

The Phenol Vit A Vit D lotion combo

 

Do you still believe in 1st and 3rd solutions?

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68
(@rudy1986)

Posted : 06/08/2015 8:58 am

I suspect people who had scarred would not be able to return their skin back since the cell's dna has already forgotthen its original form

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24
(@jackdoe)

Posted : 06/08/2015 11:14 am

Take it easy, Rudy. It's just depression. Sometimes I feel that way and I find a thousand reasons why I won't get my skin back. We all need to relax.

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12
(@hydrogel)

Posted : 06/08/2015 5:29 pm

Hey team,

 

It seems there is a great deal of potential with Gemstone's biosynthetic scaffold to initiate scarless healing in both acute and chronically scarred dermal tissue. Additionally, Gemstone is getting a great deal of attention from investors: http://www.baltimoresun.com/business/bs-bz-gemstone-biotherapeutics-20150605-story.html - hopefully the additional funding will speed up trials. A real viable solution could be around the corner. My only concern at the moment is that Gemstone may not be considering or interested in the potential "cosmetic" applications of the hydrogel. Similar to Avita Recell, the focus seems to be on urgent and chronic wound care.

 

1. Is there any information or evidence suggesting Gemstone's hydrogel COULD be used for the cosmetic treatment of dermatological problems such as acne scarring?

 

2. Has any member of the Acne.org community reached out to Gemstone Biotherapeutics to inquire about the hydrogel's potential use for cosmetic use? If not, this may be a good idea. I would recommend a group of us draft a document expressing our questions and concerns, then find a way to advance that document to a reputable member of Gemstone Biotherapeutics. Thus, we may be able to get the answers we need instead of simply speculating. Again, this is unless someone here can produce a tangible document released by Gemstone alluding to the hydrogel's use for cosmetic purposes.

 

Thanks!

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68
(@rudy1986)

Posted : 06/08/2015 10:14 pm

http://www.realself.com/question/los-angeles-ca-scarless-healing

 

Seeing those professionals' answers make me down really. It is coming from the mouth of a highly professional individuals..

 

They are stating we are still too far off

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24
(@jackdoe)

Posted : 06/09/2015 12:07 am

I'm pretty sure they don't even know about DH and other things beeing worked on.

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(@jackdoe)

Posted : 06/09/2015 3:55 am

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623574/pdf/wound.2011.0299.pdf

 

They state that it is more effective than native decorin.

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101
(@lapis-lazuli)

Posted : 06/09/2015 7:48 am

Hey team,

 

It seems there is a great deal of potential with Gemstone's biosynthetic scaffold to initiate scarless healing in both acute and chronically scarred dermal tissue. Additionally, Gemstone is getting a great deal of attention from investors: http://www.baltimoresun.com/business/bs-bz-gemstone-biotherapeutics-20150605-story.html - hopefully the additional funding will speed up trials. A real viable solution could be around the corner. My only concern at the moment is that Gemstone may not be considering or interested in the potential "cosmetic" applications of the hydrogel. Similar to Avita Recell, the focus seems to be on urgent and chronic wound care.

 

1. Is there any information or evidence suggesting Gemstone's hydrogel COULD be used for the cosmetic treatment of dermatological problems such as acne scarring?

 

2. Has any member of the Acne.org community reached out to Gemstone Biotherapeutics to inquire about the hydrogel's potential use for cosmetic use? If not, this may be a good idea. I would recommend a group of us draft a document expressing our questions and concerns, then find a way to advance that document to a reputable member of Gemstone Biotherapeutics. Thus, we may be able to get the answers we need instead of simply speculating. Again, this is unless someone here can produce a tangible document released by Gemstone alluding to the hydrogel's use for cosmetic purposes.

 

Thanks!

 

I don't get what you mean seeing that the end result of being treated with something that enables the skin to regenerate is regenerated skin. So you wouldn't need cosmetic surgery after treatment.

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68
(@rudy1986)

Posted : 06/09/2015 8:20 am

Clinical trials takes grnerally 15 fucking years..

 

Damned time wasting

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(@cycloverid)

Posted : 06/09/2015 8:32 am

...An injectable that is supposed to promote regeneration. And this one is specifically targeted at skin. They also compare it to hydrogel but I assume this is not the same one that Gemstone is working on. Like hydrogel it looks to be easy to derive chemically.

 

"The geometry of the MAP gel networks entices cells to migrate into the gel without the need for anything other than a cell adhesive peptide, so that the cells can grab onto the gels."

 

http://phys.org/news/2015-06-gel-wounds-tissue-regeneration.html

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101
(@lapis-lazuli)

Posted : 06/09/2015 9:11 am

Clinical trials takes grnerally 15 fucking years..

 

Damned time wasting

 

Obviously a certain amount of time is needed to verify that something is safe to use... Perhaps the process can be sped up but neither you nor I can make any real statements about that as we don't know enough about it.

 

A lot of people are working very hard every day to achieve something. I see this also in the hospital I work in. These people are working very hard, OK? All these negative comments from people like us aren't what they deserve.

 

 

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68
(@rudy1986)

Posted : 06/09/2015 9:41 am

Lapis, why is George Davis of gemstone willing to invest 15 yers of testing? Isnt he old enough?

 

Sorry for my comments though.. i am feeling lonely, sad, desperate, anger, and suicidal at this point

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5
(@skinregenerator)

Posted : 06/09/2015 10:05 am

Lapis, why is George Davis of gemstone willing to invest 15 yers of testing? Isnt he old enough?

 

Sorry for my comments though.. i am feeling lonely, sad, desperate, anger, and suicidal at this point

I guess he has no answer for this

 

...An injectable that is supposed to promote regeneration. And this one is specifically targeted at skin. They also compare it to hydrogel but I assume this is not the same one that Gemstone is working on. Like hydrogel it looks to be easy to derive chemically.

 

"The geometry of the MAP gel networks entices cells to migrate into the gel without the need for anything other than a cell adhesive peptide, so that the cells can grab onto the gels."

 

http://phys.org/news/2015-06-gel-wounds-tissue-regeneration.html

right, it's not the same gel

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24
(@jackdoe)

Posted : 06/09/2015 10:11 am

Sorry for my comments though.. i am feeling lonely, sad, desperate, anger, and suicidal at this point

 

I can feel you. That's why I'm gonna do it in the near future. Neck or nothing...

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