Acne.org Products
haha
Well guys, I propose that from now on, we can plan how to get the formula hydrogel / Duoderm, without having to wait years and years until it goes on sale.
as we know hydrogel / DuoDERM is the solution, now we need to know how to get hydrogel / DuoDERM using homemade formulas or buying similar products.
Let us work
Hey Scarflife 
thanks
DuoDERM gel they sell on that page is what we have discovered recently that regenerate the skin does not scar? or is only one component of the puzzle? its only duoderm whitout the new 'hydrogel'?
I thought that the scientific report, they said that was a tape DuoDERM film dressing that was placed on a special hydrogel gel have recently discovered, i mean , 2 components separates right? ( 1:duoderm film + 2: hydrogel gel) ?
¿maybe we must apply over the fresh scar the new hydrogel gel discover (not on sale yet), and then apply over this, this cain of duoderm FILM? : www.convatec.com/en/cvtus-duodrrngus/cvt-portallev1/0/detail/0/1444/1847/duoderm-dressing-range.html
Please i need more information, its very hard understand english web pages for me.
Thanks all.
Thanks Lapis
¿Any news about Hydrogel? i think this probably are a scam
I hope it will become available and that it will work. But I think it is not likely that this will happen as so many people tried to achieve this before and none have succeeded. I might send them an e-mail too and find out what the current status is.
J'esp¨re qu'il deviendra disponible et cela que cela fonctionnera. Mais je pense qu'il n'est pas probable que ceci se produise comme tant de personnes ont essay© de r©aliser ceci avant et aucune n'a r©ussi. Je pourrais leur envoyer un email aussi et d©couvrir ce qu'est l'©tat actuel. Je ne sais pas si mon Fran§ais est bon parce que j'employais Babelfish cette fois. 
I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just. 
Thanks Lapis
¿Any news about Hydrogel? i think this probably are a scam
I hope it will become available and that it will work. But I think it is not likely that this will happen as so many people tried to achieve this before and none have succeeded. I might send them an e-mail too and find out what the current status is.
J'esp¨re qu'il deviendra disponible et cela que cela fonctionnera. Mais je pense qu'il n'est pas probable que ceci se produise comme tant de personnes ont essay© de r©aliser ceci avant et aucune n'a r©ussi. Je pourrais leur envoyer un email aussi et d©couvrir ce qu'est l'©tat actuel. Je ne sais pas si mon Fran§ais est bon parce que j'employais Babelfish cette fois.
This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.
I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just.
Sun, gerecht etal tested two dextran hydrogels, a 60:40 ratio and a 80:20 ratio. The 60:40 though took longer to resorb than the 80:20. The key is the less time they take to resorb the better healing.
I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just.
You know I was being scarcastic lol.
I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism 
I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just.
You know I was being scarcastic
I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism
Yeah, it strikes me as odd too. It seems all too simple. A bit too simple. It's sort of like for decades doctors have searched for a solution to no avail and now there's these guys from Johns Hopkins who have a hydrogel which does it, right? Which would also mean that all those people (I don't how many!) working for the US government who are trying to find a solution can stop working once this hydrogel comes out as it is the real thing: unlikely.
But we'll see.
This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.
That, in and of itself, is very exciting. But I think that what will happen is that they'll do tests on larger animals and find that for some reason it doesn't work. Or if it does they'll move on to tests in humans and find that it doesn't work then. Or if it does it will only work to a degree and what we'll have is something that is a mere improvement over existing things which won't make people run to the hospital to have it used on them. That's what I'd put my money on.
But, again, we'll see.
I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just.
You know I was being scarcastic
I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism
Yeah, it strikes me as odd too. It seems all too simple. A bit too simple. It's sort of like for decades doctors have searched for a solution to no avail and now there's these guys from Johns Hopkins who have a hydrogel which does it, right? Which would also mean that all those people (I don't how many!) working for the US government who are trying to find a solution can stop working once this hydrogel comes out as it is the real thing: unlikely.
But we'll see.
This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.
That, in and of itself, is very exciting. But I think that what will happen is that they'll do tests on larger animals and find that for some reason it doesn't work. Or if it does they'll move on to tests in humans and find that it doesn't work then. Or if it does it will only work to a degree and what we'll have is something that is a mere improvement over existing things which won't make people run to the hospital to have it used on them. That's what I'd put my money on.
But, again, we'll see.
Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.
Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.
The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?
Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.
The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?
I would say that describes a scaffold. A scaffold to me is a three dimensional framework. Anyway here is a cite
Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.
The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?
I would say that describes a scaffold. A scaffold to me is a three dimensional framework. Anyway here is a cite
http://www.pnas.org/...973108.abstract
Ah, it says so right there on the site you posted that it is a scaffold. Exciting. 
It's not a gel- It's a gelatin sheet designed a certain way to control/stimulate/manipulate the healing process. The Hydrogel-Hydrogelatin sheet is placed over the wound- A sheet of Duoderm is placed over the hydrogel sheet to keep the wound/hydrogel environment covered/clean as well as holding/securing the hydrogel sheet down over the wound.
The youtube video really explains the process involved in making a hydrogel scaffold. I hope more information about the material ingredients/creation of the "Scar Free Hydrogel" comes out. It seems like it could be possible to make it at home. Not possible for everyone, but the lab equipment used to make that sheet in the youtube video doesn't seem to be too complex.
Hello people!
Check out this:
http://www.genome-en...car-tissue.html
April 3, 2012
Gene therapy reprograms heart scar tissue
They're targeting 3 different genes, what do you think about that?
EXC-001 before and after picture:
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Correct me if I wrong - this scar on the right side of the picture is a keloid (the worst type of scar), not a hypertrophic scar? And after 4 doses of EXC-001 scar reduction looks quite good! I think that this is better that Juvista Phase II trials pictures.
EXC-001 was a success in three Phase II clinical trials (because of that Pfizer bought Excaliard), the fourth Phase II clinical trial results will be announced next month (in may 2012).
Excaliards main drug EXC-001 is targeting a protein that is called 'connective tissue growth factor' or CTGF:
http://en.wikipedia.org/wiki/CTGF
And many other biotech companies are targeting the same protein for their anti-scarring drugs (like RXi Pharmaceuticals - company founded by Nobel Prize winner Craig Mello - he received Nobel Prize in 2006 for a discovery of RNAi gene-silencing technology and his anti-scarring drug RXi-109 is based on that technology)
RXi Pharmaceuticals - RXi-109:
[removed]
This is interesting too:
http://apps.research...eting/11000.pdf
University of Florida is seeking for a company interested in commercializing a new drug that targets guess it CTGF!
I doubt that they are all wrong and that they all target the wrong protein.
What do you think about all this?
And does anybody know anything about Excaliards other drugs - EXC-002, EXC-003, EXC-004, EXC-005?
?1304865285
Are they planning to target some other genes/protein besides CTGF with EXC-002/-003/-004/-005? Target #2, Target #3, ect - that doesn't mean anything for me but it would be nice to see them developing 5 different drugs for 5 different genes/proteins that are indetified as the main causes of scarring in humans.