Nice before and after pic of recell. Costs 2500 pounds in UK I think..
http://www.ukcosmeticclinic.co.uk/Recell-spray-on-skin-in-Kings-Lynn-and-Peterborough
The lighting is different.
http://www.sciencedirect.com/science/article/pii/S0142961212013348
Abstract
Scar inhibition of dermal equivalent is one of the key issues for treatment of full thickness skin defects. To yield a bioactive RNAi functionalized matrix for skin regeneration with inhibited scarring, collagen-chitosan/silicone membrane bilayer dermal equivalent (BDE) was combined with trimetylchitosan (TMC)/siRNA complexes which could induce suppression of transforming growth factor-1 (TGF-1) pathway. The RNAi-BDE functioned as a reservoir for the incorporated TMC/siRNA complexes, enabling a prolonged siRNA release. The seeded fibroblasts in the RNAi-BDE showed good viability, internalized the TMC/siRNA complexes effectively and suppressed TGF-1 expression constantly until 14 d. Application of the RNAi-BDE on the full-thickness skin defects of pig backs confirmed the in vivo inhibition of TGF-1 expression by immunohistochemistry, real-time quantitative PCR and western blotting during 30 d post surgery. The levels of other scar-related factors such as collagen type I, collagen type III and -smooth muscle actin (-SMA) were also down-regulated. In combination with the ultra-thin skin graft transplantation for 73 d, the regenerated skin by RNAi-BDE had an extremely similar structure to that of the normal one. Our study reflects the latest paradigm of tissue engineering by incorporating the emerging biomolecule siRNA. The 3-D scaffolding materials for siRNA delivery may have general implications in generation of bioactive matrix as well.
I will show you guys the recent abstract of scar free healing
I will show you guys the recent abstract of scar free healing
At the end of page 58 they seem to say that the results they achieved was a dermis that had a normal architecture after treatment with "gelatin spheres". That's interesting. I'll read the whole thing later on. Thanks for posting.
I dont get it why people here said hydrogel failed. Fail = not scar free healing in human.
seeing regenerative response, they could've just accelerate it to human Like what they are doing right now.
Rete ridges are rarely regenerates in scar, if any.
thats sign of regeneration
Porcine wound healing is considered to be most similar to that of humans and as a translational model, pigs display the greatest concordance with human trials. First, porcine skin most closely resembles human skin both anatomically and physiologically. Both have similar dermal-epidermal thickness ratio and dermal vascularization pattern. Biochemically, porcine and human skins have similar collagen matrix and keratinous proteins. Studies have also shown an excellent agreement between pig and human with respect to wound healing responses from growth factors.
Just because of that.
Anyhow, I believe that it can regenerate dermal wounds. Scar by scar. The most noticeable in the first place, next time another ones. It's impossible to cut your whole cheek out and regenerate it.
There has been an announcement on the gemstone Facebook page.
"Positive results from recently completed study of our Biosynthetic Wound Therapeutic approved for a pending publication in the Journal of Investigative Dermatology."
That sounds promising. I will keep track of it.
they call that positive?
What exactly are they referring to according to you? Which results are they referring to which you wouldn't describe as positive?