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Don't be so gullible. Directly contacting the team has been extremely difficult for those of us that have actually tried to do so by using our names, never-mind "someone in a forum". Furthermore, if it was unlikely that such information would be leaked before, now that the viability of the product depends on third party funding it is going to be nearly impossible. This is business, and protecting the IP is a key for success.
He is either quoting a troll, or is a troll himself.
Well, it's research being performed at JHU, but not by Gerecht's team. Zhaoli Sun is not the same Sun that worked on the original Hydrogel paper (Guoming Sun) in case anyone is wondering.
Really, this is just another approach their team is taking toward the same end. And since both products being combined are already on the market, in all likelihood this could be commercialized even quicker than the dextran hydrogel.
It's good news since every little bit of research into wound healing is great, but it's not related in any way to the work Gerecht is doing with the hydrogel; at least as far as I can tell (and doesn't provide the same results, even in mice). For example, Gerecht's lab website does not have this publication listed and she works at the Engineering School at JHU whereas Zhaoli Sun works at the School of Medicine.
Great find anyhow!
Here is another recent wound healing article:
This one is interesting because it allegedly treats the following (listed in the link):
- burn wounds,
- split-thickness skin graft donor site wounds,
- aesthetic treatment wounds (caused e.g. by dermabrasia ablative laser, deep chemical peel),
- radiation wounds,
- skin lesions caused by toxic epidermal necrolysis and
- skin lesions caused by genetic diseases such as epidermolysis bullosa.
So it looks like they're maybe aiming for post-laser, post-dermabrasion application which is somewhat exciting.
This article is also interesting if you're into general regenerative medicine:
They even managed to create livers and kidneys out of stem cell....is it that hard to just cut scar tissue out, and throw some stem cells to fill the gap? Dammit
Well, thus far I think they've only managed to print small scale livers and kidneys and obviously not ones that are ready to be transplanted into someone. And according to Wake Forest University (the leaders in 3D Bioprinting of organs) their end goal is actually to improve function and replace damaged tissues, not necessarily to do full transplants. Here's an article about it on their site:
http://www.wakehealth.edu/Research/WFIRM/Research/Engineering-A-Kidney.htm
And in terms of wound healing, from everything I've read it's one of the most complicated things that takes place in the human body, with so many growth factors and cells working together to form a scar that it's a daunting task to know which things to deactivate or alter in order to get scar free healing. Plus, with stem cells there are safety risks. Luckily, with the hydrogel in the paper they weren't using stem cells (even though that was their initial long term goal and is still something they're exploring).
But yes, I wish it would happen faster.
Those links have nothing to do with the hydrogel, the knowledge base on the gel is already known, as has been cited. But still it looks like a good scientific study. Someone probably noted when organs are rejected by the body, the body produces a scarring response to eject the tissue or foreign body. Yet when this drug is provided the body does not reject the organ, hence the body does not scar to block off and eject the organ when this drug is used. They, using this particular knowledge base, built a hypothesis that a wound would also heal faster and better with the drug. This hypothesis was proven...
