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On 3/3/2021 at 10:09 PM, IhateAccutane said:7 years passed since my last pill.
I took 40mg/day for two months in 2014 Jan/Feb.
Stopped after I realised that I could not achieve erection.
Other symptoms started after I stopped Accutane.This is the list of my problems ever since:
- ED: Betterconnection between penis and brain comparing to last years but never like it used to be.
- Shrunken genitals
- 10%-50%Libido(Sometimes better)
-Usually dead flaccid
- No pleasure during ejaculation. (Sometimes better)
- Tinnitus: still there, biggest concern after ED.
- Vision problems: Floaters are gone by 99%. But I am still night blinded and have some visual snow and double vision.
- Tremors: Gone
- Weak urine: Still there (sometimes better)
- Hair condition: I dont have menopause hair anymore.
- Dry eyes, nose, mouth: I never had these.
- Panic attacks, anxiety, suicidal state: Gone
- Energy: Better, just as pre accutane but I aged so may be a little bit less.
- Flexibility: Improved, %80I changed and I never liked my new settings.
But besides these damages that I have to live with, I have a normal life, I go to work, I enjoy good food, I drink, I listen to music, I enjoy good conversation with friends.
8 years passed since my last pill.
I took 40mg/day for two months in 2014 Jan/Feb.
Stopped after I realised that I could not achieve erection.
Other symptoms started after I stopped Accutane.
This is the list of my problems ever since:
- ED: Still poor connection between penis and brain.
- Shrunken genitals
- 10%-50%Libido
-Usually dead flaccid
- No pleasure during ejaculation. (Sometimes better)
- Tinnitus: still there, biggest concern after ED.
- Vision problems: Floaters are gone by 99%. But I am still night blinded and have some visual snow and double vision.
- Tremors: Gone
- Weak urine: Still there (sometimes better)
- Hair condition: I dont have menopause hair anymore.
- Dry eyes, nose, mouth: I never had these.
- Panic attacks, anxiety, suicidal state: Gone
- Energy: Better, just as pre accutane but I aged so may be a little bit less.
- Flexibility: Improved, %80
I changed and I never liked my new settings.
But besides these damages that I have to live with, I have a normal life, I go to work, I enjoy good food, I drink, I listen to music, I enjoy good conversation with friends.
https://www.innate-nutrition.com/blog/accutane
found this link... she has found what i found years ago.
2 hours ago, tryingtohelp2014 said:https://www.innate-nutrition.com/blog/accutane
found this link... she has found what i found years ago.
gotta wonder why many went down the path of anti Vit A diet??
I found high copper years ago in a hair mineral test.
Ive just started to take Vit A in a combination with Vit D & K.
As my kinesiologist says, the very thing that shows up stressing the body initially, can often be the very thing that you actually need - in my case, thats Vit A
Be interesting to test copper again as it has been some time. I suspect though as the report suggests, once A goes up, this should balance Iron and hopefully also copper. The other thing to consider is Zinc
8 hours ago, TrueJustice said:gotta wonder why many went down the path of anti Vit A diet??
I found high copper years ago in a hair mineral test.
Ive just started to take Vit A in a combination with Vit D & K.
As my kinesiologist says, the very thing that shows up stressing the body initially, can often be the very thing that you actually need - in my case, thats Vit A
Be interesting to test copper again as it has been some time. I suspect though as the report suggests, once A goes up, this should balance Iron and hopefully also copper. The other thing to consider is Zinc
How much and what type vit A you taking? If you don't mind me asking.
I'm doing solgar dry beta carotene and just added chondroitin today. With preformed retinol, it's just too easy to overdose. With beta carotene, it's impossible to overdose on vitamin A. Natural beta carotene is better than synthetic, and dry is better than oil based.
Chondroitin is loaded with glucuronic acid, which forms with accutane via glucuronidation to be excreted by the body. Will see how it goes.
The anti vitamin A ppl basically went overboard. It's wise to avoid things like non defatted beef liver and cod liver oil, which are loaded with retinol. But it's not smart to avoid organic dairy, which is loaded with essential nutrients like omega fatty acids and calcium. Carrots, pumpkin, apricots, and sweet potatoes are also excellent choices for accutane ppl. It's easy to get sick of beta carotene foods, so the solgar dry beta carotene helps with that.
I think I've found why accutane prematurely closes the bone growth plates. The body needs extra amounts of glucuronic acid to get rid of accutane. This depletes the body of chondroitin, which is a crucial factor in bone growth plates health. Starve the body of glucuronic acid and chondroitin and the growth plates close.
2 hours ago, Tommy Ballgame said:I think I've found why accutane prematurely closes the bone growth plates. The body needs extra amounts of glucuronic acid to get rid of accutane. This depletes the body of chondroitin, which is a crucial factor in bone growth plates health. Starve the body of glucuronic acid and chondroitin and the growth plates close.
mangenese is the cofactor for glucuronic acid. thats why its put in products like osteo-biflex.
Manganese is a cofactor but not the main factor. Glucuronic acid is what attaches to accutane to be excreted from the body. Chondroitin is likely the best source of glucuronic acid.
https://pubmed.ncbi.nlm.nih.gov/2870901/
5 hours ago, Tommy Ballgame said:Manganese is a cofactor but not the main factor. Glucuronic acid is what attaches to accutane to be excreted from the body. Chondroitin is likely the best source of glucuronic acid.
https://pubmed.ncbi.nlm.nih.gov/2870901/
manganese could be a rate limiting step is my point
Carbohydrate Chain Synthesis Utilizing Glycosyltransferases
Glycosyltransferases are enzymes that catalyze the transfer of activated monosaccharide donors to carbohydrates during the biosynthesis of oligosaccharides. They are very useful in synthesizing oligosaccharides in vitro because they exhibit high regioselectivity and stereoselectivity in the formation of glycosidic bonds. Glycosyltransferases that utilize nucleotide sugars as activated monosaccharide donors have often been used in the in vitro synthesis of carbohydrate chains . A wide variety of oligosaccharide structures can be produced using the available glycosyltransferases and activated nucleotide sugars such as UDP-glucose (UDP-Glc), UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-galactose (UDP-Gal), UDP-N-acetylgalactosamine (UDP-GalNAc), UDP-glucuronic acid (UDP-GlcUA), GDP-mannose (GDP-Man), GDP-fucose (GDP-Fuc), and CMP-sialic acid (CMP-NeuAc).
https://pubmed.ncbi.nlm.nih.gov/819265/
14 hours ago, Calcified said:How much and what type vit A you taking? If you don't mind me asking.
Epigenetics Activator X
They are oil drops, combo of Vit A, D and K
Only been on them three days, body saying 2 drops a day at this stage, prob build up to 10 drops and eventually 20 drops.This makes sense as Im still clearing lymphatic especially around the brain. So the idea is toget rid of the bad shit and replenish with the good stuff.
Todays session we worked on correcting Copper and Iron issues. Without me prompting, thekinesiologist also picked up on OCD sensory issue - we all know what thats like post tane.
Ive got crusty stuff falling from my ears and they are very itchy which is connected to the lymphatic draining
Interesting. I can recall crusty crumbs coming out of my ears several years ago when supplementing with mistletoe, which is known to activate the sebaceous glands. I think accutanes extreme polarity (13 cis, 0 trans) causes not only ocd but also bipolar issues as well. Remove the poison and eliminate ocd and bipolar issues.
For the brain, my biofeedback machine has indicated ocd, neuralgia, dicirculatory encephalopathy, atherosclerosis, manic depressive, schizophrenia, epilepsy. The crazy items from that list were very low grade, but they do appear from time to time. Atherosclerosis has been the most prominent brain issue.
4 hours ago, tryingtohelp2014 said:manganese could be a rate limiting step is my point
Carbohydrate Chain Synthesis Utilizing Glycosyltransferases
Glycosyltransferases are enzymes that catalyze the transfer of activated monosaccharide donors to carbohydrates during the biosynthesis of oligosaccharides. They are very useful in synthesizing oligosaccharides in vitro because they exhibit high regioselectivity and stereoselectivity in the formation of glycosidic bonds. Glycosyltransferases that utilize nucleotide sugars as activated monosaccharide donors have often been used in the in vitro synthesis of carbohydrate chains . A wide variety of oligosaccharide structures can be produced using the available glycosyltransferases and activated nucleotide sugars such as UDP-glucose (UDP-Glc), UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-galactose (UDP-Gal), UDP-N-acetylgalactosamine (UDP-GalNAc), UDP-glucuronic acid (UDP-GlcUA), GDP-mannose (GDP-Man), GDP-fucose (GDP-Fuc), and CMP-sialic acid (CMP-NeuAc).
https://pubmed.ncbi.nlm.nih.gov/819265/
My point is there's no need to worry about manganese if you go directly to an external source of glucuronic acid with a chondroitin sulfate supplement. No need for the body to have to produce it that way.
I've been back and forth many times on the idea of accutane trapped in the body vs accutane is gone, but left permanent damage.Will try testing this ongoing question with a Statin drug hopefully this week. Likely Lovastatin. See the following studies and connect the dots. Use the find in page feature for the second link and type statin.
https://pubmed.ncbi.nlm.nih.gov/18445226/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121510/
https://pubmed.ncbi.nlm.nih.gov/30448601/
My machine has indicated atherosclerosis quite often. Sometimes Lovastatin shows up for liver scans. Statins antagonize the rxr receptor, which is one of the receptors that accutane targets. I can recall having chest pains when I was younger. My machine also indicates cholangitis virtually every scan. Statins have been shown to address cholangitis. Will see how it goes.
http://blog.arthritis.org/osteoarthritis/osteoarthritis-statins/
Another study stating statins can be helpful for joint issues. What if it's not just vitamin A that we are needing, but essentially ALL fat soluble vitamins, because our bile flow is messed up, which can possibly be fixed with a Statin drug such as Lovastatin.
Got bad news, all the special values from the Neurosteroid study cannot be determined in serum or liquor. I will do a regular blood test next week and determine LH and FSH bc it was lowish in people with the syndrome. I did some research and found the following:
Low Allo leads to HPA hyperactivity, which we have. HPA hyperactivity leads to too much glucocorticoids which inhibit the secretion of GnRH. GnRH has the task to stimulate LH and FSH production and if it's inhibited this causes low LH and FSH. The guy who took the mifepristone had low LH/FSH which went up a lot after taking mifepristone. My doctor will tell me about the risk profile of this drug, for now I read it has a good safety profile.
I want to try out a treatment soon.
17 hours ago, TrueJustice said:How long is one on it for?
Does it fix something and thats it, you dont have to take anymore?
For 7 days. The guy who took it said 2 and a half week after taking it he felt cured which lasted for 6 months. As far as I know he now takes progesterone 10 mg daily. His prog was too high prior mife and now it's normal, he thinks it is now absorbed by the body. He feels 90 % cured now this way.
https://www.rxlist.com/consumer_mifepristone_mifeprex/drugs-condition.htm
The above link provides mifepristone side effects. It was foolish of me to even think about statins. Have not and will not try a Statin or other drug.
Also just switched from solgar dry beta carotene to now foods natural beta carotene. The solgar product has toxic fillers that I didn't think would be a problem, but they are. The now foods natural beta carotene product is clean.also doing organic ginger for gut support and broccoli sprouts for liver support. Will see how it goes.
Vitamin A regulates not only the dopaminergic system, but also the hpa. Vitamin A deficiency results in dysfunctional hpa axis.
1 hour ago, TrueJustice said:To be clear, we must be the only males taking it right?
When else would a male take this drug other than trying to fix Accutane problems?
Its really still an experiment in that regard Id have to say
No it's used for Cushings syndrome where people take it up to 6 weeks and 'state of the art' for major depressive disorder:
3 hours ago, TrueJustice said:To be clear, we must be the only males taking it right?
When else would a male take this drug other than trying to fix Accutane problems?
Its really still an experiment in that regard Id have to say
How your drops going? I looked into them sounds good, seems too favour vitamin D. Would probably make me too oily.