ah yea right, i ordered it once there but it never arrived cause our customs authorities confiscated it (500$ wasted, excellent). and about the excising part: cant you, for the start, make a new wound in normal skin and test it there (thats what i did), to rule out the possibility of remaining scar tissue affecting the healing process negatively? but yea, id be realistic. if it really is supposed to regenerate skin, why doesnt acell provide any pictures of success? because it doesnt. if my product could regenerate the top of a thumb (and again, i think this occurs naturally), id do trials, trials and trials like renovo
ah yea right, i ordered it once there but it never arrived cause our customs authorities confiscated it (500$ wasted, excellent). and about the excising part: cant you, for the start, make a new wound in normal skin and test it there (thats what i did), to rule out the possibility of remaining scar tissue affecting the healing process negatively? but yea, id be realistic. if it really is supposed to regenerate skin, why doesnt acell provide any pictures of success? because it doesnt. if my product could regenerate the top of a thumb (and again, i think this occurs naturally), id do trials, trials and trials like renovo
IMO I think Acell matristem is denatured as in photos weave seen fibrotic encapsulation (the Speivack patent mentions fibrotic encapsulation being proof of denaturing) along with regeneration has occurred. Though to be fair we have seen regeneration with no visible scar to in the odd photo.
Personally I would not touch a denatured ECM. Or anything that is denatured.
Also you mention trialsa
ECM has been approved.
And trials in the main as well as being expensive, can be unwittingly or wittingly manipulated especially before phase 3.
Eg.
Here is something someone wrote about the juvista trial.
http://www.iii.co.uk/investment/detail/?di...amp;action=list
I do not have an opinion either way on what that guy has wrotea But right or wrong, still, his post should make you question everything.
Also you mention trialsa
ECM has been approved.
And trials in the main as well as being expensive, can be unwittingly or wittingly manipulated especially before phase 3.
Eg.
Here is something someone wrote about the juvista trial.
http://www.iii.co.uk/investment/detail/?di...amp;action=list
I do not have an opinion either way on what that guy has wrotea But right or wrong, still, his post should make you question everything.
lol Interesting.
Well on that note, im establishing BiogeneticsXL - the newest and most exciting company on the market and guess what it specialises in! scar revision who wants to buy a few shares
?
selected in house trials have revealed that scars are mysteriously transformed by the strange and wonderful properties of BiogeneticsXL strain 00158s1
oh dear...thanks for the post seabs
Well on that note, im establishing BiogeneticsXL - the newest and most exciting company on the market and guess what it specialises in! scar revisionwho wants to buy a few shares
?
selected in house trials have revealed that scars are mysteriously transformed by the strange and wonderful properties of BiogeneticsXL strain 00158s1
oh dear...thanks for the post seabs
LOL.
BTW I wouldn't put a cent in it. Your company will have no interest in it, the incentive is not there. Though you will use the weasel term 'scarless healing' and no doubt and others may put there money in...
BTW to be a pain in the ass to you . I will state this, scar free healing has been done.
Hi guys,
I have a link to a paper that was published in July that examines the role Avotermin (TGF-I3) has to play following scar revision. Interestingly, the conclusive findings appear to be promising; Mark Ferguson (of Renovo fame, as I am sure you are aware of) is one of the many co-authors and this comes of course at the heels of Juvista's decisive failure at clinical trial #3
What do you guys think?
If someone has institutional access, will you be able to share with us some pictures etc from the paper as we all know the deal clincher is pictures; paragraphs barely say anything!
Hi guys,
I have a link to a paper that was published in July that examines the role Avotermin (TGF-²3) has to play following scar revision. Interestingly, the conclusive findings appear to be promising; Mark Ferguson (of Renovo fame, as I am sure you are aware of) is one of the many co-authors and this comes of course at the heels of Juvista's decisive failure at clinical trial #3
What do you guys think?
If someone has institutional access, will you be able to share with us some pictures etc from the paper as we all know the deal clincher is pictures; paragraphs barely say anything!
I can't believe the weirdness of this... Test after test they've done and now (with the same dosage as before, even) they say it does do a lot of good? I have a hard time believing that!
Nice to see you again, Cambree!
Btw, I also might shoot an e-mail Histogen's way, asking politely about how what's in the pipeline may be of benefit to us. No stalker. haha As they said anyone can contact them anytime.
A few days ago I received a reply from Histogen. In a nutshell, they said that they do not intend to market any anti-scarring product in the near future. Oh well.
Did they explain why not to you?
no the problem is that the powder isnt available anywhere
btw i just cut myself on my pinky. i doubt therell be a scar. lets see how it goes.
or does anyone have scars on their palm or on the sole of the foot? i tell you, i stepped into glass and it bled a lot, yet healed scarless. they should study the palms and soles and find out why it works there.
I have a scar on my left palm from childhood. I ran my hand through the glass door and the scar has been there ever since.
Hi guys,
I have a link to a paper that was published in July that examines the role Avotermin (TGF-I3) has to play following scar revision. Interestingly, the conclusive findings appear to be promising; Mark Ferguson (of Renovo fame, as I am sure you are aware of) is one of the many co-authors and this comes of course at the heels of Juvista's decisive failure at clinical trial #3
What do you guys think?
If someone has institutional access, will you be able to share with us some pictures etc from the paper as we all know the deal clincher is pictures; paragraphs barely say anything!
Yes, please! Sounds like a great article, so I really hope we get some to post more information and pictures.
Hi guys,
I have a link to a paper that was published in July that examines the role Avotermin (TGF-²3) has to play following scar revision. Interestingly, the conclusive findings appear to be promising; Mark Ferguson (of Renovo fame, as I am sure you are aware of) is one of the many co-authors and this comes of course at the heels of Juvista's decisive failure at clinical trial #3
What do you guys think?
If someone has institutional access, will you be able to share with us some pictures etc from the paper as we all know the deal clincher is pictures; paragraphs barely say anything!
I can't believe the weirdness of this... Test after test they've done and now (with the same dosage as before, even) they say it does do a lot of good? I have a hard time believing that!
Nice to see you again, Cambree!
It was a phase II trial, the phase III trial showed it was as good as piss water saline.
BTW the selected photos in the link are not at all impressive IMO.
Hi guys,
I have a link to a paper that was published in July that examines the role Avotermin (TGF-I3) has to play following scar revision. Interestingly, the conclusive findings appear to be promising; Mark Ferguson (of Renovo fame, as I am sure you are aware of) is one of the many co-authors and this comes of course at the heels of Juvista's decisive failure at clinical trial #3
What do you guys think?
If someone has institutional access, will you be able to share with us some pictures etc from the paper as we all know the deal clincher is pictures; paragraphs barely say anything!
Cambree if you click on the pyramid image at the bottom of the article you can see a sequence of 7 slides, some with photos.
Btw, I also might shoot an e-mail Histogen's way, asking politely about how what's in the pipeline may be of benefit to us. No stalker. haha As they said anyone can contact them anytime.
A few days ago I received a reply from Histogen. In a nutshell, they said that they do not intend to market any anti-scarring product in the near future. Oh well.
Did they explain why not to you?
Kind of, sort of they did. They just said that although they certainly believe their "technology" can be used for scar reduction/prevention they have chosen to get a different product realized and approved that doctors can use for surgery.
They do have this other thing that supposedly speeds up recovery after laser surgery but that's about it. And that one also is going to take a long time to get realized.
He was very clear. He basically said "I wouldn't wait for it, if I were you." as it really isn't going to come along any time soon. A scar prevention product from them at least.
Sorry to hear about the scar on your palm.
It was a phase II trial, the phase III trial showed it was as good aspiss watersaline.
BTW the selected photos in the link are not at all impressive IMO.
I missed that. But you're right it's from phase 2! How confusing and strange that they post that now, while the whole thing is already over.
How confusing and strange that they post that now, while the whole thing is already over.
They as in the people from the website Cambree posted a link to.
sounds like that juvista guy is already planning his next scam
im surprised any board would allow him to speak, especially since he lied to so many people for such a long time.
if he came anywhere near my company, id kick him to the curb
lets see how many people fall for his lies this time
i was reading some studies a few days ago and it seems all of them compare a product to a placebo *meaning nothing*. then when they find their product does more than nothing, they get all excited... i mean, why dont you test your product in comparison to established scar products, instead of absolutely nothing, because the last thing we need is another worthless product.
What happened to this thread.
4 years and no results happened. I've been researching since 1999. Renovo's final outcome was absolutely depressing. Never forget Mark Ferguson. Never let him or any of the members at Renovo run another con game. Always be skeptical of everything. Proof is Proof. Theory drives us to find it, but until it's found, that's all it will be, and no one should invest in that.
What happened to this thread.
It was brought back from the dead!
Anyway, yeah, nothing much seems to be going on from which we should expect the fruits to come any time soon. You've got Erkki Ruoslahti and you've got OTR3... But all of that is still some time away from coming to fruition.
I'm not disheartened by Renovo's failure, btw. They just had it wrong. The other ways (e.g. decorin and OTR3's synthetic ECM) seem at least much closer to the real thing i.e. true scarless healing. I'm no expert but I have a good feeling about some of the things that are in the pipeline. It's nice to know that they are ultimately going to come along. And most people here are young so there's a good chance we'll see it in our lifetime (probably when we are still young).
What happened to this thread.
It was brought back from the dead!
Anyway, yeah, nothing much seems to be going on from which we should expect the fruits to come any time soon.
You've got Erkki Ruoslahti and you've got OTR3... But all of that is still some time away from coming to fruition.
I'm not disheartened by Renovo's failure, btw. They just had it wrong.
The other ways (e.g. decorin and OTR3's synthetic ECM) seem at least much closer to the real thing i.e. true scarless healing. I'm no expert but I have a good feeling about some of the things that are in the pipeline. It's nice to know that they are ultimately going to come along. And most people here are young so there's a good chance we'll see it in our lifetime (probably when we are still young).
I know it's coming. I am however very disheartened that a company like Renovo could play the game all the way through 3 CT's, string tons of people along, con tons of investors, and then when it came time to show the horse. There is no horse to show. They walk away with fatter pockets and a big $%^& eating grin.
It means other folks may well do the same. Seems like an easy way to make money if you ask me.
It is however coming, but that's just it, it's not here. Even worse when these "Coming" folks do clinical trials- human trials.
No one here seems to get an invitation...
It takes between 11-15 years to go from stage 1 to stage 3 in clinical trials. That's an awful long time to wait. I waited for renovo, thought my prayers were answered with ACELL. The skingun offers hope but it's an improvement more than an outright cure.
The market for scar elimination is huge! Billions in revenue per year to the company who finds it. I am now in my mid 30's I lost my 20's. I for one am tired of this personal hell. It's very depressing at times.
Flesh is the law.
What happened to this thread.
It was brought back from the dead!
Anyway, yeah, nothing much seems to be going on from which we should expect the fruits to come any time soon.
You've got Erkki Ruoslahti and you've got OTR3... But all of that is still some time away from coming to fruition.
I'm not disheartened by Renovo's failure, btw. They just had it wrong.
The other ways (e.g. decorin and OTR3's synthetic ECM) seem at least much closer to the real thing i.e. true scarless healing. I'm no expert but I have a good feeling about some of the things that are in the pipeline. It's nice to know that they are ultimately going to come along. And most people here are young so there's a good chance we'll see it in our lifetime (probably when we are still young).
I know it's coming. I am however very disheartened that a company like Renovo could play the game all the way through 3 CT's, string tons of people along, con tons of investors, and then when it came time to show the horse. There is no horse to show. They walk away with fatter pockets and a big $%^& eating grin.
It means other folks may well do the same. Seems like an easy way to make money if you ask me.
It is however coming, but that's just it, it's not here. Even worse when these "Coming" folks do clinical trials- human trials.
No one here seems to get an invitation...
It takes between 11-15 years to go from stage 1 to stage 3 in clinical trials. That's an awful long time to wait. I waited for renovo, thought my prayers were answered with ACELL. The skingun offers hope but it's an improvement more than an outright cure.
The market for scar elimination is huge! Billions in revenue per year to the company who finds it. I am now in my mid 30's I lost my 20's. I for one am tired of this personal hell. It's very depressing at times.
Flesh is the law.
If I wasn't so scarred I'd laugh at this (not you 2001, Lapis, scars4life btw). The facts are: scar free healing has been done; And investing in 'scarless' technologies will not bring scar free healing (scarless and scar free are different things). They'll bring scarless healing. I can do scar less healing now, cutting myself more than 2mm and by making sure my wound is clean and moist.
Scam.
Hey guys, something new in the scar regeneration department.
curcumin gel.
http://www.ingentaconnect.com/content/bsc/...000009/art00002
It works after surgical methods. Maybe this is really something to look into.
Neo