My machine indicates low T in the brain, and high T in the prostate. Whenever I try a biotin tablet the pitch of my voice goes up significantly within an hour, and my prostate explodes.

I dont know how you guys feel in the head but my brain feels inflamed if Im to sum it all up - name your problem that goes along with this.

My kinesiologist and I will continue down the path of addressing this via the Dr Wally Schmitt putting out the brain on fire kinesiology pathway

My brain isnt permanently damaged but this inflammation I talk of has been known to kill brain cells etc so I guess it depends on how you define damage. Id like to think if you can deal with the inflammation, other things will reset themselves i.e brain fog, depression, sleep quality, connection with emotions etc etc etc

B1 and b12 stimulates a massive dopamine loss. b2, b5, b6, and biotin destroy me hormonally. Methylfolate 400 is the only b vitamin I can tolerate and it doesn't do much good for me.

My brain feels chronically inflamed. Ginkgo is probably the top herb on the planet for brain inflammation. The problem is so many companies sell a garbage ginkgo product that's been manipulated in a lab, and is completely different from what's found in nature. You can spot this with a percent sign on the back of the ginkgo bottle label. This type of ginkgo stimulates a massive dopamine loss.

Earthborn elements brand ginkgo is different. No lab manipulation. Arrives Saturday.

The best supplement I ever used was Swanson health's old menhaden oil supplement that was discontinued. It was high in saturated fat and dha, and low in epa, which is essentially the fatty acid profile of the human brain. I think this is why I crave foods high in saturated fat. Other menhaden oil supplements are rich in dha and epa, which is no good for me.

Chicken stock aka bone broth. My joints absolutely love the stuff. My brain hates it. Why? Because it's loaded with glycine. What does glycine do? It stimulates dopamine release. My hope is that low dose trazodone can bring some much needed stability to my brain, and that ginkgo can have some additive benefits, possibly reversing any possible negative effects from trazodone use. Studies have shown Ginkgo to reverse antidepressant induced side effects.

Adding arginine to the mix as well. Arginine and ginkgo mornings, low dose trazodone nights. Will see.

15 hours ago, Thomas76 said:

My machine indicates low T in the brain, and high T in the prostate. Whenever I try a biotin tablet the pitch of my voice goes up significantly within an hour, and my prostate explodes.

High Testosterone in the prostate is related to Biotin. The T is trapped and can't get out. There was a study that showed this. The lack of biotin affects the vasculature and or mucosa and doesn't let the testosterone travel to the body. Your experience almost confirms this. There is definitely something there. Can't find the abstract, just the title, but that's the gist as I remember it.

Quote

Klinefelter's syndrome : hypogonadism, abnormal carbohydrate metabolism. It it a result of biotin deficiency ?

• PMID:7289915

15 hours ago, TrueJustice said:

My brain isnt permanently damaged but this inflammation I talk of has been known to kill brain cells etc so I guess it depends on how you define damage. Id like to think if you can deal with the inflammation, other things will reset themselves i.e brain fog, depression, sleep quality, connection with emotions etc etc etc

I agree with this approach. Biotin deficiency literally causes inflammation.

Quote

Biotin deficiency enhances the inflammatory response of human dendritic cells

• Free PMC article

Abstract

The water-soluble biotin (vitamin B7) is indispensable for normal human health. The vitamin acts as a cofactor for five carboxylases that are critical for fatty acid, glucose, and amino acid metabolism. Biotin deficiency is associated with various diseases, and mice deficient in this vitamin display enhanced inflammation. Previous studies have shown that biotin affects the functions of adaptive immune T and NK cells, but its effect(s) on innate immune cells is not known. Because of that and because vitamins such as vitamins A and D have a profound effect on dendritic cell (DC) function, we investigated the effect of biotin levels on the functions of human monocyte-derived DCs. Culture of DCs in a biotin-deficient medium (BDM) and subsequent activation with LPS resulted in enhanced secretion of the proinflammatory cytokines TNF-, IL-12p40, IL-23, and IL-1 compared with LPS-activated DCs cultured in biotin-sufficient (control) and biotin-oversupplemented media. Furthermore, LPS-activated DCs cultured in BDM displayed a significantly higher induction of IFN- and IL-17 indicating Th1/Th17 bias in T cells compared with cells maintained in biotin control or biotin-oversupplemented media. Investigations into the mechanisms suggested that impaired activation of AMP kinase in DCs cultured in BDM may be responsible for the observed increase in inflammatory responses. In summary, these results demonstrate for the first time that biotin deficiency enhances the inflammatory responses of DCs. This may therefore be one of the mechanism(s) that mediates the observed inflammation that occurs in biotin deficiency.

Very interesting info monster. I may be different from other victims. My biofeedback machine currently indicates biotin and inositol as the least recommended vitamins for both my brain and prostate.

I'm starting to think that maybe accutane calcified the pineal gland, which is where serotonin converts to melatonin, resulting in chronically high serotonin and chronically low levels of melatonin. I tested high in 5hiaa several years ago. My 5hiaa was off the chart high.

Think about it. Melatonin plays a major role in brain, gut, gallbladder, and prostate health. Not enough systemic melatonin and all those areas suffer. My current program is essentially pineal gland decalcification. Unfortunately my machine cannot scan the pineal gland. The closest my machine can come to that is the pituitary and hypothalamus. Tonight's herbs include Mucuna and noni. Earthborn Ginkgo arrives tomorrow, and Chaga arrives Sunday. Below is a link about pineal gland decalcification.

https://animamundiherbals.com/blogs/blog/decalcify-your-pineal-gland-with-these-herbs

Could be on to something good there Thomas!!

To loop back around, Im wondering if my need to take magnesium is because of this calcification throughout the body?

magnesium competes with calcium, stands to reason if youre low in magnesium that calcium might take over.

I think Ive tried supplementing biotin before, might try it again, Ive definitely had thinning hair issues over last few years so it couldnt hurt.that I know of anyway

On 6/10/2022 at 1:25 AM, MonsterDiesel said:

Cancer cells feed off of whatever normal cells use to thrive. Don't feed the tumors. I've been out of this conversation for a while, what's going on? You have benign colon tumors? Did they test them for HPV?

Realized this myself. I've used Biotin on and off but am now sticking with it and I'm getting positive effects.

I'm going to try and get to the bottom of this Biotin issue. I think I've had a 20 year deficiency that was caused by Accutane. I have all the signs and symptoms and using Biotin is making me feel better. I'm going to stop using it today, wait a week, then test Biotin levels, and biotinidase enzyme levels. I already did the genetic test for biotinidase and it was negative so I wasn't born with this problem.

Yes was removed and tested to be benign.

hpv? I'm not gay.

Have to be checked yearly for rest of life.

So I guess ill find out if 50,000 iu daily of retinyl palmitate is preventing tumors or encouraging them.

24 minutes ago, Calcified said:

 

So I guess ill find out if 50,000 iu daily of retinyl palmitate is preventing tumors or encouraging them.

What's your rationale for using such a high dose? Careful you dont give yourself hypervitaminosis a. Have you tested your vitamin a levels? You can order labs online without a doctors visit? Also, the more A you take in, the more D and K and other nutrients you'll need in proportion.

https://www.aidsmap.com/news/jun-2008/asymptomatic-anal-hpv-infection-more-common-thought-heterosexual-men

I'm with monster on the retinol intake. Blood tests unfortunately are not accurate for hypervitaminosis A. That requires a tissue sample.

@MonsterDiesel

@Thomas76

Ok, I'm going to say what I do and why, but this for my needs.

I TAKE NO RESPONSIBILITY FOR WHAT I DO CONSUME AND ANYONE WHO COPIES ME.

I take high dosages as it's what I need to live a more normal life.

I take regular tests with a doctor.

My body breaks down vitamin A way to fast.

High levels fix my hair, skin and raise my testosterone levels to more normal levels.

I can feel it's saturation in my tissues.

Vitamin A has a 12 day half life, this is not how it works in me, I'm lucky to get 2 days and then deficiency comes back.

Yes I had tumors but did RA prevent them from being cancerous everything points to a possible yes.

Did RA deficiency make them grow, huge possible yes.

TRUTHFULLY, I TOLD YOU GUYS ABOUT MY COLON ISSUES TO SAVE YOU FROM THE BULLET I DODGED.

Use Google, retinoic acid prevents bowel tumors from growing.

Talks to your doctors get a colonoscopy, you can have tumors without symptoms.

If you think you got prostate issues it could be a tumor near there putting pressure in that area.

IM NOT A DOCTOR, I KNOW NOTHING.

I don't come here and say you need this or that, never will.

AGAIN, DONT DO WHAT I DO, TALK TO A DOCTOR.

This shows how different we all are. I crave carrot juice, i could never get sick of it, but I believe monster said he had major issues with foods such as carrot juice. I despise retinol, I react horribly to it, yet calcified seems to crave it. Monster seems to crave biotin, while my body despises it. The question is, could a calcified pineal gland with serotonin excess and melatonin deficiency be a universal source of all our issues?

When I put the biofeedback machine in auto mode, it almost always zeroes in on my prostate. Benign adenoma, prostatitis, and bph all show up at different times. Sometimes m hominis and ureaplasma infections show up. When the machine goes all the way down to the DNA level, it says I have an issue with acetylserotonin o methyltransferase. Where is the major site of acetylserotonin o methyltransferase in the human body? The pineal gland. Could the pineal gland be calcified post accutane to the point that this enzyme is seriously impaired, and my prostate has simply been the organ that's taking the brunt of the punishment from a problem that stems from my pineal gland? Maybe.Ginkgo arrived today, Chaga and moringa leaf arrive tomorrow, to add to the Mucuna and noni.

https://pubmed.ncbi.nlm.nih.gov/34746997/

Another thing i should mention, the machine indicates that angiotensin I and ii are consistently high for me. Sarcoidosis is an underlying cause for high angiotensin. What hormone has been shown to treat chronic sarcoidosis? You guessed it, melatonin. TJ has mentioned chronic cardiovascular issues post accutane. High angiotensin is a primary cause of cardio issues. Will be conducting a comprehensive biofeedback scan Monday morning and post what I find.

Melatonin also shows powerful antitumor effects. Could it be that calcified has rectal tumors due to a melatonin deficiency, from a calcified pineal gland?

https://www.straighthealthcare.com/cytochrome-p450-3a4.html

https://pubmed.ncbi.nlm.nih.gov/19356072/

I've decided against a multi herb approach in favor of earthborn ginkgo only. Took the first dose of ebgb earlier tonight and major action happening with the liver. Lots of noise/metabolic activity.

Take a look at the above links. One shows accutane as a substrate of cytochrome p450 3a. The other link shows ginkgo as a strong inducer of cytochrome p450 3a. I've tried multiple brands of ginkgo throughout my life and they all failed miserably, mainly because they were all standardized extracts. Earthborn brand is not a standardized extract. It is whole herb ginkgo, which is ginkgo in it's correct, natural form...the form the body needs it to be in to heal. Will report any progress as it comes.

Thomas76 when i started retinyl palmitate, my triglyceride and cholesterol levels went through the roof, have a feeling it was the liver releasing the fat from it.

Retinyl palmitate does increase serum inflammatory markers but not a huge increase, yet visually I have less inflammation.

7 hours ago, Calcified said:

Thomas76 when i started retinyl palmitate, my triglyceride and cholesterol levels went through the roof, have a feeling it was the liver releasing the fat from it.

Retinyl palmitate does increase serum inflammatory markers but not a huge increase, yet visually I have less inflammation.

An ultrasound will tell you if you have any degree of fatty liver. Worth nothing that vitamin a tox will also cause fatty liver

2 hours ago, MonsterDiesel said:

An ultrasound will tell you if you have any degree of fatty liver. Worth nothing that vitamin a tox will also cause fatty liver

 

Vitamin A causes fatty liver? Who Says this?

https://pubmed.ncbi.nlm.nih.gov/645903/

It's always felt like Ive been pushing something around from one body part to another body part. Maybe that something is not accutane, but rather pathogenic bacteria. Studies show that chronic UTI can cause brain issues. Same thing goes for intestinal dysbiosis. My current protocol addresses 3 key areas...brain, gut, and prostate. Earthborn Ginkgo for the brain, kyolic original for gut microbiome balance, and Himalaya herbals Prostacare for the prostate. A cheaper alternative to Prostacare would be source naturals swedish flower pollen. Will see what happens.

Trying Himalaya livercare with earthborn Mucuna. Will report back later.

It's been two weeks after taking mife for me now. I feel different, have a better mood, but not cured. I feel like I'm improving every day a little bit since cessation. I was struggling before taking with severe dandruff, now it is better and my skin is producing some oil right now. Will report back. The guy cured said he really felt the difference after 4-6 weeks.

On 6/12/2022 at 8:05 PM, Calcified said:

Vitamin A causes fatty liver? Who Says this?

Too much vitamin A does. You really should test your levels and check liver enzymes.

12 hours ago, Thommy280495 said:

It's been two weeks after taking mife for me now. I feel different, have a better mood, but not cured. I feel like I'm improving every day a little bit since cessation. I was struggling before taking with severe dandruff, now it is better and my skin is producing some oil right now. Will report back. The guy cured said he really felt the difference after 4-6 weeks.

Mife? As in mifepristone?

Testing biotinidase enzyme levels tomorrow. Will report as soon as I get results.

To all suffering still and future unfortunate cases I hope you will all stay strong and never give up. The fact we were all damaged by accutane poison was a sad reality check to the evil that exists in this world. I took accutane when I was 16(now 28) and it damaged my overall physical health in many ways such as having no energy, brain damage (I have seen brain scans of people who took accutane and it kills parts of the brain.)

This is not surprising because accutane is a chemotherapy drug and chemo directly kills all cells.) hurting joints, and bad night vision. But by far the worst part about it for me was that it destroyed my sexual function and sexuality completely. Accutane was chemical castration for me and many others. And I know for a fact accutane did it because I experienced the change during accutane and I used to be the complete opposite. I feel this poison accutane kills off many cells and does the whole body damage because it is chemotherapy, and causes many health issues.

Roche and anyone else involved with the production and distribution of this evil poison should be sued and prosecuted to the full extent of the law. We had our normal lives stolen from us and the least we deserve is to be paid for this damage. The damage is permanent and well never be the same. Fast forward 12 years I feel okay overall and have found methods to cope and heal. I have accepted that Ill never have my sexuality and function back to normal, but at least I am healthy overall. I eat a healthy diet, get moderate exercise and sunshine, and do my best to take care of myself.

I also like to vaporize cannabis a lot, and have done so for nearly 10 years. I can tell you I believe it is medicinal and has helped me get better post accutane. I would recommend others to use cannabis medicinally because it can help a lot (But vaporize, dont smoke. Smoking is bad and doesnt give medicinal value.) Also I avoid dispensaries, most dont sell real product its like gmo weed. Grow your own or find a reputable source. Also the biggest thing that has helped me get rid of acne was cutting out all dairy from my diet. When I used to eat a lot of dairy my acne was all over. Now I dont get much acne,although sometimes I still do.

Pretty sad how after ruining my life at 16, accutane didnt even get rid of my acne! Thanks Roche (Cockroaches). Anyhow I wish you all the best and I hope we can continue making progress and one day get justice for this evil BS.

Hello guys,

I wanted to share with you my current life situation as I am considering another Accutane round (this would be the third). I took the first two rounds at about 15 and 17 years old and now I am 27 years old and I am considering prescribing the next round, because honestly this is the only medicine that has helped me over the years. After reading a few pages on this thread, I think it probably won't be a best solution for my overall health state. I used to suffer from really severe acne when I was a teenager. I also suffered from big mental problems, but even before Accutane. I was also thinking about suicide. However, this "cure" helped me so much that I didn't have to deal with acne until I was 27 years old. However, the current situation is completely different. For a year or two I have been suffering from relatively large acne (approx. 5 - 20 pimples on my face), unfortunately even the big and long lasting ones. Now I'm trying benzyol peroxide 5%, when I know that it has helped me relatively before, but I've been on it for 3 weeks and I don't see any good results. Only worsening, red spots, itching (I know its relatively normal but I would expect at least some good results).

What would you recommend to me in my current situation? I honestly don't want to go to Accutane anymore, but it was really the only thing that helped me and I didn't notice any side effects in terms of sexual appetite or mental health problems. On the contrary, I currently have suicidal thoughts, but again that is from how my face looks like now. I'm at the bottom and considering the best solution for myself. I'm have upcomming appointment to an endocrinologist and I'll see what results I get from him. But I don't expect him to tell me or recommend from him what would help me.A drowning man will catch at a straw as they say.

I am just seeking for other people opinions, because this acne sh*t is destroying my life, my mental health, my relationships and every other aspect of my life. I also stutter so combination of these two will drives me to the edge sooner or later...

Thank you!

I'm 30 years post accutane and im ok with gluten, corn, and lactose free dairy. Soy, artificial sweeteners, lactose, and caffeine are major problems for me. I have major negative reactions to cbd in the form of anger. I realize cbd is different from marijuana. I've read that marijuana lowers testosterone so Ive avoided it.

Lactose free skim milk helps me to stay somewhat hydrated. I'd be worse off without it. Currently supplementing with Himalaya herbals dermacare and livercare, along with glucosamine and chondroitin. Naturecrazy YouTube guy says the drug is trapped in our skin. The hope is if that's true, that Himalaya dermacare can detox it out of the skin and send it to the liver for processing. Glucuronidation is a major part of accutane removal, and glucosamine and chondroitin provide glucose, the precursor needed for Glucuronidation.