Rudy, explain it to me please. I don't got what you meant. What is the rete ridges and how it can make the scar invisible? I'm sorry, as I said before, I'm not a native speaker and it's hard to understand to me...
P.S. Even if a scar will be flat, how about the texture and color? It may be shiny, white or red...
Masson's trichrome:
http://en.wikipedia.org/wiki/Masso n's_trichrome_stain
Also from Wikipedia:
Rete ridges ("rete tips") are epidermal thickenings that extend downward between dermal papillae.
as answered above roach.
Lapiz, what do you think of their latest post at facebook?
Masson's trichrome: http://en.wikipedia.org/wiki/Masso n's_trichrome_stain
Also from Wikipedia:Rete ridges ("rete tips") are epidermal thickenings that extend downward between dermal papillae.
so tired, just when i thought it would work..stp ...
it failed
Why do from time to time some people feel the need to say that the hydrogel that's still being worked on has failed?
Is it to startle the people who are following this thread for updates? Is it a way to release negative energy? Is it just the need to bitch and moan? Is it a cry for attention? Is it so-called troll behavior? Is it a way to fight boredom? Or is it so that there's just no reason at all?
Either way, it's stupid and it should stop. In my opinion.
I don't know which PDF you are referring to but the hydrogel hasn't "failed". It is just being looked at right now what potential it has.
just like Yuvista
I dont get it why people here said hydrogel failed. Fail = not scar free healing in human.
i was blinded by optimism
Dude, we don't know how it heals the dermis. It didn't completely regenerate the full-thickness skin, but it can regenerate the dermal layer where acne scars are.
Acne scars are the result of inflammation within the dermal layer of skin...
Pimple is an inflammation of a hair follicle. Hair follicles are basing in the dermis.
It doesn't damage the fat layer. Maybe only in rare cases. Probably we don't even need to excise the full dermis. Just only three quarters (3/4). In that case hair follicles will remain. I think it's important, because they produce stem cells.
My scars look like normal tissue, but they are indented or raised. It means that the upper layers of the skin are OK. There are blood vessels, nerves, and hair follicles. The lower layers seem to be OK as well, because my hair follicles are alive. So, what do I wanna say? There is not so much scar tissue under pitted scars. In fact, there is loss of collagen. We just need to regrow new collagen. IMO.
Phew, I hope that you got me. It was hard to say with my English))
I got the PDF, if anyone interested.
https://drive.google.com/file/d/0BwZi6M9K30AqMWp6ektFaElhUHM/view?usp=sharing
I got the PDF, if anyone interested.
https://drive.google.com/file/d/0BwZi6M9K30AqMWp6ektFaElhUHM/view?usp=sharing
Thank you for posting that, Roach. It's a very interesting read.
Although the wound-healing process is well-studied field, much knowledge must be gained to unlock the door to the regenerative pathway in humans. Studies on finding new dermal substitutes and studies on the positive effect of AF and HA on 76 wound-healing process are two different ways of gaining insight that may lead to improved wound healing for the patient.
The above is from the PDF. It seems they think the gelatin spheres can improve the visual appearance of scars. Which is promising.
Although the wound-healing process is well-studied field, much knowledge must be gained to unlock the door to the regenerative pathway in humans. Studies on finding new dermal substitutes and studies on the positive effect of AF and HA on 76 wound-healing process are two different ways of gaining insight that may lead to improved wound healing for the patient.
The above is from the PDF. It seems they think the gelatin spheres can improve the visual appearance of scars. Which is promising.
three D almost is always better than 2D structure for tissue engineering
Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel
That's what I'm talking about. But anyways, I wanna complement it with other regenerative stuff. For example, GHK-Cu or CACIPLIQ 20 and so on. Hydrogel is good for vascularization, but also we need to reduce TGF B production. Does the hydrogel do it?
I'll print the recent PDF and then I'm going to show the papers to the doc.
Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel
That's what I'm talking about. But anyways, I wanna complement it with other regenerative stuff. For example, GHK-Cu or CACIPLIQ 20 and so on.
How about stp705 of Sirnaomics?
I never heard of them. It would be great if you give me some links))