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[Sticky] Scarless Healing

 
MemberMember
14
(@bloodwar44)

Posted : 10/23/2014 12:31 pm

http://m.phys.org/news/2014-09-nanofibrous-hydrogels-wounds-regeneration-skin.html

 

Newest hydrogel news, it appears hydrogel improve scar by 30%

please stop spreading lies... not all hydrogels are equal...and even if they are....where is any mention of 30%?

 

Did shahul kahul tell you that?

 

Hey, everybody. I found something. I am very surprised there is so little information about it. Study from last year:

http://www.ncbi.nlm.nih.gov/pubmed/24317052

It's about the effect of resveratrol on scars. http://en.wikipedia.org/wiki/Resveratrol

As I understand the text, 80% reduction of existing scars in 3 days (72 hours), with a substance (resveratrol) that is out there to buy now. So not about new wounds, but scars already formed. Used with DMSO and growth medium. This was not tried in mice but on an excised human scar. 80% reduction of the types of collagen that forms the scar.

Concluding statement: "resveratrol is a potential agent for HS treatment."

So a very good thing if this works out: resveratrol is already approved and you can get it without prescription. So it's not sitting in a lab somewhere unavailable to the public like the hydrogel. It's also kind of cheap.

I do not know if resveratrol comes in different types, as a supplement it comes as a powder.

Chinese researchers, I suppose it's hard to contact them.

It would be good if someone with more technical understanding than me could read through the paper and see what conclusions should be drawn from it.

This seems to be about hypertrophic scarring though.

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MemberMember
5
(@ser25)

Posted : 10/23/2014 2:25 pm

For acne, there was a study using resveratrol for 30 days which got a 54% improvement.

http://m.wisegeek.com/how-effective-is-resveratrol-for-acne.htm

http://www.cbsnews.com/news/can-you-get-resveratrols-anti-aging-benefits-by-putting-it-on-your-skin/

 

But anyway, even if the study I linked to in my earlier post above only applies to hypertrophic scars: there are millions of people out there with such scars and this is perhaps a simple solution to a huge unmet need, then why on earth isn't someone picking up on this? What's going on here? I don't mean this forum specifically but the world and the medical research community. The study was published over ten months ago.

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MemberMember
14
(@bloodwar44)

Posted : 10/24/2014 1:25 am

For acne, there was a study using resveratrol for 30 days which got a 54% improvement.

http://m.wisegeek.com/how-effective-is-resveratrol-for-acne.htm

http://www.cbsnews.com/news/can-you-get-resveratrols-anti-aging-benefits-by-putting-it-on-your-skin/

 

But anyway, even if the study I linked to in my earlier post above only applies to hypertrophic scars: there are millions of people out there with such scars and this is perhaps a simple solution to a huge unmet need, then why on earth isn't someone picking up on this? What's going on here? I don't mean this forum specifically but the world and the medical research community. The study was published over ten months ago.

Because you can get 54% elsewhere easily

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MemberMember
7
(@scarsgone2017)

Posted : 10/24/2014 3:54 am

@bloodwar44 : no, with current treatments you can hardly get even 10%, while hydrogel could get 30%++

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MemberMember
5
(@ser25)

Posted : 10/24/2014 5:55 am

For hypertrophic scars there was a 60% reduction after 24 hours, a 70% reduction after 48 hours and an 80% reduction after 72 hours of treatment (it's in the paper) and as far as I know there is nothing out there that even slightly reduces hypertrophic scars. I'm still bullish on this.

 

As I understand the paper: resveratrol actually kills off the cells in the collagen deposits, and collagen deposits=scar. So not some "smoothing" or "flattening" but actual eradication of the scar tissue.

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MemberMember
14
(@bloodwar44)

Posted : 10/25/2014 11:18 am

All i find in the articles is the reduction of acne (and not scars) by 54%

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MemberMember
5
(@ser25)

Posted : 10/25/2014 2:47 pm

All i find in the articles is the reduction of acne (and not scars) by 54%

Bloodwar, I mean this link:

http://www.ncbi.nlm.nih.gov/pubmed/24317052

And here is the full text:

https://www.jstage.jst.go.jp/article/bbb/77/12/77_130502/_pdf

 

 

And you can all see that it says "treatment" for scars.

"Treatment", not "prevention".

You wouldn't even have to bother removing the scars by surgery to create a new wound. Just treat them as they are.

Maybe this has got no attention because there is no money to be made for a pharmaceutical company since resveratrol is already for sale, so they can't make a new product with a high price.

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MemberMember
14
(@bloodwar44)

Posted : 10/25/2014 3:08 pm

 

All i find in the articles is the reduction of acne (and not scars) by 54%

Bloodwar, I mean this link:

http://www.ncbi.nlm.nih.gov/pubmed/24317052

And here is the full text:

https://www.jstage.jst.go.jp/article/bbb/77/12/77_130502/_pdf

 

 

And you can all see that it says "treatment" for scars.

"Treatment", not "prevention".

You wouldn't even have to bother removing the scars by surgery to create a new wound. Just treat them as they are.

Maybe this has got no attention because there is no money to be made for a pharmaceutical company since resveratrol is already for sale, so they can't make a new product with a high price.

you should try buying some, there appears to be some gels with reservatrol out there.

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MemberMember
21
(@repola)
MemberMember
9
(@imad)
MemberMember
14
(@bloodwar44)

Posted : 10/25/2014 11:56 pm

that is one of the research goiing on about scar free healing, unfortunately, it will probably take more than 10 years.

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MemberMember
9
(@imad)

Posted : 10/26/2014 5:48 am

so slack i dont want to be 30, just hope i can get theses semi decent with what treatments we have left, what helps me most is that in 100 years time noone will even remember us, or care what we did and people gota die one day may as well go with a bit for damage i suppose.

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MemberMember
19
(@sndr)

Posted : 10/26/2014 6:19 am

I've wasted enough time with these mother f***ing scars, come out with something already! Literally, life is passing us by.

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MemberMember
5
(@ser25)

Posted : 10/26/2014 7:07 am

I've wasted enough time with these mother f***ing scars, come out with something already! Literally, life is passing us by.

What type of scars do you have SNDR? Resveratrol as I talked about earlier might be worth a try because it might just work.

 

And also, how old are you? If you are fairly young then you have a big chance of being able to live forever because there are researchers today who believe aging will be defeated in as little as 20-25 years by rejuvenating the human body.

 

So try resveratrol now. If it doesn't work, wait for the hydrogel which will likely be out in 3-4 years. And then look forward to have your body rejuvenated and living for thousands of years without scars.

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MemberMember
19
(@sndr)

Posted : 10/26/2014 7:25 am

@ser25

I'm 25. *sigh*

Resveratrol is a natural testosterone producing, estrogen inhibitor, or am I mistaken?
You can get it from things like peanuts and grapes, no?
How does it work for acne scars? :S

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MemberMember
5
(@ser25)

Posted : 10/26/2014 7:53 am

See my links on page 277 of this thread.

 

But it's important to understand, that if you are 25 then you will likely live for at least another 50 years naturally and there is a very high likelihood that aging will be defeated during those 50 years, certainly greater than 50% probability, maybe around 70-80%, which will allow you to then go on living forever.

 

Everyone has the intuituon that you are only young once, but this might not be true for our generation.

 

But about resveratrol, the study that says it can treat scars, that was about hypertrophic scars and not acne scars. But who knows it might have an effect on acne as well but I don't know.

 

But you can buy it pure in much higher concentrations than in the foodstuff you mentioned.

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MemberMember
9
(@imad)

Posted : 10/26/2014 8:16 am

The will cause all kinds of oveerpopulation problems, better start investing in land yo me thinks

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MemberMember
14
(@bloodwar44)

Posted : 10/26/2014 9:22 am

living forever kind of sucks lol

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MemberMember
7
(@scarsgone2017)

Posted : 10/26/2014 10:27 am

Better than scarring forever i guess

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MemberMember
19
(@sndr)

Posted : 10/26/2014 10:31 am

Interesting, I'll do more research on resveratrol.
Honestly, I rather just live my young years happily, without scarring, than live forever.
Acne scarring destroyed years of my life and I want them back!

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MemberMember
7
(@scarsgone2017)

Posted : 10/26/2014 12:04 pm

Interesting, I'll do more research on resveratrol.

Honestly, I rather just live my young years happily, without scarring, than live forever.

Acne scarring destroyed years of my life and I want them back!

 

Dont be weak, only scar

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MemberMember
6
(@jt1986)

Posted : 10/26/2014 8:26 pm

Regarding that, different, hydrogel... I don't see the 30% quoted anywhere in the abstract.

 

Worse yet is that they apparently only ran the trial for two weeks, when signs of further regeneration were still being observed (in their own words, see the hair note), which means that we have no real idea of what the final result could be.

 

See the scientific paper related to the study here: http://www.sciencedirect.com/science/article/pii/S0142961214002038?via=ihub

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MemberMember
19
(@sndr)

Posted : 10/26/2014 9:18 pm

@scarsgone2017

That makes no sense maricon.

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MemberMember
9
(@imad)

Posted : 10/26/2014 9:28 pm

edit

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MemberMember
73
(@seabs135)

Posted : 10/26/2014 10:45 pm

JT1986, I also nearly posted on this one because of the fact he did not really label what he was talking about, he just made some oblique remark... But I come to the decision if I talked to him on this it would give him his response. IMO he is deliberately posting misleading information to get a rise... Beyond this, two times he has posted links to people who you cannot trace... Also more subtly, he is also apparently not bothered by his scarring, yet he posts concern on a message board about scarring...

Regarding that, different, hydrogel... I don't see the 30% quoted anywhere in the abstract.

Worse yet is that they apparently only ran the trial for two weeks, when signs of further regeneration were still being observed (in their own words, see the hair note), which means that we have no real idea of what the final result could be.

See the scientific paper related to the study here: http://www.sciencedirect.com/science/article/pii/S0142961214002038?via=ihub

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