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13 hours ago, TrueJustice said:thanks again - really good info and appreciate being educated on hormone production
What areyour thoughts on Leydig Cell death? Mentioned by someone on one of the previous pages. If theres any truth to it, it sounds pretty dire if true yeah?
There are a few studies of the effects accutane has on leydig cells and spermatogenesis. Some say there is no difference. Others say it causes alterations in the cytoplasm of leydig cells and other studies say it actually improves sperm production. So i don't really know.
Accutane causesapoptosis (programmed cell death). That's why it works so good to treat acne. The sebocytes that cause acne die so there is no chance for acne to survive. It can have the same effect on other cells in the body. Accutane downregulates igf-1 (needed for cellproliferationand survival) and upregulates foxo (foxo genes cause cell death). In theory, after you stop treatment, things should go back to normal. But if you developed some degree of insulin resistance and your pro-apoptotic genesstay activated, it will become a long-term problem. So i still think the problem is insulin resistance which effects gene transcription (your body doesn't respond well to insulin and growth factors andgenes that cause cell death stay activated). And the reason is chronic inflammation.
3 hours ago, Lifesuckshard said:There are a few studies of the effects accutane has on leydig cells and spermatogenesis. Some say there is no difference. Others say it causes alterations in the cytoplasm of leydig cells and other studies say it actually improves sperm production. So i don't really know.
Accutane causesapoptosis (programmed cell death). That's why it works so good to treat acne. The sebocytes that cause acne die so there is no chance for acne to survive. It can have the same effect on other cells in the body. Accutane downregulates igf-1 (needed for cellproliferationand survival) and upregulates foxo (foxo genes cause cell death). In theory, after you stop treatment, things should go back to normal. But if you developed some degree of insulin resistance and your pro-apoptotic genesstay activated, it will become a long-term problem. So i still think the problem is insulin resistance which effects gene transcription (your body doesn't respond well to insulin and growth factors andgenes that cause cell death stay activated). And the reason is chronic inflammation.
Igf1 doesn't seem to stay low and in alot of cases eventually acne returns. But I do agree regarding insulin issues, I've only ever reduce mine to a more healthier number by fasting, even low carb didn't dent it had to stop eating altogether.
1 hour ago, Calcified said:Igf1 doesn't seem to stay low and in alot of cases eventually acne returns. But I do agree regarding insulin issues, I've only ever reduce mine to a more healthier number by fasting, even low carb didn't dent it had to stop eating altogether.
I still get acne but it's not like before. My skin was very oily and that never returned. I used to have big pimples all the time and now i only get little spots that go away quickly. I'm happy for havingclear skin but the hair was becoming a big problem. If my hair wasn't effected, i would have moved on with with my life after quitting accutane. My lips also stayed dehydrated for a long time after quitting accutane but they are finally hydrated again. I don't know if that's because of fin but it's since starting fin that my lips are suddenly much better. I'm still not fully recovered from accutanebut it's going in the right direction.
Ialso had my doubts to start fin and it took me almost a year to start treatment, but i can confirm after 2 months that i don't have any (negative) side effects. Most of you probably don't want to take another drug with the potential of scary side effects, but for my personal case i didn't feel like i had anything to lose (and my hair was too important for me). I was already having many of the side effects fin could cause (depression, anxiety, brain fog and low energy). Erection problems were the only potential side effects i didn't have already. But i don't have any problems with that so far. Libido is also uneffected and it's actuallyeven better (possibly because of better T/estradiol balance).
I really think low SHBG (because of insulin resistance) and free testosterone (because too much was converted to DHT and this caused too low estradiol) was a problem and fin somehow pushed it back in the right direction. The underlying problem is probably still there and i would need to fix the insulin issues for that (possibly with something like TZD's). If fin is really able to raise SHBG, that would explain a lot. But it's just people on propeciahelp who report raised SHBG and no studies.
8 hours ago, Lifesuckshard said:There are a few studies of the effects accutane has on leydig cells and spermatogenesis. Some say there is no difference. Others say it causes alterations in the cytoplasm of leydig cells and other studies say it actually improves sperm production. So i don't really know.
Accutane causesapoptosis (programmed cell death). That's why it works so good to treat acne. The sebocytes that cause acne die so there is no chance for acne to survive. It can have the same effect on other cells in the body. Accutane downregulates igf-1 (needed for cellproliferationand survival) and upregulates foxo (foxo genes cause cell death). In theory, after you stop treatment, things should go back to normal. But if you developed some degree of insulin resistance and your pro-apoptotic genesstay activated, it will become a long-term problem. So i still think the problem is insulin resistance which effects gene transcription (your body doesn't respond well to insulin and growth factors andgenes that cause cell death stay activated). And the reason is chronic inflammation.
its taken so long for me to get to this point of understanding whats really going on, took it 1998 so now into 23rd year of spending my time and directing my thoughts to fixing this mess. To me life has been on hold for all this time
An insulin issue hasnt been on the radar till now, had no idea there was a problem with it.Chronic inflammation Ive known for sometime even though blood tests have never revealed anything. What do you do for it though?? None of the so called supplements prevent anything in my book. All you can do is cut out foods that might cause more inflammation, other than that Ive got no clue.
Thanks
2 hours ago, TrueJustice said:its taken so long for me to get to this point of understanding whats really going on, took it 1998 so now into 23rd year of spending my time and directing my thoughts to fixing this mess. To me life has been on hold for all this time
An insulin issue hasnt been on the radar till now, had no idea there was a problem with it.Chronic inflammation Ive known for sometime even though blood tests have never revealed anything. What do you do for it though?? None of the so called supplements prevent anything in my book. All you can do is cut out foods that might cause more inflammation, other than that Ive got no clue.
Thanks
23 years is such a long time. I'm almost 21 now and took it 2 years ago when i was 18. At first i was very happy with the clear skin but after a while i was feeling depressed and at first i didn't know why. My acne was making me miserable for yearsand i thought life would be perfect without it. But then i realized my hair went to shit (this was months after i quit accutane) and i suddenly regretted everything. It's confirmed by mri i have brain lesions (not sure it's because of accutane but it caused even more regret). Now i'm on fin and happy with my hair again. Lips are also back to normal so i'm trying to leave this all behind me.
I came to a point i'm just living my life normally and realised it could be worse. My joints are fine and i never got bad sexual sides like a lot of you. But i know i developed insulin resistane to some degree because my bloodsugar was borderline high and i can't gain any weight or muscles. I also had digestive issues but these are not that bad anymore. I'm staying positive and keep telling myself at least i have clear skin now (because i don't want this to be for nothing afterall). But i would probably not take it if i could go back in time.
I also don't think supplements help much. Just living very healthy is the best you can do. Some people reported fasting helps short-term and that's because it improves insulin sensitivity temporary, but it will probably not do much long-term.
The problem with accutane is it causes a wide variety of problems and we all seem to have different issues but i think this (chronic inflammation causing insulin resistance which also effects hormones) explains a lot. Idid a lot of research the past year and this explains most problems accutane caused and would be the most logical explanation, at least for my personal case.
No constipation here. Loose stools has been more of an issue for me. I believe a lot of people who took accutane and say they're fine after it aren't really paying attention to their health, and/or they never really knew what healthy felt like before accutane.
After all the horror stories I've read about propecia, I have an extremely hard time believing it's helping anyone to feel and function better. I'm sorry, I'm just being honest.
Any thoughts on treating isotretinoin induced skin problems with growth hormone? Growth hormone can thicken skin and increase sebaceous gland size so it sounds good. Anyway I started using MK-677 to increase GH a few days ago (10mg/day). It also increases IGF1. Latest posts got me second guessing since it can reduce insulin sensitivity. I've got my plasma glucose tested though and it was ok. I'll update here about my results later.
6 hours ago, Aaron76 said:No constipation here. Loose stools has been more of an issue for me. I believe a lot of people who took accutane and say they're fine after it aren't really paying attention to their health, and/or they never really knew what healthy felt like before accutane.
After all the horror stories I've read about propecia, I have an extremely hard time believing it's helping anyone to feel and function better. I'm sorry, I'm just being honest.
I wouldn't take propecia if your hair is still fine (or if you don't care about it). It effects hormones and for some, this can cause bad side effects. It will increase total T and more will be converted to estradiol via aromatase. I don't know how it could increase SHBG but many people report this.
But if your hormones are already unbalanced, maybe it can have a positive effect. I'vealso read all horror stories, but i didn't feel like i had much to lose (especially mentally). And i wouldn't say it makes me function better, i'm just happy because my hair is better. And my lips are somehow much better.
19 hours ago, Lifesuckshard said:I still get acne but it's not like before. My skin was very oily and that never returned. I used to have big pimples all the time and now i only get little spots that go away quickly. I'm happy for havingclear skin but the hair was becoming a big problem. If my hair wasn't effected, i would have moved on with with my life after quitting accutane. My lips also stayed dehydrated for a long time after quitting accutane but they are finally hydrated again. I don't know if that's because of fin but it's since starting fin that my lips are suddenly much better. I'm still not fully recovered from accutanebut it's going in the right direction.
Ialso had my doubts to start fin and it took me almost a year to start treatment, but i can confirm after 2 months that i don't have any (negative) side effects. Most of you probably don't want to take another drug with the potential of scary side effects, but for my personal case i didn't feel like i had anything to lose (and my hair was too important for me). I was already having many of the side effects fin could cause (depression, anxiety, brain fog and low energy). Erection problems were the only potential side effects i didn't have already. But i don't have any problems with that so far. Libido is also uneffected and it's actuallyeven better (possibly because of better T/estradiol balance).
I really think low SHBG (because of insulin resistance) and free testosterone (because too much was converted to DHT and this caused too low estradiol) was a problem and fin somehow pushed it back in the right direction. The underlying problem is probably still there and i would need to fix the insulin issues for that (possibly with something like TZD's). If fin is really able to raise SHBG, that would explain a lot. But it's just people on propeciahelp who report raised SHBG and no studies.
I too have been on fin after accutane, what I found is about 6 years after accutane there is very little dryness, and in some skin areas more sebum and inflammation.
Regarding fin I took it about 7 years after accutane and my hair loss was not stopped.
I did get a large dose of accutane, so everyone may get different outcomes.
Fancy being cornered like this where you feel the bestoption is to take another dangerous drug to unravel this mess
There must be other safer options available surely...
My hair has no doubt thinned, its dry and wiry but Im not balding so wouldnt be interested in taking fin
1 hour ago, TrueJustice said:Fancy being cornered like this where you feel the bestoption is to take another dangerous drug to unravel this mess
There must be other safer options available surely...
My hair has no doubt thinned, its dry and wiry but Im not balding so wouldnt be interested in taking fin
Don't know why but vitamin A seems to soften my hair now.
On 24/5/2021 at 0:27, Aaron76 said:Aqui no hay estrenimiento. Las heces sueltas han sido un problema mayor para mi. Creo que muchas personas que tomaron accutane y dicen que estan bien despues de que realmente no estan prestando atencion a su salud, y / o nunca supieron realmente como se sintio saludable antes de accutane.
Despues de todas las historias de terror que he leido sobre la propecia, me cuesta mucho creer que este ayudando a cualquiera a sentirse y funcionar mejor. Lo siento, solo estoy being honesto.
Wow, I never thought it would be so strong, the constipation is gone. My stools are returning to normal but I have thinner and normal stools of normal color and they sink with a bowel movement frequency 2 or 1times a day of 3 or 2 as before, I have no pain in my body, I have no dry eyes, lips Dry hair, hair loss, dry skin is gone and the sebum is back thank goodness. I am taking probiotics to get better. My lower lip is a little dry, but it is from the change of weather.my liver tests are perfect and the abdominal CT showed everything fine.
God is helping me improve, yes I trust him, he is my rock. in 6 or 10 days it will be 2 months since I stopped accutane.
if someone has dry lips after finishing a long period of accutane (+4 months) it is because accutane reduces all the glands of the body, including the lacrimal and salivary glands, which lubricate the eyes, skin, hair, body and sweat glands. .
Hair loss occurs because Accutane destroys the sebaceous glands that lubricate the hair, when the hair loses its lubrication it becomes loose.
Sorry to mention it, I hope many will read it, I am sure we will win.
my data can help other people who go through the same And God bless the reader and all who are victims of the pharmaceutical monopoly as there are thousands of drugs with worse effects than accutane.
On 5/24/2021 at 3:55 AM, george20 said:Problems with this stupid drug are more common than I imagined,I only lasted 15 days with this drug since I started to have constipation, 2 months have passed and the problems continues, has this happened to some else?
You still taking it?
On 6/16/2021 at 6:51 PM, timetoban said:Everyone made huge effort with the MHRA call for information. They have now asked for people to speak to the EWG. Last day to apply is Thurday17th June. Registration only takes 1 minute.Or else you can still send you case history/experience or any other info to the email address below. If you have a dermatologists on side(which I doubt) please get them to contribute.Patient and other stakeholder views are an essential part of this review of isotretinoin. If you are not able to present to the IEWG in this instance and you have additional new information you wish to share with them, please email us at [email protected] by Friday, 16 July 2021.Thanks everyone, much appreciatedYou still taking it?
No, A soon as I started to feel constipated, let the medicine(15 days),I remember feeling intestinal pain, but it has improved 90%,and the bowel movements are varied, but every day I go. When I say varied, it means that I go 1 or 2 times a day, but generally 2 times.
On 5/22/2021 at 6:55 AM, Lifesuckshard said:For the testosterone issues, if you haven't checked your SHBG yet you should do this. If it's low, that means inflammation (and chronic inflammation causes insulin resistance). Low SHBG means your sex hormones are rapidly destroyed by the liver, even if testosterone production is normal. And low T could cause higher cholesterol, but cholesterol is also needed to produce T so it's a bit complicated. I would test SHBG because this can tell you a lot.
I took accutane 15 years ago.
After 6 weeks, of taking the drug, I became severally constipated with great abdominal discomfort. After a few more days, I went to the emergency department at the the hospital because things werent getting any better. It was thought that I had missed appendicitis. It was then determined that I had Crohns Disease. This would lead to surgery to remove the damaged intestine. I had a total of 7 feet of small, 1 foot of large and the cecum/ileum area removed. Complications arose and I would require another surgery to have a temporary ileostomy for 18 months, so that I could eat and heal. I went from 222 lbs down to 131 lbs.
I had the ileostomy reversal surgery and noticed my hands and feet swelling. I went to an urgent care and they never had an answer. Time went on and I found that I was hungry, extremely hungryall of the time! My sleep declined to 1-2 hours per night. 2 hours was seldom. I went on vacation and my mother took notice of my situation and the change in food and sleep habits, but more importantly, the attitude/personality changes. I become someone that I was not. In addition to my hands and feet, my face was swollen as well, especially my nose. I scheduled a doctors appointment.
Returning home I visited an endocrinologist whom I was referred to by my family physician. He determined that I could have a pituitary tumour. The saddest day yet. I did another blood test and he noticed that my IGF-1 was through the roof. A reading of almost two thousand where the normal was under two hundred. The MRI proved this, and the tumour was almost 3 cm in diameter. They scheduled the transsphenoidal surgery.
The neurosurgeon said, the surgery went well and that the tumour peeled off nicely. Unfortunately, I developed bacterial meningitis, which required a spinal tap, and another few weeks in the hospital.
I now see the endocrinologist every six months. A few years after surgery, 7 years ago, my blood results showed normal IGF-1, but now determined that I had high SBGH. A 99.9 reading, and sadly, almost a perfect score. He gave me testosterone administered nasally twice daily, I believe. I couldnt take it as it had a mental impact on me, and my anxiety. Oddly, he said said they stopped producing this type of testosterone. I havent enquired about any other types of testosterone because Im somewhat afraid because of how I reacted to the first doses. It didnt work for me, but I maybe I didnt give it enough time. I felt worse and angry when I took it, so that is why I stopped. It was also determined that I have high sodium which seems minor at this point.
I experience issues with Crohns Disease every day. I dont sit upright well. I lie in bed 80% or more of the time. My current battle is anxiety. OCD was developed too 6-7 years ago. I have panic attacks with extreme sweating and shaking. Brain fog once caused me to wash my hands for 3 hours. I notice that eating sugar/candy eases the anxiety, but obviously doesnt cure it. I go to the gym regularly, but have stopped exercising due to covid lockdowns and the gyms being closed. Public washrooms were closed too, so venturing off by foot wasnt an option for someone with Crohns.
When eating healthier choices of food and then start losing body fat, I become extremely anxious. When exercising, I have to push super hard to see results. And if I do see results, they go away as I have a constant hunger for sugary foods. It seems as if my insulin wants to be high all of time. Or my blood sugar doesnt like to be low. High insulin is reducing my testosterone which will not allow me to gain muscle.
My SHBG (sex hormone binging globulin) is still high, not 99, but still around 75. I need to get it to 50ish, but I cant. It seems impossible. There isnt a drug or anything that can help reduce SHBG. That is why the doctors prescribe testosterone, but my testosterone levels are normal. There is a correlation between the high SHBG and my anxiety. When I developed the OCD, my SHBG was severally high. Unfortunately, my testicles have decreased in size too.
I once read here, 2 years ago, that someone mentioned to look at the liver and the kidneys for the problems we are experiencing. I remember years ago getting a CT scan on my liverand theradiologist seeing something abnormal on theimages. I now want to investigate this further, but not sure how itll help.
I used to monitor my blood sugar, via a glucometer, and noticed it would drop in the red zone a few times. I remember the feeling, the shaking, the sweating. Where a reading of 5-6 was normal, I was getting a reading of 1 when feeling this way. It was hard to preform the test as I was shaking and had a horrible, bad mood.
I ate chili last night with no sugar. After 20 minutes or so I had the shaking, sweating and pissy mood. Little bit of brain fog too and hard to focus and concentrate. Not sure of what to do now
High SBGH basically means most of you testosterone is bound up, and thus not delivered into your tissues. In Men, low serum Testosterone is a risk factor for insulin resistance. In Women, the correlation is reversed. High Androgen levels in women leads to insulin resistance.
The better way to manage Low Testosterone is taking DHEA.
I also agree that the root issue is chronic inflammation. Unfortunately insulin resistance, high cholesterol leads to further inflammation, metabolic disease syndrome,thus creating a vicious cycle causing people to suffer years after stopping Accutane. It won't stop until this cycle is stopped somehow.
There is only one way to treat Post Accutane disease, and that is EXERCISE. Persistent, daily, weekly, yearly exercise.
6 hours ago, JTM88 said:There is only one way to treat Post Accutane disease, and that is EXERCISE. Persistent, daily, weekly, yearly exercise.
I totally agree that exercising helps. The sweating,increased heart rate and the burn just feels so darn good.Having Crohns, I can attest that it has helped me with the negative symptomsimmensely.
My anxiety can be settled by working out, but it is hit or miss.I find that eating/not eating/changes in diet can exasperate it.Im still not quite sure why sugar calms it, though.Sometimes when eating junk food I becomesuper tired. I nod off, but I dont fall asleep. This feeling of fatigue lasts for 15-20 minutes. Im 99% sure that this stateis a sugar crash as it happens only minutes after. I recall that when I took vitamin D supplements that anxiety would increase. I read that Vitamin D is in fact a hormone. hmnmn. Are there any supplements that help with utilizing the little Testosterone that I already have.?Now I can see why I have smaller testes. Effing Accutane!!!
I wonder if the high SHBG and thelack of testosterone utilized by me is the cause of myanxiety. Im definitely having a difficult time building muscle. Sleep is also messed up.
I have an upcoming endocrinologist appointment. Im going to ask him to prescribe T once again. This timein the form of a shot rather than a spray or gel. (Ive read the shotis the best method).Im wondering what type of dose is ideal? Im now 226lbs. Male, obviously, since I have testicles although smaller. Lol
My daily regimen:
Exercise
Healthy diet
Testosterone
3 hours ago, oneaway said:I totally agree that exercising helps. The sweating,increased heart rate and the burn just feels so darn good.Having Crohns, I can attest that it has helped me with the negative symptomsimmensely.
My anxiety can be settled by working out, but it is hit or miss.I find that eating/not eating/changes in diet can exasperate it.Im still not quite sure why sugar calms it, though.Sometimes when eating junk food I becomesuper tired. I nod off, but I dont fall asleep. This feeling of fatigue lasts for 15-20 minutes. Im 99% sure that this stateis a sugar crash as it happens only minutes after. I recall that when I took vitamin D supplements that anxiety would increase. I read that Vitamin D is in fact a hormone. hmnmn. Are there any supplements that help with utilizing the little Testosterone that I already have.?Now I can see why I have smaller testes. Effing Accutane!!!
I wonder if the high SHBG and thelack of testosterone utilized by me is the cause of myanxiety. Im definitely having a difficult time building muscle. Sleep is also messed up.
I have an upcoming endocrinologist appointment. Im going to ask him to prescribe T once again. This timein the form of a shot rather than a spray or gel. (Ive read the shotis the best method).Im wondering what type of dose is ideal? Im now 226lbs. Male, obviously, since I have testicles although smaller. Lol
My daily regimen:
Exercise
Healthy diet
Testosterone
DHEA helps with Testosterone, so doestongkat Ali. Testosterone plays so many critical roles in men's health, including sleep. Low Testosterone is a known factor in chronic insomnia.
Eating sugar is not a long term solution to dealing with anxiety. Sugar, refined carbs will exacerbate insulin resistance and inflammation. The best way to manage anxiety and naturally increase testosterone is again through Exercise and diet.
There are no magic pills out there that can match the hundreds of chemicals released through aerobic exercise. Keep it up, don't give up hope.
On 6/19/2021 at 6:07 PM, oneaway said:I took accutane 15 years ago.
After 6 weeks, of taking the drug, I became severally constipated with great abdominal discomfort. After a few more days, I went to the emergency department at the the hospital because things werent getting any better. It was thought that I had missed appendicitis. It was then determined that I had Crohns Disease. This would lead to surgery to remove the damaged intestine. I had a total of 7 feet of small, 1 foot of large and the cecum/ileum area removed. Complications arose and I would require another surgery to have a temporary ileostomy for 18 months, so that I could eat and heal. I went from 222 lbs down to 131 lbs.
I had the ileostomy reversal surgery and noticed my hands and feet swelling. I went to an urgent care and they never had an answer. Time went on and I found that I was hungry, extremely hungryall of the time! My sleep declined to 1-2 hours per night. 2 hours was seldom. I went on vacation and my mother took notice of my situation and the change in food and sleep habits, but more importantly, the attitude/personality changes. I become someone that I was not. In addition to my hands and feet, my face was swollen as well, especially my nose. I scheduled a doctors appointment.
Returning home I visited an endocrinologist whom I was referred to by my family physician. He determined that I could have a pituitary tumour. The saddest day yet. I did another blood test and he noticed that my IGF-1 was through the roof. A reading of almost two thousand where the normal was under two hundred. The MRI proved this, and the tumour was almost 3 cm in diameter. They scheduled the transsphenoidal surgery.
The neurosurgeon said, the surgery went well and that the tumour peeled off nicely. Unfortunately, I developed bacterial meningitis, which required a spinal tap, and another few weeks in the hospital.
I now see the endocrinologist every six months. A few years after surgery, 7 years ago, my blood results showed normal IGF-1, but now determined that I had high SBGH. A 99.9 reading, and sadly, almost a perfect score. He gave me testosterone administered nasally twice daily, I believe. I couldnt take it as it had a mental impact on me, and my anxiety. Oddly, he said said they stopped producing this type of testosterone. I havent enquired about any other types of testosterone because Im somewhat afraid because of how I reacted to the first doses. It didnt work for me, but I maybe I didnt give it enough time. I felt worse and angry when I took it, so that is why I stopped. It was also determined that I have high sodium which seems minor at this point.
I experience issues with Crohns Disease every day. I dont sit upright well. I lie in bed 80% or more of the time. My current battle is anxiety. OCD was developed too 6-7 years ago. I have panic attacks with extreme sweating and shaking. Brain fog once caused me to wash my hands for 3 hours. I notice that eating sugar/candy eases the anxiety, but obviously doesnt cure it. I go to the gym regularly, but have stopped exercising due to covid lockdowns and the gyms being closed. Public washrooms were closed too, so venturing off by foot wasnt an option for someone with Crohns.
When eating healthier choices of food and then start losing body fat, I become extremely anxious. When exercising, I have to push super hard to see results. And if I do see results, they go away as I have a constant hunger for sugary foods. It seems as if my insulin wants to be high all of time. Or my blood sugar doesnt like to be low. High insulin is reducing my testosterone which will not allow me to gain muscle.
My SHBG (sex hormone binging globulin) is still high, not 99, but still around 75. I need to get it to 50ish, but I cant. It seems impossible. There isnt a drug or anything that can help reduce SHBG. That is why the doctors prescribe testosterone, but my testosterone levels are normal. There is a correlation between the high SHBG and my anxiety. When I developed the OCD, my SHBG was severally high. Unfortunately, my testicles have decreased in size too.
I once read here, 2 years ago, that someone mentioned to look at the liver and the kidneys for the problems we are experiencing. I remember years ago getting a CT scan on my liverand theradiologist seeing something abnormal on theimages. I now want to investigate this further, but not sure how itll help.
I used to monitor my blood sugar, via a glucometer, and noticed it would drop in the red zone a few times. I remember the feeling, the shaking, the sweating. Where a reading of 5-6 was normal, I was getting a reading of 1 when feeling this way. It was hard to preform the test as I was shaking and had a horrible, bad mood.
I ate chili last night with no sugar. After 20 minutes or so I had the shaking, sweating and pissy mood. Little bit of brain fog too and hard to focus and concentrate. Not sure of what to do now
what were your symptoms? I took the medicine for 15 days and began to constipate and feel abdominal pain, but I already stopped and I have been off accutane for 2 months,but I'm still improving, my stools are varied but not like beforeand I no longer feel abdominal pain.
On 6/21/2021 at 3:31 PM, george20 said:what were your symptoms? I took the medicine for 15 days and began to constipate and feel abdominal pain, but I already stopped and I have been off accutane for 2 months,but I'm still improving, my stools are varied but not like beforeand I no longer feel abdominal pain.
My initial symptoms were exactly those, abdominal pain and constipation.
Accutane was a drug made to cure coloncancer. They found that it also helped with the reduction of acne. Itstrips the lining of your intestines. Certain things eg toxins thencant be absorbed, so no new acne. Also, it messes with ones hormoneseg.testosterone reduction, and that also prevents acne. Blood sugar is altered too.
Aftet I had a CT scan and a colonoscopy they saw a mass at the cecum, located where the small intestine meets the large intestine. My hypothesis is,the small intestine was stripped of its lining then itgatheredat the cecum/ileum creating an obstruction (the mass).
The doctors did a bowel resection. After that, I had major issues because the bowel was not sealed up well. They used staples to seal and attach the small to the large intestine. This is when my weight dropped over 90lbs. I then had an ileostomy put in because I was literally dying. 18 months later they reversed it and this time I asked for stitches rather than thoseworthlessstaples. Still rocking it to this day without any bowel surgeries. However, when I was going through this trauma, I noticed I couldnt think properly. Didnt know what the heck was going on, but this was when the pituitary tumour was impacting my mentality.
They then removed the tumour, and now Istill have testosterone/SHBG, andinsulin/blood sugarissues, Crohns Disease, andanxiety plague me as well.