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[Sticky] Scarless Healing

 
MemberMember
73
(@seabs135)

Posted : 10/18/2014 8:25 pm

 

I listened to the interview, it said nothing about hydrogel... How do we know if they're talking about something else, JHU does like over 200 different labs each year, how do we know this is hydrogel specific, if I'm mistaken, please refer me to the timestamp at which the speaker spoke about the hydrogel research. Thanks.

Justaboy, I assume you are maybe talking to JT1986, and/or me, and/or Repola? If you are not referring to me ignore this post.

Ill assume you are talking to me, and with respect Ill answer you. So what is the pod cast mainly about? It is primarily a discussion with an entrepreneur about investing in a specific region in the US, nothing out of tune with the other website interviews, which you can see... On to the gel, the gel is referenced and indirectly referred to many times; beginning with the lead. The lead which is the synopsis to the pod cast. This lead, by mentioning the company which is developing the gel, guides us that a segment of the pod cast will be going over or at the least referencing that product, and then building an interview or part of an interview from that productin some way, at least secondarily.... You can read the lead from the web page: http://earlyinvesting.com/episodes/episode-7-george-davis/

Back to the references, with regards to the lead again; in the lead, it mentions Gemstone which has one product... This reference answers your hydrogel query immediately... In fact the gel cannot fail to be referenced because of that verified instance in the lead. So straight away you can see the gel is referenced just by reading the lead which references gemstone Going on and all that being said, in the pod cast, prior to the interview the host Peter Clough introduces the interview, by talking about the fact that 'Gemsone' is working on a treatment that is currently being tested on animals... This is another reference and so on, btw, it also gives the current state... And with regards to JT1986 if you listen from 15 minutes, youll see what he has said, is referenced fairly, so if you are opinionating to him, he is also referenced.

Thanks for your reply! How long do you think the ETA for hydrogel would be? IMO, I think maybe one or two years, and it will be popularized the year after, making it as affordable as buying mederma. Btw, why does hydrogels interest you if I may ask? For me, I want good skin, and for everyone to be "cured" of acne scars, and the "emotional pain" caused by it.

I would love for something like this to be out asap, I keep imagining that a word of mouth or some passed on public knowledge would get something out faster or push things along... I'm probably seriously naive in that respect. And not many get my way of thinking. Regarding your prediction, I reckon you'll be roughly right in your prediction, as your predictions are similar to what has been stated in various sources if it goes through the trial process. BTW, the hydrogel interests me as it got regeneration of a full thickness wound, as I have scarring I found it interesting, but I'm fair weathered, I'm interested in anything that has that type of qualification in the science.

.

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MemberMember
7
(@scarsgone2017)

Posted : 10/19/2014 7:14 pm

Under a different account maldixion?

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MemberMember
7
(@scarsgone2017)

Posted : 10/20/2014 12:31 am

Seabs i got a question for you, sorry i cant state the source but i recall somewhere on the internet that once we are scarred, it overwrite our DNA into scarring state. Is this true?

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MemberMember
7
(@scarsgone2017)

Posted : 10/20/2014 12:49 am

http://curezone.com/forums/am.asp?i=837982

 

Here is the article....

Hope its another scam

 

Thats what somehow contradictory of what jt1986 stated earlier that our body will not forget what its programmed to do..

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MemberMember
29
(@cycloverid)

Posted : 10/20/2014 9:44 am

Another stem cell article (two links for the same finding), sounds promising but likely sensationalized:

http://en.rocketnews24.com/2014/10/20/has-a-japanese-company-found-the-fountain-of-youth-one-mans-youthful-skin-suggests-so/

http://ajw.asahi.com/article/business/AJ201410160032

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MemberMember
2
(@justaboy)

Posted : 10/20/2014 6:36 pm

Sounds so much more promising than hydrogel... But still in basic research... Whatever that means! XD I don't think there may be a cure within the next year or two, but we can hope. Lol.

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MemberMember
21
(@repola)

Posted : 10/20/2014 7:45 pm

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.

Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration.

 

http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

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MemberMember
2
(@justaboy)

Posted : 10/20/2014 8:55 pm

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

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MemberMember
73
(@seabs135)

Posted : 10/20/2014 9:44 pm

scarsbegone that information is from curezone, not the National Academy of Sciences...

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MemberMember
29
(@cycloverid)

Posted : 10/21/2014 7:04 am

 

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

Earlier this year they were talking about starting human trials possibly by the end of the year. That is definitely too early given that we've heard nothing from them since they reported about it earlier this year.

 

They also said that the pig tests should finish by the summer. That could have happened (given the care needed to properly peer review the findings), but it's radio silence about that too.

Nobody knows anything for certain atm. It could be that they are being really careful and being quiet, or some complication emerged, or that it doesn't work -- but they seemed optimistic last time they spoke about it.

I'd say if we're lucky, 2-5 years from now, if at all.

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MemberMember
7
(@scarsgone2017)

Posted : 10/21/2014 7:10 am

Dont worry its within 20 years mark

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MemberMember
29
(@cycloverid)

Posted : 10/21/2014 10:11 am

Dont worry its within 20 years mark

Something big will come in less than 10 years with the way things are (exponentially) advancing. We live in exciting times.

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MemberMember
14
(@bloodwar44)

Posted : 10/21/2014 2:32 pm

Not as exciting as it would have been if we had scars 10 years later.

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MemberMember
73
(@seabs135)

Posted : 10/21/2014 4:12 pm

Justaboy, at the end of the day, a methodology inside a dated document, signed by many scientists and published in the National Acedemy of the Sciences, got complete regeneration of a 3rd degree burn.

 

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

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MemberMember
6
(@jt1986)

Posted : 10/21/2014 11:10 pm

http://curezone.com/forums/am.asp?i=837982

Here is the article....

Hope its another scamThats what somehow contradictory of what jt1986 stated earlier that our body will not forget what its programmed to do..

For the record, I reaffirm that the body never forgets what it is programmed to do. If you cut out the scar tissue, the body will re-start the healing process. And that is exactly what you asked, not why scarring occurs in the first place. Hence my answer in post #5392: "The body does not "forget" what is is programmed to do, remove the damaged tissue and the healing process will begin once again. The DEX-AE is applied directly to the wound bed after the tissue is removed."

 

And not only that, but I believe that the reason why scarring occurs and how the DEX-AE interacts with it was already explained in FaceBook. If that explanation wasn't directed towards you (I have a few people sending me PMs in FB), my apologies, but please don't assume that I'm unaware of the basics of my profession.

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MemberMember
14
(@bloodwar44)

Posted : 10/22/2014 8:52 am

 

Justaboy, at the end of the day, a methodology inside a dated document, signed by many scientists and published in the National Acedemy of the Sciences, got complete regeneration of a 3rd degree burn.

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

you keep quoting this as your hope but do note that even if it did work on mice. Its still almost a 50-50 chance if it will work in humans.

IF hydrogels pass pig testing which is long overdue, it still may not work on humans. If it works on humans, it still may not provide scar free healing, maybe only reduced scarring. If it really produces scar free healing, if it costs $10000 a spot, just like stem cell fat grafting, you still wont be able to get it.

 

For a guy with third degree burns like me , tbh it doesnt seem very hopeful. I would need full freaking body hydrogel wrap .

 

 

Dont worry its within 20 years mark

Something big will come in less than 10 years with the way things are (exponentially) advancing. We live in exciting times.

That is what they thought 10 years ago. They thought we would be riding in flying cars too.

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MemberMember
7
(@scarsgone2017)

Posted : 10/22/2014 9:19 am

@bloodswar : you are lucky even though you get 3rd degree burn, you dont get it on face... imagine people who have scars on their faces please...

 

 

Be pitiful to them

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MemberMember
29
(@cycloverid)

Posted : 10/22/2014 10:53 am

 

Justaboy, at the end of the day, a methodology inside a dated document, signed by many scientists and published in the National Acedemy of the Sciences, got complete regeneration of a 3rd degree burn.

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

you keep quoting this as your hope but do note that even if it did work on mice. Its still almost a 50-50 chance if it will work in humans.

IF hydrogels pass pig testing which is long overdue, it still may not work on humans. If it works on humans, it still may not provide scar free healing, maybe only reduced scarring. If it really produces scar free healing, if it costs $10000 a spot, just like stem cell fat grafting, you still wont be able to get it.

 

For a guy with third degree burns like me , tbh it doesnt seem very hopeful. I would need full freaking body hydrogel wrap .

 

>

Dont worry its within 20 years mark

Something big will come in less than 10 years with the way things are (exponentially) advancing. We live in exciting times.

That is what they thought 10 years ago. They thought we would be riding in flying cars too.

Flying cars will be a reality soon:

 

But I don't wish to argue with you. I realize that things will never move fast enough for those in need, but we are lucky that we have the chance to get a cure for this in our lifetimes. 50+ years ago and you'd be stuck without hope.

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MemberMember
14
(@bloodwar44)

Posted : 10/22/2014 12:34 pm

@bloodswar : you are lucky even though you get 3rd degree burn, you dont get it on face... imagine people who have scars on their faces please...

 

 

Be pitiful to them

Its all over my face and body, much much worse than any of your "acne scars" that only show up in the sunlight, i was saying that even if they could fix my face, i would need a full body wrap of hydrogel to get back to normal and they would literally have to slice off skin from my entire body and remove full thickness tissue. Pretty much like skinning someone alive.

 

 

 

 

 

 

 

Justaboy, at the end of the day, a methodology inside a dated document, signed by many scientists and published in the National Acedemy of the Sciences, got complete regeneration of a 3rd degree burn.

Scars are not skin, you can get scars in almost any part of the body, liver, lungs, skin etc. If the damage is deep enough the organ can not regenerate and the body creates a scar. Dextran hydrogel is a scaffolding that helps the body to create new skin instead of scar tissue.Actually is a kind of ECM that mimics the embryonic skin niche for intact skin regeneration. http://www.jscimedcentral.com/Regenerative/Articles/regenerative-2-1007.php

What is your ETA for hydrogel? Do you think that it will come soon? Angiogenic healing sounds crazy, and how can hydrogel facilitate the growth of specialized skin cells onto one area?

you keep quoting this as your hope but do note that even if it did work on mice. Its still almost a 50-50 chance if it will work in humans.

IF hydrogels pass pig testing which is long overdue, it still may not work on humans. If it works on humans, it still may not provide scar free healing, maybe only reduced scarring. If it really produces scar free healing, if it costs $10000 a spot, just like stem cell fat grafting, you still wont be able to get it.

 

For a guy with third degree burns like me , tbh it doesnt seem very hopeful. I would need full freaking body hydrogel wrap .

 

>>>>>>

Dont worry its within 20 years mark

Something big will come in less than 10 years with the way things are (exponentially) advancing. We live in exciting times.

That is what they thought 10 years ago. They thought we would be riding in flying cars too.

Flying cars will be a reality soon:

 

But I don't wish to argue with you. I realize that things will never move fast enough for those in need, but we are lucky that we have the chance to get a cure for this in our lifetimes. 50+ years ago and you'd be stuck without hope.

 

I meant flying cars that are available to mainstream people and being used by the world and on every street, not millionaires who can afford to buy yachts and take space shuttles around the world for fun. its unlikely that you, personally, will be in a flying car even 10 years from now , flying to work.

 

Scar free healing in a way is the same. We are saying that soon we can overcome the body's natural mechanism of scarring that has been happening for tens of thousands of years. Which is a pretty big thing considering we can't even cure the flu right now .

 

 

anyway I am only mentioning this because someone on the facebook page asked gemstone "why they have to price it right to compete". Obviously severe burns from accidents dont happen like small pimple spots and you will need a lot more treatment for it.

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MemberMember
73
(@seabs135)

Posted : 10/22/2014 4:19 pm

Bloodwar44, this is something that got degraded rapidly and got complete regeneration of a third degree burn, the control did not, and this is in a reliable historical scientific document. (I'm going on, again, but restating a fact...) Now we have evidence, this is not a big thing to imagine, it degraded and got complete regeneration...

Edited: As I sound like a misery...

Bloodwar another thing you say is I'm going on about something, like if I'm debating something on an internet messageboard? or as if I'm debating some concoction on a message board? All Im doing is keeping to the framework of the facts using few words as possible... Im deliberately debating nothing here... To me a debate would be a faux debate, kind of like debating a football score. Imo a perceived debate here, debases the evidence. Sometimes it can even be pointless posting these facts on an internet messageboard, as I think some people actually do sometimes believe this evidence is up for debate, and therefore it is up to be prejudiced and obscured by baseless opinions and assertions...

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MemberMember
7
(@scarsgone2017)

Posted : 10/23/2014 12:35 am

I like seabs optimism and thats really comforting...

 

He really turns abiguity between hope and despair into more to the hope side...

 

I like u man...hope this hydrogel works..

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MemberMember
73
(@seabs135)

Posted : 10/23/2014 7:10 am

Scarsgone I'm guessing you mean well but what I've stated is not an optimistic or a pessimistic assertion... What I've stated is a standard that has been shown in a scientific document.

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MemberMember
9
(@imad)

Posted : 10/23/2014 7:40 am

http://www.ioffer.com/i/beyond-plus-acnesil-silicone-scar-gel-10g-570412773

This claims to do something but i'll let u guys deceide looks like it hasn't been out of long imo

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MemberMember
7
(@scarsgone2017)

Posted : 10/23/2014 9:24 am

http://m.phys.org/news/2014-09-nanofibrous-hydrogels-wounds-regeneration-skin.html

 

Newest hydrogel news, it appears hydrogel improve scar by 30%

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MemberMember
5
(@ser25)

Posted : 10/23/2014 11:14 am

Hey, everybody. I found something. I am very surprised there is so little information about it. Study from last year:

http://www.ncbi.nlm.nih.gov/pubmed/24317052

It's about the effect of resveratrol on scars. http://en.wikipedia.org/wiki/Resveratrol

As I understand the text, 80% reduction of existing scars in 3 days (72 hours), with a substance (resveratrol) that is out there to buy now. So not about new wounds, but scars already formed. Used with DMSO and growth medium. This was not tried in mice but on an excised human scar. 80% reduction of the types of collagen that forms the scar.

Concluding statement: "resveratrol is a potential agent for HS treatment."

So a very good thing if this works out: resveratrol is already approved and you can get it without prescription. So it's not sitting in a lab somewhere unavailable to the public like the hydrogel. It's also kind of cheap.

I do not know if resveratrol comes in different types, as a supplement it comes as a powder.

Chinese researchers, I suppose it's hard to contact them.

It would be good if someone with more technical understanding than me could read through the paper and see what conclusions should be drawn from it.

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