Acne.org Products
You must have accidentally copied the edit post above his actual post. No harm! Anyone who tries the saliva let me know. I wonder if it could be mixed with aloe vera gel?
Ya,can it be mixed with something??Cos saliva stinks sometimes.And how does one produce that much saliva???
I have high hopes after reading about acell on this thread. I have a couple concerns though. Is this really coming out as soon as well all are thinking? Within the next month?? Also, it seems like many cash hungry derms and surgeons would be upset because all other scar removal methods would be inferior and they would lose money. Also, the whole method of removing the scar. Most scars, except the very superficial ones extend past the dermis into the fat layer, even rolling scars which people tend not to think are very deep, are actually a result of fat missing fairly deep down. I am curious whether this could all be cut out and healed without a scar. Anyone with any thoughts or answers to my questions, please chime in.
Been a long time...
I've still been looking at Acell as a possibility for myself too. I have stretch marks on my hips and arms as well as some fairly shallow acne scarring on my cheeks. I do not think people with ice pick scarring will really benefit from this treatment seeing as how there is no longer any skin to wound. Almost all other forms of scarring will most likely be removable/ healable. I know I may sound pessimistic towards everyone with the ice picks, but I honestly don't see a way unless the whole section of your face is cut out and treated with Acell. Hey, if you're willing to go through with that, more power to you. Good luck. I'm just planning on following some peels with Acell on my scars and I have heard wonderful things. I can't wait to try it later this year hopefully...
Is there anywhere I can get more information on this Acell thing? What is it exactly? Is there a separate thread for it? Do they have a website? What is it???? You guys have me super excited right now because I don't have any icepick or indented type scarring so maybe it could help me. I would love to find more info.
Is there anywhere I can get more information on this Acell thing? What is it exactly? Is there a separate thread for it? Do they have a website? What is it???? You guys have me super excited right now because I don't have any icepick or indented type scarring so maybe it could help me. I would love to find more info.
This toppic has already been discussed in this thread. Please read this thread from the beginning. I know it is very long, but it is worth to read.
You can also look at these pages:
http://www.abclocal.go.com/ktrk/story?sect...&id=6216619
http://www.dailymail.co.uk/sciencetech/art...FOUR-weeks.html
Also a big topic in this forum(use search function:
http://www.hairsite.com/hair-loss/forum_en...ast_answer.html
Right, I've seen all of that stuff before in the news and such. Does Acell plan to bring this into commercial use for the treatment of scars? How will this end up working for us? I guess I understand the big picture but how can we use it? That's what I was really getting at in my question. Are there plans to use it for scarring? Is this stuff going to be available without a doctor or how does it work?
Right, I've seen all of that stuff before in the news and such. Does Acell plan to bring this into commercial use for the treatment of scars? How will this end up working for us? I guess I understand the big picture but how can we use it? That's what I was really getting at in my question. Are there plans to use it for scarring? Is this stuff going to be available without a doctor or how does it work?
Hi hoursafter. Acell would be available in july for the US, you can get it through a doctor. As for your other question on whether acell can be use for the commercial treatment of scars, it is highly likely that it can be used for it. The military is already conducting trial tests on using acell to grow back fingers, muscle tissue and even burnt skin. You can get a better idea from viewing this video:
If this is really going to happen its amazing. There will no longer be a need for this forum!!! I honestly can't believe it, feels so unreal that scarring, something which has affected humans forever will be eliminated. I mean a month away from release i can hardly contain myself.
If this is really going to happen its amazing. There will no longer be a need for this forum!!! I honestly can't believe it, feels so unreal that scarring, something which has affected humans forever will be eliminated. I mean a month away from release i can hardly contain myself.
Don't you think that this is a bit to early to be such enthusiastic? I'm also confident concerning the acell thing, but till now nobody has eliminated acne scars with it. I've read in one forum about complete elimination of stretch marks with acids+acell but another user has failed to erase his pitted acne scars with the same method. I think he failed, because he didn't remove the scar tissue completely, which is deeper than stretch marks. But how can you reach complete scar tissue erasing?
No serious doctor today would risk to cut out the scar and put acell on it in the hope that no new scar will develop. I think there is a lot of research to do in connection with acne scars+acell. Maybe someday it will be possible but don't think it will go such fast 
. Another point is that acell did not reach scarfree healing, which is fundamental for the facial skin, but rather scarless healing (look at Spievack's finger). Maybe you know more than I do and can make me more optimistic- I hope so.
If this is really going to happen its amazing. There will no longer be a need for this forum!!! I honestly can't believe it, feels so unreal that scarring, something which has affected humans forever will be eliminated. I mean a month away from release i can hardly contain myself.
Don't you think that this is a bit to early to be such enthusiastic? I'm also confident concerning the acell thing, but till now nobody has eliminated acne scars with it. I've read in one forum about complete elimination of stretch marks with acids+acell but another user has failed to erase his pitted acne scars with the same method. I think he failed, because he didn't remove the scar tissue completely, which is deeper than stretch marks. But how can you reach complete scar tissue erasing?
No serious doctor today would risk to cut out the scar and put acell on it in the hope that no new scar will develop. I think there is a lot of research to do in connection with acne scars+acell. Maybe someday it will be possible but don't think it will go such fast
Yea, I think expecting results for your scars in July is too soon, unless you are in a clinical trial for it with them, I think doctors will want to see some real results on scars before they cut too deep, like down to scar tissue and then apply acell. However, since people were getting their hands on the vet acell powder and doing their own peels at home and applying it, I foresee this happening first with the human grade acell, and then maybe we can see how many scars get erased. Even if the powder just produced more scar tissue to fill in the indent, kind of like TCA does over time, it would be nice. I think there is promise with it but I wouldn't want to try it first, as their may be a downside, who knows it is too new.
yea..dont get your hope up..dude...if it looks too good to be true it usually is...and what is the price tag...im so broke nowdays with the price of oil i probably couldnt afford it even if it was a miracle product.i hope it really des get rid of scrars..tomand you prove me wrong..but im not getting my hopes up on yet anything that doesnt work.
I can see how ECM could work to cure our scarring issues. It simply regenerates skin to the original state. However, the problem with our scarring is that it's not really an injury anymore. I noticed someone mention a step-by-step system of "wound then apply." I think someone mention doing a chemical peel then applying the powder. I just don't know if that's enough of an injury to fix it. I'm worried that the amount of wounding they need to do would have to be a pretty intense procedure. Maybe bringing back dermabrasion is a good option? I don't know, I'm just curious.
hoursafter-
the key to the scarless healing formula is that you need to eliminate all scar tissue first. For most all scars this means going much deeper than a chemical peel or a dermabrasion goes. All scars would likely need to be cut out, so the base of the scar is removed. So needless to say, this would be an invasive procedure, but every bit worth it if it could rid us of scars.
I just wanted to add that I called the number listed on the Acell website and spoke to someone who seemed to know what was going on. He confirmed that Acell will start distribution in July and that all you really need to do is find a doctor who is willing to order this and use it on you. So the next question is, how do we find someone who's willing to try this out for acne scars?
What kind of doctor would we be looking for? As I was discussing earlier, someone believed that the only way to get this stuff to work would be to cut out the scar deep. I know I've seen people on here who have cut out scars on areas of the body and left with just stitch scars. This seems to be the type of thing that acell could remedy. I'm just not sure about whether to contact plastic surgeons or dermatologists and if so what kind? Hmm...
I just wanted to add that I called the number listed on the Acell website and spoke to someone who seemed to know what was going on. He confirmed that Acell will start distribution in July and that all you really need to do is find a doctor who is willing to order this and use it on you. So the next question is, how do we find someone who's willing to try this out for acne scars?
What kind of doctor would we be looking for? As I was discussing earlier, someone believed that the only way to get this stuff to work would be to cut out the scar deep. I know I've seen people on here who have cut out scars on areas of the body and left with just stitch scars. This seems to be the type of thing that acell could remedy. I'm just not sure about whether to contact plastic surgeons or dermatologists and if so what kind? Hmm...
I guess if you wanted a spot dermabrasion you could go to Dr. Yarborough in New Orleans and request he use it on you, but he may say no. I think spot dermabrasion over one small scar would be the way to start with this. However, I wouldn't go to a doctor to get it done till I saw others results first, but others are more adventurous.
Firstly, don't get your hopes up too high for A-cell being our solution to scarring. No one has seen ANY proven scientific evidence that this agent works to prevent/reduce scarring in humans. Everything is anecdotal at the moment.
What I am surprised about is how A-cell is supposedly about to be released to the public in July?? Have no human clinical trials been required prior to release since this agent is for topical use only rather than intra-dermal? If this is true then A-cell will have made a massive dent into Renovo's potential Juvista profits as that is only scheduled to be released by 2009 at the earliest. Maybe this could spur Renovo on to be released even sooner but I doubt this would be feasible since it still has to pass Phase 3 trials and FDA approval.
Yes, for A-cell to work a surgeon will have to excise current scar tissue, stitch the wound back up and then apply the A-cell powder.
But it sounds all too good to be true: the early release date, possibility of tissue/digit regrowth, minimal downtime etc...but I will definitely keep my fingers crossed.
Firstly, don't get your hopes up too high for A-cell being our solution to scarring. No one has seen ANY proven scientific evidence that this agent works to prevent/reduce scarring in humans. Everything is anecdotal at the moment.
What I am surprised about is how A-cell is supposedly about to be released to the public in July?? Have no human clinical trials been required prior to release since this agent is for topical use only rather than intra-dermal? If this is true then A-cell will have made a massive dent into Renovo's potential Juvista profits as that is only scheduled to be released by 2009 at the earliest. Maybe this could spur Renovo on to be released even sooner but I doubt this would be feasible since it still has to pass Phase 3 trials and FDA approval.
Yes, for A-cell to work a surgeon will have to excise current scar tissue, stitch the wound back up and then apply the A-cell powder.
But it sounds all too good to be true: the early release date, possibility of tissue/digit regrowth, minimal downtime etc...but I will definitely keep my fingers crossed.
Yeah I know what u mean. Im keeping my fingers crossed too, but the results of acell application on animals are promising with full dermal thickness wounds being able to close. If you ask me to name a product that is as close to scarless healing as possible, i'll say acell.
Firstly, don't get your hopes up too high for A-cell being our solution to scarring. No one has seen ANY proven scientific evidence that this agent works to prevent/reduce scarring in humans. Everything is anecdotal at the moment.
What I am surprised about is how A-cell is supposedly about to be released to the public in July?? Have no human clinical trials been required prior to release since this agent is for topical use only rather than intra-dermal? If this is true then A-cell will have made a massive dent into Renovo's potential Juvista profits as that is only scheduled to be released by 2009 at the earliest. Maybe this could spur Renovo on to be released even sooner but I doubt this would be feasible since it still has to pass Phase 3 trials and FDA approval.
Yes, for A-cell to work a surgeon will have to excise current scar tissue, stitch the wound back up and then apply the A-cell powder.
But it sounds all too good to be true: the early release date, possibility of tissue/digit regrowth, minimal downtime etc...but I will definitely keep my fingers crossed.
It's not being released to the public, only to certified MDs. They have been doing trials with ECM for awhile, which is what acell is, just not in our scar context. If you read the acell website they state "A similar "first generation" ECM technology called SIS (derived from porcine small intestine) has been used to treat over 500,000 patients with remarkable effect." So I guess maybe this qualifies as trials?
One thing that seems wrong to me is the stitching back up of scars. It seems like the finger might have worked because the whole thing was in its natural state just minus the finger. I'm thinking you might just need to create an open wound on the skin, apply the powder, and then just cover it with some sort of seal or bandage or whatever. I could see stitching it up creating problems in the healing. I'm an economics major though, so what do I know about medicine, ha!
Has anyone seen this?
I'm guessing this is still pending confirmed results. This looks pretty interesting. Maybe its old news, i dunno. Found it today.
Has anyone seen this?
I'm guessing this is still pending confirmed results. This looks pretty interesting. Maybe its old news, i dunno. Found it today.
Ok link didnt work... Its at alizonne.co.uk/celltherapy
alizonne is the company and the article is under celltherapy
How is Acell significantly different than Oasis wound healing which has been available for quite a while.
Here is info on Oasis:
http://www.healthpoint.com/divisions/tm/prodOASIS.cfm#
I called Health Point and they said that Oasis is not used for scars at all.
How is Acell significantly different than Oasis wound healing which has been available for quite a while.
Here is info on Oasis:
http://www.healthpoint.com/divisions/tm/prodOASIS.cfm#
I called Health Point and they said that Oasis is not used for scars at all.
I've never researched oasis and I think someone might have posted about it on this thread I wouldn't be suprised, however I've read in a pdf file/or some file I have that other ECM materials have been artificially manipulated by man, were as Acell is much more pure and apparently man made adjustments at this stage in time do not beat the natural ECM that acell is. Meaning some of these man made adjustments get 95% regeneration, whereas Acell beats that.
Firstly, don't get your hopes up too high for A-cell being our solution to scarring. No one has seen ANY proven scientific evidence that this agent works to prevent/reduce scarring in humans. Everything is anecdotal at the moment.
Neca, from the way I see it, with the logical information I've seen and read I'm very excited. I've seen the regeneration on animals, were they would not follow the course, with 4X4 gaping wounds regenerated with fur, no scar here, just skin and fur. I've seen a finger regenerate on a man which got released in the press, it regenerated blood vessels, bone tissues much harder to regenerate than skin which is much easier; but more incredible than that is the late stage diabetic foot that I seen regenerated on TEDtalks.
When I first started to read up on the current technological advances in scar healing a few year ago, they used to say the chronological order of scar free healing would be: 1. on healthy people first, then 2. scar free healing on sick people second.
They used to say that you'd have scar free healing on the healthy and much later down the line you'd have it on the people with late stage diabetes getting scar free healing.
Well Acell messed this chronological order and blew it out of the water, those that be decided to demonstrate that it regenerated the skin on a late stage diabetic foot that hadn't healed for a year previous to the application of Acell; fuck regenerating a mere skin wound on a healthy patient as the demonstration.
The logical maths now say to me this = scar free healing for skin is almost here, if we could use the pure material what was used on that diabetic foot/ the animals with 4X4 wounds/the man who regenerated his finger skin and follow the course...
The Oasis (called: Oasis Wound Matrix) product is similar to the Acell ECM. That said, a small 3cm X 3.5cm sheet of Oasis costs approximately $160.
If purchased in a package the per-unit cost is reduced, but again quite expensive. I am not sure what the price of an Acell matrix would be, but should there be efficacy in the production process I imagine costs can be minimized. Due to increased competition between various manufacturers of xenogeneic extracellular matrix products, I imagine over the next few years the cost will be acceptable to most people.
BTW, Acell is simply marketing a xenogeneic ECM, which doesn't just include Oasis as direct competition. There are many companies working in this field. There is one factor that I do not know since I have not worked with ECMs in the past. That would be whether there is a difference in imbedded cellular signals between the UBS and SIS derived ECMs. I doubt there would be a great difference, since both these tissues are very capable of rapid and nearly perfect regeneration within a healthy organism. The small intestine's tissue for example can heal itself from ulcers without much if any signs of scarring, just like the oral mucosa. These tissues are actually quite similar on a histological level.
Either way, I have colleagues that work with Oasis and apply it to diabetic ulcers, burn wounds and even road rash victims among other things. I do not know of anyone who has tried it on acne scars. However, after reading up on Acell over the last week I have come to the realization that there really aren't significant differences between its ECM and the Oasis ECM. Read up on xenogeneic ECMs and you'll understand the similarity.
I also want to caution people about the digit regrowth. There was no digit regrowth per se. The man's finger was cut above the third joint beyond the base of his nail. There was tissue regeneration, but not bone regeneration. That's a known fact in the medical community. That said xenogeneic ECMs do carry plenty of beneficial cellular signals and they have been shown to allow tissue differentiation that includes various layers of muscle, fat and skin. In some cases, there have even been small bone growths, but not on an advanced level that could result in complete limb (joints, tendons, muscles, bones, etc...) growth. Perhaps with a specialized scaffold this may however be accomplished.
I asked my colleague, Dr. Antonov, who works with burn victims where he purchases xenogeneic ECMs. He buys directly from the manufacturers but he did explain to me that they are also found on the internet. I did a quick search and indeed Oasis ECMs can be purchased by anyone from internet stores. I also found photos showing the regeneration capabilities of their product. Interestingly, these photos are very similar to the ones shown by Acell.
If anyone wanted to try such a product on a small excised acne scar, then they would not have to wait for an Acell ECM to be released for human use. Results should be similar if not identical with another xenogeneic ECM. I am actually thinking of trying this in conjunction with an artificial blastema, but as I say I have no experience with these products and I will have to be very careful not to create a bigger scar by attempting this theoretically beneficial yet practically untested acne scar revision procedure.
Anyway, thanks to all of you on Acne.org, this may actually turn into something useful for people the world over. Your collective goal in the form of a unified vision for scarless healing, has the power of unlimited creativity through the sharing of ideas, theories and practical experience... All your minds put together are more capable of coming up with an effective treatment for acne scars than anyone doctor. That's also a fact!
Well one thing I noticed is that ACell is manufacturing a powder where as Oasis only makes the matrix bandage type application thingy. I'm not sure if that makes much of a difference, but I could see a powder being more able to be thoroughly applied.
What kind of results are seen on the burn or road rash victims?
Finally there's still a now what? feeling. How can we try this stuff? Even if I can buy it already online, where would I possibly start? I can't excise a scar from myself and it'd be hard to talk a doctor into trying a "practically untested" procedure. I just want to jump right in.