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Normally if I take livercare or glucosamine by itself they cause a massive dopamine loss. When I include dermacare, there is no dopamine loss, only a strong sense of mental peace. Prostate's not liking this combo so far but is that because accutane is being detoxed out of the skin, and the prostatic inflammation is only temporary during the accutane skin detox? I'm not waiting around to find out. Added Himalaya Prostacare and also immunocare to help with bone marow and lymph detox. Dropping the glucosamine.
On 6/16/2022 at 7:01 PM, Thomas76 said:Naturecrazy YouTube guy says the drug is trapped in our skin. The hope is if that's true, that Himalaya dermacare can detox it out of the skin and send it to the liver for processing.
Proof? If true, then it's trapped in the layer of subcutaneous fat. The only real way to address it is to get your body fat% as low as possible, even in the single digit.
How would dermacare detox it and how will you know if it worked?
I used to approach tane healing taking supplements in the hope something would make me feel better. That's not exactly right. Tane affected many different systems in our body and it's best to guide this with what the research says, rather than our subjective feeling.
I love that there's a lot of people here trying different things but I did the blind try this and that for YEARS (10-15). All I did was waste time and money..
On 11/17/2020 at 2:47 AM, Doctorcolumbus said:Metformin (or Berberine) - This will be my stack for the next months
Did you take it? Experiences?
On 11/20/2020 at 9:17 AM, Quinc said:to add, isotretinoin doesnt solely bind to RAR or RAX receptors, theres speculation about FOXO1 interacting with isotretinoin and causing the adverse effects were all familiar with. Isotretinoin seems to upregulate expression of FOXO. Ive looked into compounds that downregulates it and found that metformin could potentially help here. Might be something to look into. Here are the relevant articles:
I used metformin for two months and I think there is something to FOXO. After Tane, any supplement I took (vitamin C, Fish oil) would cause horrible side effects and I gained no benefits from using them.
While being on metformin, I found I tolerated these and many other supplements just fine and in fact, was able to enjoy some benefits. For example, Vitamin C and fish oil didn't cause lethary, b-complex vitamins didn't make me feel like shit and biotin gave me tons of energy, increased muscle tone and did a bunch more things for me. I stopped metformin and again, supplements make me feel ill.
What if, in addition to addressing the deficiencies caused by accutane, we also need to target the FOXO pathway at the same time? Not talking cure here, but rather a long term strategy\therapy that will allow us to be functional again and feel better.
Has anyone looked into Candida in the brain??
We laughed years ago when someone said its Candida but Im curious if this school of thought should be taken more seriously or not
so far regular naturopathy hasnt helped with this crusty persistent ear itch Ive had now for a few years, I wonder if I need something stronger in the way of antibiotics to treat it and I also have a sneaking suspicion it might be in my brain as well. Google it - you can get Candida infection in the brain too. We all know tane wiped the gut, it would be easy to see how Candida took hold after that yeah
The only other theory is that this itch is simply lymphatic that is still clearing which Ive worked on a lot. Ill try to push next kinesiologist session to see if I have Candida in the brain
This might call for a regular GP visit and a course of antibiotics or whatever they put you on for chronic Candida
On 6/15/2022 at 9:51 AM, MonsterDiesel said:Too much vitamin A does. You really should test your levels and check liver enzymes.
Mife? As in mifepristone?
Testing biotinidase enzyme levels tomorrow. Will report as soon as I get results.
Blood tests have been normal.
Liver bloods are perfect, maybe it's just me like this, bear in mind I was on accutane for too long and wasn't very dry at the end, so I may have somehow become deficient in my organs and tissue but not in serum.
Don't know how else to put it.
I guess my body thought I was going to be on accutane forever and just adapted.
One day I may regret taking toxic amounts of retinyl palmitate.
3 hours ago, Calcified said:
Blood tests have been normal.
Liver bloods are perfect, maybe it's just me like this, bear in mind I was on accutane for too long and wasn't very dry at the end, so I may have somehow become deficient in my organs and tissue but not in serum.
Don't know how else to put it.
I guess my body thought I was going to be on accutane forever and just adapted.
One day I may regret taking toxic amounts of retinyl palmitate.
Fatty liver doesn't show up on blood tests. You have to do an abdominal ultrasound to see it. I say, take a break from it, go to your doctor and get tested. There is literally no justification for taking such high amounts of retinyl palmitate over a long time. You'll give yourself cirrhosis and liver failure. We don't want that for you, buddy.
29 minutes ago, MonsterDiesel said:Fatty liver doesn't show up on blood tests. You have to do an abdominal ultrasound to see it. I say, take a break from it, go to your doctor and get tested. There is literally no justification for taking such high amounts of retinyl palmitate over a long time. You'll give yourself cirrhosis and liver failure. We don't want that for you, buddy.
Problem is I had fatty liver diagnosis prior to taking retinyl palmitate, unfortunately common for us.
I know what I'm doing is insane but life is much harder without it.
I have terrible skin problems like dermatitis and folliculitus without taking it. Which started a year after accutane, folliculitus first then dermatitis. At first I thought it was just mpb, but over years it just gets more angry and inflamed with boils. I have a customer service job where I'm not comfortable being covered in scalp boils. It gets excessive at times.
I still don't get much facial acne, thanks to Accutane I guess, it's all scalp now.
Have been to dermatologist and they give me creams containing retinoids, which help too. A dermatologists told me not to take vitamin A, due to increased chances of calcification, as similar to Accutane.
My other option is antibiotics forever. I'm avoiding as I read it increases colon tumors.
It's not just a dryness, it's like my body doesn't try to react so much to oils, soaps, shampoo etc. So less skin inflammation, like the body not as much in fight mode.
But yeah you right I may be absolutely killing my liver.
Some days I only take 25000iu, but it starts to happen again.
6 hours ago, Calcified said:Problem is I had fatty liver diagnosis prior to taking retinyl palmitate, unfortunately common for us.
Phosphatidylcholine is what reverses fatty liver. It's needed by VLDL molecules to transport fatty acids out of the liver. I would consider using this. Biotin also repairs the liver. I found a study detailing the effects a week ago. I was pretty impressed, tbh. Both of these are decreased (permanently) by accutane. Biotin insufficiency is also implicated in dermatitis and folliculitis.
9 hours ago, MonsterDiesel said:Phosphatidylcholine is what reverses fatty liver. It's needed by VLDL molecules to transport fatty acids out of the liver. I would consider using this. Biotin also repairs the liver. I found a study detailing the effects a week ago. I was pretty impressed, tbh. Both of these are decreased (permanently) by accutane. Biotin insufficiency is also implicated in dermatitis and folliculitis.
Will look into Biotin, at first glance I note it increases sebum which may be a poor outcome for myself.
I tried b12 once and it was good at first but my folliculitus got worse due to increased sebum I presume.
On 6/14/2022 at 7:37 AM, Thommy280495 said:It's been two weeks after taking mife for me now. I feel different, have a better mood, but not cured. I feel like I'm improving every day a little bit since cessation. I was struggling before taking with severe dandruff, now it is better and my skin is producing some oil right now. Will report back. The guy cured said he really felt the difference after 4-6 weeks.
We are rooting for you man!!!
Dermacare herbs facilitate the transport of foreign materials from the skin to the bloodstream. I no longer feel this is important for us. I believe a strong and healthy liver function is the most important aspect of recovery.
There are two phases of liver detox, phase 1 and phase 2. Phase 1 involves cytochrome p450, which is a heme iron based enzyme. Phase 2 involves glucuronidation of accutane, which attaches glucuronic acid to accutane for removal. Glucuronic acid is derived from glucose. I believe the body is constantly starving for adequate amounts of iron and glucose to complete the detox process, it never has enough of either, and so accutane remains trapped in the body. Once you give the body the extra iron and glucose it needs, the detox process can finally occur.
Currently my daily program involves 3 things. Beef spleen for the heme iron content to support cytochrome p450, defatted beef liver to support liver recovery, and glucosamine/chondroitin without msm, to support joints and glucuronidation. Some vitamin c gummies here and there, but that's not as important as the other 3. A cheap iron tablet might be ok in place of the beef spleen, which is a bit pricey. Codeage, ancestral supplements, and Dr Ron's all produce high quality beef spleen. Universal uniliver and Swanson health are 2 excellent options for defatted beef liver.
I've also incorporated international delight mocha flavored coffee to help with liver recovery. I used to avoid all caffeine due to horrific effects, but the above 3 supplements seem to have eliminated my negative response to caffeine. Will keep the board posted.
Candida overgrowth is most likely an issue for all of us, in both the gut and the brain, and likely the skin as well. I believe once healthy liver function is restored, candida levels will fall back down to normal levels.
I'm with monster on the high retinol intake issue. Cod liver oil and Whole beef liver always caused me issues due to the retinol content. With defatted beef liver, there are no retinol issues because the fat and retinol have been removed. If I try defatted beef liver without the iron rich beef spleen and glucosamine, I react badly in a different way than whole beef liver. If I do the defatted beef liver with the beef spleen and glucosamine, no bad reaction so far.
Calcified if I were you I'd replace the retinol pills with daily carrot juice intake. Carrot juice is loaded with beta carotene, a much safer approach for vitamin A supplementation. I do notice some minor mental and physical benefit from regular carrot juice intake. Bolthouse farms carrot juice is excellent.
Calcified i believe your liver has lost its ability to transport vitamin A to your skin. I think if you can resolve your liver function, vitamin A and fatty acid transport to your skin will be restored. Will see how my program goes over the coming weeks.
Ill put this one out there, some will debate it but none the less.
So during yesterdays kinesiology session, I wanted to focus on getting an answer about Vit A still being trapped in my brain, 9 months ago wed discovered this during a session but I wanted to come back to it as a matter of focus this week.
The answer is yes, Vitamin A is in each hemisphere and when I asked is it synthetic A, the body responded yes - no prizes for guessing what that might be.
Other key points and where to go from here:
I have other more pressing things to fix namely bad bacteria to get rid of in the gut and large intestine, cant remember the names. Practitioner said, youre body doesnt care about getting rid of Accutane from 20 years ago when its fighting off these other viruses and bacteria
He also said when I pointed out that getting rid of Vit A from my brain might be challenging given its fat soluble and tricky to remove. He said it will be easier to remove as we continue to control inflammation, organs are inflamed etc due to these lingering viruses/bacteria - immune system responds to them in this way
What can I say, could only be a small amount and enough to cause my brain issues but tane still present in my body 23 years later.
FYI - he has me on Melia Supreme to rid these viruses/bacteria. Other people he might use Mastic Gum but my body said Melia
Also just add..
Ive mentioned this before, practitioner has had me on a product called Activator X which has Vit A, Vit K2 and D3
I asked, wouldnt taking this be harmful given what Ive still got trapped in brain. He said no not always the case. Often taking the real vitamin can help the body
So yeah, cant speak for everyone but avoiding Vit A is not the answer for me.
Plenty of ways to get Vit A though, not just via supplements, I like Activator X as its a good balance with the other fat soluble vitamins.
The practitioner saying that the body doesn't care about getting rid of accutane hit home with me big-time. That's exactly what it's always felt like, as if my physical body is completely ok with being sick from accutane and has no real desire to fix itself. So frustrating.
I think this is why I crave carrot juice so much. My body wants true vitamin A, and it realizes that carrot juice is it's best and safest bet to get what it wants.
One thing I need to add. When I would load up on non decaf mocha coffee in the past, it would make me extremely angry. Arginine and CBD are two supplements that would also make me extremely angry.
I've consumed a significant amount of non decaf mocha coffee in the past 24 hours and no anger. Why? Well, I've been using the defatted beef liver, Himalaya liver care, iron, and glucosamine.
I've always craved not only carrot juice but also mocha coffee drinks, but always avoided the coffee up until now because I didn't like the agitation and anger.
My thought is this. Does the high orac, caffeine rich mocha coffee stimulate fat burning, which releases accutane from fat cells into my bloodstream, which creates anger unless I'm helping my liver with defatted beef liver and Himalaya livercare.
Here's another thing. When I first bought the biofeedback machine it would always automatically zoom in on my eyes and said I had Bornholm eye disease. I started supplementing with whole beef liver despite the agitation I got from it and soon the machine no longer zeroed in on my eyes and that disease was gone. It sounds as though accutane is trapped in the body, and when I started getting the true retinol from the whole beef liver my body prioritized my eyes to receive the retinol first.
If I take heme rich beef spleen by itself, I get a splitting headache. If I take it with liver supportive herbs or defatted beef liver, no headache. My thought is the heme iron was stimulating phase 1 cytochrome p450 of your detox system, you were ignoring phase 2 of your detox system, and thus the dizziness. If you had used something like defatted beef liver and or Himalaya liver care and maybe some glucosamine to help with phase 2 detox, the dizziness likely would not have occured.
19 hours ago, Thomas76 said:I'm with monster on the high retinol intake issue. Cod liver oil and Whole beef liver always caused me issues due to the retinol content. With defatted beef liver, there are no retinol issues because the fat and retinol have been removed. If I try defatted beef liver without the iron rich beef spleen and glucosamine, I react badly in a different way than whole beef liver. If I do the defatted beef liver with the beef spleen and glucosamine, no bad reaction so far.
Calcified if I were you I'd replace the retinol pills with daily carrot juice intake. Carrot juice is loaded with beta carotene, a much safer approach for vitamin A supplementation. I do notice some minor mental and physical benefit from regular carrot juice intake. Bolthouse farms carrot juice is excellent.
Calcified i believe your liver has lost its ability to transport vitamin A to your skin. I think if you can resolve your liver function, vitamin A and fatty acid transport to your skin will be restored. Will see how my program goes over the coming weeks.
So true, vitamin A and my skin is broken somehow, it's weird.
Beta carotene unfortunately scares me as i think I saw some study where it increased cancer or something.
Have really been thinking about what monster said about a liver ultrasound, results would be interesting,see if the fat is still there.
The cancer study involved synthetic trans beta carotene supplements, which are garbage. The cancer issue could not be duplicated with natural beta carotene supplements. I've used synthetic and natural beta carotene supplements. always reacted badly to the synthetic. Natural bc always produced minor improvements but nothing major. Carrot juice is whole food beta carotene which has anti cancer properties. Pro cancer effects always come from synthetic isolates, never from whole foods. I guarantee after one sip of Bolthouse farms carrot juice you'll be hooked. Highly addictive.
I've realized my body wants the retinol rich whole beef liver so I went back to it, but am also including himalaya livercare and arginine.
18 hours ago, Thomas76 said:The cancer study involved synthetic trans beta carotene supplements, which are garbage. The cancer issue could not be duplicated with natural beta carotene supplements. I've used synthetic and natural beta carotene supplements. always reacted badly to the synthetic. Natural bc always produced minor improvements but nothing major. Carrot juice is whole food beta carotene which has anti cancer properties. Pro cancer effects always come from synthetic isolates, never from whole foods. I guarantee after one sip of Bolthouse farms carrot juice you'll be hooked. Highly addictive.
I've realized my body wants the retinol rich whole beef liver so I went back to it, but am also including himalaya livercare and arginine.
Ok , I'm going to give the carrot juice a go so you think 500ml should get me about 50,000iu a day or do I need more?
I would drink carrot juice daily. Bolthouse farms is my fave. Id also do mocha coffee daily. International delight is the brand I'm using. I would not try to meet any minimum or maximum amount. I would listen to what your body wants as far as amount goes.
But really, I feel that non defatted beef liver pills combined with Himalaya livercare or organic India liver kidney formula is what's needed to recover from accutane. I added the arginine for sexual health recovery.
Himalaya livercare or organic India liver kidney formula is what enables your body to absorb beef liver's retinol content while simultaneously detoxifying accutane out of the body. it can't be just whole beef liver or just the herbal liver formula. It really needs to be both, daily.
On 7/16/2015 at 5:54 PM, tryingtohelp2014 said:D-limonene a natural PPAR agonist? Read the first few paragraphs on PPAR and LXR
D-Limonene has been shown to clear the gall bladder and get the bile flow moving as well. It also activates phase I and II detoxification enzymes.
re
Did you use limonene? Seeing the same research you posted some years ago. What was your experience using it? I like the liver detox angle..
I was considering d limonene but didn't order it yet. Yes it seems great for phase I and ii liver detox. I think the reason calcified was able to tolerate such large amounts of retinol is because very little of it was being absorbed. Cutting back to 5k iu retinol daily and taking an iron tablet at the same time may be a more economical approach. I believe the iron tablet would vastly improve bile flow, enhancing retinol absorption, allowing a much lower dose of retinol to be taken.
My protocol starting tuesday is whole beef liver for the retinol content, beef spleen for the iron content, beef intestine to heal the gut, beef brain, and beef prostate. the beef prostate doesn't arrive until Tuesday. I believe accutane is radioactive and that it is indeed migrating around to various tissues. If I take beef intestine the machine indicates a clear gi tract but worsening tissues in other areas. If I take beef brain, the machine indicates improved brain but worsening tissues in other areas. Same thing with beef liver. Improved liver but worsening tissues in other areas. My thought is if I hit every area simultaneously, accutane will have nowhere to go but the toilet.