Sounds legit

Is this the same person that was quoted saying that he had "inside info"? He can barely communicate coherently, I can't believe that someone took his trolling seriously.

PD- For anyone interested, the Lab is back at it and has several papers pending review, one of them is titled "The design of dextran-based hypoxia-inducible hydrogels via in situ oxygen consuming reaction". It seems parallel to the DEX/AE.

Those concerned with the "funding" should learn more about Davis' partner at Gamma 3, Dave Oros. Begin by searching for the success that Aether Systems (a bit of a throwback to the 90s) had under his original model.

just a confirmation, are we talking about scar free healing or scarless healing.

Sun doesn't make it very clear if he's talking about functional recovery of skin or complete regeneration of cosmetically decent skin

Also, is this only for burns?

Bloodwar44, the paper states the 'Dextran Hydrogel results in complete regeneration.' It was tested/scienced on full thickness wounds and 3rd degree burns, the worst kind of skin damage you can get.

But my question is :

1.how if we are already scarred beforehand

2. Does the body still remember what our skin used to like before the scarring occur?

3. How long will it take for skin to fully heal after the excision and dextran hydrogel applied?

yeah , whether it works for existing scars, i'm a little worried.

Is this the same person that was quoted saying that he had "inside info"? He can barely communicate coherently, I can't believe that someone took his trolling seriously.

 

PD- For anyone interested, the Lab is back at it and has several papers pending review, one of them is titled "The design of dextran-based hypoxia-inducible hydrogels via in situ oxygen consuming reaction". It seems parallel to the DEX/AE.

 

Those concerned with the "funding" should learn more about Davis' partner at Gamma 3, Dave Oros. Begin by searching for the success that Aether Systems (a bit of a throwback to the 90s) had under his original model.

Does this mean that the hydrogel is successful in it's trials? Where can I find more info on this? I can't find much news on this or specifics. I really hope this goes well.

It has been stated but i forgot where that even if the method is to be found in the future, it is not a cure, its rather a prevention.. those who are already scarred could say goodbye to their original skin...

yes scarsgone you should say goodbye to your original skin

Slow down , geez, no need to get so emotional.. im sorry, im just drawing conclusion of the first sentence of my last post

It has been stated but i forgot where that even if the method is to be found in the future, it is not a cure, its rather a prevention.. those who are already scarred could say goodbye to their original skin...

I don't understand why it's a prevention rather than a cure. Didn't the hydrogel state that it can heal scars such as third degree burns? How would that work?

The Harmon lab has spawned a biotechnology startup Canton Biotechnologies Inc. Canton is currently embedded in Johns Hopkins University. Its mission is to commercialize wound healing strategies being discovered in the Harmon Lab.

This is how it works, when you are burned, quickly apply the hydrogel before the scarring occurs.. if the scar already formed, then just sing a goodbye song i guess

The only ones that really know how well the trials went are the members of Gerecht Lab and Gemstone/Gamma 3. No "massive leak" has happened, only bits of information are released irregularly. However, if you go back a few pages you will notice that there are a few hints that the gel is at least functional enough to warrant the hiring of professionals at Gemstone. That company's portfolio is composed exclusively by the Gerecht patents and they call the DEX-AE their "foundation technology".

The body does not "forget" what is is programmed to do, remove the damaged tissue and the healing process will begin once again. The DEX-AE is applied directly to the wound bed after the tissue is removed. It's functionality depends exclusively on "enhancing" (perhaps "accelerating" would be a best word) the body's capacity to heal itself and that process only occurs when there is an open wound. In the case of pre-existing scars, those would need to be excised and the gel would be applied to the wound bed. If you read the paper you will get a better picture of the MO employed.

Canton has been active for a couple of years, but despite Dr. Harmon's collaboration in the initial study, Gemstone is pretty much the one in charge now.

scarsgone, you think this some pimple cream or something man?

Anyway the hydrogel was applied only after the burned skin was excised.

And if you think that the scars can't be helped by the hydrogel then why in the world are you asking about it?

Just saying , do you know how many people on this forum are waiting for that one thing to help them get by from their scars?

Do you think you should tell spread false information to "say goodbye" to their unscarred skin? What if someone commits suicide? I know many people who have this as their last hope.

Please verify your facts before you post things like that.

Gemstone is more or less the Gerecht commertial company and Carton is the Harmon one but seems Gemstone has the rights about the hydrogel.

but it does seem strange. This seems like the most likely product to go scar free, yet there is very little support for it..... why?

Just to clear some things up, the original paper's hydrogel was used on mice after they suffered 3rd degree burns and had the wound area excised. This would be the same process used in old scars; you would cut out the damaged area, thus creating a wound bed, and the hydrogel would be placed over the wound bed to facilitate scar free healing (e.g. with appendages, sebaceous and sweat glands etc.).

You couldn't just put the hydrogel on an existing scar and have it change the morphology of the damaged skin back to healthy skin; you would need to have the damaged skin cut out.

It terms of why it hasn't gotten more support, I'd imagine it has something to do with so much research being done in this field with so many methods to achieve the scar free healing end. Yes, the hydrogel is the most promising because of its results AND because it's a device and wouldn't face the same regulatory hurdles. But there are loads of other options for investors to choose from when it comes to what they think will have the biggest payoff (e.g. stem cells, regulating gene expression and so on).

And it's not like Gerecht and her lab haven't received a good bit of support. Gemstone is behind them and they were renewed for their NHLBI (National Heart, Lung, and Blood Institute). I think the support is there, these things just take time; more time than we want it to take anyway.

Thank you all for the information! So nice to see people discuss this thread. I just wish this had more publicity so that people know that there is research being done for their 3rd degree scars, pregnancy scars, acne scars, or really any type of scars. I'm think I'm going to spread this to certain people and hopefully it will be noticed. Just hoping though

Gemstone is more or less the Gerecht commertial company and Carton is the Harmon one but seems Gemstone has the rights about the hydrogel.

Yeah. The deal was completed in Dec. 2013 and Gemstone has been in charge ever since.

@bloodwar44 : yeah i know, i feel you man.. like all other members in this board. And believe me i am suffering like all of you mentally.

Not a single day i am not haunted by my own thoughts about suicide.. feeling i dont deserved to live this living hell..

1. i cant go out for lunch with my friends fearing the sun might reveal my monstrous face

2. I cant talk to anyone without looking away from them

3. My performance dropped drastically due to my goal is not about work but about going home and hiding

4. I lament myself without knowing what ive done wrong to ruin my face like this

5. My original goal is replaced by a goal to find a cure

6. Every road every scene every music i hear i come across twist my mind reminding me how happy i was when i used to have healthy skin

All those torments me , so once again i tell you i know how you all feel..but sometimes i just cant help myself when i am in despair thinking there might be no cure at all

Well for me i was a handsome actor, then I got into a horrible car accident which left my face and body disfigured and pretty much lost my entire career and social life

Im so sorry to hear that... saying like your skin will forever be that way must be tough...i too still have faith that a total cure for scarring be in our lifetime... no more like before my 30 hopefully

if hydrogel works then yes, but if it fails in human trials then there might be no hope

Hi bloodwar44, I have suffer a stupid accident, I have got scars in my face, I have no social live, I can`t sleep,I can`t eat, and I almost lose my job a few times, I have tryed with non ablative lasers without any improvement.

I will try ablative lasers or dermoabrasion but I don`t spect any miracle. the hydrogel is a good candidate for

for scar free healing but the large animals results are taking too much time and only the Gerecht team knows something.

Meanwhile I can tell you that you are not alone, we are in the same vessel.