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[Sticky] Scarless Healing

 
MemberMember
68
(@rudy1986)

Posted : 05/27/2015 8:49 am

Hell i will take it anytime as long as rete ridges was similar to my healthy skin when observed with mason's trichomme.

 

even sun wouldnt able to tell if it is a scar

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MemberMember
24
(@jackdoe)

Posted : 05/27/2015 11:25 am

Rudy, explain it to me please. I don't got what you meant. What is the rete ridges and how it can make the scar invisible? I'm sorry, as I said before, I'm not a native speaker and it's hard to understand to me...

 

P.S. Even if a scar will be flat, how about the texture and color? It may be shiny, white or red...

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MemberMember
101
(@lapis-lazuli)

Posted : 05/27/2015 12:01 pm

Masson's trichrome:

 

http://en.wikipedia.org/wiki/Masso n's_trichrome_stain

 

Also from Wikipedia:

 

Rete ridges ("rete tips") are epidermal thickenings that extend downward between dermal papillae.

 

 

:banana:

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JackDoe, JackDoe and JackDoe reacted
MemberMember
68
(@rudy1986)

Posted : 05/27/2015 12:13 pm

as answered above roach.

 

Lapiz, what do you think of their latest post at facebook?

 

Masson's trichrome: http://en.wikipedia.org/wiki/Masso n's_trichrome_stain

Also from Wikipedia:Rete ridges ("rete tips") are epidermal thickenings that extend downward between dermal papillae. :banana:

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MemberMember
101
(@lapis-lazuli)

Posted : 05/27/2015 1:41 pm

It's promising. I'm just curious to see what they'll ultimately achieve.

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MemberMember
68
(@rudy1986)

Posted : 05/28/2015 6:57 am

so tired, just when i thought it would work..stp ...

it failed

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MemberMember
101
(@lapis-lazuli)

Posted : 05/28/2015 9:53 am

so tired, just when i thought it would work..stp ...

it failed

 

Why do from time to time some people feel the need to say that the hydrogel that's still being worked on has failed?

 

Is it to startle the people who are following this thread for updates? Is it a way to release negative energy? Is it just the need to bitch and moan? Is it a cry for attention? Is it so-called troll behavior? Is it a way to fight boredom? Or is it so that there's just no reason at all?

 

Either way, it's stupid and it should stop. In my opinion.

 

 

 

 

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Julian1, bloodwar44, Julian1 and 3 people reacted
MemberMember
68
(@rudy1986)

Posted : 05/28/2015 10:13 am

Lapiz, i dont mean it like that, but see with your own eyes. Hydrogel clearly failed based on the pdf i bought earlier

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MemberMember
101
(@lapis-lazuli)

Posted : 05/28/2015 10:55 am

I don't know which PDF you are referring to but the hydrogel hasn't "failed". It is just being looked at right now what potential it has.

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MemberMember
24
(@jackdoe)

Posted : 05/28/2015 11:51 am

I dont get it why people here said hydrogel failed. Fail = not scar free healing in human.

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MemberMember
68
(@rudy1986)

Posted : 05/28/2015 11:54 am

I don't know which PDF you are referring to but the hydrogel hasn't "failed". It is just being looked at right now what potential it has.

just like Yuvista

 

 

I dont get it why people here said hydrogel failed. Fail = not scar free healing in human.

i was blinded by optimism

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MemberMember
24
(@jackdoe)

Posted : 05/29/2015 3:20 am

Dude, we don't know how it heals the dermis. It didn't completely regenerate the full-thickness skin, but it can regenerate the dermal layer where acne scars are.

 

Acne scars are the result of inflammation within the dermal layer of skin...

 

Pimple is an inflammation of a hair follicle. Hair follicles are basing in the dermis.

 

8912.jpg

 

It doesn't damage the fat layer. Maybe only in rare cases. Probably we don't even need to excise the full dermis. Just only three quarters (3/4). In that case hair follicles will remain. I think it's important, because they produce stem cells.

 

My scars look like normal tissue, but they are indented or raised. It means that the upper layers of the skin are OK. There are blood vessels, nerves, and hair follicles. The lower layers seem to be OK as well, because my hair follicles are alive. So, what do I wanna say? There is not so much scar tissue under pitted scars. In fact, there is loss of collagen. We just need to regrow new collagen. IMO.

 

Phew, I hope that you got me. It was hard to say with my English))

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MemberMember
68
(@rudy1986)

Posted : 05/29/2015 6:21 am

I hope so Roach, btw atrophic scar destroys the dermis below

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MemberMember
24
(@jackdoe)

Posted : 05/29/2015 7:34 am

Sebaceous glands are found in the upper layers of the dermis. I think the main damage is right there.

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MemberMember
101
(@lapis-lazuli)

Posted : 05/29/2015 8:36 am

Through our struggles we are slowly becoming dermatologists.

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JackDoe, rudy1986, JackDoe and 3 people reacted
MemberMember
24
(@jackdoe)

Posted : 05/29/2015 1:49 pm

I got the PDF, if anyone interested.

 

https://drive.google.com/file/d/0BwZi6M9K30AqMWp6ektFaElhUHM/view?usp=sharing

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MemberMember
101
(@lapis-lazuli)

Posted : 05/29/2015 2:36 pm

 

Thank you for posting that, Roach. It's a very interesting read.

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MemberMember
101
(@lapis-lazuli)

Posted : 05/29/2015 3:03 pm

Although the wound-healing process is well-studied field, much knowledge must be gained to unlock the door to the regenerative pathway in humans. Studies on finding new dermal substitutes and studies on the positive effect of AF and HA on 76 wound-healing process are two different ways of gaining insight that may lead to improved wound healing for the patient.

The above is from the PDF. It seems they think the gelatin spheres can improve the visual appearance of scars. Which is promising.

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MemberMember
5
(@skinregenerator)

Posted : 05/29/2015 5:27 pm

Although the wound-healing process is well-studied field, much knowledge must be gained to unlock the door to the regenerative pathway in humans. Studies on finding new dermal substitutes and studies on the positive effect of AF and HA on 76 wound-healing process are two different ways of gaining insight that may lead to improved wound healing for the patient.

 

 

The above is from the PDF. It seems they think the gelatin spheres can improve the visual appearance of scars. Which is promising.

 

 

 

 

 

 

 

 

three D almost is always better than 2D structure for tissue engineering

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MemberMember
68
(@rudy1986)

Posted : 05/29/2015 7:47 pm

Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel

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MemberMember
24
(@jackdoe)

Posted : 05/30/2015 12:15 am

Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel

That's what I'm talking about. But anyways, I wanna complement it with other regenerative stuff. For example, GHK-Cu or CACIPLIQ 20 and so on. Hydrogel is good for vascularization, but also we need to reduce TGF B production. Does the hydrogel do it?

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MemberMember
68
(@rudy1986)

Posted : 05/30/2015 12:19 am

 

Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel

That's what I'm talking about. But anyways, I wanna complement it with other regenerative stuff. For example, GHK-Cu or CACIPLIQ 20 and so on.

How about stp705 of Sirnaomics?

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MemberMember
24
(@jackdoe)

Posted : 05/30/2015 12:24 am

I'll print the recent PDF and then I'm going to show the papers to the doc.

 

 

Maybe if we excised our acne scars, complete regeneratiom could occur even with standard hydrogel

That's what I'm talking about. But anyways, I wanna complement it with other regenerative stuff. For example, GHK-Cu or CACIPLIQ 20 and so on.

How about stp705 of Sirnaomics?

I never heard of them. It would be great if you give me some links))

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MemberMember
101
(@lapis-lazuli)

Posted : 05/30/2015 3:05 am

I never heard of them. It would be great if you give me some links))

 

It was mentioned very recently by me. You remember the bold statement?

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MemberMember
68
(@rudy1986)

Posted : 05/30/2015 3:19 am

Lapiz, they say it can regenerate skin morphology with HF

 

It is great

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